Accumulation of 111In-bleomycin in metastatic lesions from carcinoma of the uterine cervix and the ovary.

abstract：:The mucinous-like carcinoma-associated antigen (MCA), a new tumour marker, was dosed in 150 serous effusions. The levels of MCA were measured by means of an enzyme immunoassay (EIA). Ninety-seven were pleural effusions, 49 were peritoneal effusions and 4 were pericardial effusions. Thirty-five effusions were caused by...

journal_title：Oncology

authors： Cappellari A,Bagarella M,Olivati S,Corradi G

更新日期：1992-01-01 00:00:00

abstract：:The Abelson-virus-induced murine lymphosarcoma cell line RAW117-P and its in vivo selected highly malignant and metastatic variant RAW117-H10 have been studied for their growth in vivo, in vitro and in semi-solid agar. The highly malignant metastatic variant RAW117-H10 cells killed syngeneic Balb/c mice rapidly and fo...

journal_title：Oncology

authors： Joshi SS,Sharp JG,Brunson KW

更新日期：1987-01-01 00:00:00

abstract：:Capecitabine is converted to 5-fluorouracil by thymidine phosphorylase, and mitomycin C is capable of upregulating the expression of thymidine phosphorylase suggesting a synergistic effect. Fifty-three patients (median age 62 years) with anthracycline- and taxane-resistant, metastatic breast cancer received mitomycin ...

journal_title：Oncology

authors： Massacesi C,La Cesa A,Marcucci F,Pilone A,Rocchi MB,Zepponi L,Santini D,Tonini G,Burattini L

更新日期：2006-01-01 00:00:00

abstract：:In order to assess the feasibility of a sequential hormonal treatment after tamoxifen failure, 24 postmenopausal advanced breast cancer patients (median age 60 years; ECOG PS < or = 1) were treated with formestane (4-hydroxyandrostenedione) 250 mg i.m. fortnightly; 19 patients were estrogen receptor-positive. The site...

journal_title：Oncology

authors： Noberasco C,Bajetta E,Zilembo N,Di Leo A,Cappuzzo F,Bartoli C,Bono A,Bichisao E

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Previous data showed that distant metastatic breast cancer (MBC) might be curable in up to 3% of the cases in selected patients, mostly young, with good performance status and with low-volume metastatic disease, mainly by an aggressive multidisciplinary approach including aggressive combination chemotherapy ...

journal_title：Oncology

authors： Güth U,Elfgen C,Montagna G,Schmid SM

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Neoadjuvant chemotherapy (NAC) has become prevalent in esophageal squamous cell carcinoma (ESCC), but its long-term prognostic advantages remain unclear. The latest prognostic outcomes in clinical Stage (cStage) II/III ESCC with NAC were herein elucidated. PATIENTS AND METHODS:NAC prior to curative treatmen...

journal_title：Oncology

authors： Yamashita K,Hosoda K,Moriya H,Katada C,Sugawara M,Mieno H,Komori S,Katada N,Watanabe M

更新日期：2017-01-01 00:00:00

abstract：:The effects of theophylline treatment on mouse B-16 melanoma cell growth, metabolism, and membrane antigen expression in vitro were studied. Theophylline treatment inhibited DNA synthesis and the cell growth rate, and caused an elevation of intracellular cAMP levels. Cells treated with theophylline became elongated an...

journal_title：Oncology

authors： Kolb CA,Mansfield JM

更新日期：1980-01-01 00:00:00

abstract：:The report describes the lethal exitus of a 44-year-old woman after repeated criminal poisoning with N-nitrosodimethylamine. She died 32 months following the initial symptoms and developed a liver cirrhosis with multiple bleeding, a hemolytic syndrome and diabetes mellitus. ...

journal_title：Oncology

authors： Fussgaenger RD,Ditschuneit H

更新日期：1980-01-01 00:00:00

abstract：:In order to determine the operative indications of three-field lymph node dissection of esophageal cancer, attempts were made to collect data concerning procedures performed between 1983 and 1989 in major institutions in Japan, and the results from institutions performing three-field or two-field lymph node dissection...

journal_title：Oncology

authors： Isono K,Sato H,Nakayama K

更新日期：1991-01-01 00:00:00

abstract：:We report a rare case of a patient with an intrasplenic malignant fibrous histiocytoma (MFH) and chronic myelogenous leukemia. The neoplasms were synchronous in their onset and evolution. The peculiarity of the primary site of the MFH, the genetic implications of multiple primary tumors in a single patient, and the co...

journal_title：Oncology

authors： Bonilla F,Provencio M,Fernandez E,España P

更新日期：1994-09-01 00:00:00

abstract：:Methyl-CCNU (NSC-95441) was administered to patients with malignant melanoma in a split dose schedule. Nausea and vomiting were eliminated as clinical problems during therapy. Response rate to the drug seemed somewhat lower than the average of three previously reported disease-oriented phase II trials, though the diff...

