Antiemetic efficacy of moderately high-dose metoclopramide in patients receiving varying doses of cisplatin. Controlled comparison with a combination of methylprednisolone and metoclopramide.

abstract：:An increase in serum iron levels and a decrease in serum unsaturated iron binding capacity (uIBC) were noted following the administration of cisplatinum to 9 children with malignancies. The mean serum iron concentration increased from a pretreatment level of 75.7 +/- 30.5 micrograms/ml to a posttreatment level of 162....

journal_title：Oncology

authors： Kletter G,Parks BR Jr,Bhatnagar A,Iyer RV

更新日期：1988-01-01 00:00:00

abstract：:We have provided an in-depth, longitudinal, clinical/genetic/pathologic investigation of a family consonant with the sarcoma, breast cancer and brain tumors, lung and laryngeal cancer, leukemia, lymphoma, and adrenalcortical carcinoma syndrome. The pattern of cancer expression involves all three germinal layers with t...

journal_title：Oncology

authors： Lynch HT,Radford B,Lynch JF

更新日期：1990-01-01 00:00:00

abstract：:Methyl-CCNU (NSC-95441) was administered to patients with malignant melanoma in a split dose schedule. Nausea and vomiting were eliminated as clinical problems during therapy. Response rate to the drug seemed somewhat lower than the average of three previously reported disease-oriented phase II trials, though the diff...

journal_title：Oncology

authors： Wittes RE,Hong WK,Gatchell L,Krakoff IH,Golbey RB

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to investigate whether the Ile646Val (2073A>G) polymorphism in the kinase-binding domain of A-kinase anchoring protein 10 (AKAP10) is related to the risk of colorectal cancer (CRC), clinicopathological variables and the environmental factors for the development of CRC. METHODS:Ap...

journal_title：Oncology

authors： Wang MJ,Zhou ZG,Wang L,Yu YY,Zhang P,Zhang Y,Cui CF,Yang L,Li Y,Zhou B,Sun XF

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:This study aimed to investigate clinicopathological responses and oncological outcome in patients receiving short- or long-course chemoradiotherapy (CRT) and to assess the predictive factor for recurrence in each treatment. METHODS:A total of 118 rectal cancer patients receiving preoperative CRT were enrolle...

journal_title：Oncology

authors： Yamamoto A,Toiyama Y,Okugawa Y,Saigusa S,Ide S,Fujikawa H,Hiro J,Yasuda H,Yoshiyama S,Ohi M,Araki T,Kusunoki M

更新日期：2019-01-01 00:00:00

abstract：:203 tumor specimens from 175 patients were studied. Amplification of ERBB-2 was detected in 14 out of 63 (22%) cases of breast carcinoma, in 1 out of 23 patients with ovarian cancers, in 1 out of 19 cases of colon carcinoma and in 1 out of 27 patients with thyroid cancer. We failed to find more than one copy of ERBB-2...

journal_title：Oncology

authors： Knyazev PG,Imyanitov EN,Chernitca OI,Nikiforova IF,Hanson KP

更新日期：1992-01-01 00:00:00

abstract：:Human papillomaviruses (HPVs) have been linked to a variety of human diseases, most notably cancer of the cervix. In the majority of cases, HPV proteins E6 and E7 are continuously expressed and bind a variety of cellular proteins. The precise mechanism of HPV-induced carcinogenesis has not been fully elucidated; there...

journal_title：Oncology

authors： Yaginuma Y,Yoda K,Ogawa K

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of neoadjuvant treatment comprising weekly high-dose 5-fluorouracil (5-FU) as a 24-hour infusion, folinic acid (FA) and biweekly oxaliplatin (L-OHP), followed by metastatic resection in patients with primarily resectable liver metastases of colorectal cancer (CRC). PATIENTS ...

journal_title：Oncology

authors： Wein A,Riedel C,Brückl W,Merkel S,Ott R,Hanke B,Baum U,Fuchs F,Günther K,Reck T,Papadopoulos T,Hahn EG,Hohenberger W

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:Pediatric-type sarcomas such as Ewing's sarcoma (EWS)/primitive neuroectodermal tumor family and rhabdomyosarcoma are relatively uncommon in adult patients. Optimal treatment strategies for this population and prognosis in adult patients compared with pediatric patients remain controversial. METHODS:We retro...

journal_title：Oncology

authors： Ahn HK,Uhm JE,Lee J,Lim DH,Seo SW,Sung KS,Lee SJ,Lee DJ,Baek KK,Kim WS,Park JO

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Adenocarcinoma is the most frequent pathological type of stomach cancer. Hodgkin's lymphoma is a lymphoproliferative disease arising from lymphoid tissue which is characterized by Reed-Sternberg cells. Synchronous occurrence of these two malignancies has not been reported in the English literature so far. C...

