当前位置： SCI文献检索 > AGING CLINICAL AND EXPERIMENTAL RESEARCH期刊下所有文献 > Drugs and falls in older people in geriatric care settings.

Drugs and falls in older people in geriatric care settings.

Abstract：

BACKGROUND AND AIMS:Falls and their consequences constitute serious health problems in the older population. The aim was to study predisposing factors for falls among older people in geriatric care settings, focusing on drugs. METHODS:This population-based study, with a cross-sectional design, analysed all geriatric care settings, comprising 68 residential care facilities, 31 nursing homes, 66 group dwellings for people with dementia, seven rehabilitation/short-stay units, two somatic geriatric and two psychogeriatric clinics, in the county of Västerbotten; 3604 residents with a mean age of 83.3+/-7.0 (65-103) years (68% women) were included. The residents were assessed by means of the Multi-Dimensional Dementia Assessment Scale (MDDAS) that measures, for example, mobility, paresis, vision, hearing, functions of activities of daily living (ADL), and behavioural and psychiatric symptoms. Drug consumption and falls during the previous week were recorded. RESULTS:Three hundred and one residents (8.4%) had sustained a fall at least once during the preceding week. Multivariate analyses showed that a history of falls, the ability to get up from a chair, the need for a helper when walking, pain, cognitive impairment, and use of neuroleptics or antidepressants were all associated with being a faller. Among the antidepressants, selective serotonin reuptake inhibitors (SSRIs) but not serotonin and noradrenalin reuptake inhibitors (SNRIs) were associated with falls. Cholinesterase inhibitors were not associated with falls. CONCLUSIONS:Like functional and cognitive impairment, treatments with antidepressants and neuroleptics are predisposing factors for falls in older people in residential care. However, there seem to be differences between subgroups among these drugs and, from the perspective of fall prevention, SNRIs rather than SSRIs should perhaps be preferred in the treatment of depression in older people.

journal_name

Aging Clin Exp Res

journal_title

Aging clinical and experimental research

authors

Kallin K,Gustafson Y,Sandman PO,Karlsson S

doi

10.1007/BF03324551

subject

Has Abstract

pub_date

2004-08-01 00:00:00

pages

270-6

issue

4

eissn

1594-0667

issn

1720-8319

journal_volume

16

pub_type

杂志文章

相关文献

AGING CLINICAL AND EXPERIMENTAL RESEARCH文献大全
  • Evaluation of renal function in the elderly, not as easy as it seems: a review.

    abstract：:In the elderly assessment of renal function by glomerular filtration rate estimation is crucial for diagnostic, therapeutic and prognostic purposes. Our aim is to illustrate the different formulas available and their respective advantages and disadvantages. ...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章,评审

    doi：10.1007/s40520-014-0311-2

    authors： Ungar A,Iacomelli I,Giordano A,Roberts AT,Rafanelli M,Marchionni N

    更新日期：2015-08-01 00:00:00

  • Coordination of trunk and foot acceleration during gait is affected by walking velocity and fall history in elderly adults.

    abstract：BACKGROUND:Falling is a significant concern for many elderly adults but identifying individuals at risk of falling is difficult, and it is not clear how elderly adults adapt to challenging walking. AIMS:The aim of the current study was to determine the effects of walking at non-preferred speeds on the coordination bet...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/s40520-018-1036-4

    authors： Craig JJ,Bruetsch AP,Huisinga JM

    更新日期：2019-07-01 00:00:00

  • Diagnosis of Anderson-Fabry's disease in over seventy-year-old women: description of two cases.

    abstract：:Anderson-Fabry's disease (AFD) is a rare inborn X-linked sphingolipid storage disorder. Deficient activity of the lysosomal enzyme alpha-galactosidase A (alpha-GAL-A) leads to progressive accumulation of glycosphingolipids within most visceral tissues and body fluids of affected patients, provoking a clinical syndrome...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/BF03324669

    authors： Buechner S,Luzzi C,Mannucci M,Massi D,Borsini W

    更新日期：2006-08-01 00:00:00

  • Clinically silent idiopathic Parkinson's disease unmasked by valproate use: a brief report.

