Relapse of Hodgkin's disease after ten years.

abstract：:Novel human estrogen receptor (ER)-beta was identified in cDNA libraries from human testis. ER-beta specifically expresses in testis, ovary, thymus, spleen, osteoblasts and fetus. ER-beta might not conserve the same physiological functions as does ER-alpha. Therefore, the clinical significance of the expression of ER-...

journal_title：Oncology

authors： Fujimoto J,Hirose R,Sakaguchi H,Tamaya T

更新日期：2000-05-01 00:00:00

abstract：:As the antitumor activity of radiation is mediated via its interaction with oxygen to form labile free radicals, the intratumoral oxygen level has an important influence on the ability of radiation therapy to kill malignant cells. By decreasing the oxygen-carrying capacity of the blood, anemia may result in tumor hypo...

journal_title：Oncology

authors： Harrison LB,Shasha D,Homel P

更新日期：2002-01-01 00:00:00

abstract：:Zinostatin stimalamer (SMANCS) is a lipophilic intra-arterial chemotherapeutic agent for hepatocellular carcinoma (HCC). In our previous study, transcatheter arterial infusion chemotherapy using SMANCS for HCC showed a response rate of 20%. In an effort to obtain a superior anti-tumor effect against HCC, we conducted ...

journal_title：Oncology

authors： Okusaka T,Okada S,Ueno H,Ikeda M,Iwata R,Furukawa H,Takayasu K,Moriyama N,Sato T,Sato K

更新日期：2002-01-01 00:00:00

abstract：:Fourteen patients with advanced ovarian carcinoma (FIGO stages III-IV) resistant to cisplatin were submitted to an alternating regimen with doxorubicin (A), cyclophosphamide (C), bleomycin (B) and mitomycin C (M). All patients had measurable disease on entry into the study. No responses were observed while 3 patients,...

journal_title：Oncology

authors： Benedetti Panici P,Scambia G,Greggi S,Salerno G,Cento R,Mancuso S

更新日期：1990-01-01 00:00:00

abstract：:The local immunologic phenomena in the thyroid gland of 16 patients with chronic lymphocytic thyroiditis (CLTH) were investigated; 5 of these cases were associated with thyroid non-Hodgkin's lymphomas (NHL). All patients were admitted because of struma, growing slowly in patients with CLTH alone and rapidly in those w...

journal_title：Oncology

authors： Aozasa K,Tajima K,Tominaga N,Katagiri S,Yonezawa T,Matsuzuka F,Kuma K,Sawada M

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVES:This study aimed to evaluate any correlations between baseline creatinine clearance and the development of grade 3/4 toxicities during treatment within oncology phase I trials of molecularly targeted agents where entry criteria mandate a serum creatinine of ≤ 1.5 × the upper limit of normal. METHODS:Documen...

journal_title：Oncology

authors： Basu B,Vitfell-Pedersen J,Moreno Garcia V,Puglisi M,Tjokrowidjaja A,Shah K,Malvankar S,Anghan B,de Bono JS,Kaye SB,Molife LR,Banerji U

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:To examine the efficacy and prognostic benefits of radiotherapy (RT) in patients who have unresectable advanced hepatocellular carcinoma (HCC) with invasion to intrahepatic large vessels (IHLVs). METHODS:Sixty-eight patients who had advanced HCC with invasion to IHLVs were studied. Thirty-two consecutive pa...

journal_title：Oncology

authors： Nakazawa T,Adachi S,Kitano M,Isobe Y,Kokubu S,Hidaka H,Ono K,Okuwaki Y,Watanabe M,Shibuya A,Saigenji K

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to evaluate the antitumor activity and safety of an epirubicin, cisplatin, and capecitabine (ECX) combination in patients with metastatic or advanced gastric cancer. PATIENTS AND METHODS:Patients with metastatic or advanced measurable gastric adenocarcinoma received ECX combina...

journal_title：Oncology

authors： Cho EK,Lee WK,Im SA,Lee SN,Park SH,Bang SM,Park DK,Park YH,Shin DB,Lee JH

更新日期：2005-01-01 00:00:00

abstract：:In patients affected with different tumours, disorders concerning clotting are frequently observed. The biological processes leading to coagulation are probably involved in the mechanisms of metastasis. We studied plasma levels of thrombin-antithrombin III complexes (TAT) in 90 patients affected with lung tumours subg...

journal_title：Oncology

authors： Tricerri A,Vangeli M,Errani AR,Guidi L,Canetta M,Vaccarino M,De Santis C,Ipsevich F,Salvati F,Bartoloni C

更新日期：1996-11-01 00:00:00

abstract：INTRODUCTION:Because the frequency of bile duct invasion in hepatocellular carcinoma (HCC) patients is very rare, there is limited clinical evidence to demonstrate the outcomes of systemic therapy in HCC with bile duct invasion. OBJECTIVE:Our aim was to clarify the efficacy and safety of sorafenib treatment in patient...

