Abstract：
BACKGROUND AND AIMS:Monochromatic pulsating light may have effects on wound healing. In an earlier study of grade II ulcers, there was a tendency toward better healing in the phototherapy group (p=0.06). The present study on patients with grade II ulcers was performed to verify these findings. Data from this study were pooled with data from the earlier study. METHODS:Ninety-four patients were offered participation in the new study and 76 patients were evaluated. They were pooled with 87 patients from the earlier study, bringing the total to 163. All patients were treated with monochromatic pulsating light or placebo over the ulcerated area, according to a specified program up to 12 weeks. RESULTS:The mean normalized reduction in pressure ulcer size at week 12 was 0.79 for the phototherapy group and 0.50 for the placebo group (95% confidence interval 0.01-0.53; p=0.039). No serious side-effects were noted. CONCLUSIONS:Monochromatic pulsating light accelerates healing in grade II pressure ulcers in elderly patients.
journal_name
Aging Clin Exp Resjournal_title
Aging clinical and experimental researchauthors
Dehlin O,Elmståhl S,Gottrup Fdoi
10.1007/BF03324734subject
Has Abstractpub_date
2007-12-01 00:00:00pages
478-83issue
6eissn
1594-0667issn
1720-8319pii
4282journal_volume
19pub_type
杂志文章,随机对照试验abstract：BACKGROUND AND AIMS:Low total lymphocyte count (TLC) has been found to be a poor prognostic factor in adults affected by heart diseases, malignancy, and renal failure. The aims of this study were to verify if a low TLC was associated with in-hospital mortality in older persons and to evaluate whether this association w...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324858
更新日期：2008-08-01 00:00:00
abstract：:Senescence of the brain seems to be related to increased levels of free oxygen radical (FOR). FOR may damage macromolecular compounds such as: proteins, lipids, and DNA. In the aging brain, increased FOR levels damage DNA, mitochondrial DNA (mtDNA), and nuclear DNA (nDNA). In DNA they damage single and double strands,...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/s40520-013-0004-2
更新日期：2013-04-01 00:00:00
abstract：BACKGROUND AND AIMS:The effect of heavy work-related physical loads (WRPL) on low back pain (LBP) and impaired physical function has been studied extensively in active workers but not in pensioners. METHODS:We compared LBP and physical function in post-menopausal pensioners, divided according to their life-long WRPL i...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324899
更新日期：2009-02-01 00:00:00
abstract：AIM:The main purpose of the present study was to verify the feasibility of wearable inertial sensors (IMUs) in a clinical setting to screen gait and functional mobility in Italian older persons. In particular, we intended to verify the capability of IMUs to discriminate individuals with and without cognitive impairment...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-020-01715-9
更新日期：2020-09-25 00:00:00
abstract：BACKGROUND AND AIMS:Acetylcholinesterase inhibitor (AChEis) therapy in Alzheimer Disease (AD) has been shown to provide cognitive benefits and to slow progression of the disease. AChEis have also been demonstrated to improve behavioral symptoms, although there seem to be subtle differences in the magnitude of response....
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324693
更新日期：2007-06-01 00:00:00
abstract：:Epidemiological studies of suicide in the elderly indicate that, in the last few decades, there has been a relevant increase in suicide rates in old age in a number of Asian and Latin nations, with an almost parallel decrease in Anglo-Saxon counties. Mental disorders, particularly depression, physical illness, persona...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/BF03324486
更新日期：2003-04-01 00:00:00
abstract：:The aim of the study was to look firstly at the changes that occurred in depressive symptomatology over a 5-year period among originally 75-year-old residents in three Nordic localities: Glostrup in Denmark, Göteborg in Sweden and Jyväskylä in Finland, and secondly, at some selected variables if they predicted depress...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：
更新日期：2002-06-01 00:00:00
abstract：BACKGROUND:Frailty assessment has acquired an increasing importance in recent years and it has been demonstrated that this vulnerable profile predisposes elderly patients to a worse outcome after surgery. Therefore, it becomes paramount to perform an accurate stratification of surgical risk in elderly undergoing emerge...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-020-01735-5
更新日期：2020-11-18 00:00:00
abstract：BACKGROUND AND AIMS:Muscle strength may decline with age differentially in the upper and lower limbs. This information is difficult to capture through a single measure. The present study therefore aimed to characterize the relative changes in handgrip and lower limb muscle strength with aging by expressing them as a ra...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03325252
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND AND AIMS:With an increasing population aged 85 years and over, the aim of this study was to describe health status and living conditions in the oldest old and to estimate age and sex differences in a Northern European population. METHODS:A population-based cross-sectional study, The Umeå 85+ Study, was carr...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03327426
更新日期：2006-04-01 00:00:00
abstract：:Uncountable health care organizations, clinicians, and individuals are striving to prevent obesity and the many chronic medical conditions linked to it by advocating a healthy lifestyle that includes measures such as reducing dietary calorie intake (i.e., calorie restriction = CR and intermittent fasting = IF) or limi...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/s40520-019-01174-x
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:Attitude of healthcare providers toward older people is very important in the aging world. Neurologists contact older adults very frequently. We aimed to investigate the attitudes of neurologists toward older adults. MEASUREMENTS:We recorded participants age; sex; duration of clinical practice in neurology; ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-016-0606-6
更新日期：2017-08-01 00:00:00
abstract：:The aim of this study was to assess the effectiveness of balance training with somatosensory and neurofeedback training on dynamic and static balance in healthy, elderly adults. The sample group consisted of 45 healthy adults randomly assigned to one of the three test groups: somatosensory, neurofeedback, and a contro...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s40520-017-0835-3
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:Postoperative cognitive dysfunction (POCD) is a common complication after orthopedic surgery, which is not conducive to the prognosis of the elderly. AIMS:We performed this study to investigate the effects of oxycodone applied for patient-controlled intravenous analgesia (PCIA) on postoperative cognitive fu...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s40520-019-01202-w