    abstract：:Valproate is an important but uncommon cause of drug induced parkinsonism in the elderly. The development of symptoms after valproate onset is unpredictable, and severity of symptoms is unrelated to plasma levels. However, though the majority of cases improve after drug cessation, parkinsonian symptoms can persist and...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/s40520-014-0278-z

    authors： Athauda D,Batley R,Ellis C

    更新日期：2015-06-01 00:00:00

  • Health status in the oldest old. Age and sex differences in the Umeå 85+ Study.

    abstract：BACKGROUND AND AIMS:With an increasing population aged 85 years and over, the aim of this study was to describe health status and living conditions in the oldest old and to estimate age and sex differences in a Northern European population. METHODS:A population-based cross-sectional study, The Umeå 85+ Study, was carr...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/BF03327426

    authors： von Heideken Wågert P,Gustavsson JM,Lundin-Olsson L,Kallin K,Nygren B,Lundman B,Norberg A,Gustafson Y

    更新日期：2006-04-01 00:00:00

  • The occurrence of acute myocardial infarction in Italy: a five-year analysis of hospital discharge records.

    abstract：BACKGROUND:The incidence and costs of acute myocardial infarction (AMI) in Europe represent a substantial problem due to population aging. METHODS:Between 2001 and 2005, Italian hospitalization records were examined to evaluate hospital admissions and costs of AMI in adults aged ≥ 45 and in elderly people ≥ 65 or ≥ 75...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/BF03337744

    authors： Piscitelli P,Iolascon G,Greco M,Marinelli A,Gimigliano F,Gimigliano R,Gisonni P,Giordano A,Migliore A,Granata M,Tarantino U,Brandi ML,Baggiani A,Distante A

    更新日期：2011-02-01 00:00:00

  • Diagnostic and treatment practices of delirium in a general hospital.

    abstract：BACKGROUND:Despite the increase in research on delirium, it remains underdiagnosed and difficult to manage, and the outcome is poor especially in older people. AIMS:To identify the clinically diagnosed rates of delirium, the possible aetiologies, to describe treatment, number and type of psychotropic medication used a...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/s40520-014-0227-x

    authors： Rooney S,Qadir M,Adamis D,McCarthy G

    更新日期：2014-12-01 00:00:00

  • Nutritional status, physical performance and disability in the elderly of the Peruvian Andes.

    abstract：BACKGROUND:Although nutritional status plays an important part in the physical performance and disability of older people, this relationship has been little studied in developing countries. AIMS:A study on the effects of nutritional status on the physical performance and functional status of elderly people living in r...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/s40520-016-0591-9

    authors： Tramontano A,Veronese N,Giantin V,Manzato E,Rodriguez-Hurtado D,Trevisan C,De Zaiacomo F,Sergi G

    更新日期：2016-12-01 00:00:00

  • Baseline frailty status and outcomes important for shared decision-making in older adults receiving transcatheter aortic valve implantation, a prospective observational study.

    abstract：AIMS:The objective of this study was to examine baseline frailty status (including cognitive deficits) and important clinical outcomes, to inform shared decision-making in older adults receiving transcatheter aortic valve implantation (TAVI). METHODS AND RESULTS:We conducted a prospective, observational study of 82 TA...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/s40520-020-01525-z

    authors： Skaar E,Øksnes A,Eide LSP,Norekvål TM,Ranhoff AH,Nordrehaug JE,Forman DE,Schoenenberger AW,Hufthammer KO,Kuiper KK,Bleie Ø,Packer EJS,Langørgen J,Haaverstad R,Schaufel MA

    更新日期：2020-03-19 00:00:00

  • Cardiovascular mortality and C-reactive protein in elderly patients beginning dialysis: reverse epidemiology?