journal_title：Oncology

authors： Comez G,Pehlivan Y,Kalender ME,Sevinc A,Sari I,Camci C

更新日期：2007-01-01 00:00:00

abstract：:Antineoplastic properties of different Schiff bases obtained by the interaction of 5-nitrofuran with substituted pyrimidines have been examined both in vitro and in vivo. In vitro studies on L 5178Y/asparaginase sensitive, HL 60 and P 388 cell lines and in vivo studies on the P 388 cell line indicate that all the comp...

journal_title：Oncology

authors： Sur B,Chatterjee SP,Sur P,Maity T,Roychoudhury S

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:The objective of this phase III trial was to compare chemotherapy combined with bevacizumab versus chemotherapy alone in the treatment of patients with advanced colorectal cancer. METHODS:From September 2004 till September 2008, 222 treatment-naive patients were enrolled and divided into 2 arms: 114 arm A pa...

journal_title：Oncology

authors： Stathopoulos GP,Batziou C,Trafalis D,Koutantos J,Batzios S,Stathopoulos J,Legakis J,Armakolas A

更新日期：2010-01-01 00:00:00

abstract：:This paper reviews the effectiveness of local interleukin-2 (IL-2) therapy and its effector induction mechanisms in vivo. Local therapy with IL-2 and/or lymphokine-activated killer (LAK) cells is associated with far fewer side effects than systemic treatment. Local infusions of IL-2 into malignant pleural effusions an...

journal_title：Oncology

authors： Sone S,Ogura T

更新日期：1994-03-01 00:00:00

abstract：:Sixteen patients with histologically confirmed inoperable hepatocellular carcinoma were treated with vindesine 3 mg/m2 i.v. weekly. Anemia, leukopenia and neuritis were documented but no severe or life-threatening toxicity was seen. There were no objective responses among the 14 evaluable patients. Eight had a no chan...

journal_title：Oncology

authors： Falkson G,Burger W

更新日期：1995-01-01 00:00:00

abstract：:To improve the ability of an in vitro drug sensitivity test to predict in vivo effects, we applied a drug concentration that was pharmacokinetically equivalent to plasma levels and collagen gel droplet-embedded culture with a high cloning efficiency. We reported that the cell-killing effect of cell cycle phase-nonspec...

journal_title：Oncology

authors： Inaba M,Tashiro T,Sato S,Ohnishi Y,Tanisaka K,Kobayashi H,Koezuka M

更新日期：1996-05-01 00:00:00

abstract：:The serum detection of S100B, a new melanoma marker, has shown clinical significance in early studies. The aim of our study of 1, 339 serum samples from 412 different melanoma patients and 107 control patients was to prove the prognostic value of serum S100B levels in melanoma patients at different stages of disease a...

journal_title：Oncology

authors： Hauschild A,Engel G,Brenner W,Gläser R,Mönig H,Henze E,Christophers E

更新日期：1999-01-01 00:00:00

abstract：:Cancer pain management had received relatively little attention until the late 1990s, when approximately 100,000 new cancer cases and 60,000 cancer deaths occurred each year in Korea. In 2001, a Cancer Pain Management Guideline was prepared for the first time by the Korean Society of Hospice and Palliative Care. This ...

journal_title：Oncology

authors： Lee JY,Ahn JS

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Immuno-oncological (IO) therapies such as PD-1 and PD-L1 antibodies have been introduced in the treatment of advanced non-small cell lung cancer (NSCLC) since 2015 based on randomized trials showing unprecedented advantages in overall survival (OS) with hazard ratios (HRs) between 0.5 and 0.7. The impact of ...

journal_title：Oncology

authors： Faehling M,Kopp M,Schwenk B,Fallscheer S,Kramberg S,Eckert R

更新日期：2019-01-01 00:00:00

abstract：:We report a rare case of a patient with an intrasplenic malignant fibrous histiocytoma (MFH) and chronic myelogenous leukemia. The neoplasms were synchronous in their onset and evolution. The peculiarity of the primary site of the MFH, the genetic implications of multiple primary tumors in a single patient, and the co...

journal_title：Oncology

authors： Bonilla F,Provencio M,Fernandez E,España P

更新日期：1994-09-01 00:00:00

abstract：:Eleven postmenopausal patients with advanced breast cancer were assessed for their response and endocrine changes to low-dose aminoglutethimide (250 mg twice a day) therapy without steroid administration. In 7 cases an objective response was registered; 1 patient had a stabilization of the disease lasting for 9 months...

journal_title：Oncology

authors： Kahán Z,Tóth I,Vecsernyés M

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:The present study evaluated the clinical relevance of an integrative preoperative assessment of inflammation-, nutrition-, and muscle-based markers for patients with muscle-invasive bladder cancer (MIBC) undergoing curative radical cystectomy (RC). METHODS:The analysis enrolled 117 patients and the variables...

