Abstract:
:Cancer pain management had received relatively little attention until the late 1990s, when approximately 100,000 new cancer cases and 60,000 cancer deaths occurred each year in Korea. In 2001, a Cancer Pain Management Guideline was prepared for the first time by the Korean Society of Hospice and Palliative Care. This guideline facilitated cancer pain management by health professionals since then. In addition, cancer pain management has been included in the regular curriculum of all medical schools in Korea. The Korean Cancer Pain Assessment Tool, which was developed in 2003, has been accepted as a reliable and valid instrument for assessing cancer pain in Korea. The Korean version of quality of life assessment tools has also been accepted as a useful method. Oral short-acting opioids became available, along with other effective and convenient opioid drugs. The Korean government first published the Cancer Pain Management Guideline for health care professionals in 2004 and expanded the medical reimbursement criteria for cancer pain management, which reflect the government's support and interest in cancer pain care. The cancer pain surveys conducted in 2001 and 2006 demonstrated a significantly increased patient satisfaction on pain control (37% in 2001, n = 3,006 vs. 42% in 2006, n = 3,737, p = 0.003). Therefore, cancer pain management has been systematically approached both by health professionals as well as the government and resulted in a vast improvement in cancer pain control.
journal_name
Oncologyjournal_title
Oncologyauthors
Lee JY,Ahn JSdoi
10.1159/000143211subject
Has Abstractpub_date
2008-01-01 00:00:00pages
4-6eissn
0030-2414issn
1423-0232pii
000143211journal_volume
74 Suppl 1pub_type
杂志文章相关文献
ONCOLOGY文献大全abstract::Beard's theory can be restated in a modified form in modern terms in the following way. Cancer represents primarily trophoblastic tissue derived either from an aberrant germ cell or from a somatic cell whose normally repressed 'asexual generation' genes are abnormally reactivated ('derepressed'). The variety of tumors...
journal_title:Oncology
pub_type: 传,历史文章,杂志文章
doi:10.1159/000225037
更新日期:1975-01-01 00:00:00
abstract:OBJECTIVE:There is much evidence for the detrimental effect of treatment interruptions on tumor control, particularly in head and neck cancer. In order to determine the outcome of the treatment interruptions in postoperative irradiation of breast cancer, 853 female patients treated between 1990 and 1999 inclusive were ...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000087909
更新日期:2005-01-01 00:00:00
abstract::Many of the previously proposed theories of carcinogenesis which relate the exposure level of a carcinogen to expected tumor response, are summarized and it is pointed out that these theories assume the existence of no threshold level. A modification of the one-hit carcinogenic model which would incorporate a threshol...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000225106
更新日期:1976-01-01 00:00:00
abstract:OBJECTIVE:Pegylated liposomal doxorubicin (PLD) and capecitabine (CAP) have separately shown significant antitumor activity in a wide range of solid tumors. A phase I study was conducted in order to determine the maximum tolerated dose (MTD) and dose-limiting toxicities (DLTs) of their combination in patients with refr...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000090494
更新日期:2005-01-01 00:00:00
abstract::Between June 1980 and December 1984, 88 patients with stage III-IV ovarian carcinoma were entered in a study evaluating the role of debulking surgery and chemotherapy consisting of cyclophosphamide, doxorubicin, and cisplatin intravenously on day 1, every 4 weeks (CAP-1). The results after a median follow-up of 62 mon...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000226801
更新日期:1990-01-01 00:00:00
abstract::72 patients with advanced malignant lymphoma resistant to standard chemotherapy were treated with 1-(2-chloroethyl)-3-cyclohexyl-l-nitrosourea (CCNU) at 130 mg/m2 orally every six weeks. Objective responses were noted in 13 of 39 evaluable patients with Hodgkin's disease, three of 15 patients with lymphocytic lymphoma...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000225162
更新日期:1976-01-01 00:00:00
abstract::The expression of cyclin-dependent kinase 1 (cdc2), cyclin A and cyclin B1 was immunohistochemically studied in 101 hepatocellular carcinomas (HCC). cdc2 overexpression was directly related to advanced stage, portal invasion, intrahepatic metastasis, poor differentiation, high alpha-fetoprotein level, large size, high...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000012140
更新日期:2000-06-01 00:00:00
abstract::Nucleophosmin/B23 is a nucleolar phosphoprotein which redistributes from nucleoli to nucleoplasm (B23-translocation) when cells are exposed to certain anticancer drugs, particularly intercalators. The B23-translocation assay has been demonstrated in cell culture to correlate with drug effects and to detect drug-resist...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000227043
更新日期:1992-01-01 00:00:00
abstract::The chemosensitivities of 62 human colon cancer tissues, 67 rectal cancer tissues and 31 tumor-adjacent normal mucosal tissues were determined using the in vitro succinate dehydrogenase inhibition (SDI) test. These tissues obtained at the time of surgery were exposed to carboquone (CQ), adriamycin (ADM), mitomycin C (...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000226917
