Complete genome sequence of Celeribacter bacteriophage P12053L.

abstract：UNLABELLED:Bean pod mottle virus (BPMV) is a bipartite, positive-sense (+) RNA plant virus in the Secoviridae family. Its RNA1 encodes proteins required for genome replication, whereas RNA2 primarily encodes proteins needed for virion assembly and cell-to-cell movement. However, the function of a 58-kDa protein (P58) e...

journal_title：Journal of virology

authors： Lin J,Guo J,Finer J,Dorrance AE,Redinbaugh MG,Qu F

更新日期：2014-03-01 00:00:00

abstract：:The current studies demonstrate complex and seemingly contradictory effects by gamma interferon (IFN-gamma) on Friend virus (FV) infection. Both temporal and tissue-specific effects were observed. During the first week of infection, IFN-gamma-deficiency caused increased levels of FV infection in multiple tissues. Surp...

journal_title：Journal of virology

authors： Stromnes IM,Dittmer U,Schumacher TN,Schepers K,Messer RJ,Evans LH,Peterson KE,Race B,Hasenkrug KJ

更新日期：2002-03-01 00:00:00

abstract：:An adeno-associated virus (AAV) genome with a Lys-to-His (K340H) mutation in the consensus nucleotide triphosphate binding site of the rep gene has a dominant-negative DNA replication phenotype in vivo. We expressed both wild-type (Rep78) and mutant (Rep78NTP) proteins in two helper-free expression systems consisting ...

journal_title：Journal of virology

authors： Owens RA,Carter BJ

更新日期：1992-02-01 00:00:00

abstract：:Hepatitis C virus (HCV) enters cells via a pH- and clathrin-dependent endocytic pathway. Scavenger receptor BI (SR-BI) and CD81 are important entry factors for HCV internalization into target cells. The SR-BI gene gives rise to at least two mRNA splice variants, SR-BI and SR-BII, which differ in their C termini. SR-BI...

journal_title：Journal of virology

authors： Grove J,Huby T,Stamataki Z,Vanwolleghem T,Meuleman P,Farquhar M,Schwarz A,Moreau M,Owen JS,Leroux-Roels G,Balfe P,McKeating JA

更新日期：2007-04-01 00:00:00

abstract：UNLABELLED:Gammaherpesviruses establish persistent, systemic infections and cause cancers. Murid herpesvirus 4 (MuHV-4) provides a unique window into the early events of host colonization. It spreads via lymph nodes. While dendritic cells (DC) pass MuHV-4 to lymph node B cells, subcapsular sinus macrophages (SSM), whic...

journal_title：Journal of virology

authors： Lawler C,Tan CS,Simas JP,Stevenson PG

更新日期：2016-09-29 00:00:00

abstract：:A study of virus-specific protein synthesis in infectious pancreatic necrosis virus-infected RTG-2 cells was undertaken to find a relationship between the coding capacity of virus genome (two segments of double-stranded RNA of 2.5 X10(6) and 2.3 X 10(6) molecular weight) and the sizes and relative amounts of polypepti...

journal_title：Journal of virology

authors： Dobos P

更新日期：1977-01-01 00:00:00

abstract：:Upon stimulation with alpha/beta interferon, rat cells synthesize three Mx proteins. Sequence analysis of corresponding cDNAs reveals that these three proteins are derived from three distinct genes. One of the rat cDNAs is termed Mx1 because it is most closely related to the mouse Mx1 cDNA and because it codes for a n...

journal_title：Journal of virology

authors： Meier E,Kunz G,Haller O,Arnheiter H

更新日期：1990-12-01 00:00:00

abstract：UNLABELLED:As a herpesvirus, Epstein-Barr virus (EBV) establishes a latent infection that can periodically undergo reactivation, resulting in lytic replication and the production of new infectious virus. Latent membrane protein-1 (LMP1), the principal viral oncoprotein, is a latency-associated protein implicated in reg...

journal_title：Journal of virology

authors： Bentz GL,Moss CR 2nd,Whitehurst CB,Moody CA,Pagano JS

更新日期：2015-08-01 00:00:00

abstract：:Canine distemper virus (CDV) uses signaling lymphocyte activation molecule (SLAM), expressed on immune cells, as a receptor. However, epithelial and neural cells are also affected by CDV in vivo. Wild-type CDV strains showed efficient replication with syncytia in Vero cells expressing dog nectin4, and the infection wa...

journal_title：Journal of virology

authors： Pratakpiriya W,Seki F,Otsuki N,Sakai K,Fukuhara H,Katamoto H,Hirai T,Maenaka K,Techangamsuwan S,Lan NT,Takeda M,Yamaguchi R

更新日期：2012-09-01 00:00:00

abstract：:CD4C/HIV(nef) transgenic (Tg) mice express Nef in CD4+ T cells and in the cells of the macrophage/monocyte/dendritic lineage, and they develop an AIDS-like disease similar to human AIDS. In these mice, Nef is constitutively expressed throughout life. To rule out the contribution of any developmental defects caused by ...

