Control of the papillomavirus early-to-late switch by differentially expressed SRp20.

abstract：:High-risk human papillomavirus type 16 (HPV16) is the primary causative agent of cervical cancer and therefore is responsible for significant morbidity and mortality worldwide. Cellular transformation is mediated directly by the expression of viral oncogenes, the least characterized of which, E5, subverts cellular pro...

journal_title：Journal of virology

authors： Wetherill LF,Holmes KK,Verow M,Müller M,Howell G,Harris M,Fishwick C,Stonehouse N,Foster R,Blair GE,Griffin S,Macdonald A

更新日期：2012-05-01 00:00:00

abstract：:Ribonucleic acid extracted from influenza virus was labeled at the 3' termini with (3)H and analyzed by polyacrylamide gel electrophoresis. Influenza virus was found to contain a minimum of seven and possibly as many as 10 polynucleotide chains, most of which appear to terminate at the 3' end in uridine. ...

journal_title：Journal of virology

authors： Lewandowski LJ,Content J,Leppla SH

更新日期：1971-11-01 00:00:00

abstract：:A Sepharose 4B chromatographic method for purification of retroviruses is described which was less time consuming, increased purified virus yields, conserved viral glycoprotein, and increased recovery of biological infectivity in comparison with conventional sucrose gradient ultracentrifugation techniques. ...

journal_title：Journal of virology

authors： McGrath M,Witte O,Pincus T,Weissman IL

更新日期：1978-03-01 00:00:00

abstract：:The distantly related lentiviruses human immunodeficiency virus type 1 (HIV-1) and visna virus each encode a posttranscriptional regulatory protein, termed Rev, that is critical for expression of the viral structural proteins. We genetically mapped the cis-acting target sequence for visna virus Rev, the visna virus Re...

journal_title：Journal of virology

authors： Tiley LS,Cullen BR

更新日期：1992-06-01 00:00:00

abstract：:By marker rescue of bacteriophage SP02 sus mutants with purified bacteriophage SP02 DNA fragments, 11 of the 17 known bacteriophage SP02 sus loci were assigned to discrete DNA fragments. The left-most genetic locus, susA, was found to reside near one bacteriophage SP02 terminus (EcoRI-C1 fragment), whereas the right-m...

journal_title：Journal of virology

authors： Graham S,Sutton S,Yoneda Y,Young FE

更新日期：1982-04-01 00:00:00

abstract：:The major envelope glycoproteins gp120 and gp41 of human immunodeficiency virus type 1, the causative agent for human AIDS, contain numerous N-linked oligosaccharides. We report here our discovery that N-acetylglucosamine residues within the complex-type N-linked oligosaccharides of both gp120 and its precursor, gp160...

journal_title：Journal of virology

authors： Shilatifard A,Merkle RK,Helland DE,Welles JL,Haseltine WA,Cummings RD

更新日期：1993-02-01 00:00:00

abstract：:Nucleotide sequence analysis of two simian virus 40 early mutants dl1263 and dl1265, which lack a DNA segment around map positions 0.21 and 0.18, respectively (C. Cole, T. Landers, S. Goff, S. MAnteuil-Brutlag, and P. Berg, J. Virol. 24:277--294, 1977), revealed in-phase deletions of 33 nucleotide pairs for dl1263 and...

journal_title：Journal of virology

authors： Van Heuverswyn H,Cole C,Berg P,Fiers W

更新日期：1979-06-01 00:00:00

abstract：:Investigation of the human antibody response to the 1957 pandemic H2N2 influenza A virus has been largely limited to serologic studies. We generated five influenza virus hemagglutinin (HA)-reactive human monoclonal antibodies (MAbs) by hybridoma technology from the peripheral blood of healthy donors who were born betw...

journal_title：Journal of virology

authors： Krause JC,Tsibane T,Tumpey TM,Huffman CJ,Albrecht R,Blum DL,Ramos I,Fernandez-Sesma A,Edwards KM,García-Sastre A,Basler CF,Crowe JE Jr

更新日期：2012-06-01 00:00:00

abstract：:The virion host shutoff protein (vhs) of herpes simplex virus (HSV) triggers global shutoff of host protein synthesis and accelerated mRNA turnover during virus infection and induces endoribonucleolytic cleavage of exogenous RNA substrates when it is produced in a rabbit reticulocyte (RRL) in vitro translation system....

