The Charlson Comorbidity and Barthel Index predict length of hospital stay, mortality, cardiovascular mortality and rehospitalization in unselected older patients admitted to the emergency department.

Abstract:

BACKGROUND AND AIMS:The Charlson Comorbidity Index (CCI) is the most widely used assessment tool to report the presence of comorbid conditions. The Barthel index (BI) is used to measure performance in activities of daily living. We prospectively investigated the performance of CCI or BI to predict length of hospital stay (LOS), mortality, cardiovascular (CV) mortality and rehospitalization in unselected older patients on admission to the emergency department (ED). We also studied the association of CCI or BI with costs. METHODS:We consecutively enrolled 307 non-surgical patients ≥ 68 years presenting to the ED with a wide range of comorbid conditions. Baseline characteristic, clinical presentation, laboratory data, echocardiographic parameters and hospital costs were compared among patients. All patients were followed up for mortality, CV mortality and rehospitalization within the following 12 months. A multivariate analysis was performed. RESULTS:Mortality was increased for patients having a higher CCI or BI with a hazard ratio around 1.17-1.26 or 0.75-0.81 (obtained for different models) for one or ten point increase in CCI or BI, respectively. The prognostic impact of a high CCI or BI on CV mortality and rehospitalization was also significant. In a multiple linear regression using the same independent variables, CCI and BI were identified as a predictor of LOS in days. Multiple linear regression analysis did not confirm an association between CCI and costs, but for BI after adjusting for multiple factors. CONCLUSION:CCI and BI independently predict LOS, mortality, CV mortality, and rehospitalization in unselected older patients admitted to ED.

journal_name

Aging Clin Exp Res

authors

Bahrmann A,Benner L,Christ M,Bertsch T,Sieber CC,Katus H,Bahrmann P

doi

10.1007/s40520-018-1067-x

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

1233-1242

issue

9

eissn

1594-0667

issn

1720-8319

pii

10.1007/s40520-018-1067-x

journal_volume

31

pub_type

杂志文章
  • Acetabular fragility fractures in elderly patients.

    abstract::The incidence of acetabular fractures in the elderly is recently becoming common. Acetabular fractures in this age range are more demanding, regarding fracture patterns, poor bone quality, patient status and potential comorbidities. Therefore it is necessary to determine the ideal treatment that should allow patients ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,评审

    doi:

    authors: D'Imporzano M,Liuni FM,Tarantino U

    更新日期:2011-04-01 00:00:00

  • Diabetes in a geriatric ward: efficacy and safety of new insulin analogs in very old inpatients.

    abstract:AIMS:1) to evaluate the prevalence of diabetes mellitus (DM) in a geriatric ward; 2) to assess the efficacy and safety of insulin analogs in elderly inpatients over 65 years of age. METHODS:We analysed the medical records of 1851 elderly inpatients admitted to our geriatric clinic from March 2009 to September 2011, to...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:

    authors: Franchin A,Corradin ML,Giantin V,Rossi F,Zanatta F,Attanasio F,Toffanello ED,Manzato E

    更新日期:2012-06-01 00:00:00

  • The effect of short-term health promotion intervention on motor function in community-dwelling older adults.

    abstract:BACKGROUND:Slow walking speed as one indicator of physical frailty has been found to be associated with deterioration of the health status. Although many reports have shown that exercise training improves motor function, it is unclear whether a group-based and short-term health promotion intervention will improve motor...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-018-0994-x

    authors: Kutsuna T,Hiyama Y,Kusaka S,Kusumoto Y,Tsuchiya J,Umeda M,Takahashi T

    更新日期:2019-04-01 00:00:00

  • Stepping down backwards as a means of detecting biomechanical differences between healthy older and younger adults.

    abstract:BACKGROUND AND AIMS:Changes in sensory- motor systems that occur with age result in a decrease in postural equilibrium, which has been linked with an increased risk of falling in the elderly. Stepping down backwards from a step perturbs dynamic postural equilibrium, thus offering an opportunity to analyze the biomechan...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/BF03324776

    authors: Michel-Pellegrino V,Hewson D,Hogrel JY,Duchêne J

    更新日期:2008-06-01 00:00:00

  • Unmet needs and research challenges for late-life mood disorders.

    abstract::Mood disorders are common and often under-recognised in older people whereby, together with the general ageing of the population, they are becoming a significant and growing public health problem worldwide. However, the need to address the problem of late life mood disorders in a real-world setting is met with a surpr...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,评审

    doi:10.1007/s40520-013-0149-z

    authors: Ghio L,Vaggi M,Amore M,Ferrannini L,Natta W

    更新日期:2014-04-01 00:00:00

  • Diagnostic and treatment practices of delirium in a general hospital.