journal_title：Oncology

authors： Tanaka T,Kuzuya T,Ishigami M,Ito T,Ishizu Y,Honda T,Ishikawa T,Fujishiro M

更新日期：2020-01-01 00:00:00

abstract：:The antiemetic effect of graded, single high-dose intravenous dexamethasone was studied in 27 patients receiving combination chemotherapy with either doxorubicin (50 mg/m2) or cis-platinum (100 mg/m2). A total of 57 cycles were individually evaluated, utilizing a detailed rating system. Nausea and vomiting did not occ...

journal_title：Oncology

authors： Zaglama NE,Rosenblum SL,Sartiano GP,Brady M,Gonzalez MF,Valdivieso JG

更新日期：1986-01-01 00:00:00

abstract：:The energy status of HeLa cells arrested in the G2 phase of the cell cycle by the antineoplastic agent cis-acid was compared with that of normal G2-phase-synchronized cells. The results showed that treatment with the drug has significantly decreased the adenylate pool, adenylate energy charge and phosphorylation poten...

journal_title：Oncology

authors： Al-Awadi FM,Al-Bader AA

更新日期：1987-01-01 00:00:00

abstract：:The present study was undertaken to detect the spontaneous mammary tumor-associated antigen ( MTAA ), and to find the cross-reacting antigen in chemically-induced mammary tumor. The antisera against spontaneous mammary tumor were raised in the WAF1 rats of the same strain and tested for the detection of tumor-associat...

journal_title：Oncology

authors： Imamura N,Yanagihara K,Kusunoki Y

更新日期：1984-01-01 00:00:00

abstract：:Human papillomaviruses (HPVs) have been linked to a variety of human diseases, most notably cancer of the cervix. In the majority of cases, HPV proteins E6 and E7 are continuously expressed and bind a variety of cellular proteins. The precise mechanism of HPV-induced carcinogenesis has not been fully elucidated; there...

journal_title：Oncology

authors： Yaginuma Y,Yoda K,Ogawa K

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of percutaneous cementoplasty for painful bone metastasis from hepatocellular carcinoma (HCC). METHODS:Cementoplasty was performed for 22 metastatic bone tumors in 13 patients. All patients had intractable pain and were diagnosed as metastatic bone tumor from HCC. The ostyneedle was in...

journal_title：Oncology

authors： Kodama H,Aikata H,Uka K,Takaki S,Mori N,Waki K,Jeong SC,Kawakami Y,Shirakawa H,Takahashi S,Toyota N,Ito K,Chayama K

更新日期：2007-01-01 00:00:00

abstract：:A model system for studying some aspects of the interaction of cancer cells in tumors and their surrounding nonmalignant tissue is the co-culture of cancer cells and embryonic chick neural retinal cells in gyratory shakers. Neural retina cell aggregation, under these conditions, has been shown to be differentially inh...

journal_title：Oncology

authors： Maslow DE,Mayhew E,Mittleman A

更新日期：1981-01-01 00:00:00

abstract：:Further biochemical characterization of the Albert hepatoma has been performed. The following results were obtained: In spite of often repeated transplantations and a medium growth rate, the Albert hepatoma does still contain organ-characteristic enzymes. We have found significant activities of glucokinase, glucose-6-...

journal_title：Oncology

authors： Sydow G

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Sorafenib, a multitargeted tyrosine kinase inhibitor, is now the treatment of choice for systemic therapy of patients with advanced hepatocellular carcinoma (HCC). Herein, we present the clinical characteristics and outcomes of patients with advanced HCC who were treated with sorafenib. METHODS:Data of 201 ...

journal_title：Oncology

authors： Baek KK,Kim JH,Uhm JE,Park SH,Lee J,Park JO,Park YS,Kang WK,Lim HY

更新日期：2011-01-01 00:00:00

abstract：:2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), the most abundant food-derived mutagenic/carcinogenic heterocyclic amine (HCA), has attracted particular attention as a probable human colon carcinogen. Some studies have shown that PhIP administered in the post-initiation phase is able to enhance rat colon carci...

journal_title：Oncology

authors： Doi K,Hagihara A,Wei M,Yunoki T,Fukushima S,Wanibuchi H

更新日期：2007-01-01 00:00:00

abstract：:We have studied the effect of butyrate on mammary tumorigenesis by 7,12-dimethylbenz(a)anthracene. As reported previously, a high incidence of mammary tumors was observed in rats fed a basal diet containing 20% margarine. However, the enhancing effect of margarine was inhibited when sodium butyrate was supplemented in...