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Osteosarcoma is a rare malignancy, and patients with this disease benefit from adjuvant chemotherapy. While cisplatin, anthracyclines and ifosfamide are the most commonly used agents in the treatment of osteosarcoma, a search for the best combination with higher efficacy and minimal toxicity continues. We pl...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000113017
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:The objective of this phase III trial was to compare chemotherapy combined with bevacizumab versus chemotherapy alone in the treatment of patients with advanced colorectal cancer. METHODS:From September 2004 till September 2008, 222 treatment-naive patients were enrolled and divided into 2 arms: 114 arm A pa...
journal_title:Oncology
pub_type: 杂志文章,随机对照试验
doi:10.1159/000320520
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:There has been no clinically useful diagnostic or prognostic biomarker for renal cell carcinoma (RCC). Serum γ-glutamyltransferase (GGT) activity has been reported to be a prognostic marker for several types of cancer including RCC. Exosomes or small extracellular vesicles present in body fluids have potenti...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000508688
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:This study aimed to evaluate any correlations between baseline creatinine clearance and the development of grade 3/4 toxicities during treatment within oncology phase I trials of molecularly targeted agents where entry criteria mandate a serum creatinine of ≤ 1.5 × the upper limit of normal. METHODS:Documen...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000341152
更新日期:2012-01-01 00:00:00
abstract::The historical aspects of drug development and evaluation are anecdotically related. Clinical trials have proven the effectiveness of animal tests in the vast majority of cases, and the effort has been well spent. Similar of more noteworthy success may be obtainable with model systems in the study of prostatic cancer....
journal_title:Oncology
pub_type: 历史文章,杂志文章
doi:10.1159/000225197
更新日期:1977-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the clinical and cost benefits of the administration of aprepitant for the prophylaxis of chemotherapy-induced nausea and vomiting (CINV) during high-dose chemotherapy (HDCT). METHODS:We retrospectively reviewed the charts of patients who received HDCT at our institution between January 2009 and ...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000479032
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:Transarterial chemoembolization (TACE) is recommended as a first-line therapy for hepatocellular carcinoma (HCC) patients ineligible for curative therapy and without portal invasion. The Assessment for Retreatment with TACE (ART) scoring system was recently proposed for identifying patients who would not show...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000440625
更新日期:2015-01-01 00:00:00
abstract::Chromosomal aberrations and sister chromatid exchanges were examined in 45 patients with nonseminomatous testicular cancer at different times after the termination of vinblastine, cisplatin and bleomycin (VPB) therapy and in 22 age-matched healthy men and untreated testicular cancer patients. After 36 months, the freq...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000226859
更新日期:1990-01-01 00:00:00
abstract::A demonstration multiphasic cancer screening program was conducted in a rural village in Thailand under the coordination of Bangkok's National Cancer Institute. The village's physician, mayor, and other members of the community assumed a variety of volunteer roles in order to provide logistical support. In short, this...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000226029
更新日期:1985-01-01 00:00:00
abstract::Canthaxanthin, a carotenoid with no vitamin A activity, was evaluated for its efficacy in the prevention of chemically induced mammary cancers. Canthaxanthin was administered in the diet at two dose levels (3,390 or 1,130 mg/kg diet). In the dimethylbenzanthracene-induced mammary cancer model, diet supplementation wit...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000226935
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:We conducted this study to compare tumor measurement by computed tomography (CT) and tumor response assessment between Response Evaluation Criteria In Solid Tumors (RECIST) 1.0 and RECIST 1.1 in patients with metastatic colorectal cancer (CRC). METHODS:We reviewed the medical records of patients with metasta...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000357714
更新日期:2014-01-01 00:00:00
abstract::6 cases of endodermal sinus tumor of the ovary are presented. In 4 patients pure endodermal sinus tumor was found microscopically. 1 patient had endodermal sinus tumor in one ovary and gonadoblastoma in the contralateral one. In another case endodermal sinus tumor was accompanied by an embryonal teratoma. Histological...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000225338
更新日期:1979-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the outcomes of gemcitabine-treated patients with inoperable biliary tract cancers. METHODS:We conducted a retrospective study of consecutively treated 22 inoperable biliary tract cancer patients with gemcitabine (500-1,000 mg/m(2) on days 1, 8, 15 every 4 weeks) as f...
