Genetic characterization of human immunodeficiency virus type 1 in elite controllers: lack of gross genetic defects or common amino acid changes.

abstract：:Reverse transcription in avian sarcoma virus (ASV) initiates from the 3' end of a tRNA(Trp) primer, which anneals near the 5' end of the RNA genome. The region around the primer-binding site (PBS) forms an elaborate stem structure composed of the U5-inverted repeat (U5-IR) stem, the U5-leader stem, and the association...

journal_title：Journal of virology

authors： Morris S,Johnson M,Stavnezer E,Leis J

更新日期：2002-08-01 00:00:00

abstract：UNLABELLED:Influenza virus transcription requires functional coupling with cellular transcription for the cap-snatching process. Despite this fact, RNA polymerase II (RNAP II) is degraded during infection in a process triggered by the viral polymerase. Reassortant viruses from the A/PR/8/34 (PR8) strain that induce (hv...

journal_title：Journal of virology

authors： Llompart CM,Nieto A,Rodriguez-Frandsen A

更新日期：2014-03-01 00:00:00

abstract：:Expression of the hepatitis B virus core antigen (HBcAg) in mouse NIH 3T3 fibroblasts has been shown previously (A. McLachlan et al., J. Virol. 61:683-692, 1987) to result in the nuclear localization of this polypeptide. Since the carboxyl terminus of HBcAg contains four clusters of arginine residues which resemble nu...

journal_title：Journal of virology

authors： Eckhardt SG,Milich DR,McLachlan A

更新日期：1991-02-01 00:00:00

abstract：:Moloney murine leukemia virus (M-MuLV) and M-MuLV-derived retroviral vectors are not expressed in early mouse embryos or in embryonal carcinoma cells. M-MuLV-derived mutants or M-MuLV-related variants which transduce the neomycin phosphotransferase gene can, however, induce drug resistance in embryonal carcinoma cells...

journal_title：Journal of virology

authors： Weiher H,Barklis E,Ostertag W,Jaenisch R

更新日期：1987-09-01 00:00:00

abstract：UNLABELLED:To date, the response of teleost B cells to specific pathogens has been only scarcely addressed. In this work, we have demonstrated that viral hemorrhagic septicemia virus (VHSV), a fish rhabdovirus, has the capacity to infect rainbow trout spleen IgM-positive (IgM(+)) cells, although the infection is not pr...

journal_title：Journal of virology

authors： Abós B,Castro R,González Granja A,Havixbeck JJ,Barreda DR,Tafalla C

更新日期：2015-02-01 00:00:00

abstract：:Minute virus of canines (MVC) is a member of the genus Bocavirus in the family Parvoviridae. We have molecularly cloned and sequenced the 5'- and 3'-terminal palindromes of MVC. The MVC genome, 5,404 nucleotides (nt) in length, shared an identity of 52.6% and 52.1% with that of human bocavirus and bovine parvovirus, r...

journal_title：Journal of virology

authors： Sun Y,Chen AY,Cheng F,Guan W,Johnson FB,Qiu J

更新日期：2009-04-01 00:00:00

abstract：:Epstein-Barr Virus (EBV) generates a variety of viral microRNAs (miRNAs) by processing the BHRF1 and BamHI A rightward (BART) transcripts. BART miRNAs are expressed in all cells latently infected with EBV, but the functions of most BART miRNAs remain unknown. The results of a cell proliferation assay revealed that miR...

journal_title：Journal of virology

authors： Choi H,Lee H,Kim SR,Gho YS,Lee SK

更新日期：2013-07-01 00:00:00

abstract：:Vesicular stomatitis virus (VSV) is a negative-strand RNA virus with intrinsic oncolytic specificity due to substantially attenuated antiviral responses in many tumors. We have recently reported that recombinant VSV vector can be used as an effective oncolytic agent to safely treat multifocal hepatocellular carcinoma ...

journal_title：Journal of virology

authors： Shinozaki K,Ebert O,Suriawinata A,Thung SN,Woo SL

更新日期：2005-11-01 00:00:00

abstract：:This article has been retracted. ...

journal_title：Journal of virology

authors： He CQ,Ding NZ,Han GZ,Liu W

更新日期：2008-01-23 00:00:00

abstract：:Although hepatitis A virus (HAV) is typically transmitted by the fecal-oral route, little is known of its interactions with cells of the gastrointestinal tract. We studied the replication of HAV in polarized cultures of Caco-2 cells, a human cell line which retains many differentiated functions of small intestinal epi...

journal_title：Journal of virology

authors： Blank CA,Anderson DA,Beard M,Lemon SM

更新日期：2000-07-01 00:00:00

abstract：:Strains of Bacillus that harbor defective phage PBSX were found to be insensitive to SP-10(C), although the phage adsorbed to these insensitive strains. Strains that did not carry the phage were sensitive to SP-10(C). B. subtilis 168 ind(-), which can be tranduced by SP-10(C) but is nonpermissive for the phage, was re...

