Transcription factor YY1 interacts with retroviral integrases and facilitates integration of moloney murine leukemia virus cDNA into the host chromosomes.

abstract：:The chimpanzee monoclonal antibody (MAb) 5H2 is specific for dengue virus type 4 (DENV-4) and neutralizes the virus at a high titer in vitro. The epitope detected by the antibody was mapped by sequencing neutralization escape variants of the virus. One variant contained a Lys174-Glu substitution and another contained ...

journal_title：Journal of virology

authors： Lai CJ,Goncalvez AP,Men R,Wernly C,Donau O,Engle RE,Purcell RH

更新日期：2007-12-01 00:00:00

abstract：:A virus (M-7) isolated from baboon placental tissue demonstrates many similarities to endogenous feline virus RD-114. Immunodiffusion analysis shows a group-specific antigen (gs-1) line of identity between M-7 and RD-114. Anti-RD-114 DNA polymerase IgG inhibits M-7 polymerase by 57% compared to 97% for RD-114. M-7 vir...

journal_title：Journal of virology

authors： Hellman A,Peebles PT,Strickland JE,Fowler AK,Kalter SS,Oroszlan KS,Gilden RV

更新日期：1974-07-01 00:00:00

abstract：:Measles virus (MV) fusion requires the participation of both the fusion (F) and hemagglutinin (H) glycoproteins. The canine distemper virus fusion protein (CDVF) cannot substitute for the measles virus fusion protein (MVF) in this process. Introduction of restriction enzyme sites into the cDNAs of CDVF and MVF by site...

journal_title：Journal of virology

authors： Wild TF,Fayolle J,Beauverger P,Buckland R

更新日期：1994-11-01 00:00:00

abstract：:Viruses can induce progressive neurologic disorders associated with diverse pathological manifestations, and therefore, viral infection of the brain can impair differentiated neural functions, depending on the initial viral tropism. We have previously reported that canine distemper virus (CDV) targets certain mouse br...

journal_title：Journal of virology

authors： Bernard A,Cohen R,Khuth ST,Vedrine B,Verlaeten O,Akaoka H,Giraudon P,Belin MF

更新日期：1999-09-01 00:00:00

abstract：:We sought proof of principle that one of the safest human vaccines, measles virus Edmonston B (MV-Edm), can be genetically modified to allow entry via cell surface molecules other than its receptor CD46. Hybrid proteins consisting of the epidermal growth factor (EGF) or the insulin-like growth factor 1 (IGF1) linked t...

journal_title：Journal of virology

authors： Schneider U,Bullough F,Vongpunsawad S,Russell SJ,Cattaneo R

更新日期：2000-11-01 00:00:00

abstract：:Misfolded alpha-synuclein (αS) may exhibit a number of characteristics similar to those of the prion protein, including the apparent ability to spread along neuroanatomical connections. The demonstration for this mechanism of spread is largely based on the intracerebral injections of preaggregated αS seeds in mice, in...

journal_title：Journal of virology

authors： Ayers JI,Riffe CJ,Sorrentino ZA,Diamond J,Fagerli E,Brooks M,Galaleldeen A,Hart PJ,Giasson BI

更新日期：2018-08-29 00:00:00

abstract：:Splicing of human immunodeficiency virus type 1 (HIV-1) exon 6D is regulated by the presence of a complex splicing regulatory element (SRE) sequence that interacts with the splicing factors hnRNP H and SC35. In this work, we show that, in the context of the wild-type viral sequence, hnRNP H acts as a repressor of exon...

journal_title：Journal of virology

authors： Jablonski JA,Buratti E,Stuani C,Caputi M

更新日期：2008-08-01 00:00:00

abstract：:An mRNA-ribonucleoprotein particle (mRNP) was found in vesicular stomatitis virus (VSV)-infected Chinese hamster ovary cells. The particle was present 3 and 4.5 h after infection but was barely discernible at 2 h. The mRNP (buoyant density, 1.56 g/cm3), which cosedimented with viral nucleocapsid in a sucrose density g...

journal_title：Journal of virology

authors： Rosen CA,Ennis HL,Cohen PS

更新日期：1982-12-01 00:00:00

abstract：:The key role of the mitochondria in the regulation of cellular Ca2+ led to a study of mitochondrial Ca2+ uptake during the infection of chicken embryo cells with Semliki Forest virus. Mitochondrial Ca2+ uptake was stimulated during the first 5 h of infection but declined later in infection. The early stimulation sugge...

journal_title：Journal of virology

authors： Peterhans E,Haenggeli E,Wild P,Wyler R

更新日期：1979-01-01 00:00:00

abstract：:Complementary DNA clones encoding the murine homolog (mCAR) of the human coxsackievirus and adenovirus receptor (CAR) were isolated. Nonpermissive CHO cells transfected with mCAR cDNA became susceptible to infection by coxsackieviruses B3 and B4 and showed increased susceptibility to adenovirus-mediated gene transfer....

journal_title：Journal of virology

authors： Bergelson JM,Krithivas A,Celi L,Droguett G,Horwitz MS,Wickham T,Crowell RL,Finberg RW