    abstract:BACKGROUND:Despite the increase in research on delirium, it remains underdiagnosed and difficult to manage, and the outcome is poor especially in older people. AIMS:To identify the clinically diagnosed rates of delirium, the possible aetiologies, to describe treatment, number and type of psychotropic medication used a...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-014-0227-x

    authors: Rooney S,Qadir M,Adamis D,McCarthy G

    更新日期:2014-12-01 00:00:00

  • Evaluation of renal function in the elderly, not as easy as it seems: a review.

    abstract::In the elderly assessment of renal function by glomerular filtration rate estimation is crucial for diagnostic, therapeutic and prognostic purposes. Our aim is to illustrate the different formulas available and their respective advantages and disadvantages. ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,评审

    doi:10.1007/s40520-014-0311-2

    authors: Ungar A,Iacomelli I,Giordano A,Roberts AT,Rafanelli M,Marchionni N

    更新日期:2015-08-01 00:00:00

  • The association between sociodemographic characteristics and dementia in patients with atrial fibrillation.

    abstract:OBJECTIVES:Association between socio-demographic factors and dementia risk is studied in general but not for atrial fibrillation (AF) patients. METHODS:We studied AF patients ≥ 45 years in Sweden 1998-2012 (n = 537,513) using the Total Population Register for socio-demographic factors, the Swedish Cause of Death Regis...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-019-01449-3

    authors: Wändell P,Carlsson AC,Li X,Gasevic D,Sundquist J,Sundquist K

    更新日期:2020-11-01 00:00:00

  • The effect of milk consumption on bone and fracture incidence, an update.

    abstract::Milk is a major source of high bioavailable calcium in most developed countries with an average calcium content of 1150 mg/L, providing a ready means of meeting the daily requirements. Its content in other minerals, phosphorus, vitamins, iodine, proteins, potassium and various nutrients is supposed to be beneficial fo...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,评审

    doi:10.1007/s40520-019-01192-9

    authors: Fardellone P

    更新日期:2019-06-01 00:00:00

  • Physical activity among hospitalised older people: insights from upper and lower limb accelerometry.

    abstract:BACKGROUND:Few studies have explored the activity levels of hospitalised older people and the intra-daily activity patterns in this group have not been described. AIMS:To describe the quantity and daily pattern of physical activity among hospitalised older people using two accelerometers: the ankle-worn StepWatch Acti...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-018-0930-0

    authors: Lim SER,Dodds R,Bacon D,Sayer AA,Roberts HC

    更新日期:2018-11-01 00:00:00

  • Morphometric dual-energy X-ray absorptiometry (MXA) for identification of vertebral fractures.

    abstract::Visual identification of vertebral fractures from spinal radiographs makes use of operator expertise in ruling out non-fracture deformities or normal variants. Morphometric X-ray absorptiometry (MXA) has recently been developed to assess vertebral deformity status quantitatively by dual energy X-ray absorptiometry (DX...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,评审

    doi:

    authors: Francucci CM,Romagni P,Fiscaletti P,Caudarella R,Boscaro M

    更新日期:2007-06-01 00:00:00

  • Clinical assessment of gait and functional mobility in Italian healthy and cognitively impaired older persons using wearable inertial sensors.

    abstract:AIM:The main purpose of the present study was to verify the feasibility of wearable inertial sensors (IMUs) in a clinical setting to screen gait and functional mobility in Italian older persons. In particular, we intended to verify the capability of IMUs to discriminate individuals with and without cognitive impairment...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-020-01715-9

    authors: Mulas I,Putzu V,Asoni G,Viale D,Mameli I,Pau M

    更新日期:2020-09-25 00:00:00

  • Aging leads to dysfunctional innate immune responses to TLR2 and TLR4 agonists.

    abstract:BACKGROUND:Sepsis is more common in the elderly. TNF⍺ is recognized as an important mediator in sepsis and Toll-like receptors (TLRs) play an important role in initiating signaling cascades to produce TNF⍺. Little is known about how innate immunity is altered in healthy human aging that predisposes to sepsis. AIMS AND...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-018-1064-0

    authors: Bailey KL,Smith LM,Heires AJ,Katafiasz DM,Romberger DJ,LeVan TD

    更新日期:2019-09-01 00:00:00

  • A combined stepping and visual tracking task predicts cognitive decline in older adults better than gait or visual tracking tasks alone: a prospective study.

    abstract:BACKGROUND:It is unclear whether motor-cognitive dual tasks predict cognitive decline better than either motor or cognitive tasks alone. AIMS:To examine the utility of the novel motor-cognitive dual-task test [Stepping Trail Making Test (S-TMT)], as a predictor of cognitive decline, and compare its predictive performa...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-020-01714-w

    authors: Osuka Y,Kim H,Watanabe Y,Taniguchi Y,Kojima N,Seino S,Kawai H,Sakurai R,Inagaki H,Awata S,Shinkai S

