Abstract:
BACKGROUND AND AIMS:In response to surgical stress, the body reacts with a change in metabolism to a catabolic state. This is further aggravated by the fasting state preoperatively. We aimed to determine the effects on catabolism i.e., body composition and IGF-I bioavailability as measured by the serum IGF-I/IGFBP-1 ratio, of a carbohydrate rich drink given shortly before surgery. METHODS:Twenty-nine patients scheduled for a total hip replacement (THR) were randomized in a double-blind placebo-controlled pilot study to a carbohydrate-rich drink or to placebo pre-operatively. The nutritional supplementation consisted of an iso-osmolar carbohydrate-rich drink (12.5 g carbohydrates/100 ml, pH 5.0). Fasting blood samples were collected before surgery and repeated after 5 days and after 2 months. IGF-I and IGFBP-1 were determined in serum by RIA. Body composition was determined by dual energy X-ray absorptiometry (DXA). RESULTS:Compared with placebo we found a relative increase in IGF-I bioavailability post-operatively after a carbohydrate-rich drink given shortly before surgery. There were no significant longterm differences in the changes in fat or lean body mass between groups, but, in a subgroup with late scheduled surgery, there was a tendency to a difference (p=0.08) of fat loss after 2 months, with less fat loss in those who received another carbohydrate drink close to surgery. The pre-operative intake of a 200-200 x 2 ml carbohydrate drink was well tolerated and safe. There were no adverse events such as pulmonary aspiration before, during or after operation. CONCLUSIONS:A carbohydrate- rich drink given shortly before surgery increases IGF-I bioavailability post-operatively in patients undergoing a THR, but has no significant effects on body composition after 2 months in physically active people. We suggest that, if the operation is postponed for more than four hours on the same day, an additional carbohydrate drink should be given.
journal_name
Aging Clin Exp Resjournal_title
Aging clinical and experimental researchauthors
Aronsson A,Al-Ani NA,Brismar K,Hedström Mdoi
10.1007/BF03325216subject
Has Abstractpub_date
2009-04-01 00:00:00pages
97-101issue
2eissn
1594-0667issn
1720-8319pii
6261journal_volume
21pub_type
杂志文章,随机对照试验abstract:BACKGROUND AND AIMS:Impairment in visual-spatial attention can cause difficulties in planning and guiding movements, leading to falls in older adults .The purpose of this study was to investigate the relationship between visual-spatial attention during movement and the risk of falling in older adults. METHODS:Thirty-s...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03325266
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abstract:BACKGROUND:The Short Physical Performance Battery (SPPB) and the De Morton Mobility Index (DEMMI) are two commonly used instruments to assess mobility in older patients. AIMS:To compare the two assessments in acute senior trauma patients with regard to sensitivity to change during an acute care, and prediction of disc...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-019-01249-9
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journal_title:Aging clinical and experimental research
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abstract:BACKGROUND AND AIMS:Dehydration is the most common fluid or electrolyte disorder among older persons. This study was designed to examine the hydration status of community-dwelling seniors. METHODS:Blood and urine samples were collected from 67 independently living volunteers (65-93 yrs) who had functional limitations ...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,多中心研究
doi:10.1007/BF03324513
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journal_title:Aging clinical and experimental research
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doi:10.1007/s40520-018-1087-6
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journal_title:Aging clinical and experimental research
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doi:10.1007/s40520-015-0423-3
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abstract:OBJECTIVES:The objective of this article is to review the literature regarding the effectiveness and safety of Nordic walking (NW) in therapeutic rehabilitation in patients of an advanced age. METHODS:Randomized studies comparing NW with different patterns of long-lasting physical rehabilitation in older adults (avera...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,评审
doi:10.1007/s40520-016-0531-8
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-013-0010-4
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
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abstract:BACKGROUND:Frailty assessment has acquired an increasing importance in recent years and it has been demonstrated that this vulnerable profile predisposes elderly patients to a worse outcome after surgery. Therefore, it becomes paramount to perform an accurate stratification of surgical risk in elderly undergoing emerge...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-020-01735-5
更新日期:2020-11-18 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-017-0746-3
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Physical exercise and nutrition seem to have a key role in the management of hip fracture patients. AIM:To evaluate the impact of a 2-month rehabilitative protocol combined with dietetic counseling, with or without essential amino acid supplementation, on functioning in hip fracture patients. METHODS:In th...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s40520-018-1090-y
更新日期:2019-10-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:
更新日期:2002-06-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-015-0507-0
更新日期:2016-12-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324584
更新日期:2005-04-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-017-0866-9
更新日期:2018-04-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-013-0103-0
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
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更新日期:2015-06-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章,评审
doi:
更新日期:2011-04-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
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更新日期:2020-06-27 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章,随机对照试验
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更新日期:2020-04-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章,meta分析
doi:10.1007/s40520-013-0125-7
更新日期:2014-02-01 00:00:00
abstract::The occurrence of a given disease in a population is measured by prevalence and incidence. Prevalence reflects the burden of a given disease in a specific population and is calculated as point prevalence or period prevalence. Incidence denotes the number of new cases of a given disease which occur in a cohort of indiv...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章,评审
doi:10.1007/BF03325157
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Fall-induced deaths of elderly people are a major problem. AIM AND METHODS:Using the Official Cause-of-Death Statistics of Finland, we aimed to determine the current trends in the number and age-adjusted incidence (per 100,000 persons) of fall deaths among older Finns by taking into account 50 years or olde...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-018-0898-9
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Aging has several effects on auditory processing with the most important effect known as speech perception impairment in noise. AIMS:The aim of the present study was to investigate the effects of aging on spatial hearing using quick speech in noise (QSIN) and binaural masking level difference (BMLD) tests a...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
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更新日期:2020-04-01 00:00:00
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journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/BF03324508
更新日期:2003-06-01 00:00:00
abstract:BACKGROUND AND AIM:Several measurements were taken for frailty classification in geriatric population. "Frailty index" is based on "deficits in health," but it is still not available in Italian version. Thus, the aim of the present work was to validate a version of "frailty index" for the Italian geriatric community. ...
journal_title:Aging clinical and experimental research
pub_type: 杂志文章
doi:10.1007/s40520-017-0793-9
更新日期:2017-10-01 00:00:00