更新日期：1998-01-01 00:00:00

abstract：UNLABELLED:Oncolytic viruses (OVs) are attractive avenues of cancer therapy due to the absence of toxic side effects often seen with current treatment modalities. Bovine herpesvirus 1 (BHV-1) is a species-specific virus that does not induce cytotoxicity in normal primary human cells but can infect and kill various huma...

journal_title：Journal of virology

authors： Cuddington BP,Mossman KL

更新日期：2014-06-01 00:00:00

abstract：:The interaction of the mouse hepatitis virus (MHV) nucleocapsid protein (N) and viral RNA was examined. Monoclonal antibody specific for N protein coimmunoprecipitated MHV genomic RNA as well as all six MHV subgenomic mRNAs found in MHV-infected cells. In contrast, monoclonal antibodies to the MHV E2 or E1 envelope gl...

journal_title：Journal of virology

authors： Baric RS,Nelson GW,Fleming JO,Deans RJ,Keck JG,Casteel N,Stohlman SA

更新日期：1988-11-01 00:00:00

abstract：:Highly pathogenic H5N1 influenza A virus remains a substantial threat to public health. To understand the molecular basis and host mechanism for the high virulence of H5N1 viruses in mammals, we compared two H5N1 isolates which have similar genetic backgrounds but greatly differ in their virulence in mice. A/Chicken/J...

journal_title：Journal of virology

authors： Hu J,Hu Z,Song Q,Gu M,Liu X,Wang X,Hu S,Chen C,Liu H,Liu W,Chen S,Peng D,Liu X

更新日期：2013-03-01 00:00:00

abstract：:Human noroviruses are the most common nonbacterial cause of gastroenteritis outbreaks, with new variants and genotypes frequently emerging. The origin of these new viruses is unknown; however, animals have been proposed as a potential source, as human noroviruses have been detected in animal species. Here, we investig...

journal_title：Journal of virology

authors： Villabruna N,Schapendonk CME,Aron GI,Koopmans MPG,de Graaf M

更新日期：2021-01-13 00:00:00

abstract：:Baculoviruses, although they infect insects in nature, can transduce a wide variety of mammalian cells and are therefore promising gene therapy vectors. However, baculovirus transduction into many mammalian cells is very inefficient, and the limiting stages and factors remain unknown. An important finding is that a sh...

journal_title：Journal of virology

authors： Hu L,Li Y,Ning YJ,Deng F,Vlak JM,Hu Z,Wang H,Wang M

更新日期：2019-07-17 00:00:00

abstract：:Lentiviruses have long been considered host-specific pathogens, but several recent observations demonstrated their capacity to conquer new hosts from different species, genera, and families. From these cross-species infections emerged new animal and human infectious diseases. The successful colonization and adaptation...

journal_title：Journal of virology

authors： Morin T,Guiguen F,Bouzar BA,Villet S,Greenland T,Grezel D,Gounel F,Gallay K,Garnier C,Durand J,Alogninouwa T,Mselli-Lakhal L,Mornex JF,Chebloune Y

更新日期：2003-06-01 00:00:00

abstract：:Animals that naturally acquire the prion diseases have a well-developed olfactory sense that they utilize for a variety of basic behaviors. To assess the potential for the nasal cavity to serve as a point of entry for prion diseases, a small amount of prion-infected brain homogenate was placed inferior to the nostrils...

journal_title：Journal of virology

authors： Kincaid AE,Bartz JC

更新日期：2007-05-01 00:00:00

abstract：:The N termini of the capsid proteins VP1 and VP2 of adeno-associated virus (AAV) play important roles in subcellular steps of infection and contain motifs that are highly homologous to a phospholipase A(2) (PLA(2)) domain and nuclear localization signals (NLSs). To more clearly understand how virion components influen...

journal_title：Journal of virology

authors： Johnson JS,Li C,DiPrimio N,Weinberg MS,McCown TJ,Samulski RJ

更新日期：2010-09-01 00:00:00

abstract：:The locations and functions of DNA sequences involved in transcription of the gene encoding herpes simplex virus type 1 immediate early (IE) mRNAs 4 and 5 were analyzed by use of a transient-expression assay. The region upstream of the genes encoding IE mRNAs 4 and 5 was fused to the thymidine kinase gene coding seque...

journal_title：Journal of virology

authors： Preston CM,Cordingley MG,Stow ND

更新日期：1984-06-01 00:00:00

abstract：:Despite reports of viral genetic defects in persons who control human immunodeficiency virus type 1 (HIV-1) in the absence of antiviral therapy, the extent to which such defects contribute to the long-term containment of viremia is not known. Most previous studies examining for such defects have involved small numbers...

journal_title：Journal of virology

authors： Miura T,Brockman MA,Brumme CJ,Brumme ZL,Carlson JM,Pereyra F,Trocha A,Addo MM,Block BL,Rothchild AC,Baker BM,Flynn T,Schneidewind A,Li B,Wang YE,Heckerman D,Allen TM,Walker BD