    更新日期:2020-09-23 00:00:00

  • Swallowing dysfunction as risk factor for undernutrition in older people admitted to Swedish short-term care: a cross-sectional study.

    abstract:BACKGROUND:Swallowing dysfunction and risk of undernutrition increase the risk of pneumonia, morbidity, and mortality. Short-term care is an unexplored care context, where many older people stay yearly. AIM:This cross-sectional study aimed to describe and analyze the relationship between swallowing dysfunction and ris...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s40520-018-0944-7

    authors: Hägglund P,Fält A,Hägg M,Wester P,Levring Jäghagen E

    更新日期:2019-01-01 00:00:00

  • Voluntary exercise and mild food restriction effectively retard the collagen biomarker of aging.

    abstract:BACKGROUND AND AIMS:Obesity and lack of physical exercise characterize increasing numbers of people in Western societies, resulting in increasing morbidity and mortality. Regular physical exercise, on the other hand, has been shown to be beneficial. Beneficial effects have also been shown in laboratory rodent studies--...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/BF03327370

    authors: Viidik A,Skalicky M

    更新日期:2003-12-01 00:00:00

  • Improved health among 70-year olds: comparison of health indicators in three different birth cohorts.

    abstract:BACKGROUND AND AIMS:Whether or not there has been a "compression of morbidity" in older ages has been vividly debated during the last decades. Previous studies have found indications of both improved and deteriorated health among elderly persons. Few studies have analyzed how changes in health indicators are influenced...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/BF03324463

    authors: Wilhelmson K,Allebeck P,Steen B

    更新日期:2002-10-01 00:00:00

  • Neutrophil-to-lymphocyte count ratio is associated with perforated appendicitis in elderly patients of emergency department.

    abstract:PURPOSE:The diagnostic value of the neutrophil-to-lymphocyte count ratio (NLR) and the Appendicitis Inflammatory Response (AIR) score for identifying acute appendicitis (AA) perforation in elderly patients in the emergency department (ED) were evaluated. METHODS:A total of 103 patients who were admitted for appendecto...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-016-0584-8

    authors: Jung SK,Rhee DY,Lee WJ,Woo SH,Seol SH,Kim DH,Choi SP

    更新日期:2017-06-01 00:00:00

  • Total lymphocyte count and in-hospital mortality in older persons with multimorbidity.

    abstract:BACKGROUND AND AIMS:Low total lymphocyte count (TLC) has been found to be a poor prognostic factor in adults affected by heart diseases, malignancy, and renal failure. The aims of this study were to verify if a low TLC was associated with in-hospital mortality in older persons and to evaluate whether this association w...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/BF03324858

    authors: Marengoni A,Petroboni B,Casella S,Martinelli D,Cossi S

    更新日期:2008-08-01 00:00:00

  • Effect of age on treatment, trends and outcome of patients hospitalized with atrial fibrillation: insights from a 20-years registry in a Middle-Eastern country (1991-2010).

    abstract:BACKGROUND:Most studies on atrial fibrillation (AF) epidemiology, treatment, and outcomes have included mainly Caucasians patients. The world literature on AF in other ethnicities is very limited particularly in the elderly. AIMS:The aim of this study was to compare the clinical characteristics, treatment and outcome ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.3275/8757

    authors: Salam AM,AlBinali HA,Al-Sulaiti EM,Al-Mulla AW,Singh R,Al Suwaidi J

    更新日期:2012-12-01 00:00:00

  • Calcium channel blockers and stroke.

    abstract::The most frequent indication for Calcium Channel Blockers (CCBs) is their use as antihypertensive agents for primary or secondary stroke prevention. Hypertension contributes to virtually all mechanisms of stroke, of atherothrombotic, lacunar, cardioembolic and intraparenchymal hemorrhage types. In comparison with the ...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,评审

    doi:

    authors: Inzitari D,Poggesi A

    更新日期:2005-08-01 00:00:00

  • Production of nitric oxide, lipid peroxidation and oxidase activity of ceruloplasmin in blood of elderly patients with primary hypertension. Effects of perindopril treatment.

    abstract:BACKGROUND AND AIMS:One of the factors playing a role in both the aging process and the etiopathogenesis of primary hypertension is oxidative stress. The purpose of this work was to estimate the production of nitric oxide (NO), oxidase activity of ceruloplasmin (Cp) and level of malondialdehyde (MDA), the end-product o...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/BF03324634

    authors: Kedziora-Kornatowska K,Kornatowski T,Bartosz G,Pawluk H,Czuczejko J,Kedziora J,Szadujkis-Szadurski L