    abstract：BACKGROUND AND AIMS:Cardiovascular disease is a major cause of mortality in end-stage renal disease patients (ESRD). The rate of elderly and polypathologic patients in ESRD is increasing. Elevated levels of C-reactive protein (CRP) have been shown to be associated with increased mortality in ESRD patients. The aim of t...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/BF03325234

    authors： Millet C,Bosson JL,Pernod G,Wauters JP,Couturier P,Quesada JL,Zaoui P

    更新日期：2011-10-01 00:00:00

  • The effect of aging on gait parameters in able-bodied older subjects: a literature review.

    abstract：BACKGROUND:Gait disorders are common in the elderly populations, and their prevalence increases with age. Abnormal gait has been associated with greater risk for adverse outcomes in older adults, such as immobility and falls, which in turn lead to loss of functional independence and death. AIM:The purpose of this revi...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章,评审

    doi：10.1007/s40520-015-0420-6

    authors： Aboutorabi A,Arazpour M,Bahramizadeh M,Hutchins SW,Fadayevatan R

    更新日期：2016-06-01 00:00:00

  • Monochromatic phototherapy: effective treatment for grade II chronic pressure ulcers in elderly patients.

    abstract：BACKGROUND AND AIMS:Monochromatic pulsating light may have effects on wound healing. In an earlier study of grade II ulcers, there was a tendency toward better healing in the phototherapy group (p=0.06). The present study on patients with grade II ulcers was performed to verify these findings. Data from this study were...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/BF03324734

    authors： Dehlin O,Elmståhl S,Gottrup F

    更新日期：2007-12-01 00:00:00

  • Lokomat training in vascular dementia: motor improvement and beyond!

    abstract：:Vascular dementia (VaD) is a general term describing problems with reasoning, planning, judgment, memory, and other thought processes caused by brain damage from impaired blood flow to the brain. Cognitive rehabilitation and physical therapy are the mainstays of dementia treatment, although often ineffective because o...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/s40520-015-0343-2

    authors： Calabrò RS,De Luca R,Leo A,Balletta T,Marra A,Bramanti P

    更新日期：2015-12-01 00:00:00

  • Evaluation of an osteoporosis and fall risk intervention program for community-dwelling elderly. A quasi-experimental study of behavioral modifications.

    abstract：BACKGROUND AND AIMS:Osteoporosis and fall fractures are increasing problems amongst the elderly. The aim of this study was to explore whether combined population-based and individual interventions directed at risk factors for osteoporosis and falls result in behavioral changes in an elderly population. METHODS:A quasi...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/BF03324654

    authors： Grahn Kronhed AC,Blomberg C,Löfman O,Timpka T,Möller M

    更新日期：2006-06-01 00:00:00

  • Production of nitric oxide, lipid peroxidation and oxidase activity of ceruloplasmin in blood of elderly patients with primary hypertension. Effects of perindopril treatment.

    abstract：BACKGROUND AND AIMS:One of the factors playing a role in both the aging process and the etiopathogenesis of primary hypertension is oxidative stress. The purpose of this work was to estimate the production of nitric oxide (NO), oxidase activity of ceruloplasmin (Cp) and level of malondialdehyde (MDA), the end-product o...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/BF03324634

    authors： Kedziora-Kornatowska K,Kornatowski T,Bartosz G,Pawluk H,Czuczejko J,Kedziora J,Szadujkis-Szadurski L

    更新日期：2006-02-01 00:00:00

  • Predictive value of C-reactive protein and NT-pro-BNP levels in sepsis patients older than 75 years: a prospective, observational study.

    abstract：INTRODUCTION:Using biomarkers to predict mortality in patients with sepsis is important because these patients frequently have high mortality rates and unsatisfactory outcomes. The performance of N-terminal pro-brain natriuretic peptide (NT-pro-BNP) and C-reactive protein (CRP) to predict clinical outcomes in elderly s...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/s40520-019-01244-0

    authors： Li H,Shan-Shan Z,Jian-Qiang K,Ling Y,Fang L

    更新日期：2020-03-01 00:00:00

  • Voluntary exercise and mild food restriction effectively retard the collagen biomarker of aging.