journal_title：Journal of virology

authors： Lu P,Jones FE,Saffran HA,Smiley JR

更新日期：2001-02-01 00:00:00

abstract：UNLABELLED:Viruses that spread systemically from a peripheral site of infection cause morbidity and mortality in the human population. Innate myeloid cells, including monocytes, macrophages, monocyte-derived dendritic cells (mo-DC), and dendritic cells (DC), respond early during viral infection to control viral replica...

journal_title：Journal of virology

authors： Kaminsky LW,Sei JJ,Parekh NJ,Davies ML,Reider IE,Krouse TE,Norbury CC

更新日期：2015-10-01 00:00:00

abstract：:Sequences from the 5' end of type 1 human immunodeficiency virus RNA dimerize spontaneously in vitro in a reaction thought to mimic the initial step of genomic dimerization in vivo. Dimer initiation has been proposed to occur through a "kissing-loop" interaction involving a specific RNA stem-loop element designated SL...

journal_title：Journal of virology

authors： Clever JL,Wong ML,Parslow TG

更新日期：1996-09-01 00:00:00

abstract：:Adeno-associated virus type 2 (AAV-2) gene expression is tightly controlled by functions of the helper virus as well as by the products of its own viral rep gene. Double-immunofluorescence studies of Rep and VP protein expression in cells coinfected with AAV-2 and adenovirus type 2 showed that a large proportion of th...

journal_title：Journal of virology

authors： Weger S,Wistuba A,Grimm D,Kleinschmidt JA

更新日期：1997-11-01 00:00:00

abstract：:We analyzed the susceptibility of 10 AKXD recombinant inbred (RI) mouse strains to lymphomas. These strains were derived from crosses of AKR/J, a highly lymphomatous strain, and DBA/2J, a weakly lymphomatous strain. Of the 10 strains analyzed, nine showed a high incidence of lymphoma development. As with the other 13 ...

journal_title：Journal of virology

authors： Gilbert DJ,Neumann PE,Taylor BA,Jenkins NA,Copeland NG

更新日期：1993-04-01 00:00:00

abstract：:The nodavirus flock house virus (FHV) has a bipartite, positive-sense, RNA genome that encodes the catalytic subunit of the RNA replicase and the viral capsid protein precursor on separate genomic segments (RNA1 and RNA2, respectively). RNA1 can replicate autonomously when transfected into permissive cells, allowing s...

journal_title：Journal of virology

authors： Johnson KL,Ball LA

更新日期：1999-10-01 00:00:00

abstract：:A large number of polyoma virus-transformed cells of rat, mouse, and hamster origin were examined for presence of T-antigen species. The results showed that all lines of cells contained middle and small T antigens, but not all contained a full-sized large T antigen, in some cell lines large T antigen was absent, where...

journal_title：Journal of virology

authors： Ito Y,Spurr N,Griffin BE

更新日期：1980-07-01 00:00:00

abstract：:Coronavirus nonstructural protein 8 (nsp8) has been suggested to have diverse activities, including noncanonical template-dependent polymerase activities. Here, we characterized a recombinant form of the human coronavirus 229E (HCoV-229E) nsp8 and found that the protein has metal ion-dependent RNA 3'-terminal adenylyl...

journal_title：Journal of virology

authors： Tvarogová J,Madhugiri R,Bylapudi G,Ferguson LJ,Karl N,Ziebuhr J

更新日期：2019-05-29 00:00:00

abstract：:Based on sequence divergence in the transformation-relevant region, herpesvirus saimiri strains are classified into three subgroups. Only members of subgroup C transform human T lymphocytes to continuous interleukin-2-dependent growth in culture. In this study, human cord blood T cells were immortalized by using diffe...

journal_title：Journal of virology

authors： Fickenscher H,Bökel C,Knappe A,Biesinger B,Meinl E,Fleischer B,Fleckenstein B,Bröker BM

更新日期：1997-03-01 00:00:00

abstract：:The expression strategy of parvoviruses of the Densovirus genus has as yet not been reported. Clones were obtained from the densonucleosis virus of Galleria mellonella (GmDNV) that yielded infectious virus upon transfection into LD652 cells. Its genome was found to be the longest (6,039 nucleotides [nt]), with the lar...

