Adherence with oral oncologic treatment in cancer patients: interest of an adherence score of all dosing errors.

abstract：:In patients affected with different tumours, disorders concerning clotting are frequently observed. The biological processes leading to coagulation are probably involved in the mechanisms of metastasis. We studied plasma levels of thrombin-antithrombin III complexes (TAT) in 90 patients affected with lung tumours subg...

journal_title：Oncology

authors： Tricerri A,Vangeli M,Errani AR,Guidi L,Canetta M,Vaccarino M,De Santis C,Ipsevich F,Salvati F,Bartoloni C

更新日期：1996-11-01 00:00:00

abstract：OBJECTIVES:Our aim was to assess FDG-PET/CT as a surrogate biomarker of the pathological complete response in locally advanced rectal cancer treated with neoadjuvant chemoradiation. METHODS:T3-4 and/or N+ rectal cancer patients were treated prospectively with capecitabine-based chemoradiation and total mesorectal exci...

journal_title：Oncology

authors： Bampo C,Alessi A,Fantini S,Bertarelli G,de Braud F,Bombardieri E,Valvo F,Crippa F,Di Bartolomeo M,Mariani L,Milione M,Biondani P,Avuzzi B,Chiruzzi C,Pietrantonio F

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:Breast cancer (BC) is the most frequent female carcinoma and the major cause of death in women aged 35--50 years. The total number of patients surviving BC and especially the morbidity rate of patients below the age of 55 years has increased significantly in the last several years. As a consequence, the number ...

journal_title：Oncology

authors： Beckmann MW,Jap D,Djahansouzi S,Nestle-Krämling C,Kuschel B,Dall P,Brumm C,Bender HG

更新日期：2001-01-01 00:00:00

abstract：:Repeated ultraviolet light (UV) irradiation on the skin of rats caused ulceration, scarring and epithelial tumors; 38% of the animals had ear tumors and 5% skin tumors. Guinea pigs presented minimal evidence of neoplastic transformation; only two tumors were seen while hamsters displayed localized epidermal hyperplasi...

journal_title：Oncology

authors： Stenbäck F

更新日期：1975-01-01 00:00:00

abstract：OBJECTIVE:The herpes simplex virus thymidine kinase (HSVtk)/ganciclovir suicide gene therapy system has been considered as one of the most promising therapeutic strategies for malignant gliomas. We have been using HSVtk gene-transduced neural stem cells (NSCtk) that possess an ability to migrate toward a tumor mass for...

journal_title：Oncology

authors： Li S,Tokuyama T,Yamamoto J,Koide M,Yokota N,Namba H

更新日期：2005-01-01 00:00:00

abstract：:Studies were made of the therapeutic response of six human colorectal tumor lines serially transplanted in immunosuppressed mice. The tumors with adenomatous structure showed greater sensitivity against different cytotoxic agents than the gelatinous ones. Among the drugs, 5-FU, BCNU and MeCCNU proved to be the most ef...

journal_title：Oncology

authors： Kopper L,Lapis K,Hegedüs C

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to investigate whether the Ile646Val (2073A>G) polymorphism in the kinase-binding domain of A-kinase anchoring protein 10 (AKAP10) is related to the risk of colorectal cancer (CRC), clinicopathological variables and the environmental factors for the development of CRC. METHODS:Ap...

journal_title：Oncology

authors： Wang MJ,Zhou ZG,Wang L,Yu YY,Zhang P,Zhang Y,Cui CF,Yang L,Li Y,Zhou B,Sun XF

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:MicroRNA (miR)-503 is downregulated in several cancers and plays a tumor-suppressive role in carcinogenesis. However, the miR-503 expression pattern, its clinical significance and its molecular mechanism in colorectal cancer (CRC) have not been investigated. METHODS:We analyzed miR-503 expression in normal ...

journal_title：Oncology

authors： Noguchi T,Toiyama Y,Kitajima T,Imaoka H,Hiro J,Saigusa S,Tanaka K,Inoue Y,Mohri Y,Toden S,Kusunoki M

更新日期：2016-01-01 00:00:00

abstract：:We developed a new transcutaneous method for breast cancer detection with dogs: 2 dogs were trained to sniff skin secretion samples on compresses that had been worn overnight by women on their breast, and to recognize a breast cancer sample among 4 samples. During the test, the dogs recognized 90.3% of skin secretion ...

journal_title：Oncology

authors： Thuleau A,Gilbert C,Bauër P,Alran S,Fourchotte V,Guillot E,Vincent-Salomon A,Kerihuel JC,Dugay J,Semetey V,Kriegel I,Fromantin I

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:We retrospectively investigated the treatment outcomes of second-line treatment with pazopanib or gemcitabine/docetaxel in patients with advanced soft tissue sarcoma (STS). METHODS:Ninety-one patients who were treated with pazopanib or gemcitabine/docetaxel for advanced STS between 1995 and 2015 were analyz...

