Malignant fibrous histiocytoma of the spleen and chronic myelogenous leukemia. A case report.

abstract：:Acute myeloid leukemia (AML) originates from self-renewing leukemic stem cells (LSCs), an ultimate therapeutic target in AML. Eradication of LSCs should be a critical and efficient therapeutic approach for the cure of AML. T-cell immunoglobulin mucin-3 (TIM-3) is expressed in most types of AML LSCs, but not in normal ...

journal_title：Oncology

authors： Kikushige Y,Miyamoto T

更新日期：2015-01-01 00:00:00

abstract：:In 35 children with acute lymphatic or undifferentiated leukemia, immunological properties of normal lymphocytes and lymphoblasts were investigated. In most cases the number of circulating normal lymphocytes with surface or B markers and delayed type hypersensitivity was depressed. On the other hand, the response to m...

journal_title：Oncology

authors： Winterleitner H,Rella W,Eibl M,Krepler P

更新日期：1978-01-01 00:00:00

abstract：OBJECTIVE:Expression of vascular endothelial growth factor (VEGF)-D by tumors is associated with metastasis to lymph nodes in mice. However, there are few reports concerning the clinical significance of VEGF-D protein in human carcinoma. METHODS:After confirming production of VEGF-D by eight colorectal carcinoma cell ...

journal_title：Oncology

authors： Funaki H,Nishimura G,Harada S,Ninomiya I,Terada I,Fushida S,Tani T,Fujimura T,Kayahara M,Shimizu K,Ohta T,Miwa K

更新日期：2003-01-01 00:00:00

abstract：:Information technology (IT) can enhance or change many scenarios in cancer research for the better. In this paper, we introduce several examples, starting with clinical data reuse and collaboration including data sharing in research networks. Key challenges are semantic interoperability and data access (including data...

journal_title：Oncology

authors： Ahlbrandt J,Lablans M,Glocker K,Stahl-Toyota S,Maier-Hein K,Maier-Hein L,Ückert F

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:A novel delivery system for transdermal matrix patches of fentanyl has been developed. The new fentanyl tape consists of a backing layer, a drug-containing layer and a release liner that is originally made of rubber adhesive. This open-label prospective study investigated the pharmacokinetics and safety of t...

journal_title：Oncology

authors： Saito T,Fujii M,Saito S,Shimada K,Fujiwara K,Kobayashi K

更新日期：2014-01-01 00:00:00

abstract：:Irinotecan and raltitrexed are active against advanced colorectal cancer, act through different mechanisms, and have non-overlapping toxicity profiles. In vitro studies have shown a schedule-dependent synergism between both drugs. The aim of this multicenter study was to determine the maximum tolerated dose (MTD) of t...

journal_title：Oncology

authors： Aparicio J,de las Peñas R,Vicent JM,Garcerá S,Llorca C,Maestu I,Yuste AL,Farrés J

更新日期：2002-01-01 00:00:00

abstract：:203 tumor specimens from 175 patients were studied. Amplification of ERBB-2 was detected in 14 out of 63 (22%) cases of breast carcinoma, in 1 out of 23 patients with ovarian cancers, in 1 out of 19 cases of colon carcinoma and in 1 out of 27 patients with thyroid cancer. We failed to find more than one copy of ERBB-2...

journal_title：Oncology

authors： Knyazev PG,Imyanitov EN,Chernitca OI,Nikiforova IF,Hanson KP

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVES:A phase II study was performed to investigate the safety and efficacy of concurrent chemoradiotherapy (CCRT) combined with an orally active fluoropyrimidine, S-1, plus cisplatin for locally advanced esophageal cancer (LAEC). METHODS:CCRT comprised 2 courses, a 30-Gy radiotherapy over 3 weeks plus daily oral...

journal_title：Oncology

authors： Iwase H,Shimada M,Tsuzuki T,Hirashima N,Okeya M,Hibino Y,Ryuge N,Yokoi M,Kida Y,Kuno T,Tanaka Y,Kato B,Esaki M,Urata N,Kato E

更新日期：2013-01-01 00:00:00

abstract：:The disease provoked by injections of water and other harmless liquids or wounds without tissue loss, is characterized by the regression of certain organs, opening in the epidermis, pigmentary anomalies and malignant tumors. The very few worms which recover spontaneously, regenerate the eliminated parts or develop sup...

journal_title：Oncology

authors： Chandebois R

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND:Immuno-oncological (IO) therapies such as PD-1 and PD-L1 antibodies have been introduced in the treatment of advanced non-small cell lung cancer (NSCLC) since 2015 based on randomized trials showing unprecedented advantages in overall survival (OS) with hazard ratios (HRs) between 0.5 and 0.7. The impact of ...