journal_title：Journal of virology

authors： Rahim MM,Chrobak P,Hu C,Hanna Z,Jolicoeur P

更新日期：2009-11-01 00:00:00

abstract：:Preferential integration into transcriptionally active regions of genomes has been observed for retroviral vectors based on gamma-retroviruses and lentiviruses. However, differences in the integration site preferences were detected, which might be explained by differences in viral components of the preintegration comp...

journal_title：Journal of virology

authors： Monse H,Laufs S,Kuate S,Zeller WJ,Fruehauf S,Uberla K

更新日期：2006-08-01 00:00:00

abstract：:Hepatitis A virus (HAV) is an enterically transmitted virus that replicates predominantly in hepatocytes within the liver before excretion via bile through feces. Hepatocytes are polarized epithelial cells, and it has been assumed that the virus load in bile results from direct export of HAV via the apical domain of p...

journal_title：Journal of virology

authors： Snooks MJ,Bhat P,Mackenzie J,Counihan NA,Vaughan N,Anderson DA

更新日期：2008-09-01 00:00:00

abstract：:Human papillomavirus type 11 (HPV-11) and HPV-16 contain an E5 gene that can induce c-fos gene expression in mouse fibroblasts. This study investigated the human c-fos promoter characteristics by mapping the c-fos promoter sequence with several deletion and point mutants that confer responsiveness to E5 of HPV-11 or H...

journal_title：Journal of virology

authors： Chen SL,Lin YK,Li LY,Tsao YP,Lo HY,Wang WB,Tsai TC

更新日期：1996-12-01 00:00:00

abstract：UNLABELLED:HIV-1 Vpu decreases the exposure of epitopes within the viral envelope glycoprotein (Env) on the surface of infected cells by downregulating both BST2 and CD4. To test the hypothesis that inhibiting Vpu activity would increase the exposure of these epitopes and sensitize infected cells to antibody-dependent ...

journal_title：Journal of virology

authors： Tokarev A,Stoneham C,Lewinski MK,Mukim A,Deshmukh S,Vollbrecht T,Spina CA,Guatelli J

更新日期：2015-12-16 00:00:00

abstract：:The identification of several simian immunodeficiency virus mac251 (SIV(mac251)) cytotoxic T-lymphocyte epitopes recognized by CD8(+) T cells of infected rhesus macaques carrying the Mamu-A*01 molecule and the use of peptide-major histocompatibility complex tetrameric complexes enable the study of the frequency, bread...

journal_title：Journal of virology

authors： Hel Z,Nacsa J,Kelsall B,Tsai WP,Letvin N,Parks RW,Tryniszewska E,Picker L,Lewis MG,Edghill-Smith Y,Moniuszko M,Pal R,Stevceva L,Altman JD,Allen TM,Watkins D,Torres JV,Berzofsky JA,Belyakov IM,Strober W,Franchini G

更新日期：2001-12-01 00:00:00

abstract：:The hepatitis C virus (HCV) core protein is known to be a multifunctional protein, besides being a component of viral nucleocapsids. Previously, we have shown that the core protein binds to the cytoplasmic domain of lymphotoxin beta receptor, which is a member of tumor necrosis factor receptor (TNFR) family. In this s...

journal_title：Journal of virology

authors： Zhu N,Khoshnan A,Schneider R,Matsumoto M,Dennert G,Ware C,Lai MM

更新日期：1998-05-01 00:00:00

abstract：:The Gag proteins of retroviruses are the only viral products required for the release of membrane-enclosed particles by budding from the host cell. Particles released when these proteins are expressed alone are identical to authentic virions in their rates of budding, proteolytic processing, and core morphology, as we...

journal_title：Journal of virology

authors： Krishna NK,Campbell S,Vogt VM,Wills JW

更新日期：1998-01-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) primarily infect activated CD4(+) T cells but can infect macrophages. Surprisingly, ex vivo tetramer-sorted SIV-specific CD8(+) T cells that eliminated and suppressed viral replication in SIV-infected CD4(+) T cells failed to do so in SIV-infec...

journal_title：Journal of virology

authors： Vojnov L,Martins MA,Bean AT,Veloso de Santana MG,Sacha JB,Wilson NA,Bonaldo MC,Galler R,Stevenson M,Watkins DI

更新日期：2012-04-01 00:00:00

abstract：:Papillomaviruses normally replicate in stratified squamous epithelial tissues of their mammalian hosts, in which the viral genome is found as a nuclear plasmid. Two viral proteins, E1, a helicase, and E2, a transcriptional activator and plasmid maintenance factor, are known to contribute to the episomal replication of...

journal_title：Journal of virology

authors： Angeletti PC,Kim K,Fernandes FJ,Lambert PF

更新日期：2002-04-01 00:00:00

abstract：:Maintenance of Kaposi's sarcoma-associated herpesvirus (KSHV) latent infection depends on the viral episomes in the nucleus being distributed to daughter cells following cell division. The latency-associated nuclear antigen (LANA) is constitutively expressed in all KSHV-infected cells. LANA binds sequences in the term...

