An overview of standard statistical methods for assessing exposure-outcome link in survival analysis (Part I): basic concepts.

abstract：BACKGROUND:Oxidative stress has been considered one of the causes of aging. For this reason, treatments based on antioxidants or those capable of increasing endogenous antioxidant activity have been taken into consideration to delay aging or age-related disease progression. AIM:In this paper, we determine if resveratr...

journal_title：Aging clinical and experimental research

authors： Tung BT,Rodriguez-Bies E,Thanh HN,Le-Thi-Thu H,Navas P,Sanchez VM,López-Lluch G

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Few studies have explored the activity levels of hospitalised older people and the intra-daily activity patterns in this group have not been described. AIMS:To describe the quantity and daily pattern of physical activity among hospitalised older people using two accelerometers: the ankle-worn StepWatch Acti...

journal_title：Aging clinical and experimental research

authors： Lim SER,Dodds R,Bacon D,Sayer AA,Roberts HC

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Fragility fracture significantly increases risk of future fracture. The fragility fracture cycle should be disrupted. The secondary fracture prevention is important for the patients with fragility hip fracture. The pharmacotherapy for osteoporosis is important for prevention of new fracture. However, many pa...

journal_title：Aging clinical and experimental research

authors： Wang P,Li Y,Zhuang H,Yu H,Cai S,Xu H,Chen Z,Lin J,Yao X

更新日期：2019-10-01 00:00:00

abstract：:Falls in the elderly are very common and represent a serious cause of morbidity, severe disability and death. Impairments of the mechanisms of postural stability with age and the presence of acute and chronic diseases may favour the occurrence of falls in the elderly. Together with the adoption of non-pharmacological ...

journal_title：Aging clinical and experimental research

authors： Gatto S,Gimigliano F,Gimigliano R,Iolascon G

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Glycemic control in geriatric patients with type 2 diabetes (T2DM) remains clinically challenging. The objective of this study was to compare the safety and efficacy of insulin lispro in patients C65 years (geriatric) to those\65 years (non-geriatric), using a metaanalysis of randomized controlled c...

journal_title：Aging clinical and experimental research

authors： Curtis BH,Rees TM,Gaskins KA,Sierra-Johnson J,Liu R,Jiang HH,Holcombe JH

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Researchers and policy-makers have recognized that quality of life assessments are essential to better understand the benefits of rehabilitation intervention. The purpose of the study was to examine associations between functional status and satisfaction with community participation for persons with...

journal_title：Aging clinical and experimental research

authors： Ostir GV,Smith PM,Smith D,Ottenbacher KJ

更新日期：2005-02-01 00:00:00

abstract：PURPOSE:To evaluate (a) the performance in predicting the presence of bone fractures of trabecular bone score (TBS) and hip structural analysis (HSA) in type 2 diabetic postmenopausal women compared to a control group and (b) the fracture prediction ability of TBS versus Fracture Risk Calculator (FRAX®) as well as whet...

journal_title：Aging clinical and experimental research

authors： Bonaccorsi G,Fila E,Messina C,Maietti E,Ulivieri FM,Caudarella R,Greco P,Guglielmi G

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND AND AIMS:The effect of heavy work-related physical loads (WRPL) on low back pain (LBP) and impaired physical function has been studied extensively in active workers but not in pensioners. METHODS:We compared LBP and physical function in post-menopausal pensioners, divided according to their life-long WRPL i...

journal_title：Aging clinical and experimental research

authors： Gnudi S,Sitta E,Gnudi F,Pignotti E

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Changes in some rhythmometric parameters have been reported in the elderly as a consequence of both structural and neurochemical changes occurring in the central nervous system. Since alterations of lipid and lipoprotein metabolism are directly involved in several age-related disorders, the aim of t...

journal_title：Aging clinical and experimental research

authors： Trotti R,Rondanelli M,Cuzzoni G,Ferrari E,d'Eril GM

更新日期：2002-04-01 00:00:00

abstract：:The incidence of acetabular fractures in the elderly is recently becoming common. Acetabular fractures in this age range are more demanding, regarding fracture patterns, poor bone quality, patient status and potential comorbidities. Therefore it is necessary to determine the ideal treatment that should allow patients ...

journal_title：Aging clinical and experimental research

authors： D'Imporzano M,Liuni FM,Tarantino U

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Statins therapy in the secondary prevention of coronary artery disease (CAD) is associated with a lower risk of adverse cardiovascular events. However, little is known regarding the association of elderly patients with nutritional risk on statin therapy. AIMS:To investigate whether older patients with CAD w...

