Improved health among 70-year olds: comparison of health indicators in three different birth cohorts.

abstract：BACKGROUND AND AIMS:To evaluate the effect of interdisciplinary outpatient geriatrics on the use, cost, and quality of health services in a fee-for-service (FFS) environment of two networks of primary care clinics operated by a not-for-profit provider organization in Dallas County, Texas. METHODS:The Senior Health Net...

journal_title：Aging clinical and experimental research

authors： Famadas JC,Frick KD,Haydar ZR,Nicewander D,Ballard D,Boult C

更新日期：2008-12-01 00:00:00

abstract：:We present a 61-year-old man with marked peripheral blood eosinophilia, feature of hypereosinophilic syndrome, that later evolved into acute lymphocytic leukemia (ALL-L2). Initially the patient suffered from significant complications related to eosinophilic toxicity, including large urticarial hyperpigmented plaques, ...

journal_title：Aging clinical and experimental research

authors： Song G,Liu H,Sun F,Gu L,Wang S

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) and type 2 diabetes, two diseases that contribute considerable morbidity and mortality in middle-age and elderly people, coexist and progress in parallel, leading to the presumption that one may cause the other. However, a causative link has not yet been established. METHODS:This st...

journal_title：Aging clinical and experimental research

authors： James D,Kang S,Park S

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Gait disorders are common in the elderly populations, and their prevalence increases with age. Abnormal gait has been associated with greater risk for adverse outcomes in older adults, such as immobility and falls, which in turn lead to loss of functional independence and death. AIM:The purpose of this revi...

journal_title：Aging clinical and experimental research

authors： Aboutorabi A,Arazpour M,Bahramizadeh M,Hutchins SW,Fadayevatan R

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:We define active aging as a striving for activities as per one's goals, capacities and opportunities. AIM:To test the 1-year counselling intervention effects on active aging. METHODS:In this two-arm single-blinded randomized controlled trial, the intervention group received individually tailored counsellin...

journal_title：Aging clinical and experimental research

authors： Rantanen T,Hassandra M,Pynnönen K,Siltanen S,Kokko K,Karavirta L,Kauppinen M,Sipilä S,Saajanaho M,Portegijs E

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:Patient navigation improves outcomes in various clinical contexts, but has not been evaluated in secondary fracture prevention. METHODS:We retrospectively reviewed charts of patients, age 50 + from April to October, 2016 hospitalized with fragility fracture contacted by a patient navigator. Patients were ...

journal_title：Aging clinical and experimental research

authors： Jia KQ,Southerland L,Phieffer L,Stephens JA,Ing SW

更新日期：2020-12-01 00:00:00

abstract：AIMS:The objective of this study was to examine baseline frailty status (including cognitive deficits) and important clinical outcomes, to inform shared decision-making in older adults receiving transcatheter aortic valve implantation (TAVI). METHODS AND RESULTS:We conducted a prospective, observational study of 82 TA...

journal_title：Aging clinical and experimental research

authors： Skaar E,Øksnes A,Eide LSP,Norekvål TM,Ranhoff AH,Nordrehaug JE,Forman DE,Schoenenberger AW,Hufthammer KO,Kuiper KK,Bleie Ø,Packer EJS,Langørgen J,Haaverstad R,Schaufel MA

更新日期：2020-03-19 00:00:00

abstract：:The most frequent indication for Calcium Channel Blockers (CCBs) is their use as antihypertensive agents for primary or secondary stroke prevention. Hypertension contributes to virtually all mechanisms of stroke, of atherothrombotic, lacunar, cardioembolic and intraparenchymal hemorrhage types. In comparison with the ...

journal_title：Aging clinical and experimental research

authors： Inzitari D,Poggesi A

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The purpose of this study was to determine the relationship between whole body energy metabolism measured as oxygen consumption (VO2) and local muscle activity measured by positron emission tomography (PET) and [18F]fluorodeoxyglucose (FDG). METHODS:Ten community- dwelling older women (73-83 yrs) h...

journal_title：Aging clinical and experimental research

authors： Shimada H,Sturnieks D,Endo Y,Kimura Y,Suzuki T,Oda K,Ishii K,Ishiwata K

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:The objective of this article is to review the literature regarding the effectiveness and safety of Nordic walking (NW) in therapeutic rehabilitation in patients of an advanced age. METHODS:Randomized studies comparing NW with different patterns of long-lasting physical rehabilitation in older adults (avera...

journal_title：Aging clinical and experimental research

authors： Skórkowska-Telichowska K,Kropielnicka K,Bulińska K,Pilch U,Woźniewski M,Szuba A,Jasiński R

