Abstract:
:Osseointegration is a term that refers to the formation of a direct interface between an implant and bone without intervening soft tissue. Cementless femoral fixation in total hip arthroplasty is dependent on mechanical and biological factors that affect implant stability and long-term outcome. Osteoporosis leads to morphological and biological alterations in the proximal femur that adversely affect both mechanical stability of implant and biological response of bone, making it more challenging to achieve a valid osseointegration.
journal_name
Aging Clin Exp Resjournal_title
Aging clinical and experimental researchauthors
Piarulli G,Rossi A,Zatti Gdoi
10.1007/s40520-013-0103-0subject
Has Abstractpub_date
2013-10-01 00:00:00pages
S59-60eissn
1594-0667issn
1720-8319journal_volume
25 Suppl 1pub_type
杂志文章abstract:BACKGROUND:Higher age is associated with reduced physical capability in the general population. The role of age and gender for physical performance in older adults who exercises regularly is, however, not clear, and there is also a lack of recommendations for outcomes to address physical performance for this population...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-019-01190-x
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND AND AIMS:Older adults' ever-improving health and changing lifestyles necessitate the development of a scale that can better measure their competence at a higher level. We developed the Japan Science and Technology Agency Index of Competence (JST-IC) via item analysis and assessed its psychometric properties....
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-017-0786-8
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:There is a high burden of antipsychotic use in residential aged care facilities (RACFs) and there is concern regarding potential inappropriate prescribing of antipsychotics in response to mild behavioural symptoms. Antipsychotic use has been associated with a higher risk of mortality in community-dwelling ol...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-020-01518-y
更新日期:2020-03-11 00:00:00
abstract:OBJECTIVE:Given the impact of recurrent falls in older people, risk evaluation for falling is an important part of geriatric assessment. Available clinical tools usually do not include patients' self-perceived risk of falling. The objective of this study was to evaluate association with and predictive capacity of self-...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-013-0130-x
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND AND AIMS:Atrial fibrillation (AF) is the most frequent arrhythmia in elderly patients. Aims of this study were to evaluate the predictors of arterial stiffness after external cardioversion (ECV) of AF and to establish whether a link exists between vascular properties and left atrial diameter (LAD). METHODS:...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-013-0173-z
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:Given the progressive demographic ageing of the population and the National Health System reforms affecting care at the bedside, a periodic re-evaluation of in-hospital mortality rates and associated factors is recommended. AIMS:To describe the occurrence of in-hospital mortality among patients admitted to ...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,多中心研究
doi:10.1007/s40520-016-0576-8
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:The palliative prognostic index (PPI) is a commonly used tool to predict the life expectancy in palliative care patients. However, there is no universal cutoff, and the accuracy of different cutoffs varies. Therefore, we conducted this meta-analysis to explore the validity and accuracy of different PPI score...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,meta分析
doi:10.1007/s40520-018-0928-7
更新日期:2018-12-01 00:00:00
abstract::Osteoporosis can significantly impact on the risk of developing a fracture. Thus, fragility fractures represent a challenge for health professionals and decision makers of the twenty-first century. The aim of this work is to review the literature concerning osteoporotic fractures in Italy in terms of incidence, rate o...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,评审
doi:10.1007/s40520-013-0071-4
更新日期:2013-10-01 00:00:00
abstract::Most visual and cognitive functions are affected by aging over the lifespan. In this study, our aim was to investigate the loss in sensitivity to different classes of second-order stimuli-a class of stimuli supposed to be mainly processed in extrastriate cortex-in the aging population. These stimuli will then allow on...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-018-1018-6
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND AND AIMS:The aim of the present study is to describe the effects of aging on various cognitive domains (global cognitive function, executive function, motor speed) in a population sample of elderly men, and to describe how their age-related changes are influenced by education, depression, or prevalent cerebr...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324624
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:Alzheimer's disease (AD) research progress is impeded due to participant recruitment challenges. This study seeks to better understand, from the perspective of individuals engaged in clinical trials (CTs), research motivations. METHODS:Participants, or their caregivers, from AD treatment and prevention CTs ...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-017-0771-2
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND AND AIMS:In response to surgical stress, the body reacts with a change in metabolism to a catabolic state. This is further aggravated by the fasting state preoperatively. We aimed to determine the effects on catabolism i.e., body composition and IGF-I bioavailability as measured by the serum IGF-I/IGFBP-1 ra...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,随机对照试验
doi:10.1007/BF03325216
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND AND AIMS:Hip and knee replacements have become increasingly common in the older population but the prevalence of these procedures and the potential impact on functioning towards the end of life have not been previously described. The aim of this study was to estimate the rates and distribution of hip and kne...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324481
更新日期:2003-02-01 00:00:00
abstract:BACKGROUND:Identification of predictive factors on institutionalization provides the basis for the development and application of preadmission assessment. There is a lack of evidence for predictors of institutionalization for older people. AIMS:To examine the effect of predictive factors on institutionalization in hom...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,收录出版
