Abstract:
:Sixteen patients with histologically confirmed inoperable hepatocellular carcinoma were treated with vindesine 3 mg/m2 i.v. weekly. Anemia, leukopenia and neuritis were documented but no severe or life-threatening toxicity was seen. There were no objective responses among the 14 evaluable patients. Eight had a no change status (median duration of 16 weeks, range 6-33), while the remaining 6 had progressive disease as their best evaluation. The median survival time was 20 weeks. Vindesine does not have a therapeutic effect in patients with advanced hepatocellular carcinoma.
journal_name
Oncologyjournal_title
Oncologyauthors
Falkson G,Burger Wdoi
10.1159/000227434subject
Has Abstractpub_date
1995-01-01 00:00:00pages
86-7issue
1eissn
0030-2414issn
1423-0232journal_volume
52pub_type
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