journal_title：Journal of virology

authors： Goldberg ID,Bryan T

更新日期：1968-08-01 00:00:00

abstract：:The viral early-to-late switch of papillomavirus infection is tightly linked to keratinocyte differentiation and is mediated in part by alternative mRNA splicing. Here, we report that SRp20, a cellular splicing factor, controls the early-to-late switch via interactions with A/C-rich RNA elements. An A/C-rich SE4 eleme...

journal_title：Journal of virology

authors： Jia R,Liu X,Tao M,Kruhlak M,Guo M,Meyers C,Baker CC,Zheng ZM

更新日期：2009-01-01 00:00:00

abstract：:Norovirus (NoV) infections are a leading cause of gastroenteritis. The humoral immune response plays an important role in the control of NoV, and recent studies have identified neutralizing antibodies that bind the capsid protein VP1 to block viral infection. Here, we utilize a NoV GI.1 Jun-Fos-assisted phage display ...

journal_title：Journal of virology

authors： Huang W,Soeung V,Boragine DM,Hu L,Prasad BVV,Estes MK,Atmar RL,Palzkill T

更新日期：2020-12-09 00:00:00

abstract：:Among several proposed cellular receptors for bovine viral diarrhea virus (BVDV), the low-density lipoprotein (LDL) receptor is of special interest because it is also considered a receptor for the related hepatitis C virus. It has been reported that an anti-LDL receptor monoclonal antibody blocked the infection of bov...

journal_title：Journal of virology

authors： Krey T,Moussay E,Thiel HJ,Rümenapf T

更新日期：2006-11-01 00:00:00

abstract：:We have developed idiotype-anti-idiotype monoclonal antibodies that provide evidence for rabies virus binding to the acetylcholine receptor (AChR). Hybridoma cell lines 7.12 and 7.25 resulted after fusion of NS-1 myeloma cells with spleen cells from a BALB/c mouse immunized with rabies virus strain CVS. Antibody 7.12 ...

journal_title：Journal of virology

authors： Hanham CA,Zhao F,Tignor GH

更新日期：1993-01-01 00:00:00

abstract：:Using gel shift assays, we found that the human immunodeficiency virus type 1 (HIV-1) Tat protein (Tat-1) bound both HIV-1 and HIV-2 TAR RNAs with similar high affinities. In contrast, the HIV-2 Tat protein (Tat-2) bound only TAR-2 RNA with high affinity. We conclude that the weak in vivo activity of Tat-2 on the HIV-...

journal_title：Journal of virology

authors： Rhim H,Rice AP

更新日期：1993-02-01 00:00:00

abstract：:n-(n-Nonyl)-deoxygalactonojirimycin (n,n-DGJ), an alkylated imino sugar, reduces the amount of HBV DNA produced within the stably transfected HBV-producing HepG2.2.15 line in culture and is under consideration for development as a human therapeutic. n,n-DGJ does not appear to inhibit HBV DNA polymerase activity or env...

journal_title：Journal of virology

authors： Lu X,Tran T,Simsek E,Block TM

更新日期：2003-11-01 00:00:00

abstract：:Foot-and-mouth disease virus (FMDV) nonstructural protein 3A plays important roles in virus replication, virulence, and host range. In other picornaviruses, homodimerization of 3A has been shown to be relevant for its biological activity. In this work, FMDV 3A homodimerization was evidenced by an in situ protein fluor...

journal_title：Journal of virology

authors： González-Magaldi M,Postigo R,de la Torre BG,Vieira YA,Rodríguez-Pulido M,López-Viñas E,Gómez-Puertas P,Andreu D,Kremer L,Rosas MF,Sobrino F

更新日期：2012-10-01 00:00:00

abstract：:The release of the ribonucleic acid (RNA)-containing phage MS2 from Escherichia coli is accompanied by cellular lysis at 37 C, whereas at 30 C phage are released from intact cells. Chloramphenicol or rifampin prevents the release of progeny phage particles at both temperatures. Neither drug causes an immediate cessati...

journal_title：Journal of virology

authors： Engelberg H,Soudry E

更新日期：1971-09-01 00:00:00

abstract：:Polyomaviruses are small nonenveloped particles with a circular double-stranded genome, approximately 5 kbp in size. The mammalian polyomaviruses mainly cause persistent subclinical infections in their natural nonimmunocompromised hosts. In contrast, the polyomaviruses of birds--avian polyomavirus (APV) and goose hemo...

