Prognostic relevance of MMP-2 (72-kD collagenase IV) in gastric cancer.

abstract：:Rapid advances in our understanding of the biology and pathology of lymphoproliferative disorders, permitted mainly by new diagnostic tools, constantly change our approach to this heterogenous group of disorders. In this review of the more indolent subgroup of lymphoproliferative disorders, some of the recent advances...

journal_title：Oncology

authors： Eek R,Falkson G

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:Cisplatin-pemetrexed combination chemotherapy is the current standard primary treatment for malignant pleural mesothelioma (MPM). It was first approved for untreated and unresectable MPM in the 2003 National Comprehensive Cancer Network (NCCN) guidelines. However, to date, standard treatments for patients wi...

journal_title：Oncology

authors： Koda Y,Kuribayashi K,Doi H,Kitajima K,Nakajima Y,Ishigaki H,Nakamura A,Minami T,Takahashi R,Yokoi T,Kijima T

更新日期：2020-10-14 00:00:00

abstract：:The expression of the drug resistance markers P glycoprotein (P-170), glutathione S transferase-pi (GST-pi) and DNA topoisomerase II (Topo II) was analyzed in 16 human kidney carcinoma cell lines, 18 hematological malignancies, and 14 human breast carcinomas. We found a tendency for coexpression of increased P-170 and...

journal_title：Oncology

authors： Efferth T,Mattern J,Volm M

更新日期：1992-01-01 00:00:00

abstract：:14 patients developed acute nonlymphocytic leukemia and 1 patient developed Burkitt's leukemia following longterm chemotherapy and/or radiotherapy for other disorders. The main primary disorders included multiple myeloma, Hodgkin's disease, non-Hodgkin's lymphoma and breast carcinoma. Acute leukemia developed earlier ...

journal_title：Oncology

authors： Brenner B,Carter A,Sharon R,Tatarsky I

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess the use of 5-fluorouracil (5-FU), leucovorin and oxaliplatin (FOLFOX) regimens in clinical practice according to their efficacy and toxicity. METHODS:Patients who received oxaliplatin-containing regimens after curative resection for colorectal carcinoma from 10 different o...

journal_title：Oncology

authors： Uncu D,Aksoy S,Çetin B,Yetişyiğit T,Özdemir N,Berk V,Dane F,Inal A,Harputluoğlu H,Budakoğlu B,Koca D,Sevinç A,Cihan S,Durnalı AG,Özkan M,Öztürk MA,Işıkdoğan A,Büyükberber S,Benekli M,Köş T,Alkış N,Karaca H,Tur

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Both irinotecan (CPT) and paclitaxel (Pac) are effective against non-small cell lung cancer (NSCLC), and besides, preclinical studies have demonstrated an additive or synergistic interaction between camptothecin and taxane. METHODS:We conducted a phase I/II study of combination chemotherapy consisting of Pa...

journal_title：Oncology

authors： Yamada K,Ikehara M,Tanaka G,Nomura I,Oshita F,Noda K

更新日期：2004-01-01 00:00:00

abstract：:23 patients received cis-platinum, doxorubicin and cyclophosphamide for gynecologic malignancy between December 1, 1980 and December 1, 1982. Each patient was randomized with each course of chemotherapy to receive intravenous droperidol or the combination of promethazine and chlorpromazine rectal suppositories as an a...

journal_title：Oncology

authors： Roberts WS,Wisniewski BJ,Cavanagh D,Marsden DE

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:We investigated the efficacy of risk-adapted adjuvant paclitaxel/carboplatin chemotherapy in early-stage ovarian carcinoma. METHODS:Fifty-three patients were treated according to the risk of relapse: patients with stages IA or IB or with grade 1 (low risk) received 4 cycles of paclitaxel and carboplatin; pat...

journal_title：Oncology

authors： Bamias A,Bamia C,Karadimou A,Soupos N,Zagouri F,Rodolakis A,Haidopoulos D,Vlahos G,Thomakos N,Antsaklis A,Dimopoulos MA

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Adenocarcinoma is the most frequent pathological type of stomach cancer. Hodgkin's lymphoma is a lymphoproliferative disease arising from lymphoid tissue which is characterized by Reed-Sternberg cells. Synchronous occurrence of these two malignancies has not been reported in the English literature so far. C...

journal_title：Oncology

authors： Comez G,Pehlivan Y,Kalender ME,Sevinc A,Sari I,Camci C

更新日期：2007-01-01 00:00:00

abstract：:Aromatase inhibitor (AI) is widely used as an endocrine treatment in postmenopausal patients with hormone receptor-positive breast cancer. To identify useful prognostic factors for patients with metastatic breast cancer treated with AI therapy, we investigated the association between several hormone receptor-related f...

