Abstract：
:Parkinson's disease (PD) typically occurs in elderly people and some degree of cognitive impairment is usually present. Cognitive reserve (CR) theory was proposed to explain the discrepancy between the degree of brain pathologies and clinical manifestations. We administered a comprehensive neuropsychological battery to 35 non-demented participants affected by PD. All participants underwent also the Cognitive Reserve Index questionnaire and the Brief Intelligence Test as proxies for CR. Relationships between CR and cognitive performance were investigated by linear regression analyses, adjusting for significant confounding factors. At linear regression analyses, higher CR scores were independently associated with a better performance on Word Fluency (p ≤ 0.04) and Digit Span (backward) (p ≤ 0.02); no associations were observed between CR and other cognitive tests. Our data provide empirical support to the relation between CR and cognitive impairment in PD. In particular, this study suggests that CR may have greater effects on the cognitive areas mostly affected in PD as executive functions.
journal_name
Aging Clin Exp Resjournal_title
Aging clinical and experimental researchauthors
Ciccarelli N,Monaco MRL,Fusco D,Vetrano DL,Zuccalà G,Bernabei R,Brandi V,Pisciotta MS,Silveri MCdoi
10.1007/s40520-017-0838-0subject
Has Abstractpub_date
2018-07-01 00:00:00pages
877-880issue
7eissn
1594-0667issn
1720-8319pii
10.1007/s40520-017-0838-0journal_volume
30pub_type
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journal_title：Aging clinical and experimental research
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journal_title：Aging clinical and experimental research
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doi：10.1007/s40520-016-0576-8
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journal_title：Aging clinical and experimental research
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章,随机对照试验
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journal_title：Aging clinical and experimental research
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
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journal_title：Aging clinical and experimental research
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journal_title：Aging clinical and experimental research
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journal_title：Aging clinical and experimental research
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更新日期：2020-07-01 00:00:00
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03327370
更新日期：2003-12-01 00:00:00
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章
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更新日期：2013-08-01 00:00:00
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s40520-018-1090-y
更新日期：2019-10-01 00:00:00
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03325209
更新日期：2007-02-01 00:00:00
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324842
更新日期：2006-10-01 00:00:00
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/s40520-019-01359-4
更新日期：2019-10-03 00:00:00
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/s40520-016-0622-6
更新日期：2017-08-01 00:00:00
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章
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journal_title：Aging clinical and experimental research
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更新日期：2012-08-01 00:00:00
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更新日期：2017-10-01 00:00:00
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-013-0130-x
更新日期：2013-10-01 00:00:00
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/s40520-019-01191-w
更新日期：2019-06-01 00:00:00
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-016-0606-6
更新日期：2017-08-01 00:00:00
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章
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更新日期：2019-01-01 00:00:00
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journal_title：Aging clinical and experimental research
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
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更新日期：2012-04-01 00:00:00
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journal_title：Aging clinical and experimental research
pub_type： 杂志文章,多中心研究
doi：10.1007/s40520-016-0644-0
更新日期：2017-02-01 00:00:00
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journal_title：Aging clinical and experimental research
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更新日期：2005-02-01 00:00:00