    abstract：BACKGROUND AND AIMS:Obesity and lack of physical exercise characterize increasing numbers of people in Western societies, resulting in increasing morbidity and mortality. Regular physical exercise, on the other hand, has been shown to be beneficial. Beneficial effects have also been shown in laboratory rodent studies--...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/BF03327370

    authors： Viidik A,Skalicky M

    更新日期：2003-12-01 00:00:00

  • Measuring physical performance in highly active older adults: associations with age and gender?

    abstract：BACKGROUND:Higher age is associated with reduced physical capability in the general population. The role of age and gender for physical performance in older adults who exercises regularly is, however, not clear, and there is also a lack of recommendations for outcomes to address physical performance for this population...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/s40520-019-01190-x

    authors： Tangen GG,Robinson HS

    更新日期：2020-02-01 00:00:00

  • Acute lymphocytic leukemia with eosinophilia: a case report and review of the literature.

    abstract：:We present a 61-year-old man with marked peripheral blood eosinophilia, feature of hypereosinophilic syndrome, that later evolved into acute lymphocytic leukemia (ALL-L2). Initially the patient suffered from significant complications related to eosinophilic toxicity, including large urticarial hyperpigmented plaques, ...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章,评审

    doi：10.3275/8337

    authors： Song G,Liu H,Sun F,Gu L,Wang S

    更新日期：2012-10-01 00:00:00

  • Serum superoxide dismutase and malondialdehyde levels in a group of Chinese patients with age-related macular degeneration.

    abstract：BACKGROUND AND AIMS:The aim of this study was to investigate superoxide dismutase (SOD) activity together with malondialdehyde (MDA) levels in a group of Chinese patients with age-related macular degeneration (AMD). METHODS:Serum SOD activity and MDA levels were analysed in 56 AMD patients with subtypes (early dry, ge...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/BF03324965

    authors： Jia L,Dong Y,Yang H,Pan X,Fan R,Zhai L

    更新日期：2011-08-01 00:00:00

  • Educational vaccine tools: the French initiative.

    abstract：:Prevention is an important but neglected issue in geriatric medicine. Vaccination plays a major role in prevention of infectious diseases, but its implementation in clinical practice is far from perfect. To improve practice, a group of French experts composed of geriatricians and infectious disease specialists prepare...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/BF03324906

    authors： Belmin J,Bourée P,Camus D,Guiso N,Jeandel C,Trivalle C,Veyssier P

    更新日期：2009-06-01 00:00:00

  • Stepping down backwards as a means of detecting biomechanical differences between healthy older and younger adults.

    abstract：BACKGROUND AND AIMS:Changes in sensory- motor systems that occur with age result in a decrease in postural equilibrium, which has been linked with an increased risk of falling in the elderly. Stepping down backwards from a step perturbs dynamic postural equilibrium, thus offering an opportunity to analyze the biomechan...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/BF03324776

    authors： Michel-Pellegrino V,Hewson D,Hogrel JY,Duchêne J

    更新日期：2008-06-01 00:00:00

  • The incidence of fragility fractures in Italy.

    abstract：:Osteoporosis can significantly impact on the risk of developing a fracture. Thus, fragility fractures represent a challenge for health professionals and decision makers of the twenty-first century. The aim of this work is to review the literature concerning osteoporotic fractures in Italy in terms of incidence, rate o...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章,评审

    doi：10.1007/s40520-013-0071-4

    authors： Ratti C,Vulcano E,La Barbera G,Canton G,Murena L,Cherubino P

    更新日期：2013-10-01 00:00:00

  • Effects of denosumab on cortical and trabecular microarchitecture: evidences from clinical studies.