journal_title：Oncology

authors： Yanagi S,Yamashita M,Imai S

更新日期：1993-07-01 00:00:00

abstract：:Gastric epithelial cells, identified in biopsy specimens from individuals with varying degrees of gastritis and cellular atypia, were classified according to morphology and reactivity with an adult tissue-absorbed rabbit antibody to 2nd trimester human fetal tissue. Sections of stomach from normal individuals and pati...

journal_title：Oncology

authors： Higgins PJ,Correa P,Cuello C,Lipkin M

更新日期：1984-01-01 00:00:00

abstract：:CA 19-9 and tissue polypeptide antigen (TPA) were determined in the sera of 28 control subjects, 29 patients with pancreatic cancer, 26 with chronic pancreatitis and 62 with benign and malignant extra pancreatic diseases in order to compare their usefulness in diagnosing pancreatic cancer, to verify whether the combin...

journal_title：Oncology

authors： Basso D,Fabris C,Del Favero G,Panucci A,Plebani M,Angonese C,Leandro G,Dodi G,Burlina A,Naccarato R

更新日期：1988-01-01 00:00:00

abstract：:Peripheral blood T-cell subsets of 70 patients with untreated gastric cancer and 55 age- and sex-matched normal controls were studied by using monoclonal antibodies and flow cytometry. The number of T cells (Leu 4+ cells) was significantly decreased in stage IV patients. Statistically significant decreases in the numb...

journal_title：Oncology

authors： Watanabe T,Nakauchi H,Kitaoka H,Matsuki K,Okumura K,Nomura K,Takakura K

更新日期：1985-01-01 00:00:00

abstract：:As TS-1 and docetaxel (TXT) have different mechanisms of antitumor activity, the combination therapy is expected to have a higher response. Human gastric cancer xenografts SC-2, St-40, and SC-4 inoculated into nude rats were treated with TS-1 alone (TS-1 12 mg/kg/day, day 1-14), TXT alone (TXT 2 mg/kg/day, day 1 or da...

journal_title：Oncology

authors： Takahashi I,Emi Y,Kakeji Y,Uchida J,Fukushima M,Maehara Y

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Patients with localized gastric adenocarcinoma (LGAC), who get pre-operative therapy, have heterogeneous/unpredictable outcomes. Predictive clinical variables/biomarkers are not established. METHODS:We analyzed 107 LGAC patients who had chemoradiation and surgery. LGACs were grouped for (1) presence/absence...

journal_title：Oncology

authors： Charalampakis N,Nogueras González GM,Elimova E,Wadhwa R,Shiozaki H,Shimodaira Y,Blum MA,Rogers JE,Harada K,Matamoros A Jr,Sagebiel T,Das P,Minsky BD,Lee JH,Weston B,Bhutani MS,Estrella JS,Badgwell BD,Ajani JA

更新日期：2016-01-01 00:00:00

abstract：:In 35 children with acute lymphatic or undifferentiated leukemia, immunological properties of normal lymphocytes and lymphoblasts were investigated. In most cases the number of circulating normal lymphocytes with surface or B markers and delayed type hypersensitivity was depressed. On the other hand, the response to m...

journal_title：Oncology

authors： Winterleitner H,Rella W,Eibl M,Krepler P

更新日期：1978-01-01 00:00:00

abstract：:The relationship of vitamins to cancer is very complex. Three types of interactions are possible: the effect of vitamins on tumor growth, the effect of tumors on vitamin metabolism, and the effect of vitamins on chemical carcinogens and anti-tumor chemotherapeutic agents. The significance of vitamins with particular r...

journal_title：Oncology

authors： Basu TK

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:The Oncotype DX Breast Cancer Assay is a 21-gene assay used to predict the likelihood of distant recurrence and the benefit of chemotherapy in patients with node-negative, tamoxifen-treated breast cancer. Prior studies demonstrated 7-19% discordance, or a difference between the recurrence score (RS) and tumo...

journal_title：Oncology

authors： Blanter J,Zimmerman B,Tharakan S,Ru M,Cascetta K,Tiersten A

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:Irinotecan has, in general, been administered as a 90-min infusion. However, several studies have demonstrated that continuous infusion seems to be a promising method of delivering irinotecan. This phase I/II trial was performed to evaluate the efficacy and safety of continuous infusion of irinotecan combined...

journal_title：Oncology

authors： Sadahiro S,Suzuki T,Maeda Y,Tanaka A,Ishikawa K,Makuuchi H,Murayama C

更新日期：2009-01-01 00:00:00

abstract：:To determine the relationship between neoplastic transformation and increased genetic instability, spontaneous and induced mutation rates were compared in a nontumorigenic, immortalized human bronchial epithelial cell line (NL20) and a tumorigenic cell line (NL20T) spontaneously derived from the NL20 line. Using the h...

journal_title：Oncology

authors： Wittenkeller JL,Storer B,Bittner G,Schiller JH

更新日期：1997-07-01 00:00:00