journal_title：Aging clinical and experimental research

authors： Huang BT,Huang FY,Pu XB,Xia TL,Peng Y,Chen F,Yang Y,Liao YB,Chen M

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Physical exercise and nutrition seem to have a key role in the management of hip fracture patients. AIM:To evaluate the impact of a 2-month rehabilitative protocol combined with dietetic counseling, with or without essential amino acid supplementation, on functioning in hip fracture patients. METHODS:In th...

journal_title：Aging clinical and experimental research

authors： Invernizzi M,de Sire A,D'Andrea F,Carrera D,Renò F,Migliaccio S,Iolascon G,Cisari C

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:In addition to the normal process of ageing, frailty, defined as a geriatric syndrome, is becoming more prevalent. Around 10% of people over 65 years and 25-50% of those aged over 85 years are frail. Frail elderly are more vulnerable to external stressors and have an increased risk of adverse health outcomes...

journal_title：Aging clinical and experimental research

authors： Windhaber T,Koula ML,Ntzani E,Velivasi A,Rizos E,Doumas MT,Pappas EE,Onder G,Vetrano DL,Roudriguez Laso A,Roudriguez Manjas L,Illario M,Roller-Wirnsberger RE,ADVANTAGE JA WP8 group.

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Functional brain imaging has shown that bilateral brain reorganization may occur after unilateral cerebral damage. The present study searched for evidence of bilateral motor control changes in gait in patients with chronic unilateral stroke. METHODS:Gait variables (temporal and spatial parameters, ...

journal_title：Aging clinical and experimental research

authors： Titianova EB,Peurala SH,Pitkänen K,Tarkka IM

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND AND AIMS:While caloric restriction (CR) is associated with a prolonged lifespan in multiple species by regulating metabolism, a comprehensive profile of metabolism under CR conditions remains largely unclear. Therefore, in this study we aimed to characterize the metabolomic profiling associated with CR using...

journal_title：Aging clinical and experimental research

authors： Zhang Y,Yan S,Gao X,Xiong X,Dai W,Liu X,Li L,Zhang W,Mei C

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Osteoporosis is a common disease in elderly, characterized by poor bone quality as a result of alterations affecting trabecular bone. However, recent studies have described also an important role of alterations of cortical bone in the physiopathology of osteoporosis. Although dual-energy X-ray absorptiometry...

journal_title：Aging clinical and experimental research

authors： Feola M,Rao C,Tempesta V,Gasbarra E,Tarantino U

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:To investigate the feasibility and significance of the clinical application of ultrasound score in assessing the clinical severity of acute cholecystitis in the elderly. METHODS:Pre-surgery ultrasonography was performed on 72 elderly patients with acute cholecystitis who were scheduled for cholecystectomy to...

journal_title：Aging clinical and experimental research

authors： Zhang L,Han Q,Zhang H,Li D,Yao K

更新日期：2015-02-01 00:00:00

abstract：PURPOSE:The diagnostic value of the neutrophil-to-lymphocyte count ratio (NLR) and the Appendicitis Inflammatory Response (AIR) score for identifying acute appendicitis (AA) perforation in elderly patients in the emergency department (ED) were evaluated. METHODS:A total of 103 patients who were admitted for appendecto...

journal_title：Aging clinical and experimental research

authors： Jung SK,Rhee DY,Lee WJ,Woo SH,Seol SH,Kim DH,Choi SP

更新日期：2017-06-01 00:00:00

abstract：:We describe a family composed of six siblings, four of which affected by late-onset Alzheimer's disease (LOAD). We constructed the family pedigree, evaluated mutations usually associated with early-onset Alzheimer's disease (APP, PSEN1, PSEN2), and assessed polymorphisms in the apolipoprotein E (APOE) gene and in cyto...

journal_title：Aging clinical and experimental research

authors： Abbate C,Arosio B,Cantatore A,Viti N,Giunco F,Bagarolo R,Nicolini P,Gussago C,Ferri E,Casati M,Rossi PD,Casè A,Bergamaschini L,Vergani C,Mari D

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Age-related reductions in strength and power are considered to negatively impact balance control, but the existence of a direct association is still an issue of debate. This is possibly due to the fact that balance assessment is complex, reflects different underlying physiologic mechanisms and invol...