journal_title:Oncology
pub_type: 杂志文章,评审
doi:10.1159/000098109
更新日期:2006-01-01 00:00:00
abstract::Sixteen patients with histologically confirmed inoperable hepatocellular carcinoma were treated with vindesine 3 mg/m2 i.v. weekly. Anemia, leukopenia and neuritis were documented but no severe or life-threatening toxicity was seen. There were no objective responses among the 14 evaluable patients. Eight had a no chan...
journal_title:Oncology
pub_type: 临床试验,杂志文章
doi:10.1159/000227434
更新日期:1995-01-01 00:00:00
abstract::In squamous cell carcinoma of the head and neck (SCCHN), hypoxia is considered a crucial physiological modulator for malignant progression, wherebythe plasminogen activation system is involved in overlapping functions such as moulding of the extracellular matrix, cell proliferation and signal transduction. Little is k...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000106789
更新日期:2006-01-01 00:00:00
abstract::23 patients received cis-platinum, doxorubicin and cyclophosphamide for gynecologic malignancy between December 1, 1980 and December 1, 1982. Each patient was randomized with each course of chemotherapy to receive intravenous droperidol or the combination of promethazine and chlorpromazine rectal suppositories as an a...
journal_title:Oncology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000225997
更新日期:1985-01-01 00:00:00
abstract:OBJECTIVE:Irinotecan has, in general, been administered as a 90-min infusion. However, several studies have demonstrated that continuous infusion seems to be a promising method of delivering irinotecan. This phase I/II trial was performed to evaluate the efficacy and safety of continuous infusion of irinotecan combined...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000209963
更新日期:2009-01-01 00:00:00
abstract::Vascular endothelial growth factor C (VEGF-C) is considered to be potentially lymphangiogenic and can selectively induce hyperplasia of the lymphatic vasculature. In this study, we clarified the clinicopathological features of early gastric carcinoma (EGC) that has metastasized to the lymph nodes, as well as the corre...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000055312
更新日期:2001-01-01 00:00:00
abstract::The effects on gastric and duodenal mucosa induced by cisplatin plus etoposide (PE) chemotherapy were investigated in 32 patients with lung cancer. They were submitted to gastroduodenoscopy before receiving cisplatin 100 mg/m2 (day 1) plus etoposide at a mean dose of 107 mg/m2 (days 1, 3 and 5). Endoscopic examination...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000226958
更新日期:1991-01-01 00:00:00
abstract::This paper reviews the effectiveness of local interleukin-2 (IL-2) therapy and its effector induction mechanisms in vivo. Local therapy with IL-2 and/or lymphokine-activated killer (LAK) cells is associated with far fewer side effects than systemic treatment. Local infusions of IL-2 into malignant pleural effusions an...
journal_title:Oncology
pub_type: 杂志文章,评审
doi:10.1159/000227331
更新日期:1994-03-01 00:00:00
abstract:OBJECTIVE:To report the outcomes of surgical resection of borderline resectable (BL) and locally advanced (LA) 'unresectable' pancreatic cancer after neoadjuvant chemotherapy. METHODS:A review of a prospectively maintained database for pancreatic resections was undertaken to identify patients undergoing resection for ...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000371745
更新日期:2015-01-01 00:00:00