Antigenic analysis of equine infectious anemia virus (EIAV) variants by using monoclonal antibodies: epitopes of glycoprotein gp90 of EIAV stimulate neutralizing antibodies.

abstract：:The synthesis of minus-strand RNA was studied in cell cultures infected with the heat-resistant strain of Sindbis virus and with temperature-sensitive (ts) belonging to complementation groups A, B, F, and G, all of which exhibited an RNA-negative (RNA-) phenotype when infection was initiated and maintained at 39 degre...

journal_title：Journal of virology

authors： Sawicki DL,Sawicki SG,Keränen S,Kääriäinen L

更新日期：1981-08-01 00:00:00

abstract：:Minute virus of canines (MVC) is a member of the genus Bocavirus in the family Parvoviridae. We have molecularly cloned and sequenced the 5'- and 3'-terminal palindromes of MVC. The MVC genome, 5,404 nucleotides (nt) in length, shared an identity of 52.6% and 52.1% with that of human bocavirus and bovine parvovirus, r...

journal_title：Journal of virology

authors： Sun Y,Chen AY,Cheng F,Guan W,Johnson FB,Qiu J

更新日期：2009-04-01 00:00:00

abstract：:We have used a replication-competent shuttle vector based on the genome of Rous sarcoma virus to characterize genomic rearrangements that occur during retrovirus replication. The strategy involved cloning circular DNA that was generated during an acute infection. While analyzing a class of retroviral DNA clones that a...

journal_title：Journal of virology

authors： Dunn MM,Olsen JC,Swanstrom R

更新日期：1992-10-01 00:00:00

abstract：:The oligosaccharide processing and secretion of hepatitis B surface antigen (HBsAg) was studied in Chinese hamster ovary cells stably transfected with the gene coding HBsAg. HBsAg was secreted from cells with a relatively long half time (ca. 5 h). This appeared to be a characteristic of HBsAg itself, since HBsAg-produ...

journal_title：Journal of virology

authors： Patzer EJ,Nakamura GR,Yaffe A

更新日期：1984-08-01 00:00:00

abstract：:This study reports the identification and initial characterization of the precursors, modified forms, and oligomers of bovine herpesvirus 1 (BHV-1) gI and gE proteins with polyvalent rabbit serum specific for gI or gE. Our experiments used the Colorado strain of BHV-1 and mutant viruses with insertions of the Escheric...

journal_title：Journal of virology

authors： Whitbeck JC,Knapp AC,Enquist LW,Lawrence WC,Bello LJ

更新日期：1996-11-01 00:00:00

abstract：:Vertebrates mount a strong innate immune response against viruses, largely by activating the interferon system. Double-stranded RNA (dsRNA), a common intermediate formed during the life cycle of many viruses, is a potent trigger of this response. In contrast, no general inducible antiviral defense mechanism has been r...

journal_title：Journal of virology

authors： Robalino J,Browdy CL,Prior S,Metz A,Parnell P,Gross P,Warr G

更新日期：2004-10-01 00:00:00

abstract：:Retroviral integrases associate during the early viral life cycle with preintegration complexes that catalyze the integration of reverse-transcribed viral cDNA into the host chromosomes. Several cellular and viral proteins have been reported to be incorporated in the preintegration complex. This study demonstrates tha...

journal_title：Journal of virology

authors： Inayoshi Y,Okino Y,Miyake K,Mizutani A,Yamamoto-Kishikawa J,Kinoshita Y,Morimoto Y,Imamura K,Morshed M,Kono K,Itoh T,Nishijima K,Iijima S

更新日期：2010-08-01 00:00:00

abstract：:Some strains of the protozoan parasite genus Leishmania are persistently infected with single-segmented double-stranded RNA viruses, which are termed LRV. The function of these cytoplasmic viruses is unknown. In order to address the question of whether LRV affects the parasite's phenotype, pairs of isogenic LRV(+)-LRV...

journal_title：Journal of virology

authors： Widmer G

更新日期：1995-07-01 00:00:00

abstract：:We have amplified by the polymerase chain reaction, cloned, and sequenced genomic segments of 118 human papillomavirus type 16 (HPV-16) isolates from 76 cervical biopsy, 14 cervical smear, 3 vulval biopsy, 2 penile biopsy, 2 anal biopsy, and 1 vaginal biopsy sample and two cell lines. The specimens were taken from pat...

journal_title：Journal of virology

authors： Chan SY,Ho L,Ong CK,Chow V,Drescher B,Dürst M,ter Meulen J,Villa L,Luande J,Mgaya HN

更新日期：1992-04-01 00:00:00

abstract：:A herpes simplex virus type 1 (HSV-1) strain, B3, was found to have a short duplication on the left junction between the unique sequence (US) and the inverted repeat sequence (RS) in the S component of the genome DNA. A short region of RS contiguous to the left US-RS junction was duplicated in B3. Based on the nucleot...

