A phase II trial of vindesine in hepatocellular cancer.

Abstract:

:Sixteen patients with histologically confirmed inoperable hepatocellular carcinoma were treated with vindesine 3 mg/m2 i.v. weekly. Anemia, leukopenia and neuritis were documented but no severe or life-threatening toxicity was seen. There were no objective responses among the 14 evaluable patients. Eight had a no change status (median duration of 16 weeks, range 6-33), while the remaining 6 had progressive disease as their best evaluation. The median survival time was 20 weeks. Vindesine does not have a therapeutic effect in patients with advanced hepatocellular carcinoma.

journal_name

Oncology

journal_title

Oncology

authors

Falkson G,Burger W

doi

10.1159/000227434

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

86-7

issue

1

eissn

0030-2414

issn

1423-0232

journal_volume

52

pub_type

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