更新日期：2008-09-01 00:00:00

abstract：UNLABELLED:Flaviviruses pose a significant threat to both animals and humans. Recently, a novel flavivirus, duck Tembusu virus (DTMUV), was identified to be the causative agent of a serious duck viral disease in Asia. Its rapid spread, expanding host range, and uncertain transmission routes have raised substantial conc...

journal_title：Journal of virology

authors： Wang HJ,Li XF,Liu L,Xu YP,Ye Q,Deng YQ,Huang XY,Zhao H,Qin ED,Shi PY,Gao GF,Qin CF

更新日期：2016-06-24 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) infection of CD4-positive lymphocytes is accompanied by acute cytopathic effects, i.e., syncytium formation and single-cell lysis. Syncytium formation involves cell-cell fusion mediated by viral envelope glycoproteins on the surface of infected cells and by CD4 glycoproteins...

journal_title：Journal of virology

authors： Cao J,Park IW,Cooper A,Sodroski J

更新日期：1996-03-01 00:00:00

abstract：:Ground squirrel hepatitis virus (GSHV) is a small DNA virus, structurally and antigenically related to the human hepatitis B virus, which occurs naturally among certain wild populations of ground squirrels (P. L. Marion et al., Proc. Natl. Acad. Sci. U.S.A. 77:2941-2945, 1980). Serum from naturally infected animals wa...

journal_title：Journal of virology

authors： Ganem D,Weiser B,Barchuk A,Brown RJ,Varmus HE

更新日期：1982-10-01 00:00:00

abstract：:Human immunodeficiency virus clade C (HIV-C) accounts for >56% of all HIV infections worldwide. To investigate vaccine safety and efficacy in nonhuman primates, a pathogenic, R5-tropic, neutralization-sensitive simian-human immunodeficiency virus (SHIV) carrying HIV-C env would be desirable. We have constructed SHIV-2...

journal_title：Journal of virology

authors： Siddappa NB,Song R,Kramer VG,Chenine AL,Velu V,Ong H,Rasmussen RA,Grisson RD,Wood C,Zhang H,Kankasa C,Amara RR,Else JG,Novembre FJ,Montefiori DC,Ruprecht RM

更新日期：2009-02-01 00:00:00

abstract：:To determine whether the tripartite leader is required for efficient translation in adenovirus-infected cells at late times of infection, we constructed recombinant adenoviruses containing the influenza virus nucleocapsid protein (NP) gene expressed under the control of the adenovirus major late promoter (MLP). We cho...

journal_title：Journal of virology

authors： Alonso-Caplen FV,Katze MG,Krug RM

更新日期：1988-05-01 00:00:00

abstract：:Simian immunodeficiency virus (SIV) infection of rhesus macaques has become an important surrogate model for evaluating HIV vaccine strategies. The extreme resistance to neutralizing antibody (NAb) of many commonly used strains, such as SIVmac251/239 and SIVsmE543-3, limits their potential relevance for evaluating the...

journal_title：Journal of virology

authors： Wu F,Ourmanov I,Kuwata T,Goeken R,Brown CR,Buckler-White A,Iyengar R,Plishka R,Aoki ST,Hirsch VM

更新日期：2012-08-01 00:00:00

abstract：:Proteomic identification of human papillomavirus type 16 (HPV16) E6-interacting proteins revealed several proteins involved in ubiquitin-mediated proteolysis. In addition to the well-characterized E6AP ubiquitin-protein ligase, a second HECT domain protein (HERC2) and a deubiquitylating enzyme (USP15) were identified ...

journal_title：Journal of virology

authors： Vos RM,Altreuter J,White EA,Howley PM

更新日期：2009-09-01 00:00:00

abstract：:Hepatitis delta antigen (HDAg) is the only known protein of hepatitis delta virus and was previously shown to localize in the nucleoplasm of infected liver cells. In this study, nuclear localization signals of HDAg were defined by expressing various domains of the antigen in both hepatic and nonhepatic cells as beta-g...

journal_title：Journal of virology

authors： Chang MF,Chang SC,Chang CI,Wu K,Kang HY

更新日期：1992-10-01 00:00:00

abstract：:Protective immunity to rotavirus (RV) is primarily mediated by antibodies produced by RV-specific memory B cells (RV-mBc). Of note, most of these cells express IgM, but the function of this subset is poorly understood. Here, using limiting dilution assays of highly sort-purified human IgM(+) mBc, we found that 62% and...

journal_title：Journal of virology

authors： Narváez CF,Feng N,Vásquez C,Sen A,Angel J,Greenberg HB,Franco MA

更新日期：2012-10-01 00:00:00

abstract：:Rhesus monkey rhadinovirus (RRV), a simian gamma-2 herpesvirus closely related to the Kaposi sarcoma-associated herpesvirus, replicates lytically in cultured rhesus monkey fibroblasts and establishes persistence in B cells. Overlapping cosmid clones were generated that encompass the entire 130-kilobase-pair genome of ...

journal_title：Journal of virology

authors： Bilello JP,Morgan JS,Damania B,Lang SM,Desrosiers RC

更新日期：2006-02-01 00:00:00