Expression of N-acetylglucosaminyltransferase V in the development of human esophageal cancers: immunohistochemical data from carcinomas and nearby noncancerous lesions.

abstract：:The use of the blood-brain barrier and of tumor-specific antibodies to concentrate boron selectivity in gliomas for neutron capture therapy is considered experimentally and theoretically. The time-dependent concentration of two anionic boranes, B12 H11 SH2- and B12 H11 SOSB12 H114-, in the blood, brain, and tumor of ...

journal_title：Oncology

authors： Tolpin EI,Wellum GR,Dohan FC Jr,Kornblith PL,Zamenhof RG

更新日期：1975-01-01 00:00:00

abstract：:The effect of the differentiation-inducing agent dimethylsulfoxide (DMSO) on the protein composition of hepatic tumor cells was evaluated using the BW77-1 line of murine hepatoma cells previously determined to be DMSO-inducible for enhanced liver function. DMSO-mediated suppression of BW77-1 proliferation was accompan...

journal_title：Oncology

authors： Higgins PJ

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:This pharmacokinetic study of S-1 was conducted in patients in whom glomerular filtration rate (GFR) was directly measured to explore the possibility of adjusting the S-1 dose on the basis of GFR in patients with normal or nearly normal renal function. METHODS:S-1 was given to 12 patients twice daily for 28 ...

journal_title：Oncology

authors： Ando Y,Kawada K,Inada M,Morita S,Mitsuma A,Yasuda Y,Hiramatsu M,Fujimoto Y,Fujita K

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To better determine docetaxel activity in patients with well-defined anthracycline-resistant breast cancer. METHODS:From October 1996, we carried out a phase II trial in 69 heavily pretreated patients with advanced breast cancer with docetaxel 100 mg/m(2) by a 1-hour infusion on day 1, with cycles repeated e...

journal_title：Oncology

authors： Vici P,Belli F,Di Lauro L,Amodio A,Conti F,Foggi P,Gionfra T,Morelli MF,Botti C,Ferraironi A,Lopez M

更新日期：2001-01-01 00:00:00

abstract：:72 patients with advanced malignant lymphoma resistant to standard chemotherapy were treated with 1-(2-chloroethyl)-3-cyclohexyl-l-nitrosourea (CCNU) at 130 mg/m2 orally every six weeks. Objective responses were noted in 13 of 39 evaluable patients with Hodgkin's disease, three of 15 patients with lymphocytic lymphoma...

journal_title：Oncology

authors： Stolinsky DC,Solomon J,Weiner JM,Bateman JR

更新日期：1976-01-01 00:00:00

abstract：:A patient seen at presentation for Hodgkin's disease (HD) at stage IV B was successfully treated with MOPP. In remission he developed coeliac disease, controlled by dietary measures, but 26 months after the end of chemotherapy a severe dyspeptic syndrome appeared; endoscopy and barium meal suggested the presence of a ...

journal_title：Oncology

authors： Eridani S,Singh AK

更新日期：1986-01-01 00:00:00

abstract：:Hemostatic abnormalities are rather frequent in cancer patients either in hematological or in solid tumors. Acute disseminated intravascular coagulation (DIC) is a rare coagulopathy in cancer patients, but when it develops it becomes rapidly fatal. Between June 1988 and December 1992 we observed 8 cases of acute DIC o...

journal_title：Oncology

authors： Pasquini E,Gianni L,Aitini E,Nicolini M,Fattori PP,Cavazzini G,Desiderio F,Monti F,Forghieri ME,Ravaioli A

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Ovarian clear cell carcinoma (CCC) has a poorer prognosis than other subtypes of ovarian cancer. In this study, we evaluated the responsiveness to second-line chemotherapy in recurrent ovarian CCC. METHODS:The MITO-9 project investigated a cohort of patients observed between 1991 and 2007 in 20 cen...

journal_title：Oncology

authors： Esposito F,Cecere SC,Magazzino F,Katsaros D,Ottaiano A,Gadducci A,Pisano C,Scalone S,Rabaiotti E,Salutari V,Cormio G,Canuto EM,Greggi S,Savarese A,Marinaccio M,Scollo P,Santeufemia DA,Sacco C,Facchini G,Pignata S

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:To investigate the role of adjuvant radiation therapy in locoregional control in patients with locoregionally advanced papillary thyroid carcinoma (pT4 or pN1b) based on a comparison of a group that received radiation therapy and a group that did not receive radiation therapy. METHODS:A retrospective analys...

journal_title：Oncology

authors： Lee NK,Kim CY,Baek SK,Jung KY

更新日期：2016-01-01 00:00:00

abstract：:The present communication reports the inhibitory action of aminoglutethimide on 9,10-dimethyl-1,2-benzanthracene (DMBA) induced mammary carcinogenesis in virgin female Holtzman rats. When 20 mg of DMBA is given to the rats and maintained on normal diet for 32 weeks, approximately 70% of the animals develop mammary tum...

