Lethal exitus of a patient with N-nitrosodimethylamine poisoning, 2.5 years following the first ingestion and signs of intoxication.

abstract：OBJECTIVE:This pharmacokinetic study of S-1 was conducted in patients in whom glomerular filtration rate (GFR) was directly measured to explore the possibility of adjusting the S-1 dose on the basis of GFR in patients with normal or nearly normal renal function. METHODS:S-1 was given to 12 patients twice daily for 28 ...

journal_title：Oncology

authors： Ando Y,Kawada K,Inada M,Morita S,Mitsuma A,Yasuda Y,Hiramatsu M,Fujimoto Y,Fujita K

更新日期：2012-01-01 00:00:00

abstract：:CA 19-9 and tissue polypeptide antigen (TPA) were determined in the sera of 28 control subjects, 29 patients with pancreatic cancer, 26 with chronic pancreatitis and 62 with benign and malignant extra pancreatic diseases in order to compare their usefulness in diagnosing pancreatic cancer, to verify whether the combin...

journal_title：Oncology

authors： Basso D,Fabris C,Del Favero G,Panucci A,Plebani M,Angonese C,Leandro G,Dodi G,Burlina A,Naccarato R

更新日期：1988-01-01 00:00:00

abstract：:Malignant gastrointestinal neuroectodermal tumor (GNET) is an aggressive rare tumor, primarily occurring in young adults with frequent local-regional metastases and recurrence after local control. The tumor is characterized by the presence of EWSR1-ATF1 or EWSR1-CREB1 and immunohistochemical positivity for S-100 prote...

journal_title：Oncology

authors： Subbiah V,Holmes O,Gowen K,Spritz D,Amini B,Wang WL,Schrock AB,Meric-Bernstam F,Zinner R,Piha-Paul S,Zarzour M,Elvin JA,Erlich RL,Stockman DL,Vergilio JA,Suh JH,Stephens PJ,Miller V,Ross JS,Ali SM

更新日期：2016-01-01 00:00:00

abstract：:The effects on gastric and duodenal mucosa induced by cisplatin plus etoposide (PE) chemotherapy were investigated in 32 patients with lung cancer. They were submitted to gastroduodenoscopy before receiving cisplatin 100 mg/m2 (day 1) plus etoposide at a mean dose of 107 mg/m2 (days 1, 3 and 5). Endoscopic examination...

journal_title：Oncology

authors： Sartori S,Nielsen I,Maestri A,Beltrami D,Trevisani L,Pazzi P

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:Expression of vascular endothelial growth factor (VEGF)-D by tumors is associated with metastasis to lymph nodes in mice. However, there are few reports concerning the clinical significance of VEGF-D protein in human carcinoma. METHODS:After confirming production of VEGF-D by eight colorectal carcinoma cell ...

journal_title：Oncology

authors： Funaki H,Nishimura G,Harada S,Ninomiya I,Terada I,Fushida S,Tani T,Fujimura T,Kayahara M,Shimizu K,Ohta T,Miwa K

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVES:Early detection of esophageal cancer is hampered by paucity of molecular markers for diagnosis of this aggressive gastrointestinal malignancy in early stages. We recently identified TC21/R-Ras2, a small GTP-binding protein (SMG) in esophageal squamous cell carcinomas (ESCCs) by differential display. This stu...

journal_title：Oncology

authors： Sharma R,Sud N,Chattopadhyay TK,Ralhan R

更新日期：2005-01-01 00:00:00

abstract：GOALS OF WORK:There is a need for an effective and nontoxic chemotherapy for palliative indication in non-Hodgkin's lymphoma (NHL) patients who relapse after conventional or high-dose chemotherapy. The aim of this study was to investigate the feasibility and efficacy of peroral chemotherapy in the palliative treatment ...

journal_title：Oncology

authors： Salminen E,Nikkanen V,Lindholm L

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Mutations in the human telomerase reverse transcriptase (hTERT) gene promoter have been reported in hepatocellular carcinoma (HCC); however, analyses of these mutations in liquid biopsies have been technically difficult because of the high GC content of the regions of interest within this promoter. We evalua...

journal_title：Oncology

authors： Ako S,Nouso K,Kinugasa H,Matsushita H,Terasawa H,Adachi T,Wada N,Takeuchi Y,Mandai M,Onishi H,Ikeda F,Shiraha H,Takaki A,Fujioka S,Mimura T,Okada H

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:We conducted this study to compare tumor measurement by computed tomography (CT) and tumor response assessment between Response Evaluation Criteria In Solid Tumors (RECIST) 1.0 and RECIST 1.1 in patients with metastatic colorectal cancer (CRC). METHODS:We reviewed the medical records of patients with metasta...

journal_title：Oncology

authors： Jang HJ,Kim BC,Kim HS,Kim JH,Song HH,Kim JB,Park JJ,Yoon SN,Woo JY,Zang DY

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:To assess whether the use of an organ-specific treatment could improve event-free survival (EFS) and overall survival as endpoints in testicular lymphoma in the early stage: IE and IIE. METHODS:Thirty-four patients were selected to be treated with orchiectomy following six cycles of anthracycline-based comb...

