Abstract:
BACKGROUND:Despite the increase in research on delirium, it remains underdiagnosed and difficult to manage, and the outcome is poor especially in older people. AIMS:To identify the clinically diagnosed rates of delirium, the possible aetiologies, to describe treatment, number and type of psychotropic medication used and to investigate the reasons for referral to a liaison psychiatric team. METHODS:Retrospective study of medical records of inpatients admitted to Sligo Regional Hospital during an 18-month period. RESULTS:One hundred and fifty-six files had a documentation of delirium (time prevalence 2%). Mean age of the sample was 82 years (SD = 7.2), 66 (42%) were male. Sixty-nine (44.2%) of the total sample had a previous history of dementia, and 57 (36.5%) had a previous history of delirium. In 67 (43.2%) samples, the cause was infection, while in 4, no specific cause was identified. Ninety (58%) were referred to the liaison service, but only in 26 (28.9 %), the reason for referral was "acute confusion" or "delirium". In a majority of referrals, the reason was an affective disorder more often depression. There were no significant differences between delirium subtypes and referrals (χ(2) = 3.868, df 3, p = 0.28). Examination of the amount of antipsychotics prescribed before, during and after delirium shows that there was a significant increase in use during the delirium (χ(2) = 17.512, df 8, p = 0.025) and decrease in z-hypnotics medication (zopiclone/zolpidem), (χ(2) = 20.114, df 4, p < 0.001), while benzodiazepines and antidepressants remained the same. CONCLUSIONS:Delirium is often misdiagnosed and unrecognized in hospital settings; however, when identified the pharmacological management is appropriate.
journal_name
Aging Clin Exp Resjournal_title
Aging clinical and experimental researchauthors
Rooney S,Qadir M,Adamis D,McCarthy Gdoi
10.1007/s40520-014-0227-xsubject
Has Abstractpub_date
2014-12-01 00:00:00pages
625-33issue
6eissn
1594-0667issn
1720-8319journal_volume
26pub_type
杂志文章abstract:BACKGROUND AND AIMS:Although the role of afferent input from cervical muscles on the control of posture and locomotion is recognised, it is surprising that there is an absence of data reporting whether joint position sense at the cervical level is impaired in older healthy adults. The present experiment was designed to...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324868
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND AND AIMS:An accurate diagnosis of sarcopenia is required. The aim of this study is to correlate the results of two methods to define sarcopenia using cross sectional body composition data, with actual loss of fat free mass. METHODS:Healthy older subjects (926 females and 381 males aged 70 years or more) and...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324705
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND AND AIMS:Nitric oxide (NO) may play a critical role in facilitating the delivery of blood to active skeletal muscle, ultimately impacting functional health in older adults. Plasma nitrite is a useful marker of vascular NO bioavailability. The aim of the current investigation was to examine the effect of a wi...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.3275/6734
更新日期:2010-10-01 00:00:00
abstract::Osseointegration is a term that refers to the formation of a direct interface between an implant and bone without intervening soft tissue. Cementless femoral fixation in total hip arthroplasty is dependent on mechanical and biological factors that affect implant stability and long-term outcome. Osteoporosis leads to m...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-013-0103-0
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND AND AIMS:Lumbar spinal stenosis (LSS), osteoarthritis (OA) of the knee, and osteoporosis are major locomotive diseases in the elderly population. The aim of this study was to examine the effectiveness of exercise in these three diseases. METHODS:We reviewed the relevant literature, i.e., systematic reviews ...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,评审
doi:10.1007/BF03324783
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Muscle weakness and 25-hydroxyvitamin D (25(OH)D) deficiency have been associated with adverse outcomes among older adults. However, little is known about the relationship between clinically relevant muscle weakness and 25(OH)D levels in Ecuador. AIMS:To examine the prevalence of muscle weakness and its ass...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-016-0678-3
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND AND AIMS:Poor adherence to medications is a major health concern especially among older subjects. To plan future studies to improve adherence, an epidemiological study, called "Fiesole Misurata", was conducted. The aim of the present paper was to verify the representativeness of the database in evaluating th...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-013-0060-7
更新日期:2013-08-01 00:00:00
abstract::The increase in the aged population led to a global rise in the demand for elderly healthcare services, such as long-term care facilities (LTCFs), nursing homes, residential homes. Unfortunately, the spread of multidrug-resistant organisms (MDROs) in these structures represent an urgent public health threat requiring ...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-020-01746-2
更新日期:2021-01-11 00:00:00
abstract:BACKGROUND:Inappropriate prescribing in elderly patients is a widespread health problem. It is associated with increased drug-related problems and health expenditure. AIMS:To determine the prevalence and types of potentially inappropriate medications (PIM) prescribed to elderly patients with polypharmacy and the facto...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-017-0742-7
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Gender and age effect on brain morphology have been extensively investigated. However, the great variety in methods applied to morphology partly explain the conflicting results of linear patterns of tissue changes and lateral asymmetry in men and women. The aim of the present study was to assess the...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324618
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND:Elderly people experience a gradual loss of muscle strength and a reduction of serum levels of vitamin D and of vitamin D receptor expression in skeletal muscle cells. AIMS:The aim of our study was to evaluate the association among serum levels of 25-hydroxy-vitamin D [25(OH)D3], muscle strength, and physic...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-015-0405-5
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND AND AIMS:Glycemic control in geriatric patients with type 2 diabetes (T2DM) remains clinically challenging. The objective of this study was to compare the safety and efficacy of insulin lispro in patients C65 years (geriatric) to those\65 years (non-geriatric), using a metaanalysis of randomized controlled c...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,meta分析
doi:10.1007/s40520-013-0125-7
更新日期:2014-02-01 00:00:00
abstract:INTRODUCTION:Despite the use of the new generation P2Y12 inhibitors (Ticagrelor and Prasugrel) with aspirin is the recommended therapy in acute NSTE-ACS patients, their current use in clinical practice remains quite low and might be related, among several variables, with increased comorbidity burden. We aimed to assess...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,多中心研究