journal_title：Oncology

authors： Rao AR,Das MG,Das P

更新日期：1985-01-01 00:00:00

abstract：:Cyclin D3 promotes cell cycle progression but its expression and prognostic significance in human colorectal cancer is unknown. This study assayed cyclin D3 expression against cell cycle phase fraction and Duke's stage in 35 fresh human primary colorectal cancers. DNA content, cell cycle phase fraction and cyclin D3 e...

journal_title：Oncology

authors： Watson DS,Brotherick I,Shenton BK,Wilson RG,Angus B,Varma JS,Campbell FC

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:Anti-p53 levels detected by different methods were compared in a predefined group of patients with breast cancer and correlated with p53 antigen expression in the corresponding tumors. METHODS:P53 autoantibodies were investigated in 165 patients with primary breast cancer using ELISAs with recombinant or nat...

journal_title：Oncology

authors： Volkmann M,Sinn HP,Gaugel D,Frey M,Hajjar Y,Ludwig J,Hänsel S,Bastert G,Wallwiener D,Fiehn W,Zentgraf H,Huober J

更新日期：2002-01-01 00:00:00

abstract：:The role of p53, retinoblastoma (RB) and c-erbB-2 gene proteins in the pathogenesis of anal carcinomas has been examined. A total of 97 patients were included in the study. c-erbB-2, RB and p53 proteins were abnormal in 0, 5 and 34% of the cases, respectively. No correlation was observed between p53 and age, sex, tumo...

journal_title：Oncology

authors： Tanum G,Holm R

更新日期：1996-09-01 00:00:00

abstract：:Lymphomas, which are frequently subdivided into Hodgkin's disease and non-Hodgkin's lymphoma, represent one of the more curable cancers that present as a solid tumor. Unfortunately, most patients cannot be cured with conventional chemotherapy, therefore new techniques have been developed including high-dose chemothera...

journal_title：Oncology

authors： Armitage JO

更新日期：2000-04-01 00:00:00

abstract：:Lewis lung carcinoma (3LL), which has been most frequently used for various investigations of cancer, was converted to an ascitic form designated 3LL-SA. Ascites tumor cells showed a mixed population of single cells and about 10% islands which were made up of 2 to about 50 cells. Transplantability was 100%. The biolog...

journal_title：Oncology

authors： Sato T,Takusagawa K,Asoo N,Kumano N,Hasuike M,Konno K

更新日期：1989-01-01 00:00:00

abstract：:We have measures serial carcinoembryonic antigen (CEA) titers in 92 patients, randomly selected from the patient population of a Radiotherapeutic Clinic, to correlate with clinical and follow-up evaluation. 57 out of 92 patients had positive CEA levels (2.5 ng/ml) or 62 percent of proven cancer patients. In this serie...

journal_title：Oncology

authors： Vider M,Kashmiri R,Hunter L,Moses B,Meeker WR,Utley JF,Maruyama Y

更新日期：1974-01-01 00:00:00

abstract：:The effects of theophylline treatment on mouse B-16 melanoma cell growth, metabolism, and membrane antigen expression in vitro were studied. Theophylline treatment inhibited DNA synthesis and the cell growth rate, and caused an elevation of intracellular cAMP levels. Cells treated with theophylline became elongated an...

journal_title：Oncology

authors： Kolb CA,Mansfield JM

更新日期：1980-01-01 00:00:00

abstract：:The authors have reviewed the medical records of 421 sessions of hyperthermia treatments in 73 patients treated between 1987 and 1992 at the University Heights Cancer Center and the Indiana University Medical Center in Indianapolis, Ind. Temperatures attained during the course of therapy on each patient have been aver...

journal_title：Oncology

authors： Shidnia H,Hornback N,Ford G,Shen RN

更新日期：1993-09-01 00:00:00

abstract：:The aim of this study was to both develop and validate a nomogram based on the Ki-67 index to predict recurrence. We constructed a nomogram using the Cox proportional hazards model with 953 N0 and N1 postoperative hormone receptor (HR)-positive breast cancer patients and validated it in an external cohort of 895 patie...

journal_title：Oncology

authors： Park YH,Im SA,Cho EY,Ahn JH,Woo SY,Kim S,Keam B,Lee JE,Han W,Nam SJ,Park IA,Noh DY,Yang JH,Ahn JS,Im YH

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Variations in the incidence of cancer can be influenced by diet and specific lifestyles. In the last years, diet has been evaluated as an important factor in the development of ovarian cancer, even though the results have not been consistent. Dietary factors related to the risk of ovarian cancer in Mexican w...

journal_title：Oncology

authors： Salazar-Martinez E,Lazcano-Ponce EC,Gonzalez Lira-Lira G,Escudero-De los Rios P,Hernandez-Avila M