journal_title：Oncology

authors： Avilés A,Neri N,Huerta-Guzmán J,Pérez F,Fernández R

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:To determine the dose-limiting toxicities (DLTs) and the maximum-tolerated doses of the paclitaxel, oxaliplatin (LOHP) and capecitabine combination in patients with advanced solid tumors. PATIENTS AND METHODS:Patients received escalating doses of paclitaxel (starting dose 100 mg/m2) and LOHP (starting dose 40 ...

journal_title：Oncology

authors： Saridaki Z,Bozionelou V,Kentepozidis N,Kotsakis A,Vardakis N,Kalykaki A,Gioulbasanis I,Karampeazis A,Vamvakas L,Georgoulias V,Mavroudis D

更新日期：2007-01-01 00:00:00

abstract：:Results of a survey of concentrations of substances immunologically cross-reactive with insulin (SICRI), glucose and growth hormone in preprandially drawn blood of 84 patients suffering from bronchial epidermoid, microcellular and adenocarcinomas and 22 patients from sarcoidosis, tuberculosis and obstructive bronchiti...

journal_title：Oncology

authors： Baltić V,Levanat S,Petek M,Bratić-Mikes V,Pavelić K,Vuk-Pavlović S

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to investigate whether the Ile646Val (2073A>G) polymorphism in the kinase-binding domain of A-kinase anchoring protein 10 (AKAP10) is related to the risk of colorectal cancer (CRC), clinicopathological variables and the environmental factors for the development of CRC. METHODS:Ap...

journal_title：Oncology

authors： Wang MJ,Zhou ZG,Wang L,Yu YY,Zhang P,Zhang Y,Cui CF,Yang L,Li Y,Zhou B,Sun XF

更新日期：2009-01-01 00:00:00

abstract：:Sorafenib, an oral multikinase inhibitor, has demonstrated clinical efficacy in patients with advanced hepatocellular carcinoma (HCC). However, in the SHARP trial (Sorafenib HCC Assessment Randomized Protocol trial) and the Asia-Pacific trial (conducted in the Asia-Pacific region), no cases of complete response (CR) w...

journal_title：Oncology

authors： Inuzuka T,Nishikawa H,Sekikawa A,Takeda H,Henmi S,Sakamoto A,Saito S,Kita R,Kimura T,Osaki Y,Kudo M

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:N-Acetylglucosaminyltransferase V (GnT-V) is a key enzyme in the formation of branching asparagine-linked oligosaccharides and is linked to tumor invasion and metastasis in colon and breast cancers. In normal esophageal epithelium, beta1,6-branched asparagine-linked oligosaccharides synthesized by GnT-V are s...

journal_title：Oncology

authors： Ishibashi Y,Dosaka-Akita H,Miyoshi E,Shindoh M,Miyamoto M,Kinoshita I,Miyazaki H,Itoh T,Kondo S,Nishimura M,Taniguchi N

更新日期：2005-01-01 00:00:00

abstract：:The present communication reports data on the lipid biosynthesis of Ehrlich ascites tumor cells grown in culture media supplemented with modified sera. Whereas the metabolisms of [14C]pyruvate and [14C]mevalonate are identical in all media tested, the incorporation of [14C] acetate is higher in medium with dialyzed se...

journal_title：Oncology

authors： Löffler M,Schneider F

更新日期：1979-01-01 00:00:00

abstract：:A multidrug-resistant (MDR) cell line isolated from HOB1 lymphoma cells was characterized. The MDR phenotype in this cell line was typified by resistance to vincristine with varying degrees of cross-resistance to Adriamycin, colcemid and actinomycin D. Decreased intracellular [3H]vincristine with concurrent increase i...

journal_title：Oncology

authors： Lee WP,Lee CL

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:18F-fluorodeoxyglucose positron emission tomography (FDG-PET) is useful for differentiating benign from malignant lesions, evaluating tumor stage, monitoring the response to therapy and detecting tumor recurrence in a variety of malignancies. Nevertheless, its use in patients with hepatocellular carcinoma (H...

journal_title：Oncology

authors： Yoon KT,Kim JK,Kim DY,Ahn SH,Lee JD,Yun M,Rha SY,Chon CY,Han KH

更新日期：2007-01-01 00:00:00

abstract：:Methyl-CCNU (NSC-95441) was administered to patients with malignant melanoma in a split dose schedule. Nausea and vomiting were eliminated as clinical problems during therapy. Response rate to the drug seemed somewhat lower than the average of three previously reported disease-oriented phase II trials, though the diff...

journal_title：Oncology

authors： Wittes RE,Hong WK,Gatchell L,Krakoff IH,Golbey RB

更新日期：1977-01-01 00:00:00

abstract：:Male and female mice of strains C3H/eB and C57BL/6 were injected subcutaneously with methylcholanthrene (MCA) dissolved in olive oil; mice injected with olive oil served as controls. After intervals of from 2 to 13 weeks, experimental and control mice were injected intraperitoneally with 51Cr-labeled rat red cells (RR...