doi:10.1007/s40520-016-0722-3
更新日期:2017-06-01 00:00:00
abstract::The patient, a 79-year-old woman with a history of osteoporosis, presented with acute back pain without trauma, three years ago. Spinal X rays showed a vertebral compression fracture at T7, and DXA indicated a T-score of -2.65 BMD at the total hip. The patient started treatment with alendronate 70 mg once a week, plus...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND AND AIMS:Peptydil prolyl cis-trans isomerase (PIN-1), which specifically regulates the conformational changes following phosphorylation of several proteins, targets the inactive hyper-phosphorylated tau on the Thr231-Pro motif and directly restores its biological function. Interestingly, PIN-1 is oxidatively...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324722
更新日期:2007-10-01 00:00:00
abstract::Depression is one of the leading causes of suffering in the elderly, but it is often under-diagnosed and under-treated, partly due to the false belief that depression is a common aspect of aging. Depression in the elderly is frequently comorbid with medical illnesses, may often be expressed by somatic complaints, and ...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,评审
doi:10.1007/BF03327382
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND AND AIMS:Declines in hamstrings and quadriceps maximal and rapid strength are commonly reported as a consequence of aging; however, few studies have investigated the influence of age on maximal and rapid hamstrings to quadriceps (H/Q) strength ratios. This study aimed to examine the effects of age on leg ext...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-017-0734-7
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND/AIM:Polypharmacy and inappropriate medication use in older adults is a major public health problem associated with morbidity and mortality. Aging is associated with metabolic changes and decreased drug clearance, increased drug-drug interactions, prescribing cascades, and potentially inappropriate medication...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-019-01239-x
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND AND AIMS:Osteoporosis and fall fractures are increasing problems amongst the elderly. The aim of this study was to explore whether combined population-based and individual interventions directed at risk factors for osteoporosis and falls result in behavioral changes in an elderly population. METHODS:A quasi...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324654
更新日期:2006-06-01 00:00:00
abstract::Physical frailty (PF) and sarcopenia are major health issues in geriatric populations, given their high prevalence and association with several adverse outcomes. Nevertheless, the lack of an univocal operational definition for the two conditions has so far hampered their clinical implementation. Existing definitional ...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,评审
doi:10.1007/s40520-016-0708-1
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND AND AIMS:Dehydration is the most common fluid or electrolyte disorder among older persons. This study was designed to examine the hydration status of community-dwelling seniors. METHODS:Blood and urine samples were collected from 67 independently living volunteers (65-93 yrs) who had functional limitations ...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,多中心研究
doi:10.1007/BF03324513
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:It is unclear whether motor-cognitive dual tasks predict cognitive decline better than either motor or cognitive tasks alone. AIMS:To examine the utility of the novel motor-cognitive dual-task test [Stepping Trail Making Test (S-TMT)], as a predictor of cognitive decline, and compare its predictive performa...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-020-01714-w
更新日期:2020-09-23 00:00:00
abstract:BACKGROUND AND AIMS:Despite evidence of cognitive impairment and difficulties in performing daily activities among elderly people with major depression, studies implementing objective performance-based evaluation of functional deficits in this patient population are scarce. With the aid of a computerized device we exam...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324787
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Choroidal endothelial dysfunction plays key role in wet-type age-related macular degeneration (AMD). Peripheral vascular endothelial function is not known in wet AMD. OBJECTIVE:We aimed to analyze peripheral vascular endothelial function in cases with wet-type age-related macular degeneration by measuring f...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-015-0377-5
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND AND AIMS:Walking is the core physical activity of older persons. The assessment of walking capacity is increasingly important for clinical purposes and clinical research. Differences between assessment tools and protocols for short walks to obtain gait characteristics can be responsible for changes, e.g., in...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-020-01703-z
更新日期:2020-09-15 00:00:00
abstract:BACKGROUND:The role played by cognitive reserve for the maintenance of numeracy skills in late adulthood is still not sufficiently explored. AIMS:This study mainly investigated whether cognitive reserve (i.e., vocabulary) mediates on the relationship between non-verbal reasoning and addition and multiplication skills ...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-020-01632-x
更新日期:2020-06-18 00:00:00
abstract:BACKGROUND AND AIMS:Age-related structural alterations in motor units and consequential functional manifestations are asserted to underlie the decline in the ability to finely grade, or control, muscular force in upper extremity musculature of older adults. Functional activities requiring appropriately graded muscular ...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324415
更新日期:2002-02-01 00:00:00
abstract:BACKGROUND:Malnutrition and poor physical performance are both conditions that increase in prevalence with age; however, their interrelation in a clinically relevant population has not been thoroughly studied. AIMS:This study aimed to determine the strength of the association between malnutrition and measures of both ...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-019-01295-3
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND AND AIMS:The primary aim of the present study was to examine whether there is an association between blood pressure and the risk of subsequent cognitive decline in the oldest old. Various factors associated with blood pressure and cognitive function were considered. METHODS:The study comprised 599 individua...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03325209
更新日期:2007-02-01 00:00:00