doi:10.1007/s40520-019-01348-7
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Asymmetric vestibular function, decreased plantar sensation, postural control and functional ability have been associated with fall-related wrist fractures. OBJECTIVE:To investigate whether multi-sensory training (MST) improves postural control, vestibular function, foot sensation and functional ability amo...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s40520-019-01143-4
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Dehydration is the most common fluid or electrolyte disorder among older persons. This study was designed to examine the hydration status of community-dwelling seniors. METHODS:Blood and urine samples were collected from 67 independently living volunteers (65-93 yrs) who had functional limitations ...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,多中心研究
doi:10.1007/BF03324513
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVE:Attitude of healthcare providers toward older people is very important in the aging world. Neurologists contact older adults very frequently. We aimed to investigate the attitudes of neurologists toward older adults. MEASUREMENTS:We recorded participants age; sex; duration of clinical practice in neurology; ...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-016-0606-6
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:A lack of understanding of the causes of attrition in longitudinal studies of older adults may lead to higher attrition rates and bias longitudinal study results. In longitudinal epidemiological studies of Alzheimer's disease and related dementias, high rates of attrition may cause a systematic underestimatio...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-018-1087-6
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND AND AIMS:With an increasing population aged 85 years and over, the aim of this study was to describe health status and living conditions in the oldest old and to estimate age and sex differences in a Northern European population. METHODS:A population-based cross-sectional study, The Umeå 85+ Study, was carr...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03327426
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:Oxidative stress is strongly associated with aging and age-related diseases and plays a crucial role in endothelial dysfunction development. AIM:To better understand the molecular mechanisms of aging and stress response in humans, we examined changes to young and older human endothelial cells over time (72,...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-015-0357-9
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:The majority of older adults do not reach the physical activity guidelines. One possible explanation for this may be that older adults overestimate their physical activity levels, because they are unable to identify exercise intensity. METHODS:Forty-four older adults were recruited and randomly assigned int...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-017-0746-3
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Resistance training holds promise for nursing home residents to prevent further disabilities, falls, and fractures. Free weight as well as machine training may offer an efficient option to improve physical performance, but the feasibility of these training regimes among elderly who require continuous institu...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s40520-017-0830-8
更新日期:2018-07-01 00:00:00
abstract:AIM:We report 3 cases of spontaneous insufficiency fracture of long bones, to promote awareness of this phenomenon to medical personnel dealing with long-term bedridden patients. METHODS:Cases were analyzed in the light of a literature review. RESULTS:Our patients were all women, who were severely debilitated and had...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324821
更新日期:2010-02-01 00:00:00
abstract::The occurrence of a given disease in a population is measured by prevalence and incidence. Prevalence reflects the burden of a given disease in a specific population and is calculated as point prevalence or period prevalence. Incidence denotes the number of new cases of a given disease which occur in a cohort of indiv...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,评审
doi:10.1007/BF03325157
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND AND AIMS:Whether or not there has been a "compression of morbidity" in older ages has been vividly debated during the last decades. Previous studies have found indications of both improved and deteriorated health among elderly persons. Few studies have analyzed how changes in health indicators are influenced...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324463
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:Hip fractures (HF) are a major issue worldwide. We aimed at evaluating the practices in delivering care to patients with HF among several Italian Orthogeriatric centers. METHODS:The study took place from February 2016 to July 2018. Seven performance indicators (pre-surgical cognitive assessment, surgery per...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-020-01488-1
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND AND AIMS:The relative weight of various etiologies of dementia and mild cognitive impairment (MCI) as predictors of intra-hospital, short- and long-term mortality in very old acutely ill patients suffering from multiple comorbid conditions remains unclear. We investigated intra-hospital, 1- and 5-year mortal...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324953
更新日期:2011-02-01 00:00:00
abstract:AIM:Falls are a significant problem for older people, but are few studies of the risk of falling in residents of nursing homes in Japan. We aimed to investigate the risk factors for falls and the association of medication use and falls in nursing home residents in Japan. METHODS:This case-control study reviewed the re...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-019-01265-9
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND AND AIMS:Diagnosis of dementia is often difficult in subjects with low educational level. Our aim was to evaluate the role of functional performance and the possibility of preferring scores of activities of daily living (ADL) and instrumental activities of daily living (IADL) in screening elderly people for ...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324675
更新日期:2007-04-01 00:00:00
abstract::Celiac disease is a genetic disorder, presenting with malabsorption-related problems because of mucosal damage after ingestion of gluten. The only known effective treatment is a gluten-free diet. Early diagnosis and treatment are essential in preventing complications due to malabsorption. Here we report the case of an...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324644
更新日期:2006-02-01 00:00:00
abstract::Risk for or established malnutrition is frequent in older adults, accompanied by functional limitations, increased morbidity and mortality. Protein-energy malnutrition is often observed and leads besides other predisposing factors to sarcopenia, the increased loss of muscle mass with aging. Sarcopenia is an integral c...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,评审
doi:10.1007/s40520-019-01170-1
更新日期:2019-06-01 00:00:00