更新日期：2002-01-01 00:00:00

abstract：:Between 1986 and 1991, 35 patients with esophageal cancer (TNM stages II-IV) underwent transthoracic esophagectomy with lymph adenectomy and were subsequently treated with 5,000 cGy of radiation (days 1-40) and concurrently with two courses of chemotherapy (cisplatin, vindesine and pepleomycin, days 21-26 and 49-54). ...

journal_title：Oncology

authors： Saito T,Shigemitsu Y,Kinoshita T,Shimoda K,Abe T,Nakamura A,Chikuba K,Kobayashi M

更新日期：1993-07-01 00:00:00

abstract：:ACNU was highly effective for Sato lung carcinoma transplanted intravenously or intramuscularly by using a large single dose, and the cytotoxic action of ACNU for SLC showed clear dependence upon tumor size. Nonspecific activation of host-defence mechanism by Propionibacterium acnes contributed to the suppression for ...

journal_title：Oncology

authors： Saijo N,Niitani H,Irimajiri N,Chikama M

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to evaluate the antitumor activity and safety of an epirubicin, cisplatin, and capecitabine (ECX) combination in patients with metastatic or advanced gastric cancer. PATIENTS AND METHODS:Patients with metastatic or advanced measurable gastric adenocarcinoma received ECX combina...

journal_title：Oncology

authors： Cho EK,Lee WK,Im SA,Lee SN,Park SH,Bang SM,Park DK,Park YH,Shin DB,Lee JH

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:BRAF D594G mutations in colorectal cancer patients are not clearly understood. We retrospectively investigated the clinicopathological features of colorectal cancers with BRAF D594G mutations. METHODS:We selected 908 colorectal cancer patients who underwent surgical resection from January 2008 to January 201...

journal_title：Oncology

authors： Amaki-Takao M,Yamaguchi T,Natsume S,Iijima T,Wakaume R,Takahashi K,Matsumoto H,Miyaki M

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The therapeutic potential of chemotherapy in the treatment of recurrent or metastatic non-small cell lung carcinoma (NSCLC) seems modest. Thus, the search for novel agents and combination regimens with a superior therapeutic index has a high priority. The present combination regimen consisting of mitomycin C...

journal_title：Oncology

authors： Hejna M,Kornek GV,Raderer M,Marosi L,Schneeweiss B,Greul R,Weinländer G,Valencak J,Huber H,Scheithauer W

更新日期：1998-11-01 00:00:00

abstract：PURPOSE:In order to determine whether infection with Helicobacter pylori might be associated with pancreatic adenocarcinoma, we performed a study to compare the H. pylori seroprevalence rate between patients with pancreatic carcinoma and matched control subjects. PATIENTS AND METHODS:Blood samples from 92 patients wit...

journal_title：Oncology

authors： Raderer M,Wrba F,Kornek G,Maca T,Koller DY,Weinlaender G,Hejna M,Scheithauer W

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND AIM:In vitro, methotrexate (MTX) is the best modulator for bolus 5-fluorouracil (5FU), whereas folinic acid (FA) is the best for continuous infusion. We evaluated the effect of 5FU modulated by both MTX (bolus administration) and FA (continuous infusion) as second-line treatment of patients with metastat...

journal_title：Oncology

authors： Carlomagno C,Lauria R,De Laurentiis M,Arpino G,Massarelli E,Ferrara C,Milano A,Vernaglia Lombardi A,Costanzo R,Catalano G,Bianco AR,De Placido S

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:The objective of this phase III trial was to compare chemotherapy combined with bevacizumab versus chemotherapy alone in the treatment of patients with advanced colorectal cancer. METHODS:From September 2004 till September 2008, 222 treatment-naive patients were enrolled and divided into 2 arms: 114 arm A pa...

journal_title：Oncology

authors： Stathopoulos GP,Batziou C,Trafalis D,Koutantos J,Batzios S,Stathopoulos J,Legakis J,Armakolas A

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVES:MicroRNA (miR)-503 is downregulated in several cancers and plays a tumor-suppressive role in carcinogenesis. However, the miR-503 expression pattern, its clinical significance and its molecular mechanism in colorectal cancer (CRC) have not been investigated. METHODS:We analyzed miR-503 expression in normal ...

journal_title：Oncology

authors： Noguchi T,Toiyama Y,Kitajima T,Imaoka H,Hiro J,Saigusa S,Tanaka K,Inoue Y,Mohri Y,Toden S,Kusunoki M

更新日期：2016-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is characterized as a highly chemoresistant cancer with no effective systemic therapy. Despite surgical or locoregional therapies, prognosis remains poor because of high tumor recurrence or tumor progression, and currently there are no well-established effective adjuvant therapies. The m...

journal_title：Oncology

authors： Pang RW,Poon RT

更新日期：2007-01-01 00:00:00