journal_title：Journal of virology

authors： Umene K

更新日期：1989-05-01 00:00:00

abstract：:As part of the continuing effort to develop an effective HIV vaccine, we generated a poxviral vaccine vector (previously described) designed to improve on the results of the RV144 phase III clinical trial. The construct, NYVAC-KC, is a replication-competent, attenuated recombinant of the vaccinia virus strain NYVAC. N...

journal_title：Journal of virology

authors： Kibler KV,Asbach B,Perdiguero B,García-Arriaza J,Yates NL,Parks R,Stanfield-Oakley S,Ferrari G,Montefiori DC,Tomaras GD,Roederer M,Foulds KE,Forthal DN,Seaman MS,Self S,Gottardo R,Phogat S,Tartaglia J,Barnett S,Cris

更新日期：2019-01-17 00:00:00

abstract：:Since the number of human cases of infection with avian H5N1 influenza viruses is ever increasing, a pandemic outbreak caused by these viruses is feared. Therefore, in addition to virus-specific antibodies, there is considerable interest in immune correlates of protection against these viruses, which could be a target...

journal_title：Journal of virology

authors： Kreijtz JH,de Mutsert G,van Baalen CA,Fouchier RA,Osterhaus AD,Rimmelzwaan GF

更新日期：2008-06-01 00:00:00

abstract：:The feline homolog of the alpha-chemokine receptor CXCR4 has recently been shown to support cell-cell fusion mediated by CXCR4-dependent strains of human immunodeficiency virus (HIV) and strains of feline immunodeficiency virus (FIV) that have been selected for growth in the Crandell feline kidney (CrFK) cell line. In...

journal_title：Journal of virology

authors： Willett BJ,Adema K,Heveker N,Brelot A,Picard L,Alizon M,Turner JD,Hoxie JA,Peiper S,Neil JC,Hosie MJ

更新日期：1998-08-01 00:00:00

abstract：:JC virus (JCV), along with other members of the polyomavirus family, encodes a class of highly conserved proteins, T antigens, that are capable of inducing aneuploidy in cultured cells. We have previously isolated T-antigen DNA variants of JCV from both colon cancer tissues and the corresponding nonneoplastic gastroin...

journal_title：Journal of virology

authors： Ricciardiello L,Chang DK,Laghi L,Goel A,Chang CL,Boland CR

更新日期：2001-02-01 00:00:00

abstract：:Infection of cells with enveloped viruses is accomplished through membrane fusion. The binding and fusion processes are mediated by the spike proteins in the envelope of the virus particle and usually involve a series of conformational changes in these proteins. We have studied the low-pH-mediated fusion process of th...

journal_title：Journal of virology

authors： Wahlberg JM,Bron R,Wilschut J,Garoff H

更新日期：1992-12-01 00:00:00

abstract：:Vesicular stomatitis virus (VSV) has been shown in laboratory studies to be effective against a variety of tumors, including malignant brain tumors. However, attenuation of VSV may be necessary to balance the potential toxicity toward normal cells, particularly when targeting brain tumors. Here we compared 10 recombin...

journal_title：Journal of virology

authors： Wollmann G,Rogulin V,Simon I,Rose JK,van den Pol AN

更新日期：2010-02-01 00:00:00

abstract：:Rhesus cytomegalovirus (RhCMV) infection of macaques exhibits strong similarities to human CMV (HCMV) persistence and pathogenesis. The immunogenicity of DNA vaccines encoding three RhCMV proteins (a truncated version of glycoprotein B lacking the transmembrane region and endodomain [gBDeltaTM], phosphoprotein 65-2 [p...

journal_title：Journal of virology

authors： Yue Y,Kaur A,Eberhardt MK,Kassis N,Zhou SS,Tarantal AF,Barry PA

更新日期：2007-02-01 00:00:00

abstract：:To assess the RNA helicase activity of hepatitis C virus (HCV) nonstructural protein 3 (NS3), a polypeptide encompassing amino acids 1175 to 1657, which cover only the putative helicase domain, was expressed in Escherichia coli by a pET expression vector. The protein was purified to near homogeneity and assayed for RN...

journal_title：Journal of virology

authors： Tai CL,Chi WK,Chen DS,Hwang LH

更新日期：1996-12-01 00:00:00

abstract：:During herpes simplex virus (HSV) latency, most viral genes are silenced, with the exception of one region of the genome encoding the latency-associated transcript (LAT). This long noncoding RNA was originally described as having a role in enhancing HSV-1 reactivation. However, subsequent evidence showing that the LAT...

journal_title：Journal of virology

authors： Watson ZL,Washington SD,Phelan DM,Lewin AS,Tuli SS,Schultz GS,Neumann DM,Bloom DC

更新日期：2018-07-31 00:00:00

abstract：:The Roseobacter clade has been recognized as one of the abundant bacterial lineages in marine environments, which makes the characterization of bacteriophages infecting members of the clade important. Here we report the complete genome sequence of bacteriophage P12053L, which infects Celeribacter sp. strain IMCC12053,...