journal_title：Oncology

authors： Motomura K,Ishitobi M,Komoike Y,Koyama H,Nagase H,Inaji H,Noguchi S

更新日期：2010-01-01 00:00:00

abstract：AIMS:We investigated the relationship between serum leptin concentrations and polymorphism of the leptin receptor gene and breast cancer. METHODS:Serum leptin concentrations were measured by enzyme-linked immunosorbent assay in 47 women with invasive breast cancer compared with 41 age-matched controls without cancer. ...

journal_title：Oncology

authors： Liu CL,Chang YC,Cheng SP,Chern SR,Yang TL,Lee JJ,Guo IC,Chen CP

更新日期：2007-01-01 00:00:00

abstract：:Lonidamine alone or in combination with hyperthermic perfusion, with or without melphalan, was investigated in 12 patients with stage II, III, and IV malignant melanoma. The authors evaluated the most effective methods and sequence of Lonidamine administration. Preliminary results suggest that the highest effectivenes...

journal_title：Oncology

authors： Cavaliere R,Di Filippo F,Varanese A,Carlini S,Calabro A,Aloe L,Piarulli L

更新日期：1984-01-01 00:00:00

abstract：:Repeated ultraviolet light (UV) irradiation on the skin of rats caused ulceration, scarring and epithelial tumors; 38% of the animals had ear tumors and 5% skin tumors. Guinea pigs presented minimal evidence of neoplastic transformation; only two tumors were seen while hamsters displayed localized epidermal hyperplasi...

journal_title：Oncology

authors： Stenbäck F

更新日期：1975-01-01 00:00:00

abstract：:Expression of ras p21 in human gastric cancers, benign lesions and normal tissues was immunohistochemically evaluated by the avidin-biotin peroxidase complex (ABC) method with anti-ras p21 monoclonal antibody rp-28. Positive p21 immunoreactivity was shown in 23 (77%) of 30 gastric cancers, in 13 (48%) of 27 benign les...

journal_title：Oncology

authors： Nakajima K,Kuzumaki N,Oda A,Kobayashi H,Katoh H,Tanabe T

更新日期：1989-01-01 00:00:00

abstract：:CA 19-9 and tissue polypeptide antigen (TPA) were determined in the sera of 28 control subjects, 29 patients with pancreatic cancer, 26 with chronic pancreatitis and 62 with benign and malignant extra pancreatic diseases in order to compare their usefulness in diagnosing pancreatic cancer, to verify whether the combin...

journal_title：Oncology

authors： Basso D,Fabris C,Del Favero G,Panucci A,Plebani M,Angonese C,Leandro G,Dodi G,Burlina A,Naccarato R

更新日期：1988-01-01 00:00:00

abstract：:A transplantable transitional cell murine bladder tumor induced by N-[4-(5-nitro-2-furyl)-thiazolyl] formamide (FANFT) was characterized by tumor growth, survival time and response to chemotherapy drugs, cis-dichloro-trans-dihydroxy-bis-iso-propylamine platinum IV (CHIP), cis- diaminedichloro platinum II (DDP), cyclop...

journal_title：Oncology

authors： Murphy GP,Pontes JE,Williams PD

更新日期：1984-01-01 00:00:00

abstract：:As the antitumor activity of radiation is mediated via its interaction with oxygen to form labile free radicals, the intratumoral oxygen level has an important influence on the ability of radiation therapy to kill malignant cells. By decreasing the oxygen-carrying capacity of the blood, anemia may result in tumor hypo...

journal_title：Oncology

authors： Harrison LB,Shasha D,Homel P

更新日期：2002-01-01 00:00:00

abstract：:We developed a new transcutaneous method for breast cancer detection with dogs: 2 dogs were trained to sniff skin secretion samples on compresses that had been worn overnight by women on their breast, and to recognize a breast cancer sample among 4 samples. During the test, the dogs recognized 90.3% of skin secretion ...

journal_title：Oncology

authors： Thuleau A,Gilbert C,Bauër P,Alran S,Fourchotte V,Guillot E,Vincent-Salomon A,Kerihuel JC,Dugay J,Semetey V,Kriegel I,Fromantin I

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:Serrated adenoma (SA) consists of glands both with intraluminal projection of tall columnar cells, which resemble the terminally differentiated cells in the surface epithelium, and with concave short cells, which resemble progenitor crypt cells of the colon. The aim of this study was to clarify the relationsh...

journal_title：Oncology

authors： Jiao YF,Nakamura S,Sugai T,Yamada N,Habano W

更新日期：2008-01-01 00:00:00

abstract：:The treatment of metastatic renal cell carcinoma (MRCC) has evolved from being predominantly cytokine-based to being grounded in the use of drugs targeting vascular endothelial growth factor, platelet-derived growth factor and mammalian target of rapamycin (mTOR) pathways. New agents including the small-molecule targe...

