Abstract:
:23 patients received cis-platinum, doxorubicin and cyclophosphamide for gynecologic malignancy between December 1, 1980 and December 1, 1982. Each patient was randomized with each course of chemotherapy to receive intravenous droperidol or the combination of promethazine and chlorpromazine rectal suppositories as an antiemetic regimen. Both the rate and duration of emesis were significantly lower when droperidol was used as the antiemetic regimen. There were no major side effects with either regimen. Droperidol seems to be superior to the combination of promethazine and chlorpromazine rectal suppositories in alleviating cis-platinum-induced nausea and vomiting.
journal_name
Oncologyjournal_title
Oncologyauthors
Roberts WS,Wisniewski BJ,Cavanagh D,Marsden DEdoi
10.1159/000225997subject
Has Abstractpub_date
1985-01-01 00:00:00pages
42-3issue
1eissn
0030-2414issn
1423-0232journal_volume
42pub_type
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