journal_title：Journal of virology

authors： Kang I,Jang H,Oh HM,Cho JC

更新日期：2012-08-01 00:00:00

abstract：:Understanding how viral components collaborate to convert the human immunodeficiency virus type 1 genome from single-stranded RNA into double-stranded DNA is critical to the understanding of viral replication. Not only must the correct reactions be carried out, but unwanted side reactions must be avoided. After minus-...

journal_title：Journal of virology

authors： Driscoll MD,Hughes SH

更新日期：2000-10-01 00:00:00

abstract：:Murine gammaherpesvirus 68 (MHV68) is a gammaherpesvirus that was first isolated from murid rodents. MHV68 establishes a latent infection in the spleen and other lymphoid organs. Several gammaherpesviruses, including herpesvirus saimiri, human herpesvirus 8, and MHV68, encode proteins with extensive homology to the D-...

journal_title：Journal of virology

authors： Hoge AT,Hendrickson SB,Burns WH

更新日期：2000-08-01 00:00:00

abstract：:Epstein-Barr virus (EBV) is a herpesvirus commonly associated with several malignancies, particularly in immunocompromised hosts. As a strategy for stimulating immunity against EBV for the treatment of EBV-associated tumors, we have genetically engineered dendritic cells (DC) to express EBV antigens, such as latent me...

journal_title：Journal of virology

authors： Ranieri E,Herr W,Gambotto A,Olson W,Rowe D,Robbins PD,Kierstead LS,Watkins SC,Gesualdo L,Storkus WJ

更新日期：1999-12-01 00:00:00

abstract：:A deletion mutant of severe acute respiratory syndrome coronavirus (SARS-CoV) has been engineered by deleting the structural E gene in an infectious cDNA clone that was constructed as a bacterial artificial chromosome (BAC). The recombinant virus lacking the E gene (rSARS-CoV-DeltaE) was rescued in Vero E6 cells. The ...

journal_title：Journal of virology

authors： DeDiego ML,Alvarez E,Almazán F,Rejas MT,Lamirande E,Roberts A,Shieh WJ,Zaki SR,Subbarao K,Enjuanes L

更新日期：2007-02-01 00:00:00

abstract：:RNA was extracted from the Burkitt lymphoma-derived cell line Raji and from Burkitt lymphoma tumor biopsies, isotope labeled in vitro by iodination with 125I, and hybridized to electrophoretically separated restriction endonuclease fragments of Epstein-Barr virus DNA on nitrocellulose membranes. The results indicated ...

journal_title：Journal of virology

authors： Rymo L

更新日期：1979-10-01 00:00:00

abstract：:Cucumber mosaic virus (CMV) is a tripartite RNA virus that can support the replication of satellite RNAs, small molecular parasites of the virus. Satellite RNAs can have a dramatic effect on the helper virus and the host plant in a manner specific to the helper, satellite, and host. Previously, we showed that the Sny-...

journal_title：Journal of virology

authors： Roossinck MJ,Kaplan I,Palukaitis P

更新日期：1997-01-01 00:00:00

abstract：:The state of intracellular viral DNA in cells infected with channel catfish virus has been studied by the Hirt selective extraction procedure and by restriction endonuclease digestion. The sedimentation properties and restriction patterns of viral DNA in the Hirt supernatant fraction indicate that the majority, if not...

journal_title：Journal of virology

authors： Cebrian J,Bucchini D,Sheldrick P

更新日期：1983-05-01 00:00:00

abstract：:We have examined the transcriptional utilization of the human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR) under differentiating conditions by using the embryonal carcinoma cell line NTERA-2. NTERA-2 cells undergo two distinct pathways of terminal differentiation, to a neuronal phenotype in respons...

journal_title：Journal of virology

authors： Zeichner SL,Hirka G,Andrews PW,Alwine JC

更新日期：1992-04-01 00:00:00

abstract：:The nef genes of the human immunodeficiency viruses type 1 and 2 (HIV-1 and HIV-2) and the related simian immunodeficiency viruses (SIVs) encode a protein (Nef) whose role in virus replication and cytopathicity remains uncertain. As an attempt to elucidate the function of nef, we characterized the nucleotide and corre...

journal_title：Journal of virology

authors： Shugars DC,Smith MS,Glueck DH,Nantermet PV,Seillier-Moiseiwitsch F,Swanstrom R

更新日期：1993-08-01 00:00:00

abstract：:Live attenuated human immunodeficiency virus type 1 (HIV-1) vaccines are considered unsafe because faster-replicating pathogenic virus variants may evolve after vaccination. We previously presented a conditional-live HIV-1 variant of which replication can be switched off as an alternative vaccination strategy. To impr...

journal_title：Journal of virology

authors： Das AT,Baldwin CE,Vink M,Berkhout B

更新日期：2005-03-01 00:00:00