journal_title：Journal of virology

authors： Johne R,Wittig W,Fernández-de-Luco D,Höfle U,Müller H

更新日期：2006-04-01 00:00:00

abstract：:Herpes simplex virus 2 (HSV-2) infection is still one of the common causes of sexually transmitted diseases worldwide. The prevalence of HSV strains resistant to traditional nucleoside antiviral agents has led to the development of novel antiviral drugs. Human alpha-defensin 5 (HD5), a kind of endogenous antimicrobial...

journal_title：Journal of virology

authors： Wang A,Chen F,Wang Y,Shen M,Xu Y,Hu J,Wang S,Geng F,Wang C,Ran X,Su Y,Cheng T,Wang J

更新日期：2013-03-01 00:00:00

abstract：:The E5 oncoprotein of bovine papillomavirus type 1 is a 44-amino-acid, hydrophobic polypeptide which localizes predominantly in Golgi membranes and appears to transform cells through the activation of tyrosine kinase growth factor receptors. In fibroblasts, E5 interacts with both the 16-kilodalton vacuolar ATPase subu...

journal_title：Journal of virology

authors： Sparkowski J,Mense M,Anders J,Schlegel R

更新日期：1996-04-01 00:00:00

abstract：:Both CD4(+) and CD8(+) T cells are required for clearance of the murine coronavirus mouse hepatitis virus (MHV) during acute infection. We investigated the effects of an epitope-specific CD8(+) T-cell response on acute infection of MHV, strain A59, in the murine CNS. Mice with CD8(+) T cells specific for gp33-41 (an H...

journal_title：Journal of virology

authors： Chua MM,MacNamara KC,San Mateo L,Shen H,Weiss SR

更新日期：2004-02-01 00:00:00

abstract：:To investigate the role of the hepatitis C virus internal ribosome entry site (HCV IRES) domain IV in translation initiation and regulation, two chimeric IRES elements were constructed to contain the reciprocal domain IV in the otherwise HCV and classical swine fever virus IRES elements. This permitted an examination ...

journal_title：Journal of virology

authors： Li D,Lott WB,Martyn J,Haqshenas G,Gowans EJ

更新日期：2004-11-01 00:00:00

abstract：UNLABELLED:Modified vaccinia virus Ankara (MVA) serves as a versatile platform in vaccine development. This highly attenuated orthopoxvirus, which cannot replicate in mammalian cells, triggers strong innate immune responses, including cell migration. Previously, we have shown that induction of chemokine (C-C motif) lig...

journal_title：Journal of virology

authors： Price PJ,Luckow B,Torres-Domínguez LE,Brandmüller C,Zorn J,Kirschning CJ,Sutter G,Lehmann MH

更新日期：2014-09-01 00:00:00

abstract：:Precursor polyproteins containing translational products of the gag gene of Moloney murine leukemia virus were purified by gel electrophoresis and cleaved into large fragments by hydroxylamine, mild acid hydrolysis, or cyanogen bromide. The hydroxylamine cleavage method (specific for asparagine-glycine bonds) was adap...

journal_title：Journal of virology

authors： Saris CJ,van Eenbergen J,Liskamp RM,Bloemers HP

更新日期：1983-06-01 00:00:00

abstract：:Intracellular simian virus 40 (SV40) chromatin was photoreacted with a 3H-labeled psoralen derivative, hydroxymethyltrimethylpsoralen (HMT), at 48 h postinfection. Psoralen compounds have been shown to readily penetrate intact cells and, in the presence of long-wavelength UV light, form covalent adducts to DNA, prefer...

journal_title：Journal of virology

authors： Robinson GW,Hallick LM

更新日期：1982-01-01 00:00:00

abstract：UNLABELLED:In contrast to many viruses, human cytomegalovirus (HCMV) is unable to productively infect most cancer-derived cell lines. The mechanisms of this restriction are unclear. To explore this issue, we tested whether defined oncogenic alleles, including the simian virus 40 (SV40) T antigen (TAg) and oncogenic H-R...

journal_title：Journal of virology

authors： Xu S,Schafer X,Munger J

更新日期：2016-04-14 00:00:00

abstract：:The EFII cis element is a 38-bp sequence at the 5' end of the Rous sarcoma virus long terminal repeat, extending from nucleotides -229 to -192 (with respect to the viral transcription start site), which is recognized by sequence-specific DNA-binding proteins in avian fibroblast nuclear extracts (L. Sealy and R. Chalkl...

journal_title：Journal of virology

authors： Sears RC,Sealy L

更新日期：1992-11-01 00:00:00

abstract：:Chronic hepatitis B affects over 300 million people who are at risk of developing liver cancer. The basis for the persistence of hepatitis B virus (HBV) in hepatocytes, even in the presence of available antiviral therapies, lies in the accumulation of covalently closed circular DNA (cccDNA) in nuclei of infected cells...

journal_title：Journal of virology

authors： Li M,Sohn JA,Seeger C

更新日期：2017-12-14 00:00:00