Cellular and molecular mechanisms of new onset seizure generation.

abstract：BACKGROUND AND AIMS:Poor adherence to medications is a major health concern especially among older subjects. To plan future studies to improve adherence, an epidemiological study, called "Fiesole Misurata", was conducted. The aim of the present paper was to verify the representativeness of the database in evaluating th...

journal_title：Aging clinical and experimental research

authors： Lapi F,Lucenteforte E,Moschini M,Bonaiuti R,Di Pirro M,Barchielli A,Benemei S,Belladonna M,Nesti N,Coppini R,Taras M,Vannacci A,Ungar A,Mugelli A

更新日期：2013-08-01 00:00:00

abstract：:The purpose of this study was to evaluate the relationship between 3 eNOS gene polymorphisms and training status (TS) in affecting plasma nitrite concentration (NO2) in normotensive adults over 50 years old. Resting blood pressure (BP) was measured in all participants (n = 101). Plasma was taken to analyze: lipid prof...

journal_title：Aging clinical and experimental research

authors： da Silva RF,Sertório JT,Lacchini R,Trapé AA,Tanus-Santos JE,Rush JW,Amaral SL,Zago AS

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Life-space assessment incorporates all movements in terms of the distance from home, the frequency of movement and the need of assistance for movement. Executive function (EF) is an important higher order cognitive ability that controls and guides people's goal-directed actions. We examined the cross-section...

journal_title：Aging clinical and experimental research

authors： Poranen-Clark T,von Bonsdorff MB,Rantakokko M,Portegijs E,Eronen J,Kauppinen M,Eriksson JG,Rantanen T,Viljanen A

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Osteoporosis is a common disease in elderly, characterized by poor bone quality as a result of alterations affecting trabecular bone. However, recent studies have described also an important role of alterations of cortical bone in the physiopathology of osteoporosis. Although dual-energy X-ray absorptiometry...

journal_title：Aging clinical and experimental research

authors： Feola M,Rao C,Tempesta V,Gasbarra E,Tarantino U

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVES:The circadian rhythm of serum thyroid stimulating hormone (TSH) levels in patients with Alzheimer's disease was measured by means of a case-control study. METHODS:Serum samples from cases and controls were collected continuously for 2 days, and then once every 2 h (even number time-point during the first da...

journal_title：Aging clinical and experimental research

authors： Chen JM,Huang CQ,Ai M,Kuang L

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND AND AIMS:The MDS inter- RAI Acute Care is a comprehensive geriatric assessment tool for hospitalized older persons. The aim was to examine its validity based on test content by use in daily clinical practice. METHODS:Clinical staff of multiple disciplines assessed 256 older persons (83.2±5.2 years; 60% fema...

journal_title：Aging clinical and experimental research

authors： Wellens NI,Deschodt M,Boonen S,Flamaing J,Gray L,Moons P,Milisen K

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Resistance training holds promise for nursing home residents to prevent further disabilities, falls, and fractures. Free weight as well as machine training may offer an efficient option to improve physical performance, but the feasibility of these training regimes among elderly who require continuous institu...

journal_title：Aging clinical and experimental research

authors： Johnen B,Schott N

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Quality monitoring has great relevance in stroke care. The Project "How to guarantee adherence to effective interventions in stroke care" aimed to estimate adherence to acute-phase guidelines in stroke care in Italy. METHODS:A prospective observational study was performed in 27 hospitals of 13 Ital...

journal_title：Aging clinical and experimental research

authors： Di Carlo A,Accetta G,Bellan M,Terni G,Lamassa M,Facchini R,Biggeri A,Inzitari D,Ferro S,National Stroke Care Group.

更新日期：2014-06-01 00:00:00

abstract：:Osteoarthritis (OA) is the most common joint condition and, with a burgeoning ageing population, is due to increase in prevalence. Beyond conventional medical and surgical interventions, there are an increasing number of 'alternative' therapies. These alternative therapies may have a limited evidence base and, for thi...

journal_title：Aging clinical and experimental research

authors： Fuggle NR,Cooper C,Oreffo ROC,Price AJ,Kaux JF,Maheu E,Cutolo M,Honvo G,Conaghan PG,Berenbaum F,Branco J,Brandi ML,Cortet B,Veronese N,Kurth AA,Matijevic R,Roth R,Pelletier JP,Martel-Pelletier J,Vlaskovska M,Thoma