journal_title：Aging clinical and experimental research

authors： Forte R,Boreham CA,De Vito G,Ditroilo M,Pesce C

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND AIMS:The aim of this study was to develop a Turkish version of the Nottingham Extended Activities of Daily Living Scale (NEADLS) and to assess its reliability and validity. METHODS:Sixty healthy volunteers over 67 years old were included in the study. After translation, the Turkish version of the scale ...

journal_title：Aging clinical and experimental research

authors： Sahin F,Yilmaz F,Ozmaden A,Kotevoglu N,Sahin T,Kuran B

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Falls among the elderly are often associated with walking on uneven ground. Obstacle negotiation requires both postural reaction strategies and anticipatory strategies which may be impaired with age. Anticipatory strategies are necessary in many daily living situations such as crossing the street and negotia...

journal_title：Aging clinical and experimental research

authors： Laessoe U,Voigt M

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Hip fractures (HF) are a major issue worldwide. We aimed at evaluating the practices in delivering care to patients with HF among several Italian Orthogeriatric centers. METHODS:The study took place from February 2016 to July 2018. Seven performance indicators (pre-surgical cognitive assessment, surgery per...

journal_title：Aging clinical and experimental research

authors： Ferrara MC,Andreano A,Tassistro E,Rapazzini P,Zurlo A,Volpato S,Mussi C,Corsi M,Lunardelli ML,Martini E,Castoldi G,De Filippi F,Pizzonia M,Monacelli F,Barone A,Pilotto A,March A,Ungar A,Capelli R,Galmarini V,Franz

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND AND AIMS:In Italy there is a paucity of empirical data on practices concerning end-of-life decisions (ELDs) in geriatrics. We aimed to investigate the frequency and characteristics of ELDs made by Italian physicians and nurses in the geriatric setting. METHODS:In 2009, an anonymous questionnaire was sent to...

journal_title：Aging clinical and experimental research

authors： Giantin V,Siviero P,Simonato M,Iasevoli M,Pengo V,Andrigo M,Storti M,Valentini E,Pegoraro R,Maggi S,Crepaldi G,Manzato E

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Cardiovascular disease is a major cause of mortality in end-stage renal disease patients (ESRD). The rate of elderly and polypathologic patients in ESRD is increasing. Elevated levels of C-reactive protein (CRP) have been shown to be associated with increased mortality in ESRD patients. The aim of t...

journal_title：Aging clinical and experimental research

authors： Millet C,Bosson JL,Pernod G,Wauters JP,Couturier P,Quesada JL,Zaoui P

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Although the role of afferent input from cervical muscles on the control of posture and locomotion is recognised, it is surprising that there is an absence of data reporting whether joint position sense at the cervical level is impaired in older healthy adults. The present experiment was designed to...

journal_title：Aging clinical and experimental research

authors： Vuillerme N,Pinsault N,Bouvier B

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Marital and parental role characteristics are important factors in both men and women's health. Most studies to date have either focused on disease specific outcomes or summary measures of self-reported health rather than using functional tests of performance. The goal of this study is to investigat...

journal_title：Aging clinical and experimental research

authors： Guralnik JM,Butterworth S,Patel K,Mishra G,Kuh D

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Nursing home residents constitute a frail, multi-diseased and heterogeneous group. As physical activity is essential for the preservation of function, personalized training and activities are of great importance. The main objective of this study was to describe the influence of an individually tailo...

journal_title：Aging clinical and experimental research

authors： Frändin K,Borell L,Grönstedt H,Bergland A,Helbostad JL,Puggaard L,Andresen M,Granbo R,Hellström K

更新日期：2009-08-01 00:00:00

abstract：:Physical frailty (PF) and sarcopenia are major health issues in geriatric populations, given their high prevalence and association with several adverse outcomes. Nevertheless, the lack of an univocal operational definition for the two conditions has so far hampered their clinical implementation. Existing definitional ...

journal_title：Aging clinical and experimental research

authors： Calvani R,Marini F,Cesari M,Tosato M,Picca A,Anker SD,von Haehling S,Miller RR,Bernabei R,Landi F,Marzetti E,SPRINTT Consortium.

更新日期：2017-02-01 00:00:00

abstract：:Visual identification of vertebral fractures from spinal radiographs makes use of operator expertise in ruling out non-fracture deformities or normal variants. Morphometric X-ray absorptiometry (MXA) has recently been developed to assess vertebral deformity status quantitatively by dual energy X-ray absorptiometry (DX...

journal_title：Aging clinical and experimental research

authors： Francucci CM,Romagni P,Fiscaletti P,Caudarella R,Boscaro M

更新日期：2007-06-01 00:00:00