更新日期：2020-02-01 00:00:00
abstract：:We present a 61-year-old man with marked peripheral blood eosinophilia, feature of hypereosinophilic syndrome, that later evolved into acute lymphocytic leukemia (ALL-L2). Initially the patient suffered from significant complications related to eosinophilic toxicity, including large urticarial hyperpigmented plaques, ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.3275/8337
更新日期：2012-10-01 00:00:00
abstract：:Visual identification of vertebral fractures from spinal radiographs makes use of operator expertise in ruling out non-fracture deformities or normal variants. Morphometric X-ray absorptiometry (MXA) has recently been developed to assess vertebral deformity status quantitatively by dual energy X-ray absorptiometry (DX...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：
更新日期：2007-06-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to evaluate the relationships between the serum levels of adiponectin (ADP) and matrix metalloproteinase-9 (MMP-9) and postoperative cognitive dysfunction (POCD) in elderly patients after general anesthesia. METHODS:The cognitive functions of 98 elderly patients who were scheduled t...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-015-0519-9
更新日期：2016-12-01 00:00:00
abstract：OBJECTIVES:The circadian rhythm of serum thyroid stimulating hormone (TSH) levels in patients with Alzheimer's disease was measured by means of a case-control study. METHODS:Serum samples from cases and controls were collected continuously for 2 days, and then once every 2 h (even number time-point during the first da...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-013-0025-x
更新日期：2013-05-01 00:00:00
abstract：:Neuroinflammation and cholinergic dysfunction, leading to cognitive impairment, are hallmarks of aging and neurodegenerative disorders, including Alzheimer's disease (AD). Acetylcholinesterase inhibitors (AChEI), the symptomatic therapy in AD, attenuate and delay the cognitive deficit by enhancing cholinergic synapses...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/s40520-019-01359-4
更新日期：2019-10-03 00:00:00
abstract：:Most visual and cognitive functions are affected by aging over the lifespan. In this study, our aim was to investigate the loss in sensitivity to different classes of second-order stimuli-a class of stimuli supposed to be mainly processed in extrastriate cortex-in the aging population. These stimuli will then allow on...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-018-1018-6
更新日期：2019-05-01 00:00:00
abstract：:Osteoporosis can significantly impact on the risk of developing a fracture. Thus, fragility fractures represent a challenge for health professionals and decision makers of the twenty-first century. The aim of this work is to review the literature concerning osteoporotic fractures in Italy in terms of incidence, rate o...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/s40520-013-0071-4
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND AND AIM:Several measurements were taken for frailty classification in geriatric population. "Frailty index" is based on "deficits in health," but it is still not available in Italian version. Thus, the aim of the present work was to validate a version of "frailty index" for the Italian geriatric community. ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-017-0793-9
更新日期：2017-10-01 00:00:00
abstract：BACKGROUND AND AIMS:Walking is the core physical activity of older persons. The assessment of walking capacity is increasingly important for clinical purposes and clinical research. Differences between assessment tools and protocols for short walks to obtain gait characteristics can be responsible for changes, e.g., in...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-020-01703-z
更新日期：2020-09-15 00:00:00
abstract：BACKGROUND AND AIMS:Researchers and policy-makers have recognized that quality of life assessments are essential to better understand the benefits of rehabilitation intervention. The purpose of the study was to examine associations between functional status and satisfaction with community participation for persons with...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03337718
更新日期：2005-02-01 00:00:00
abstract：BACKGROUND AND AIMS:There is no conclusive evidence that hospital fall prevention programs can reduce the number of falls. We aimed to investigate the effect of a targeted individualized falls prevention program in a geriatric rehabilitation hospital. METHODS:This was a two-stage cluster-controlled trial carried out i...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s40520-015-0330-7
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:Asymmetric vestibular function, decreased plantar sensation, postural control and functional ability have been associated with fall-related wrist fractures. OBJECTIVE:To investigate whether multi-sensory training (MST) improves postural control, vestibular function, foot sensation and functional ability amo...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s40520-019-01143-4
更新日期：2020-01-01 00:00:00
abstract：BACKGROUNDS:Different and new approaches have been proposed to prevent the risk of falling of elderly people, particularly women. AIMS:This study investigates the possibility that a new protocol based on the focal mechanical muscle vibration may reduce the risk of falling of elderly women. METHODS:A pragmatic randomi...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s40520-015-0356-x
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND:Cognitive impairment is common among stroke survivors. However, there is controversy on the role of the stroke itself or the associated subcortical damage in post-stroke cognitive decline. AIM:To assess the independent contribution and the interaction of age, the stroke itself and diffuse subcortical damage...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-015-0331-6
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND AND AIMS:An accurate diagnosis of sarcopenia is required. The aim of this study is to correlate the results of two methods to define sarcopenia using cross sectional body composition data, with actual loss of fat free mass. METHODS:Healthy older subjects (926 females and 381 males aged 70 years or more) and...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324705
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND AND AIMS:Proximal femoral fracture is often associated with long-term residual disability. Quadriceps weakness may be a factor in poor outcome. This study aimed to determine whether training of the quadriceps using electrical stimulation (ES) increases leg extensor power and decreases disability in elderly s...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,随机对照试验
doi：10.1007/BF03324749
更新日期：2008-02-01 00:00:00