journal_title：Oncology

authors： Kim JH,Park HS,Heo SJ,Kim SK,Han JW,Shin KH,Kim SH,Hur H,Kim KS,Choi YD,Kim S,Lee YH,Suh JS,Ahn JB,Chung HC,Noh SH,Rha SY,Kim HS

更新日期：2019-01-01 00:00:00

abstract：:To assess the prognostic value of pretreatment serum neuron-specific enolase (NSE) in nonsmall cell lung cancer (NSCLC), levels were measured in 84 NSCLC patients, 40 healthy controls, and 20 patients with benign pulmonary diseases. NSE concentration was higher in NSCLC (11.7 +/- 10.8 ng/ml) (mean +/- SD; median = 9.7...

journal_title：Oncology

authors： Diez M,Torres A,Ortega L,Maestro M,Hernando F,Gomez A,Picardo A,Granell J,Balibrea JL

更新日期：1993-03-01 00:00:00

abstract：:We examined the effects of cycloheximide on the amount of chromatin-bound and -unbound PCNA subpopulations in HeLa cells. The chromatin-bound PCNA content decreased rapidly in the presence of cycloheximide, whereas the reduction of the total amount of PCNA was minimal even 24 h after the treatment with cycloheximide. ...

journal_title：Oncology

authors： Sasaki K,Kurose A,Uesugi N,Kato A

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVES:A germline BIM deletion polymorphism has been proposed to predict a poor treatment efficacy of certain kinase inhibitors. The current study aimed to explore whether the BIM deletion polymorphism predicts the treatment efficacy of sorafenib for advanced hepatocellular carcinoma (HCC). METHODS:All patients wh...

journal_title：Oncology

authors： Shao YY,Chang YL,Huang CY,Hsu CH,Cheng AL

更新日期：2013-01-01 00:00:00

abstract：:In 323 of 1,620 patients with gastric cancer, the lesion was > or = 10 cm in maximum diameter. Studies were done with respect to clinicopathologic features and the prognosis. Patients with tumors > or = 10 cm were younger and women patients were more numerous compared to those with tumors < 10 cm. Tumors were more adv...

journal_title：Oncology

authors： Maehara Y,Oiwa H,Oda S,Sakaguchi Y,Endo K,Ohno S,Sugimachi K

更新日期：1995-01-01 00:00:00

abstract：:The authors have reviewed the medical records of 421 sessions of hyperthermia treatments in 73 patients treated between 1987 and 1992 at the University Heights Cancer Center and the Indiana University Medical Center in Indianapolis, Ind. Temperatures attained during the course of therapy on each patient have been aver...

journal_title：Oncology

authors： Shidnia H,Hornback N,Ford G,Shen RN

更新日期：1993-09-01 00:00:00

abstract：:2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), the most abundant food-derived mutagenic/carcinogenic heterocyclic amine (HCA), has attracted particular attention as a probable human colon carcinogen. Some studies have shown that PhIP administered in the post-initiation phase is able to enhance rat colon carci...

journal_title：Oncology

authors： Doi K,Hagihara A,Wei M,Yunoki T,Fukushima S,Wanibuchi H

更新日期：2007-01-01 00:00:00

abstract：:The disease provoked by injections of water and other harmless liquids or wounds without tissue loss, is characterized by the regression of certain organs, opening in the epidermis, pigmentary anomalies and malignant tumors. The very few worms which recover spontaneously, regenerate the eliminated parts or develop sup...

journal_title：Oncology

authors： Chandebois R

更新日期：1975-01-01 00:00:00

abstract：:We report a rare case of a patient with an intrasplenic malignant fibrous histiocytoma (MFH) and chronic myelogenous leukemia. The neoplasms were synchronous in their onset and evolution. The peculiarity of the primary site of the MFH, the genetic implications of multiple primary tumors in a single patient, and the co...

journal_title：Oncology

authors： Bonilla F,Provencio M,Fernandez E,España P

更新日期：1994-09-01 00:00:00

abstract：:Primary fetal rat fibroblasts (FRF cells) were transfected with DNA extracted from BKV-transformed hamster kidney cells at low passage after transformation (HKBKlp cells) and at high passage after transformation (HKBKhp cells). Two transformed rat cell lines were obtained, FRF-DNA-HKBKlp cells and FRF-DNA-HKBKhp cells...

journal_title：Oncology

authors： Possati L,Collesi A,Rosciani C,Rubini C

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Gemcitabine monotherapy is the cornerstone of the treatment of patients suffering from advanced pancreatic cancer (PC). For a few years, new chemotherapeutic agents and combinations have been under validation. The use of such treatment makes it necessary to determine factors that could predict survival time....

journal_title：Oncology

authors： Maréchal R,Demols A,Gay F,De Maertelaere V,Arvanitaki M,Hendlisz A,Van Laethem JL