journal_title：Oncology

authors： Faehling M,Kopp M,Schwenk B,Fallscheer S,Kramberg S,Eckert R

更新日期：2019-01-01 00:00:00

abstract：:The association of MMP-2 (matrix metalloproteinase 2, 72-kD collagenase IV) with invasive and metastatic capacity of tumor cells has implicated a potential role in the prognosis for cancer patients. However, no larger study has been done to prove this hypothesis. The present study was therefore designed to investigate...

journal_title：Oncology

authors： Allgayer H,Babic R,Beyer BC,Grützner KU,Tarabichi A,Schildberg FW,Heiss MM

更新日期：1998-03-01 00:00:00

abstract：:A loss of heterozygosity (LOH) at the DCC gene locus was detected in colorectal tumors, and this LOH might be related to metastasis. The aim of this study was to determine DCC protein expression in colorectal cancer and to evaluate its prognostic value. Allelic loss of the DCC locus was observed in 16 of the 23 patien...

journal_title：Oncology

authors： Saito M,Yamaguchi A,Goi T,Tsuchiyama T,Nakagawara G,Urano T,Shiku H,Furukawa K

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:The objective of this phase III trial was to compare chemotherapy combined with bevacizumab versus chemotherapy alone in the treatment of patients with advanced colorectal cancer. METHODS:From September 2004 till September 2008, 222 treatment-naive patients were enrolled and divided into 2 arms: 114 arm A pa...

journal_title：Oncology

authors： Stathopoulos GP,Batziou C,Trafalis D,Koutantos J,Batzios S,Stathopoulos J,Legakis J,Armakolas A

更新日期：2010-01-01 00:00:00

abstract：UNLABELLED:The outlook for patients with testicular germ cell cancer was dramatically improved by the introduction of cisplatin. Well-known side effects of cisplatin (nausea, vomiting, nephrotoxicity, myelosuppression) can be managed with preventive methods. The long life expectancy after this therapy draws attention t...

journal_title：Oncology

authors： Biró K,Baki M,Büki B,Noszek L,Jókúti L

更新日期：1997-09-01 00:00:00

abstract：PURPOSE:Patient nonadherence to oral antineoplastic therapy is a well-recognized barrier to effective treatment. In order to identify patients who may need additional support to become adherent, it is important to have a useful tool that takes into account all the parameters of adherence to prescription. The aim of thi...

journal_title：Oncology

authors： Thivat E,Van Praagh I,Belliere A,Mouret-Reynier MA,Kwiatkowski F,Durando X,Mahammedi H,Dillies AF,Chollet P,Chevrier R

更新日期：2013-01-01 00:00:00

abstract：:The toxicity of 1-[2-(diethylamino)ethyl]reserpine (DL-152) has been measured for 4 transplantable mouse tumors. DL-152 was found to be toxic to cells of all the tumor models tested (KHT fibrosarcoma, RIF-1 fibrosarcoma, EMT-6 adenocarcinoma and Lewis lung carcinoma) when the drug was given by intraperitoneal injectio...

journal_title：Oncology

authors： Lehnert S

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Variations in the incidence of cancer can be influenced by diet and specific lifestyles. In the last years, diet has been evaluated as an important factor in the development of ovarian cancer, even though the results have not been consistent. Dietary factors related to the risk of ovarian cancer in Mexican w...

journal_title：Oncology

authors： Salazar-Martinez E,Lazcano-Ponce EC,Gonzalez Lira-Lira G,Escudero-De los Rios P,Hernandez-Avila M

更新日期：2002-01-01 00:00:00

abstract：:Ifosfamide is relatively well tolerated but it can be associated occasionally with life-threatening complications such as arrhythmias and heart failure, severe encephalopathy and hemorrhagic cystitis. Mesna administration can control the urothelial toxicity of ifosfamide, but it is without effect on the other complica...

journal_title：Oncology

authors： Klastersky J

更新日期：2003-01-01 00:00:00

abstract：AIM:The aim of this study was to assess the molecular subtype profiles of male breast cancer (MBC) and subsequent clinical outcome using a validated 6-marker immunohistochemical panel. METHODS:A total of 43 cases of MBC were examined retrospectively using a semiquantitative immunohistochemical analysis of estrogen rec...

journal_title：Oncology

authors： Sánchez-Muñoz A,Román-Jobacho A,Pérez-Villa L,Sánchez-Rovira P,Miramón J,Pérez D,Sáez MI,de Luque V,Medina L,Ramírez-Tortosa CL,Vicioso L,Medina JA,Ribelles N,Alba E

更新日期：2012-01-01 00:00:00

abstract：:In 12 patients with gastric cancer and in 14 with large bowel neoplasia, classified according to the TNM system, some major blood indices of hemostasis, platelet activation and fibrinolysis were assessed before and for 1 month after surgery, to show whether possible variations of such indices may provide useful clues ...

journal_title：Oncology

authors： Abbasciano V,Guerra S,Reali MG,Guglielmini C

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:To investigate the potential benefit of intermittent chemotherapy, and to identify the eligibility criteria offering intermittent chemotherapy to patients with advanced urothelial cancer. MATERIALS AND METHODS:Twenty patients who responded or had stable disease after receiving 3 cycles of induction chemother...

