Flow cytometric analysis of the DNA content of tumor cells in cases of gastric cancer in the upper third of the stomach and in the remnant stomach.

abstract：BACKGROUND:Bladder cancer is the fifth most common cancer among men and the seventh among women. At diagnosis, at least 25% of bladder cancer tumors are locally or systemically advanced. Systemic chemotherapy is the only current modality for advanced or metastatic transitional cell carcinoma of the bladder. Recently, a...

journal_title：Oncology

authors： Adamo V,Magno C,Spitaleri G,Garipoli C,Maisano C,Alafaci E,Adamo B,Rossello R,Scandurra G,Scimone A

更新日期：2005-01-01 00:00:00

abstract：:38 of 306 patients survived beyond 5 years after resection of an exocrine pancreatic carcinoma during a period from 1971 to 1993. Amongst the long-term survivors there were 12 patients with ductal, 22 with ampullary, 3 with distal bile duct and 1 with duodenal cancer. An active operative strategy was employed in order...

journal_title：Oncology

authors： Klempnauer J,Ridder GJ,Bektas H,Pichlmayr R

更新日期：1995-09-01 00:00:00

abstract：:6 cases of endodermal sinus tumor of the ovary are presented. In 4 patients pure endodermal sinus tumor was found microscopically. 1 patient had endodermal sinus tumor in one ovary and gonadoblastoma in the contralateral one. In another case endodermal sinus tumor was accompanied by an embryonal teratoma. Histological...

journal_title：Oncology

authors： Sikorowa L,Morawski A,Piatkowski Z

更新日期：1979-01-01 00:00:00

abstract：:Antineoplastic properties of different Schiff bases obtained by the interaction of 5-nitrofuran with substituted pyrimidines have been examined both in vitro and in vivo. In vitro studies on L 5178Y/asparaginase sensitive, HL 60 and P 388 cell lines and in vivo studies on the P 388 cell line indicate that all the comp...

journal_title：Oncology

authors： Sur B,Chatterjee SP,Sur P,Maity T,Roychoudhury S

更新日期：1990-01-01 00:00:00

abstract：:58 consecutively referred, previously untreated patients with nodular lymphomas (stages III and IV) were treated with two different combination chemotherapy regimens-(cyclophosphamide, vincristine and prednisone (COP), and BCNU , cyclophosphamide, vincristine, melphalan and prednisone (M-2) - to compare remission indu...

journal_title：Oncology

authors： Case DC Jr

更新日期：1984-01-01 00:00:00

abstract：:Oral cancer is the eleventh most common cancer globally, with well-established major risk factors of tobacco, areca nut, alcohol, and high-risk human papillomavirus (HR-HPV) types 16 and 18. HR-HPV16/18 are the etiologic agents of cervical cancers and a proportion of oropharyngeal cancers. HPV-associated oropharyngeal...

journal_title：Oncology

authors： Yete S,D'Souza W,Saranath D

更新日期：2018-01-01 00:00:00

abstract：:Twenty-two patients with metastatic breast carcinoma were treated with a combination of cisplatin (100 mg/m2 i.v. day 1) and etoposide (100 mg/m2 i.v. days 1-3). Eligible patients had measurable disease with normal organ functions, performance status < 3, age < 70 years and no previous chemotherapy for metastatic dise...

journal_title：Oncology

authors： Lluch A,Azagra P,Cervantes A,Muñoz M,Alberola V,Santabarbara P,García-Conde J

更新日期：1994-07-01 00:00:00

abstract：:Twenty-seven patients with advanced measurable colorectal carcinoma were treated with a combination protocol consisting of folinic acid (FA) 200 mg/m2 i.v. bolus followed by 5-fluorouracil (5-FU) 550 mg/m2, and cisplatin (CIS) 20 mg/m2 each administered as a 2-hour i.v. infusion. Treatment was given on 4 consecutive d...

journal_title：Oncology

authors： Scheithauer W,Depisch D,Schiessel R,Ludwig H

更新日期：1989-01-01 00:00:00

abstract：:The levels of bone-specific alkaline phosphatase (BALP) in plasma and tumour tissue samples of 20 Chinese patients with osteosarcoma in Hong Kong were measured by the wheat germ lectin precipitation technique. The plasma BALP levels in these patients were significantly higher than those of the normal subjects (p < 0.0...

journal_title：Oncology

authors： Liu PP,Leung KS,Kumta SM,Lee KM,Fung KP

更新日期：1996-07-01 00:00:00

abstract：:We have measures serial carcinoembryonic antigen (CEA) titers in 92 patients, randomly selected from the patient population of a Radiotherapeutic Clinic, to correlate with clinical and follow-up evaluation. 57 out of 92 patients had positive CEA levels (2.5 ng/ml) or 62 percent of proven cancer patients. In this serie...