    abstract：:Excess of bone remodeling is still the major pathogenic factor in involutional osteoporosis. This phenomenon is linked to an imbalance between neoformation (by osteoblasts) and resorption (by osteoclasts). Recently, research in drug development is focused on new and more "physiological" approach to balance bone remode...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章,评审

    doi：10.1007/s40520-013-0086-x

    authors： Iolascon G,Resmini G,Tarantino U

    更新日期：2013-10-01 00:00:00

  • Concordance between clinical and radiographic evaluations of knee osteoarthritis.

    abstract：BACKGROUND:Significant correlation has been previously demonstrated between radiographic and clinical diagnoses of knee osteoarthritis (OA); however, the specific findings on clinical examination that relate best to a radiographic diagnosis have not been fully elicited. AIMS:We aimed to explore the relationship betwee...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/s40520-017-0847-z

    authors： Parsons C,Fuggle NR,Edwards MH,Goulston L,Litwic AE,Jagannath D,van der Pas S,Cooper C,Dennison EM,EPOSA Research Group.

    更新日期：2018-01-01 00:00:00

  • Reliability and validity of the Turkish version of the Nottingham Extended Activities of Daily Living Scale.

    abstract：BACKGROUND AND AIMS:The aim of this study was to develop a Turkish version of the Nottingham Extended Activities of Daily Living Scale (NEADLS) and to assess its reliability and validity. METHODS:Sixty healthy volunteers over 67 years old were included in the study. After translation, the Turkish version of the scale ...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/BF03325144

    authors： Sahin F,Yilmaz F,Ozmaden A,Kotevoglu N,Sahin T,Kuran B

    更新日期：2008-10-01 00:00:00

  • Feasibility of a machine vs free weight strength training program and its effects on physical performance in nursing home residents: a pilot study.

    abstract：BACKGROUND:Resistance training holds promise for nursing home residents to prevent further disabilities, falls, and fractures. Free weight as well as machine training may offer an efficient option to improve physical performance, but the feasibility of these training regimes among elderly who require continuous institu...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s40520-017-0830-8

    authors： Johnen B,Schott N

    更新日期：2018-07-01 00:00:00

  • Initiation of antipsychotics after moving to residential aged care facilities and mortality: a national cohort study.

    abstract：BACKGROUND:There is a high burden of antipsychotic use in residential aged care facilities (RACFs) and there is concern regarding potential inappropriate prescribing of antipsychotics in response to mild behavioural symptoms. Antipsychotic use has been associated with a higher risk of mortality in community-dwelling ol...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/s40520-020-01518-y

    authors： Harrison SL,Sluggett JK,Lang C,Whitehead C,Crotty M,Corlis M,Wesselingh S,Inacio MC

    更新日期：2020-03-11 00:00:00

  • Lack of association between appendectomy and Parkinson's disease: a systematic review and meta-analysis.

    abstract：BACKGROUND:Accumulation of aggregated α-synuclein from the enteric nervous system is believed to be involved in the pathogenesis of Parkinson's disease (PD). The appendix contains abundant α-synuclein and lacks a blood-tissue barrier, suggesting that appendectomy might reduce α-synuclein aggregation, and therefore the ...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章,meta分析,评审

    doi：10.1007/s40520-019-01354-9

    authors： Lu HT,Shen QY,Xie D,Zhao QZ,Xu YM

    更新日期：2020-11-01 00:00:00

  • Functional status and satisfaction with community participation in persons with stroke following medical rehabilitation.

    abstract：BACKGROUND AND AIMS:Researchers and policy-makers have recognized that quality of life assessments are essential to better understand the benefits of rehabilitation intervention. The purpose of the study was to examine associations between functional status and satisfaction with community participation for persons with...

    journal_title：Aging clinical and experimental research

    pub_type： 杂志文章

    doi：10.1007/BF03337718

    authors： Ostir GV,Smith PM,Smith D,Ottenbacher KJ

    更新日期：2005-02-01 00:00:00