journal_title：Oncology

authors： Schrieber R,Stern K

更新日期：1984-01-01 00:00:00

abstract：:Fourteen patients with advanced ovarian carcinoma (FIGO stages III-IV) resistant to cisplatin were submitted to an alternating regimen with doxorubicin (A), cyclophosphamide (C), bleomycin (B) and mitomycin C (M). All patients had measurable disease on entry into the study. No responses were observed while 3 patients,...

journal_title：Oncology

authors： Benedetti Panici P,Scambia G,Greggi S,Salerno G,Cento R,Mancuso S

更新日期：1990-01-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) has been shown to be highly responsive to chemotherapy. The major limiting toxicity was myelotoxicity. Recently, the role of granulocyte colony-stimulating factor (G-CSF) in reducing chemotherapy-induced neutropenic sepsis has been well established. In this study, we tested whether recom...

journal_title：Oncology

authors： Wang CH,Wang HM,Chen JS,Chang WJ,Lai GM

更新日期：1997-01-01 00:00:00

abstract：:Thirteen samples of gastric tumors that had developed in the remnant stomach (remnant gastric cancer) were compared with 63 samples of primary gastric tumors located in the upper third of the stomach (primary gastric cancer) by both clinicopathologic and flow cytometric analysis. The depths of invasion of all these tu...

journal_title：Oncology

authors： Ikeguchi M,Kondou A,Oka A,Tsujitani S,Maeta M,Kaibara N

更新日期：1995-03-01 00:00:00

abstract：:We analyzed the differential gene expression in the pancreatic cancer cell line NP-18 upon induction of apoptosis caused by cyclin-dependent kinase inhibition triggered by either overexpression of the tumor suppressor gene p16(INK4A)using an adenoviral construction or incubation with the chemical inhibitors, roscoviti...

journal_title：Oncology

authors： Blasco F,Peñuelas S,Cascalló M,Hernández JL,Alemany C,Masa M,Calbó J,Soler M,Nicolás M,Pérez-Torras S,Gómez A,Tarrasón G,Noé V,Mazo A,Ciudad CJ,Piulats J

更新日期：2004-01-01 00:00:00

abstract：:The Abelson-virus-induced murine lymphosarcoma cell line RAW117-P and its in vivo selected highly malignant and metastatic variant RAW117-H10 have been studied for their growth in vivo, in vitro and in semi-solid agar. The highly malignant metastatic variant RAW117-H10 cells killed syngeneic Balb/c mice rapidly and fo...

journal_title：Oncology

authors： Joshi SS,Sharp JG,Brunson KW

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:We evaluated the efficacy and safety of bolus 5-fluorouracil (5-FU) and leucovorin combined with weekly paclitaxel (FLTAX) in advanced gastric cancer (GC) patients. METHODS:Patients with untreated stage IV GC received paclitaxel 80 mg/m(2) as a 1-hour infusion, followed by 5-FU 600 mg/m(2) as a bolus infusio...

journal_title：Oncology

authors： Matsubara J,Shimada Y,Kato K,Nagai Y,Iwasa S,Nakajima TE,Hamaguchi T,Yamada Y,Takagi S,Kobayashi K,Yoshioka A,Nakayama N,Tsuji A

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess the use of 5-fluorouracil (5-FU), leucovorin and oxaliplatin (FOLFOX) regimens in clinical practice according to their efficacy and toxicity. METHODS:Patients who received oxaliplatin-containing regimens after curative resection for colorectal carcinoma from 10 different o...

journal_title：Oncology

authors： Uncu D,Aksoy S,Çetin B,Yetişyiğit T,Özdemir N,Berk V,Dane F,Inal A,Harputluoğlu H,Budakoğlu B,Koca D,Sevinç A,Cihan S,Durnalı AG,Özkan M,Öztürk MA,Işıkdoğan A,Büyükberber S,Benekli M,Köş T,Alkış N,Karaca H,Tur

更新日期：2013-01-01 00:00:00

abstract：:The disease provoked by injections of water and other harmless liquids or wounds without tissue loss, is characterized by the regression of certain organs, opening in the epidermis, pigmentary anomalies and malignant tumors. The very few worms which recover spontaneously, regenerate the eliminated parts or develop sup...

journal_title：Oncology

authors： Chandebois R

更新日期：1975-01-01 00:00:00

abstract：PURPOSE:The well-being of oncologists is important to the well-being of their patients. While much is known about oncologist distress, little is known about oncologist well-being. We set out to evaluate oncologist well-being and the personal wellness promotion strategies used by oncologists. PATIENTS AND METHODS:We pe...

journal_title：Oncology

authors： Shanafelt TD,Novotny P,Johnson ME,Zhao X,Steensma DP,Lacy MQ,Rubin J,Sloan J

更新日期：2005-01-01 00:00:00

abstract：:Glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) were determined in 8 patients with disseminated testicular carcinoma before, during and 1 year after termination of a combination chemotherapy with cis-diamminedichloroplatinum (CDDP). The decrease in median GFR in comparison with the pretreatment...

journal_title：Oncology

authors： Meijer S,Mulder NH,Sleijfer DT,Donker AJ,Sluiter WJ,de Jong PE,Schraffordt Koops H,van der Hem GK

更新日期：1983-01-01 00:00:00