更新日期：2007-01-01 00:00:00

abstract：:While central ports are located at the chest, peripheral ports (PP) are inserted at the patients' forearms. Two new PPs (Healthport miniMax((R)) and Bard Titan Low Profile Port) and two well-established types (Port-A-Cath((R)) P.A.S. Port and PeriPort(TM) peripheral access system) were tested. 125 patients were given ...

journal_title：Oncology

authors： Lersch C,Eckel F,Sader R,Paschalidis M,Zeilhofer F,Schulte-Frohlinde E,Theiss W

更新日期：1999-11-01 00:00:00

abstract：:Expression of ras p21 in human gastric cancers, benign lesions and normal tissues was immunohistochemically evaluated by the avidin-biotin peroxidase complex (ABC) method with anti-ras p21 monoclonal antibody rp-28. Positive p21 immunoreactivity was shown in 23 (77%) of 30 gastric cancers, in 13 (48%) of 27 benign les...

journal_title：Oncology

authors： Nakajima K,Kuzumaki N,Oda A,Kobayashi H,Katoh H,Tanabe T

更新日期：1989-01-01 00:00:00

abstract：:Capecitabine is converted to 5-fluorouracil by thymidine phosphorylase, and mitomycin C is capable of upregulating the expression of thymidine phosphorylase suggesting a synergistic effect. Fifty-three patients (median age 62 years) with anthracycline- and taxane-resistant, metastatic breast cancer received mitomycin ...

journal_title：Oncology

authors： Massacesi C,La Cesa A,Marcucci F,Pilone A,Rocchi MB,Zepponi L,Santini D,Tonini G,Burattini L

更新日期：2006-01-01 00:00:00

abstract：:In the 2010 version of the Japan Society of Hepatology (JSH) consensus-based treatment algorithm for the management of hepatocellular carcinoma (HCC), transarterial chemoembolization (TACE) failure/refractoriness was defined assuming the use of superselective lipiodol TACE, which has been widely used worldwide and par...

journal_title：Oncology

authors： Kudo M,Matsui O,Izumi N,Kadoya M,Okusaka T,Miyayama S,Yamakado K,Tsuchiya K,Ueshima K,Hiraoka A,Ikeda M,Ogasawara S,Yamashita T,Minami T,Liver Cancer Study Group of Japan.

更新日期：2014-01-01 00:00:00

abstract：:Twenty-seven patients with advanced measurable colorectal carcinoma were treated with a combination protocol consisting of folinic acid (FA) 200 mg/m2 i.v. bolus followed by 5-fluorouracil (5-FU) 550 mg/m2, and cisplatin (CIS) 20 mg/m2 each administered as a 2-hour i.v. infusion. Treatment was given on 4 consecutive d...

journal_title：Oncology

authors： Scheithauer W,Depisch D,Schiessel R,Ludwig H

更新日期：1989-01-01 00:00:00

abstract：:Information technology (IT) can enhance or change many scenarios in cancer research for the better. In this paper, we introduce several examples, starting with clinical data reuse and collaboration including data sharing in research networks. Key challenges are semantic interoperability and data access (including data...

journal_title：Oncology

authors： Ahlbrandt J,Lablans M,Glocker K,Stahl-Toyota S,Maier-Hein K,Maier-Hein L,Ückert F

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:18F-fluorodeoxyglucose positron emission tomography (FDG-PET) is useful for differentiating benign from malignant lesions, evaluating tumor stage, monitoring the response to therapy and detecting tumor recurrence in a variety of malignancies. Nevertheless, its use in patients with hepatocellular carcinoma (H...

journal_title：Oncology

authors： Yoon KT,Kim JK,Kim DY,Ahn SH,Lee JD,Yun M,Rha SY,Chon CY,Han KH

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Adenocarcinoma is the most frequent pathological type of stomach cancer. Hodgkin's lymphoma is a lymphoproliferative disease arising from lymphoid tissue which is characterized by Reed-Sternberg cells. Synchronous occurrence of these two malignancies has not been reported in the English literature so far. C...

journal_title：Oncology

authors： Comez G,Pehlivan Y,Kalender ME,Sevinc A,Sari I,Camci C

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:Esophagogastric cancer occurs more frequently in older patients, but these are underrepresented in clinical studies establishing the current treatment standards for perioperative chemotherapy in locally advanced disease. This leads to uncertainty regarding the treatment of older patients with potentially toxi...

journal_title：Oncology

authors： Haag GM,Byl A,Jäger D,Berger AK

更新日期：2017-01-01 00:00:00

abstract：:A patient seen at presentation for Hodgkin's disease (HD) at stage IV B was successfully treated with MOPP. In remission he developed coeliac disease, controlled by dietary measures, but 26 months after the end of chemotherapy a severe dyspeptic syndrome appeared; endoscopy and barium meal suggested the presence of a ...

journal_title：Oncology

authors： Eridani S,Singh AK

更新日期：1986-01-01 00:00:00