journal_title：Oncology

authors： Wittes RE,Hong WK,Gatchell L,Krakoff IH,Golbey RB

更新日期：1977-01-01 00:00:00

abstract：:Thrombopoietin (TPO) is a recently discovered hematopoietic growth factor which stimulates the production and maturation of megakaryocytes. In this study, we used a modified MTT assay to examine the in vitro growth-stimulatory effects of recombinant human (rh) TPO and recombinant human stem cell factor (rhSCF) on eigh...

journal_title：Oncology

authors： Shinohara A,Shimizu E,Takada M,Sone S

更新日期：1996-09-01 00:00:00

abstract：:Repeated ultraviolet light (UV) irradiation on the skin of rats caused ulceration, scarring and epithelial tumors; 38% of the animals had ear tumors and 5% skin tumors. Guinea pigs presented minimal evidence of neoplastic transformation; only two tumors were seen while hamsters displayed localized epidermal hyperplasi...

journal_title：Oncology

authors： Stenbäck F

更新日期：1975-01-01 00:00:00

abstract：OBJECTIVE:Serrated adenoma (SA) consists of glands both with intraluminal projection of tall columnar cells, which resemble the terminally differentiated cells in the surface epithelium, and with concave short cells, which resemble progenitor crypt cells of the colon. The aim of this study was to clarify the relationsh...

journal_title：Oncology

authors： Jiao YF,Nakamura S,Sugai T,Yamada N,Habano W

更新日期：2008-01-01 00:00:00

abstract：:Magnetic resonance imaging-guided laser interstitial thermal therapy (LITT) is a minimally invasive treatment modality with recent increasing use to ablate brain tumors. When originally introduced in the late 1980s, the inability to precisely monitor and control the thermal ablation limited the adoption of LITT in neu...

journal_title：Oncology

authors： Rahmathulla G,Recinos PF,Kamian K,Mohammadi AM,Ahluwalia MS,Barnett GH

更新日期：2014-01-01 00:00:00

abstract：:The purpose of this study was to evaluate in a dog model whether intrapericardial instillation of tetracycline is superior to the effect of drainage alone in causing pericardial adhesions and cavity obliteration. Twelve mongrel dogs were randomly divided into two experimental groups. All dogs received a pericardial dr...

journal_title：Oncology

authors： Markiewicz W,Ben-Arieh Y,Best L,Mordochovich D,Rinkevitch D

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:There has been no clinically useful diagnostic or prognostic biomarker for renal cell carcinoma (RCC). Serum γ-glutamyltransferase (GGT) activity has been reported to be a prognostic marker for several types of cancer including RCC. Exosomes or small extracellular vesicles present in body fluids have potenti...

journal_title：Oncology

authors： Horie K,Kawakami K,Fujita Y,Matsuda Y,Arai T,Suzui N,Miyazaki T,Koie T,Mizutani K,Ito M

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES AND METHODS:The association oxaliplatin (OXA)-5-fluorouracil/folinic acid (FUFA) is currently a standard first-line treatment for advanced colorectal cancer. The main objective of this experimental study was to examine the cytotoxic effects resulting from the addition of ionizing radiation (Rgamma) to the co...

journal_title：Oncology

authors： Magné N,Fischel JL,Formento P,Etienne MC,Dubreuil A,Marcié S,Lagrange JL,Milano G

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:It is unclear for whom new anti-human epidermal growth factor receptor 2 (anti-HER2) agents, such as pertuzumab and T-DM1, should be considered. We investigated prognostic factors before neoadjuvant chemotherapy (NAC) among HER2-positive invasive breast cancer patients and those after NAC among patients who ...

journal_title：Oncology

authors： Fujita N,Enomoto Y,Inakami K,Yanagisawa T,Iguchi C,Aono T,Nomura T,Yamamoto H,Kasugai T,Shiba E

更新日期：2020-01-01 00:00:00

abstract：:We evaluated changes in serum albumin concentrations in 15 patients with advanced malignancy who were also receiving cisplatin. All 15 patients had serial measurements of serum albumin. The decrease in serum albumin from the time of the first dose of cisplatin to death correlated with liver platinum levels at autopsy ...

journal_title：Oncology

authors： Nanji AA,Mikhael NZ,Stewart DJ

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess the use of 5-fluorouracil (5-FU), leucovorin and oxaliplatin (FOLFOX) regimens in clinical practice according to their efficacy and toxicity. METHODS:Patients who received oxaliplatin-containing regimens after curative resection for colorectal carcinoma from 10 different o...