更新日期：2020-04-01 00:00:00

abstract：AIM:The main purpose of the present study was to verify the feasibility of wearable inertial sensors (IMUs) in a clinical setting to screen gait and functional mobility in Italian older persons. In particular, we intended to verify the capability of IMUs to discriminate individuals with and without cognitive impairment...

journal_title：Aging clinical and experimental research

authors： Mulas I,Putzu V,Asoni G,Viale D,Mameli I,Pau M

更新日期：2020-09-25 00:00:00

abstract：BACKGROUND AND AIMS:Fast- and usual-paced 400-m walking tests are often used to assess physical fitness or function, respectively, though it is not known how performance converges on these tests. This study aims to determine whether performance on the fast- and usual-paced 400-m walks varies based upon age and physical...

journal_title：Aging clinical and experimental research

authors： Lange-Maia BS,Newman AB,Strotmeyer ES,Harris TB,Caserotti P,Glynn NW

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Obesity and lack of physical exercise characterize increasing numbers of people in Western societies, resulting in increasing morbidity and mortality. Regular physical exercise, on the other hand, has been shown to be beneficial. Beneficial effects have also been shown in laboratory rodent studies--...

journal_title：Aging clinical and experimental research

authors： Viidik A,Skalicky M

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND AND AIMS:To evaluate the effect of interdisciplinary outpatient geriatrics on the use, cost, and quality of health services in a fee-for-service (FFS) environment of two networks of primary care clinics operated by a not-for-profit provider organization in Dallas County, Texas. METHODS:The Senior Health Net...

journal_title：Aging clinical and experimental research

authors： Famadas JC,Frick KD,Haydar ZR,Nicewander D,Ballard D,Boult C

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Slow walking speed as one indicator of physical frailty has been found to be associated with deterioration of the health status. Although many reports have shown that exercise training improves motor function, it is unclear whether a group-based and short-term health promotion intervention will improve motor...

journal_title：Aging clinical and experimental research

authors： Kutsuna T,Hiyama Y,Kusaka S,Kusumoto Y,Tsuchiya J,Umeda M,Takahashi T

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Most elderly persons live in developing countries where current geriatric epidemiological data are scarce. We aimed to study major comorbidities, polypharmacy, functional and nutritional status in a Turkish community-dwelling female elderly clinic population. METHODS:Female geriatrics outpatient cl...

journal_title：Aging clinical and experimental research

authors： Bahat G,Tufan F,Bahat Z,Tufan A,Aydin Y,Akpinar TS,Nadir S,Erten N,Karan MA

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Few studies have explored the activity levels of hospitalised older people and the intra-daily activity patterns in this group have not been described. AIMS:To describe the quantity and daily pattern of physical activity among hospitalised older people using two accelerometers: the ankle-worn StepWatch Acti...

journal_title：Aging clinical and experimental research

authors： Lim SER,Dodds R,Bacon D,Sayer AA,Roberts HC

更新日期：2018-11-01 00:00:00

abstract：AIM:To evaluate the role of balance and gait disorders, comorbidities and laboratory abnormalities in the occurrence of falls in an institutionalized elderly population. METHODS:We made a non-interventional, prospective, observational study in elderly institutionalized people. Comorbidities and information on treatmen...

journal_title：Aging clinical and experimental research

authors： Peláez VC,Ausín L,Mambrilla MR,Gonzalez-Sagrado M,Pérez Castrillón JL

更新日期：2015-08-01 00:00:00

abstract：:The current trend toward an ever increasing aging population forces society to face the problem of how to care for elderly people who are exposed to the risk of so-called "elder abuse," a phenomenon becoming increasingly widespread in Italy, as legislation does not provide a precise juridical definition of "elderly" n...

journal_title：Aging clinical and experimental research

authors： Molinelli A,Viale L,Landolfa MC,De Stefano F

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Whether or not there has been a "compression of morbidity" in older ages has been vividly debated during the last decades. Previous studies have found indications of both improved and deteriorated health among elderly persons. Few studies have analyzed how changes in health indicators are influenced...

journal_title：Aging clinical and experimental research

authors： Wilhelmson K,Allebeck P,Steen B

更新日期：2002-10-01 00:00:00

abstract：:Visual identification of vertebral fractures from spinal radiographs makes use of operator expertise in ruling out non-fracture deformities or normal variants. Morphometric X-ray absorptiometry (MXA) has recently been developed to assess vertebral deformity status quantitatively by dual energy X-ray absorptiometry (DX...