journal_title：Oncology

authors： Di Lorenzo G,Scagliarini S,Di Napoli M,Scognamiglio F,Rizzo M,Carteni' G

更新日期：2009-01-01 00:00:00

abstract：:Persistent infection with hepatitis C virus (HCV) is a major risk for the development of hepatocellular carcinoma (HCC). One of the characteristics of HCV infection is the unusual augmentation of oxidative stress, which is exacerbated by iron accumulation in the liver, as observed frequently in hepatitis C patients. U...

journal_title：Oncology

authors： Fujinaga H,Tsutsumi T,Yotsuyanagi H,Moriya K,Koike K

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:To investigate the role of adjuvant radiation therapy in locoregional control in patients with locoregionally advanced papillary thyroid carcinoma (pT4 or pN1b) based on a comparison of a group that received radiation therapy and a group that did not receive radiation therapy. METHODS:A retrospective analys...

journal_title：Oncology

authors： Lee NK,Kim CY,Baek SK,Jung KY

更新日期：2016-01-01 00:00:00

abstract：:Systemic chemotherapy for advanced gastric cancer is frequently associated with significant treatment-related toxicity, which is particularly serve in patients presenting with a poor general condition. A search for effective and low-toxic regimens for this group of patients is mandatory. A weekly 24-hour infusion of h...

journal_title：Oncology

authors： Hsu CH,Yeh KH,Chen LT,Liu JM,Jan CM,Lin JT,Chen YC,Cheng AL

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:The clinical features of hepatocellular carcinoma (HCC) differ in patients with and without cirrhosis. OBJECTIVE:We aimed to investigate the long-term outcomes of noncirrhotic HCC patients after curative resection. METHODS:We retrospectively examined 649 consecutive patients with HCC who underwent curative...

journal_title：Oncology

authors： Lee HW,Choi GH,Kim DY,Park YN,Kim KS,Choi JS,Ahn SH,Han KH

更新日期：2017-01-01 00:00:00

abstract：:The expression of cyclin-dependent kinase 1 (cdc2), cyclin A and cyclin B1 was immunohistochemically studied in 101 hepatocellular carcinomas (HCC). cdc2 overexpression was directly related to advanced stage, portal invasion, intrahepatic metastasis, poor differentiation, high alpha-fetoprotein level, large size, high...

journal_title：Oncology

authors： Ito Y,Takeda T,Sakon M,Monden M,Tsujimoto M,Matsuura N

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:Uveal melanoma primarily metastasizes hematogenously with metastases often confined to the liver. The aim of this study was to investigate the presence of circulating tumor cells (CTC) in patients with metastatic disease as a marker for systemic disease and to determine their prognostic relevance. METHODS:Bl...

journal_title：Oncology

authors： Schuster R,Bechrakis NE,Stroux A,Busse A,Schmittel A,Thiel E,Foerster MH,Keilholz U

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:Angiogenesis plays an important role in ovarian cancer. The interaction of platelet-derived growth factor receptor-beta (PDGFR-β) with vascular endothelial growth factor (VEGF) in the process of angiogenesis may represent an essential feature in the progression of the disease. METHODS:Patients with epitheli...

journal_title：Oncology

authors： Mathey S,Graeser MK,Zu Eulenburg C,Woelber L,Trillsch F,Jaenicke F,Müller V,Milde-Langosch K,Mahner S

更新日期：2013-01-01 00:00:00

abstract：:Between June 1980 and December 1984, 88 patients with stage III-IV ovarian carcinoma were entered in a study evaluating the role of debulking surgery and chemotherapy consisting of cyclophosphamide, doxorubicin, and cisplatin intravenously on day 1, every 4 weeks (CAP-1). The results after a median follow-up of 62 mon...

journal_title：Oncology

authors： Wils JA

更新日期：1990-01-01 00:00:00

abstract：:Using a Gompertzian pharmacodynamic model, we have studied the changes induced by graded doses of adriamycin (AM) on the growth of intramuscular Lewis lung carcinoma (3LL) and its lung metastases in C57Bl/6 mice. An interpretation of the drug's effects on free growth of the tumor cells is given in the Appendix. Unlike...

journal_title：Oncology

authors： Madonna M,Colombo T,Donelli MG,Dagnino G

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVE:It was the aim of our study to evaluate the efficacy and safety of weekly topotecan in patients with advanced or recurrent cervical disease. METHODS:Topotecan was administered intravenously as a weekly infusion at a dose of 3.5 mg/m(2) on days 1, 8 and 15 of a 28-day cycle. After the second cycle, the dose w...

journal_title：Oncology

authors： Lorusso D,Mainenti S,Pietragalla A,Fusco E,Malaguti P,Masciullo V,Scambia G

更新日期：2011-01-01 00:00:00