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND AND AIMS:The process applied to identify fall risks in frail elderly persons remains a matter of debate. We intended to develop a fall screening instrument for clinically defined subgroups of long-term care residents, to be administered by nursing staff. METHODS:Fall risk indicators were selected by multipl...

journal_title：Aging clinical and experimental research

authors： Becker C,Loy S,Sander S,Nikolaus T,Rissmann U,Kron M

更新日期：2005-06-01 00:00:00

abstract：:Parkinson's disease (PD) typically occurs in elderly people and some degree of cognitive impairment is usually present. Cognitive reserve (CR) theory was proposed to explain the discrepancy between the degree of brain pathologies and clinical manifestations. We administered a comprehensive neuropsychological battery t...

journal_title：Aging clinical and experimental research

authors： Ciccarelli N,Monaco MRL,Fusco D,Vetrano DL,Zuccalà G,Bernabei R,Brandi V,Pisciotta MS,Silveri MC

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND/AIM:Polypharmacy and inappropriate medication use in older adults is a major public health problem associated with morbidity and mortality. Aging is associated with metabolic changes and decreased drug clearance, increased drug-drug interactions, prescribing cascades, and potentially inappropriate medication...

journal_title：Aging clinical and experimental research

authors： Kucukdagli P,Bahat G,Bay I,Kilic C,Oren MM,Turkmen BO,Karan MA

更新日期：2020-04-01 00:00:00

abstract：:Risk for or established malnutrition is frequent in older adults, accompanied by functional limitations, increased morbidity and mortality. Protein-energy malnutrition is often observed and leads besides other predisposing factors to sarcopenia, the increased loss of muscle mass with aging. Sarcopenia is an integral c...

journal_title：Aging clinical and experimental research

authors： Sieber CC

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Given the progressive demographic ageing of the population and the National Health System reforms affecting care at the bedside, a periodic re-evaluation of in-hospital mortality rates and associated factors is recommended. AIMS:To describe the occurrence of in-hospital mortality among patients admitted to ...

journal_title：Aging clinical and experimental research

authors： Ambrosi E,De Togni S,Guarnier A,Barelli P,Zambiasi P,Allegrini E,Bazoli L,Casson P,Marin M,Padovan M,Picogna M,Taddia P,Salmaso D,Chiari P,Frison T,Marognolli O,Canzan F,Saiani L,Palese A

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Identification of predictive factors on institutionalization provides the basis for the development and application of preadmission assessment. There is a lack of evidence for predictors of institutionalization for older people. AIMS:To examine the effect of predictive factors on institutionalization in hom...

journal_title：Aging clinical and experimental research

authors： Salminen M,Vire J,Viikari L,Vahlberg T,Isoaho H,Lehtonen A,Viitanen M,Arve S,Eloranta S

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Nursing home institutionalization tends to exacerbate loss of functioning. AIMS:Examine the feasibility and the effect of a psychomotor intervention-a multimodal exercise program promoting simultaneous cognitive and motor stimulation-on the executive (planning ability and selective attention) and physical f...

journal_title：Aging clinical and experimental research

authors： Pereira C,Rosado H,Cruz-Ferreira A,Marmeleira J

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Peptydil prolyl cis-trans isomerase (PIN-1), which specifically regulates the conformational changes following phosphorylation of several proteins, targets the inactive hyper-phosphorylated tau on the Thr231-Pro motif and directly restores its biological function. Interestingly, PIN-1 is oxidatively...

journal_title：Aging clinical and experimental research

authors： Arosio B,Segat L,Milanese M,Galimberti L,Calabresi C,Zanetti M,Trabattoni D,Annoni G,Crovella S,Vergani C

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Accumulation of aggregated α-synuclein from the enteric nervous system is believed to be involved in the pathogenesis of Parkinson's disease (PD). The appendix contains abundant α-synuclein and lacks a blood-tissue barrier, suggesting that appendectomy might reduce α-synuclein aggregation, and therefore the ...

journal_title：Aging clinical and experimental research

authors： Lu HT,Shen QY,Xie D,Zhao QZ,Xu YM

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:A lack of understanding of the causes of attrition in longitudinal studies of older adults may lead to higher attrition rates and bias longitudinal study results. In longitudinal epidemiological studies of Alzheimer's disease and related dementias, high rates of attrition may cause a systematic underestimatio...

journal_title：Aging clinical and experimental research

authors： Burke SL,Hu T,Naseh M,Fava NM,O'Driscoll J,Alvarez D,Cottler LB,Duara R

更新日期：2019-09-01 00:00:00

abstract：:MPI_AGE is a European Union co-funded research project aimed to use the Multidimensional Prognostic Index (MPI), a validated Comprehensive Geriatric Assessment (CGA)-based prognostic tool, to develop predictive rules that guide clinical and management decisions in older people in different European countries. A series...

journal_title：Aging clinical and experimental research

authors： Cruz-Jentoft AJ,Daragjati J,Fratiglioni L,Maggi S,Mangoni AA,Mattace-Raso F,Paccalin M,Polidori MC,Topinkova E,Ferrucci L,Pilotto A,MPI_AGE Investigators.