journal_title：Oncology

authors： Vider M,Kashmiri R,Hunter L,Moses B,Meeker WR,Utley JF,Maruyama Y

更新日期：1974-01-01 00:00:00

abstract：OBJECTIVE:To compare chemotherapy-related and total medical costs among patients with colorectal cancer (CRC) receiving capecitabine or 5-fluorouracil (5-FU) monotherapy after surgical resection. METHODS:This retrospective, claim-based study utilized the Thomson Reuters Market Scan(R) databases to identify 1,396 CRC p...

journal_title：Oncology

authors： Chu E,Shi N,Wei W,Bendell JC,Cartwright T

更新日期：2009-01-01 00:00:00

abstract：:Fourteen patients with advanced ovarian carcinoma (FIGO stages III-IV) resistant to cisplatin were submitted to an alternating regimen with doxorubicin (A), cyclophosphamide (C), bleomycin (B) and mitomycin C (M). All patients had measurable disease on entry into the study. No responses were observed while 3 patients,...

journal_title：Oncology

authors： Benedetti Panici P,Scambia G,Greggi S,Salerno G,Cento R,Mancuso S

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVES:Insulin-like growth factor I (IGF-I) and other components of the IGF system have been implicated in the etiology of several human malignancies. We have undertaken a case-control study among Greek women to explore the relation of major components of the IGF system (IGF-I, IGF-II and IGF-binding protein 3, IGF...

journal_title：Oncology

authors： Petridou E,Koukoulomatis P,Alexe DM,Voulgaris Z,Spanos E,Trichopoulos D

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:We retrospectively investigated the treatment outcomes of second-line treatment with pazopanib or gemcitabine/docetaxel in patients with advanced soft tissue sarcoma (STS). METHODS:Ninety-one patients who were treated with pazopanib or gemcitabine/docetaxel for advanced STS between 1995 and 2015 were analyz...

journal_title：Oncology

authors： Kim JH,Park HS,Heo SJ,Kim SK,Han JW,Shin KH,Kim SH,Hur H,Kim KS,Choi YD,Kim S,Lee YH,Suh JS,Ahn JB,Chung HC,Noh SH,Rha SY,Kim HS

更新日期：2019-01-01 00:00:00

abstract：:Improved understanding of tumor biology has led to the identification of numerous growth factors that are involved in malignant transformation and tumor progression. Many of these factors induce cellular responses through receptors with intrinsic tyrosine kinase (TK) activity. Therefore, inhibiting receptor TK activit...

journal_title：Oncology

authors： Baselga J,Hammond LA

更新日期：2002-01-01 00:00:00

abstract：:Calcitriol (1,25-dihydroxycholecalciferol) has antiproliferative and/or proapoptotic effects on many cell types and the glucocorticoid dexamethasone enhances these effects. We have shown that calcitriol modulates several key signaling proteins involved in differentiation, proliferation and apoptosis in tumor-derived m...

journal_title：Oncology

authors： Flynn G,Chung I,Yu WD,Romano M,Modzelewski RA,Johnson CS,Trump DL

更新日期：2006-01-01 00:00:00

abstract：:In 29 patients (48 courses of chemotherapy), a randomized double-blind crossover study was undertaken to establish the antiemetic effectiveness of a combination of metoclopramide at a moderately high dose (5 mg/kg body weight) with 1 g methylprednisolone (treatment A) as compared with metoclopramide monotherapy (5 mg/...

journal_title：Oncology

authors： Ell C,König HJ,Brockmann P,Domschke S,Domschke W

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Radioimmunotherapy (RIT) is effective in treating relapsed/refractory follicular lymphoma (FL), with durable remissions in first-line consolidation. We hypothesized that RIT with ibritumomab tiuxetan (Zevalin®) would result in durable remissions by eliminating minimal residual disease after cytoreduction. M...

journal_title：Oncology

authors： Puvvada SD,Guillén-Rodríguez JM,Yan J,Inclán L,Heard K,Rivera XI,Anwer F,Mahadevan D,Schatz JH,Persky DO

更新日期：2018-01-01 00:00:00

abstract：:Since aspirin was found to cause a persistent decrease in pyruvate kinase activity, which is a prominent characteristic of the hepatic promoters, the effect of aspirin on hepatic tumorigenesis in the rat has been studied. Male Wistar rats were initiated with a diet containing 0.06% 3'-methyl-4-dimethylamino-azobenzene...

journal_title：Oncology

authors： Yanagi S,Yamashita M,Hiasa Y

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVE:We performed a pilot study to evaluate the effect of the high-dose gemcitabine-cisplatin combination in a brief weekly regimen in the treatment of primary refractory diffuse large cell lymphoma with high or high-intermediate clinical risk. METHODS:Thirty patients refractory to first-line anthracycline-based ...