journal_title：Journal of virology

authors： Krithivas A,Fujimuro M,Weidner M,Young DB,Hayward SD

更新日期：2002-11-01 00:00:00

abstract：:The transforming proteins of the small DNA tumor viruses, simian virus 40 (SV40), adenovirus, and human papillomavirus (HPV) target a number of identical cellular regulators whose functional abrogation is required for transformation. However, while both adenovirus E1A and SV40 large T transforming properties also depe...

journal_title：Journal of virology

authors： Zimmermann H,Degenkolbe R,Bernard HU,O'Connor MJ

更新日期：1999-08-01 00:00:00

abstract：:The large scale of the Ebola virus disease (EVD) outbreak in West Africa in 2013-2016 raised the question whether the host cell interactions of the responsible Ebola virus (EBOV) strain differed from those of other ebolaviruses. We previously reported that the glycoprotein (GP) of the virus circulating in West Africa ...

journal_title：Journal of virology

authors： Hoffmann M,Crone L,Dietzel E,Paijo J,González-Hernández M,Nehlmeier I,Kalinke U,Becker S,Pöhlmann S

更新日期：2017-04-13 00:00:00

abstract：:The investigation of papillomavirus chromatin has been hampered by the unavailability of a tissue culture system for vegetative growth of these viruses. We have used, therefore, bovine papillomavirus type 1-transformed hamster embryo fibroblasts containing 200 to 250 episomal genome equivalents per cell as a source of...

journal_title：Journal of virology

authors： Rösl F,Waldeck W,Sauer G

更新日期：1983-05-01 00:00:00

abstract：:Q beta phage RNAs with inactivating insertion (8-base) or deletion (17-base) mutations within their replicase genes were prepared from modified Q beta cDNAs and transfected into Escherichia coli spheroplasts containing Q beta replicase provided in trans by a resident plasmid. Replicase-defective (Rep-) Q beta phage pr...

journal_title：Journal of virology

authors： Palasingam K,Shaklee PN

更新日期：1992-04-01 00:00:00

abstract：:In vitro replication of coxsackievirus B3 (CVB3) in cells of the immune system derived from uninfected adolescent A/J and C57BL/6J mice and replication of CVB3 in and association with immune cells from spleens of infected animals in vivo were assessed. Nonstimulated or mitogen-stimulated spleen cells were minimally pe...

journal_title：Journal of virology

authors： Anderson DR,Wilson JE,Carthy CM,Yang D,Kandolf R,McManus BM

更新日期：1996-07-01 00:00:00

abstract：:In some type C retroviruses, translation of the pol gene appears to require translational suppression of the proximal gag amber codon. To identify the region of the viral nucleic acid responsible for synthesis of the pol gene products, a 300-base-pair DNA fragment containing the stop codon from a type C murine virus (...

journal_title：Journal of virology

authors： Panganiban AT

更新日期：1988-10-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) infects alveolar macrophages (AMϕ), causing dysregulated alpha interferon (IFN-α) and tumor necrosis factor alpha (TNF-α) production through a mechanism(s) yet to be resolved. Here, we show that AMϕ infected with PRRSV secreted a reduced quantity of IFN-α fol...

journal_title：Journal of virology

authors： Chen WY,Schniztlein WM,Calzada-Nova G,Zuckermann FA

更新日期：2018-01-02 00:00:00

abstract：:The transmembrane fusion (F) glycoprotein of measles virus is an important target antigen of human HLA class I- and class II-restricted cytotoxic T lymphocytes (CTL). Genetically engineered F proteins and nested sets of synthetic peptides spanning the F protein were used to determine sequences of F recognized by a num...

journal_title：Journal of virology

authors： van Binnendijk RS,Versteeg-van Oosten JP,Poelen MC,Brugghe HF,Hoogerhout P,Osterhaus AD,Uytdehaag FG

更新日期：1993-04-01 00:00:00

abstract：:We have examined the transcriptional utilization of the human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR) under differentiating conditions by using the embryonal carcinoma cell line NTERA-2. NTERA-2 cells undergo two distinct pathways of terminal differentiation, to a neuronal phenotype in respons...

journal_title：Journal of virology

authors： Zeichner SL,Hirka G,Andrews PW,Alwine JC

更新日期：1992-04-01 00:00:00

abstract：:V3-glycan-targeting broadly neutralizing antibodies (bNAbs) are a focus of HIV-1 vaccine development. Understanding the viral dynamics that stimulate the development of these antibodies can provide insights for immunogen design. We used a deep-sequencing approach, together with neutralization phenotyping, to investiga...

journal_title：Journal of virology

authors： Anthony C,York T,Bekker V,Matten D,Selhorst P,Ferreria RC,Garrett NJ,Karim SSA,Morris L,Wood NT,Moore PL,Williamson C

更新日期：2017-08-24 00:00:00