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:The majority of older adults do not reach the physical activity guidelines. One possible explanation for this may be that older adults overestimate their physical activity levels, because they are unable to identify exercise intensity. METHODS:Forty-four older adults were recruited and randomly assigned int...

journal_title：Aging clinical and experimental research

authors： McLellan AG,Slaght J,Craig CM,Mayo A,Sénéchal M,Bouchard DR

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:Using biomarkers to predict mortality in patients with sepsis is important because these patients frequently have high mortality rates and unsatisfactory outcomes. The performance of N-terminal pro-brain natriuretic peptide (NT-pro-BNP) and C-reactive protein (CRP) to predict clinical outcomes in elderly s...

journal_title：Aging clinical and experimental research

authors： Li H,Shan-Shan Z,Jian-Qiang K,Ling Y,Fang L

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Cognitive and physical deficits independently raise the risk for negative events in older adults. Less is known about whether their co-occurrence constitutes a distinct risk profile. This study quantifies the association between cognitive impairment, no dementia (CIND), slow walking speed (WS) and their comb...

journal_title：Aging clinical and experimental research

authors： Grande G,Vetrano DL,Fratiglioni L,Marseglia A,Vanacore N,Laukka EJ,Welmer AK,Rizzuto D

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Diverticular disease of the colon also affects older people. Generally, older patients with diverticulitis may be regarded as too risky to undergo surgery. This retroprospective multicentric observational study aims to assess the safety and benefits of laparoscopic peritoneal lavage (LPL) in elderly patients...

journal_title：Aging clinical and experimental research

authors： Boselli C,Gemini A,Cirocchi R,Grassi V,Avenia S,Polistena A,Sanguinetti A,Pironi D,Santoro A,Tabola R,Burattini MF,Avenia N

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Sagittal spinal alignment is an important determinant for proper spinal function. Alterations in spinal alignment may serve as leading factor for diminished body biomechanics. Although increased age is suggested to be associated with changes in lumbosacral alignment, in turn body posture, this is still a cur...

journal_title：Aging clinical and experimental research

authors： Coskun Benlidayi I,Basaran S

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:For people with dementia, moving into a nursing home is usually considered at some point in time. Currently available information on predictors of institutionalization is often based on small sample sizes, not taking competing risks into account, and with inconclusive results for sex. AIMS:We aimed to carry...

journal_title：Aging clinical and experimental research

authors： Runte R

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Poor adherence to medications is a major health concern especially among older subjects. To plan future studies to improve adherence, an epidemiological study, called "Fiesole Misurata", was conducted. The aim of the present paper was to verify the representativeness of the database in evaluating th...

journal_title：Aging clinical and experimental research

authors： Lapi F,Lucenteforte E,Moschini M,Bonaiuti R,Di Pirro M,Barchielli A,Benemei S,Belladonna M,Nesti N,Coppini R,Taras M,Vannacci A,Ungar A,Mugelli A

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Gender and age effect on brain morphology have been extensively investigated. However, the great variety in methods applied to morphology partly explain the conflicting results of linear patterns of tissue changes and lateral asymmetry in men and women. The aim of the present study was to assess the...

journal_title：Aging clinical and experimental research

authors： Riello R,Sabattoli F,Beltramello A,Bonetti M,Bono G,Falini A,Magnani G,Minonzio G,Piovan E,Alaimo G,Ettori M,Galluzzi S,Locatelli E,Noiszewska M,Testa C,Frisoni GB

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The number of older persons admitted to the Emergency Department (ED) is dramatically increasing due to their complex medical and social problems, which in turn lead to longer clinical evaluation times and increased use of resources compared to younger adults. However, scant data are available for I...

journal_title：Aging clinical and experimental research

authors： Salvi F,Mattioli A,Giannini E,Vita D,Morichi V,Fallani M,Dessì-Fulgheri P,Cherubini A

更新日期：2013-10-01 00:00:00