Abstract:
:Magnetic resonance imaging-guided laser interstitial thermal therapy (LITT) is a minimally invasive treatment modality with recent increasing use to ablate brain tumors. When originally introduced in the late 1980s, the inability to precisely monitor and control the thermal ablation limited the adoption of LITT in neuro-oncology. Popularized as a means of destroying malignant hepatic and renal metastatic lesions percutaneously, its selective thermal tumor destruction and preservation of adjacent normal tissues have since been optimized for use in neuro-oncology. The progress made in real-time thermal imaging with MRI, laser probe design, and computer algorithms predictive of tissue kill has led to the resurgence of interest in LITT as a means to ablate brain tumors. Current LITT systems offer a surgical option for some inoperable brain tumors. We discuss the origins, principles, current indications, and future directions of MRI-guided LITT in neuro-oncology.
journal_name
Oncologyjournal_title
Oncologyauthors
Rahmathulla G,Recinos PF,Kamian K,Mohammadi AM,Ahluwalia MS,Barnett GHdoi
10.1159/000362817subject
Has Abstractpub_date
2014-01-01 00:00:00pages
67-82issue
2eissn
0030-2414issn
1423-0232pii
000362817journal_volume
87pub_type
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