journal_title：Oncology

authors： Onishi T,Sasaki T,Hoshina A

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:To date, the clinical characteristics of coronavirus disease 19 (COVID-19)-infected urologic cancer patients are unknown. METHODS:We have analyzed all patients with prostate cancer undergoing hormonal or chemotherapy treatment and receiving telephone and in person pre-triage between March 1 and 27, 2020, at...

journal_title：Oncology

authors： Di Lorenzo G,Buonerba L,Ingenito C,Crocetto F,Buonerba C,Libroia A,Sciarra A,Ragone G,Sanseverino R,Iaccarino S,Napodano G,Imbimbo C,Leo E,Kozlakidis Z,De Placido S

更新日期：2020-01-01 00:00:00

abstract：AIMS:We investigated the relationship between serum leptin concentrations and polymorphism of the leptin receptor gene and breast cancer. METHODS:Serum leptin concentrations were measured by enzyme-linked immunosorbent assay in 47 women with invasive breast cancer compared with 41 age-matched controls without cancer. ...

journal_title：Oncology

authors： Liu CL,Chang YC,Cheng SP,Chern SR,Yang TL,Lee JJ,Guo IC,Chen CP

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:Cancer-related fatigue is a common complaint during cancer treatment and is often associated with cognitive impairment. This study examined cognitive deficits that were associated with fatigue symptoms during external-beam radiation therapy (EBRT) in men with localized prostate cancer. METHODS:A total of 36 pa...

journal_title：Oncology

authors： Feng LR,Espina A,Saligan LN

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Patients with localized esophageal and esophagogastric junction cancer (EAC) receive chemoradiation and then surgery (trimodality, TMT) or definitive chemoradiation (bimodality, BMT). Distant metastases (DMs) are common but the details of their distribution and timing in a large cohort have not been describe...

journal_title：Oncology

authors： Shiozaki H,Sudo K,Xiao L,Wadhwa R,Elimova E,Hofstetter WL,Skinner HD,Lee JH,Weston B,Bhutani MS,Blum MA,Maru DM,Ajani JA

更新日期：2014-01-01 00:00:00

abstract：:During the period 1965-1980, 84 patients with Wilms' tumor, neuroblastoma and Ewing's sarcoma were treated at the University of Rochester Medical Center. All patients were evaluated for the presence of congenital abnormalities. Ten of 34 (29%) patients with Wilms' tumor, 3 of 32 (9%) patients with neuroblastoma, and 0...

journal_title：Oncology

authors： Nakissa N,Constine LS,Rubin P,Strohl R

更新日期：1985-01-01 00:00:00

abstract：:This is a case report of hyperpyrexia, shock and death following initial injection of low-dose bleomycin (7.5 units) for a poorly differentiated metastatic carcinoma. Premedication with high-dose dexamethasone and acetaminophen did not abort the reaction. A review of the literature uncovered one nearly fatal reaction ...

journal_title：Oncology

authors： Levy RL,Chiarillo S

更新日期：1980-01-01 00:00:00

abstract：:The encouraging results that have been reported for cisplatin combination chemotherapy in a minority of patients with cancer of unknown primary (CUP) together with the previously shown equal activity of carboplatin in this setting, prompted us to investigate the effectiveness of a carboplatin-containing regimen in a p...

journal_title：Oncology

authors： Briasoulis E,Tsavaris N,Fountzilas G,Athanasiadis A,Kosmidis P,Bafaloukos D,Skarlos D,Samantas E,Pavlidis N

更新日期：1998-09-01 00:00:00

abstract：:CA 19-9 and tissue polypeptide antigen (TPA) were determined in the sera of 28 control subjects, 29 patients with pancreatic cancer, 26 with chronic pancreatitis and 62 with benign and malignant extra pancreatic diseases in order to compare their usefulness in diagnosing pancreatic cancer, to verify whether the combin...

journal_title：Oncology

authors： Basso D,Fabris C,Del Favero G,Panucci A,Plebani M,Angonese C,Leandro G,Dodi G,Burlina A,Naccarato R

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:We evaluated the efficacy and safety of bolus 5-fluorouracil (5-FU) and leucovorin combined with weekly paclitaxel (FLTAX) in advanced gastric cancer (GC) patients. METHODS:Patients with untreated stage IV GC received paclitaxel 80 mg/m(2) as a 1-hour infusion, followed by 5-FU 600 mg/m(2) as a bolus infusio...

journal_title：Oncology

authors： Matsubara J,Shimada Y,Kato K,Nagai Y,Iwasa S,Nakajima TE,Hamaguchi T,Yamada Y,Takagi S,Kobayashi K,Yoshioka A,Nakayama N,Tsuji A

更新日期：2011-01-01 00:00:00