journal_title：Oncology

authors： Avilés A,Neri N,Huerta-Guzmán J,Fernández R

更新日期：2004-01-01 00:00:00

abstract：:The role of p53, retinoblastoma (RB) and c-erbB-2 gene proteins in the pathogenesis of anal carcinomas has been examined. A total of 97 patients were included in the study. c-erbB-2, RB and p53 proteins were abnormal in 0, 5 and 34% of the cases, respectively. No correlation was observed between p53 and age, sex, tumo...

journal_title：Oncology

authors： Tanum G,Holm R

更新日期：1996-09-01 00:00:00

abstract：:The expression of the drug resistance markers P glycoprotein (P-170), glutathione S transferase-pi (GST-pi) and DNA topoisomerase II (Topo II) was analyzed in 16 human kidney carcinoma cell lines, 18 hematological malignancies, and 14 human breast carcinomas. We found a tendency for coexpression of increased P-170 and...

journal_title：Oncology

authors： Efferth T,Mattern J,Volm M

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the outcomes of gemcitabine-treated patients with inoperable biliary tract cancers. METHODS:We conducted a retrospective study of consecutively treated 22 inoperable biliary tract cancer patients with gemcitabine (500-1,000 mg/m(2) on days 1, 8, 15 every 4 weeks) as f...

journal_title：Oncology

authors： Kiba T,Nishimura T,Matsumoto S,Hatano E,Mori A,Yasumi S,Doi R,Ikai I,Kitano T,Nishimura T,Yoshikawa K,Ishiguro H,Yanagihara K,Doi E,Teramukai S,Fukushima M

更新日期：2006-01-01 00:00:00

abstract：:Nucleophosmin/B23 is a nucleolar phosphoprotein which redistributes from nucleoli to nucleoplasm (B23-translocation) when cells are exposed to certain anticancer drugs, particularly intercalators. The B23-translocation assay has been demonstrated in cell culture to correlate with drug effects and to detect drug-resist...

journal_title：Oncology

authors： Finch RA,Chan PK

更新日期：1992-01-01 00:00:00

abstract：:Patients with polycythemia vera (PV) experience shortened survival, increased risk of thromboembolic and hemorrhagic events, and burdensome symptoms. For all patients with PV, treatment with aspirin and hematocrit control with phlebotomy are recommended. In addition, patients with high-risk status or poor hematocrit c...

journal_title：Oncology

authors： Gerds AT,Dao KH

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:To examine the efficacy and prognostic benefits of radiotherapy (RT) in patients who have unresectable advanced hepatocellular carcinoma (HCC) with invasion to intrahepatic large vessels (IHLVs). METHODS:Sixty-eight patients who had advanced HCC with invasion to IHLVs were studied. Thirty-two consecutive pa...

journal_title：Oncology

authors： Nakazawa T,Adachi S,Kitano M,Isobe Y,Kokubu S,Hidaka H,Ono K,Okuwaki Y,Watanabe M,Shibuya A,Saigenji K

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The clinical features of hepatocellular carcinoma (HCC) differ in patients with and without cirrhosis. OBJECTIVE:We aimed to investigate the long-term outcomes of noncirrhotic HCC patients after curative resection. METHODS:We retrospectively examined 649 consecutive patients with HCC who underwent curative...

journal_title：Oncology

authors： Lee HW,Choi GH,Kim DY,Park YN,Kim KS,Choi JS,Ahn SH,Han KH

更新日期：2017-01-01 00:00:00

abstract：:The levels of 3',5'-cyclic adenosine monophosphate (cAMP) were measured in a high malignant and a low malignant clone of murine fibrosarcoma cells isolated from a common parent in a normal mouse fibroblasts at various stages of growth. There was an inverse correlation between the degree of malignant potential and the ...

journal_title：Oncology

authors： Elgebaly S,Kunkel S,Lovett EJ,Varani J

更新日期：1982-01-01 00:00:00

abstract：:A total of 103 patients with lung cancer was treated with CCNU 130 mg/m2 orally every 6 weeks; 65 patients survived at least 6 weeks. Partial responses occurred in 7 patients. Leukopenia, thrombocytopenia, and nausea were frequent toxic effects. CCNU has slight efficacy in advanced lung cancer. No increase in survival...

journal_title：Oncology

authors： Stolinsky DC,Bull FE,Pajak TF,Bateman JR

更新日期：1975-01-01 00:00:00

abstract：:A number of therapeutic agents including L-asparaginase, Actinomycin-D, CCNU, Hydroxyurea, 5-FU, Cis-platinum, Cyclophosphamide, orchiectomy, Adriamycin and DES alone and in various combinations has been applied against the Dunning R-3327 rat prostatic adenocarcinoma subline G. We have found a parallel between the res...

journal_title：Oncology

authors： Block NL,Camuzzi F,Denefrio J,Troner M,Claflin A,Stover B,Politano VA

更新日期：1977-01-01 00:00:00