journal_title：Oncology

authors： Miyake M,Morizawa Y,Hori S,Marugami N,Iida K,Ohnishi K,Gotoh D,Tatsumi Y,Nakai Y,Inoue T,Anai S,Torimoto K,Aoki K,Tanaka N,Shimada K,Konishi N,Fujimoto K

更新日期：2017-01-01 00:00:00

abstract：:A transplantable transitional cell murine bladder tumor induced by N-[4-(5-nitro-2-furyl)-thiazolyl] formamide (FANFT) was characterized by tumor growth, survival time and response to chemotherapy drugs, cis-dichloro-trans-dihydroxy-bis-iso-propylamine platinum IV (CHIP), cis- diaminedichloro platinum II (DDP), cyclop...

journal_title：Oncology

authors： Murphy GP,Pontes JE,Williams PD

更新日期：1984-01-01 00:00:00

abstract：:Malignant gastrointestinal neuroectodermal tumor (GNET) is an aggressive rare tumor, primarily occurring in young adults with frequent local-regional metastases and recurrence after local control. The tumor is characterized by the presence of EWSR1-ATF1 or EWSR1-CREB1 and immunohistochemical positivity for S-100 prote...

journal_title：Oncology

authors： Subbiah V,Holmes O,Gowen K,Spritz D,Amini B,Wang WL,Schrock AB,Meric-Bernstam F,Zinner R,Piha-Paul S,Zarzour M,Elvin JA,Erlich RL,Stockman DL,Vergilio JA,Suh JH,Stephens PJ,Miller V,Ross JS,Ali SM

更新日期：2016-01-01 00:00:00

abstract：AIMS:We investigated the relationship between serum leptin concentrations and polymorphism of the leptin receptor gene and breast cancer. METHODS:Serum leptin concentrations were measured by enzyme-linked immunosorbent assay in 47 women with invasive breast cancer compared with 41 age-matched controls without cancer. ...

journal_title：Oncology

authors： Liu CL,Chang YC,Cheng SP,Chern SR,Yang TL,Lee JJ,Guo IC,Chen CP

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Previous data showed that distant metastatic breast cancer (MBC) might be curable in up to 3% of the cases in selected patients, mostly young, with good performance status and with low-volume metastatic disease, mainly by an aggressive multidisciplinary approach including aggressive combination chemotherapy ...

journal_title：Oncology

authors： Güth U,Elfgen C,Montagna G,Schmid SM

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:Insulin-like growth factor I (IGF-I) and other components of the IGF system have been implicated in the etiology of several human malignancies. We have undertaken a case-control study among Greek women to explore the relation of major components of the IGF system (IGF-I, IGF-II and IGF-binding protein 3, IGF...

journal_title：Oncology

authors： Petridou E,Koukoulomatis P,Alexe DM,Voulgaris Z,Spanos E,Trichopoulos D

更新日期：2003-01-01 00:00:00

abstract：:Culture-induced cytotoxic (CIC) activity developed in 7-day culture in the presence of fetal calf serum of pleural effusion lymphocytes from patients with lung cancer which initially showed markedly low or no natural killing (NK) activity against K562 cells. The development of CIC activity was proliferation-dependent....

journal_title：Oncology

authors： Uchida A,Micksche M

更新日期：1982-01-01 00:00:00

abstract：AIM:The aim of this study was to assess the molecular subtype profiles of male breast cancer (MBC) and subsequent clinical outcome using a validated 6-marker immunohistochemical panel. METHODS:A total of 43 cases of MBC were examined retrospectively using a semiquantitative immunohistochemical analysis of estrogen rec...

journal_title：Oncology

authors： Sánchez-Muñoz A,Román-Jobacho A,Pérez-Villa L,Sánchez-Rovira P,Miramón J,Pérez D,Sáez MI,de Luque V,Medina L,Ramírez-Tortosa CL,Vicioso L,Medina JA,Ribelles N,Alba E

更新日期：2012-01-01 00:00:00

abstract：:This is a phase II study to evaluate the efficacy and toxicity of short-course carboplatin in advanced-stage nasopharyngeal carcinoma (NPC). Thirty-three previously untreated stage III-IV NPC patients were studied. Carboplatin was given as a rapid intravenous injection every 3 weeks. The dose of carboplatin was calcul...

journal_title：Oncology

authors： Chi KH,Chang YC,Chan WK,Liu JM,Law CK,Lo SS,Shu CH,Yen SH,Whang-Peng J,Chen KY

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVES:Anaplastic oligodendrogliomas (AO) are uncommon primary brain tumors whose natural history, prognosis, and optimal management are not yet fully understood. However, they are associated with a better prognosis and response to multimodality therapy based on specific molecular changes. In this multicenter retro...

journal_title：Oncology

authors： Puduvalli VK,Hashmi M,McAllister LD,Levin VA,Hess KR,Prados M,Jaeckle KA,Yung WK,Buys SS,Bruner JM,Townsend JJ,Davis R,Sawaya R,Kyritsis AP

更新日期：2003-01-01 00:00:00