journal_title：Aging clinical and experimental research

authors： Francucci CM,Romagni P,Fiscaletti P,Caudarella R,Boscaro M

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) research progress is impeded due to participant recruitment challenges. This study seeks to better understand, from the perspective of individuals engaged in clinical trials (CTs), research motivations. METHODS:Participants, or their caregivers, from AD treatment and prevention CTs ...

journal_title：Aging clinical and experimental research

authors： Bardach SH,Holmes SD,Jicha GA

更新日期：2018-02-01 00:00:00

abstract：:Risk for or established malnutrition is frequent in older adults, accompanied by functional limitations, increased morbidity and mortality. Protein-energy malnutrition is often observed and leads besides other predisposing factors to sarcopenia, the increased loss of muscle mass with aging. Sarcopenia is an integral c...

journal_title：Aging clinical and experimental research

authors： Sieber CC

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Oxidative stress has been considered one of the causes of aging. For this reason, treatments based on antioxidants or those capable of increasing endogenous antioxidant activity have been taken into consideration to delay aging or age-related disease progression. AIM:In this paper, we determine if resveratr...

journal_title：Aging clinical and experimental research

authors： Tung BT,Rodriguez-Bies E,Thanh HN,Le-Thi-Thu H,Navas P,Sanchez VM,López-Lluch G

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND AND AIMS:In Italy there is a paucity of empirical data on practices concerning end-of-life decisions (ELDs) in geriatrics. We aimed to investigate the frequency and characteristics of ELDs made by Italian physicians and nurses in the geriatric setting. METHODS:In 2009, an anonymous questionnaire was sent to...

journal_title：Aging clinical and experimental research

authors： Giantin V,Siviero P,Simonato M,Iasevoli M,Pengo V,Andrigo M,Storti M,Valentini E,Pegoraro R,Maggi S,Crepaldi G,Manzato E

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:The Short Physical Performance Battery (SPPB) and the De Morton Mobility Index (DEMMI) are two commonly used instruments to assess mobility in older patients. AIMS:To compare the two assessments in acute senior trauma patients with regard to sensitivity to change during an acute care, and prediction of disc...

journal_title：Aging clinical and experimental research

authors： Gazzotti A,Meyer U,Freystaetter G,Palzer M,Theiler R,Abderhalden L,Bischoff-Ferrari HA

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND AND AIMS:The aim of this study was to investigate superoxide dismutase (SOD) activity together with malondialdehyde (MDA) levels in a group of Chinese patients with age-related macular degeneration (AMD). METHODS:Serum SOD activity and MDA levels were analysed in 56 AMD patients with subtypes (early dry, ge...

journal_title：Aging clinical and experimental research

authors： Jia L,Dong Y,Yang H,Pan X,Fan R,Zhai L

更新日期：2011-08-01 00:00:00

abstract：:Finding a biomarker of long length-of-stay (LOS) would provide a simple solution to target frail older inpatients at such risk. The aim of this study was to determine whether serum 25-hydroxyvitamin D (25OHD) deficiency, defined as serum concentration <25 nmol/L, was associated with long LOS among inpatients admitted ...

journal_title：Aging clinical and experimental research

authors： Beauchet O,Launay CP,Maunoury F,de Decker L,Fantino B,Annweiler C

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To determine the association between the level of nutritional risk and the mortality of hospitalized patients with atrial fibrillation. METHODS:In a prospective cohort study, we included patients hospitalized with atrial fibrillation in an internal medicine department in 2007. We calculated the nutritional r...

journal_title：Aging clinical and experimental research

authors： Díez-Manglano J,Clemente-Sarasa C

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The role played by cognitive reserve for the maintenance of numeracy skills in late adulthood is still not sufficiently explored. AIMS:This study mainly investigated whether cognitive reserve (i.e., vocabulary) mediates on the relationship between non-verbal reasoning and addition and multiplication skills ...

journal_title：Aging clinical and experimental research

authors： Mulas I,Ruiu M,Fastame MC

更新日期：2020-06-18 00:00:00

abstract：:Neoplastic diseases may be complicated by rheumatic diseases or may be occur with them. Dermatomyositis/polymyositis and polymyalgia rheumatica are described as paraneoplastic syndromes. We report a case with proximal muscular weakness as only symptom of colon cancer in the absence of other symptoms and laboratory abn...

journal_title：Aging clinical and experimental research

authors： Rosa F,Ferrari M,Buschiazzo A,Lanfranco E

更新日期：2013-05-01 00:00:00