    更新日期:2006-02-01 00:00:00

  • Organ and tissue-dependent effect of resveratrol and exercise on antioxidant defenses of old mice.

    abstract:BACKGROUND:Oxidative stress has been considered one of the causes of aging. For this reason, treatments based on antioxidants or those capable of increasing endogenous antioxidant activity have been taken into consideration to delay aging or age-related disease progression. AIM:In this paper, we determine if resveratr...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-015-0366-8

    authors: Tung BT,Rodriguez-Bies E,Thanh HN,Le-Thi-Thu H,Navas P,Sanchez VM,López-Lluch G

    更新日期:2015-12-01 00:00:00

  • Effects of denosumab on cortical and trabecular microarchitecture: evidences from clinical studies.

    abstract::Excess of bone remodeling is still the major pathogenic factor in involutional osteoporosis. This phenomenon is linked to an imbalance between neoformation (by osteoblasts) and resorption (by osteoclasts). Recently, research in drug development is focused on new and more "physiological" approach to balance bone remode...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,评审

    doi:10.1007/s40520-013-0086-x

    authors: Iolascon G,Resmini G,Tarantino U

    更新日期:2013-10-01 00:00:00

  • Depressed mood: changes during a five-year follow-up in 75-year-old men and women in three Nordic localities.

    abstract::The aim of the study was to look firstly at the changes that occurred in depressive symptomatology over a 5-year period among originally 75-year-old residents in three Nordic localities: Glostrup in Denmark, Göteborg in Sweden and Jyväskylä in Finland, and secondly, at some selected variables if they predicted depress...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:

    authors: Heikkinen RL,Berg S,Avlund K,Tömäkangas T

    更新日期:2002-06-01 00:00:00

  • Left ventricular hypertrophy and blood pressure as predictors of cognitive decline in old age.

    abstract:BACKGROUND AND AIMS:The relationships between blood pressure (BP) and cognition are complex and are still partly unclear. The impact of history of hypertension, present BP levels, and left ventricular hypertrophy (LVH) on cognition was investigated in a 10-year follow-up study of an aged population. METHODS:The popula...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/BF03324544

    authors: Kähönen-Väre M,Brunni-Hakala S,Lindroos M,Pitkala K,Strandberg T,Tilvis R

    更新日期:2004-04-01 00:00:00

  • Feasibility of a machine vs free weight strength training program and its effects on physical performance in nursing home residents: a pilot study.

    abstract:BACKGROUND:Resistance training holds promise for nursing home residents to prevent further disabilities, falls, and fractures. Free weight as well as machine training may offer an efficient option to improve physical performance, but the feasibility of these training regimes among elderly who require continuous institu...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s40520-017-0830-8

    authors: Johnen B,Schott N

    更新日期:2018-07-01 00:00:00

  • The effect of individualized, theory-based counselling intervention on active aging and quality of life among older people (the AGNES intervention study).

    abstract:BACKGROUND:We define active aging as a striving for activities as per one's goals, capacities and opportunities. AIM:To test the 1-year counselling intervention effects on active aging. METHODS:In this two-arm single-blinded randomized controlled trial, the intervention group received individually tailored counsellin...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-020-01535-x

    authors: Rantanen T,Hassandra M,Pynnönen K,Siltanen S,Kokko K,Karavirta L,Kauppinen M,Sipilä S,Saajanaho M,Portegijs E

    更新日期:2020-10-01 00:00:00

  • The effect of different test protocols and walking distances on gait speed in older persons.

    abstract:BACKGROUND AND AIMS:Walking is the core physical activity of older persons. The assessment of walking capacity is increasingly important for clinical purposes and clinical research. Differences between assessment tools and protocols for short walks to obtain gait characteristics can be responsible for changes, e.g., in...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-020-01703-z

    authors: Krumpoch S,Lindemann U,Rappl A,Becker C,Sieber CC,Freiberger E

    更新日期:2020-09-15 00:00:00

  • Serum sestrins: potential predictive molecule in human sarcopenia.

    abstract:BACKGROUND:The aging trajectory from a state of robustness and good health proceeds from sarcopenia to frailty followed by disability and death due to decline in skeletal muscle mass and function. Sarcopenia is now formally recognized as a muscle disease with an ICD-10-MC diagnosis code. The autophagic response seems t...

    journal_title:Aging clinical and experimental research

    pub_type: 杂志文章

    doi:10.1007/s40520-020-01642-9

    authors: Rajan SP,Anwar M,Jain B,Khan MA,Dey S,Dey AB

    更新日期:2020-06-27 00:00:00