journal_title：Oncology

authors： Uncu D,Aksoy S,Çetin B,Yetişyiğit T,Özdemir N,Berk V,Dane F,Inal A,Harputluoğlu H,Budakoğlu B,Koca D,Sevinç A,Cihan S,Durnalı AG,Özkan M,Öztürk MA,Işıkdoğan A,Büyükberber S,Benekli M,Köş T,Alkış N,Karaca H,Tur

更新日期：2013-01-01 00:00:00

abstract：:The role of estrogen and estrogen-related growth factors in the mechanism of hormone dependency of endometrial adenocarcinoma cells was investigated. The proliferation of hormone-responsive human endometrial adenocarcinoma cells (Ishikawa cells), which possess both estrogen and progesterone receptors, was optimally st...

journal_title：Oncology

authors： Hata H,Hamano M,Watanabe J,Kuramoto H

更新日期：1998-12-01 00:00:00

abstract：:Fifteen patients, median age 64 years, presenting with advanced gastrointestinal adenocarcinomas, were included in this study. The treatment combination consisted of folinic acid (200 mg/m2, IV bolus injection) followed by 5-fluorouracil (5-FU; 400 mg/m2, 30-min infusion) for 5 consecutive days and mitomycin C (10 mg/...

journal_title：Oncology

authors： Becouarn Y,Brunet R,Bussières E,Marée D

更新日期：1988-01-01 00:00:00

abstract：:An immunohistochemical stain to the c-ErbB-2 protein was performed in 225 paraffin-embedded tissue blocks from patients with locally advanced gastric cancer who underwent curative resection. The overexpression of the c-ErbB-2 protein was observed in 27.4% of the patients. The c-ErbB-2 positivity showed a statistically...

journal_title：Oncology

authors： Lee HR,Kim JH,Uhm HD,Ahn JB,Rha SY,Cho JY,Lee JI,Lee KH,Chung HC,Roh JK,Min JS,Lee KS,Shin DH,Kim BS,Hong SW,Choi JH

更新日期：1996-05-01 00:00:00

abstract：:This is a phase II study to evaluate the efficacy and toxicity of short-course carboplatin in advanced-stage nasopharyngeal carcinoma (NPC). Thirty-three previously untreated stage III-IV NPC patients were studied. Carboplatin was given as a rapid intravenous injection every 3 weeks. The dose of carboplatin was calcul...

journal_title：Oncology

authors： Chi KH,Chang YC,Chan WK,Liu JM,Law CK,Lo SS,Shu CH,Yen SH,Whang-Peng J,Chen KY

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:This pharmacokinetic study of S-1 was conducted in patients in whom glomerular filtration rate (GFR) was directly measured to explore the possibility of adjusting the S-1 dose on the basis of GFR in patients with normal or nearly normal renal function. METHODS:S-1 was given to 12 patients twice daily for 28 ...

journal_title：Oncology

authors： Ando Y,Kawada K,Inada M,Morita S,Mitsuma A,Yasuda Y,Hiramatsu M,Fujimoto Y,Fujita K

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Wernicke's encephalopathy (WE) is a neurological emergency which presents with symptoms of confusion, ophthalmoplegia, and ataxia. Cancer patients are at high risk of this acute encephalopathy due to chronic malnutrition, chemotherapy-induced nausea and vomiting, and consumption of thiamine by rapidly growin...

journal_title：Oncology

authors： Kuo SH,Debnam JM,Fuller GN,de Groot J

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:We evaluated the efficacy and safety of bolus 5-fluorouracil (5-FU) and leucovorin combined with weekly paclitaxel (FLTAX) in advanced gastric cancer (GC) patients. METHODS:Patients with untreated stage IV GC received paclitaxel 80 mg/m(2) as a 1-hour infusion, followed by 5-FU 600 mg/m(2) as a bolus infusio...

journal_title：Oncology

authors： Matsubara J,Shimada Y,Kato K,Nagai Y,Iwasa S,Nakajima TE,Hamaguchi T,Yamada Y,Takagi S,Kobayashi K,Yoshioka A,Nakayama N,Tsuji A

更新日期：2011-01-01 00:00:00

abstract：:A multidrug-resistant (MDR) cell line isolated from HOB1 lymphoma cells was characterized. The MDR phenotype in this cell line was typified by resistance to vincristine with varying degrees of cross-resistance to Adriamycin, colcemid and actinomycin D. Decreased intracellular [3H]vincristine with concurrent increase i...

journal_title：Oncology

authors： Lee WP,Lee CL

更新日期：1994-01-01 00:00:00

abstract：:Objective tumor responses and survival rates with standard chemotherapy options for small-cell lung cancer (SCLC) and non-small-cell lung cancer (NSCLC) have been disappointing. However, several promising new classes of agents have emerged in recent years, including the taxanes, mitotic spindle inhibitors, antimetabol...

journal_title：Oncology

authors： Huang CH,Treat J

更新日期：2001-01-01 00:00:00