journal_title：Journal of virology

authors： Tijssen P,Li Y,El-Far M,Szelei J,Letarte M,Zádori Z

更新日期：2003-10-01 00:00:00

abstract：:Human T-cell lymphotropic virus type 1 (HTLV-1) enhances the growth of T lymphocytes, allowing the generation of T-lymphocyte cell lines. This report describes a limiting-dilution assay system which uses low input numbers of HTLV-1-producing cells for generation of T-lymphocyte cultures. The HTLV-1 transformants gener...

journal_title：Journal of virology

authors： Persaud D,Muñoz JL,Tarsis SL,Parks ES,Parks WP

更新日期：1995-10-01 00:00:00

abstract：:A mouse model of high-risk human papillomavirus infection was developed in which human papillomavirus (HPV) type 16 DNA was inoculated into human foreskin grafted to the skin of severe combined immunodeficient (scid) mice. Grafted skin contained human epidermis and dermis and, like normal human skin, expressed involuc...

journal_title：Journal of virology

authors： Brandsma JL,Brownstein DG,Xiao W,Longley BJ

更新日期：1995-04-01 00:00:00

abstract：:Viruses commonly antagonize the antiviral type I interferon response by targeting signal transducer and activator of transcription 1 (STAT1) and STAT2, key mediators of interferon signaling. Other STAT family members mediate signaling by diverse cytokines important to infection, but their relationship with viruses is ...

journal_title：Journal of virology

authors： Harrison AR,Moseley GW

更新日期：2020-10-27 00:00:00

abstract：:In this study, we show that replication-competent subgenomic hepatitis C virus (HCV) RNA can be transferred to permissive Huh7 cells, leading to the establishment of viral RNA replication. Further, we show that these events are mediated by exosomes rather than infectious virus particles. If similar events occur in viv...

journal_title：Journal of virology

authors： Longatti A,Boyd B,Chisari FV

更新日期：2015-03-01 00:00:00

abstract：:Human oncolytic adenoviruses have been used in clinical trials targeting cancers of epithelial origin. To gain a better understanding of the infectious cycle of adenovirus in normal human squamous tissues, we examined the viral infection process in organotypic cultures of primary human keratinocytes. We show that for ...

journal_title：Journal of virology

authors： Noya F,Balagué C,Banerjee NS,Curiel DT,Broker TR,Chow LT

更新日期：2003-06-01 00:00:00

abstract：:The human immunodeficiency virus type 1 (HIV-1) Tat protein, which is essential for HIV gene expression and viral replication, is known to mediate pleiotropic effects on various cell functions. For instance, Tat protein is able to regulate the rate of transcription of host cellular genes and to interact with the signa...

journal_title：Journal of virology

authors： Calzado MA,Sancho R,Muñoz E

更新日期：2004-07-01 00:00:00

abstract：:Antigens derived from host cells are detectable in the envelope of human immunodeficiency virus type 1 (HIV-1) and result in a distinctive viral phenotype reflecting that of the host cell. An immunomagnetic capture assay targeting discriminatory host proteins was developed to differentiate between HIV-1 derived from m...

journal_title：Journal of virology

authors： Lawn SD,Roberts BD,Griffin GE,Folks TM,Butera ST

更新日期：2000-01-01 00:00:00

abstract：:To map the DNA-binding domain of polyomavirus large T antigen, we constructed a set of plasmids coding for unidirectional carboxy- or amino-terminal deletion mutations in the large T antigen. Analysis of origin-specific DNA binding by mutant proteins expressed in Cos-1 cells revealed that the C-terminal boundary of th...

journal_title：Journal of virology

authors： Sunstrom NA,Acheson NH,Hassell JA

更新日期：1991-12-01 00:00:00

abstract：:The hepatitis A virus (HAV) internal ribosome entry segment (IRES) is unique among the picornavirus IRESs in that it is inactive in the presence of either the entero- and rhinovirus 2A or aphthovirus Lb proteinases. Since these proteinases both cleave eukaryotic initiation factor 4G (eIF4G) and HAV IRES activity could...

journal_title：Journal of virology

authors： Borman AM,Michel YM,Kean KM

更新日期：2001-09-01 00:00:00

abstract：:Lack of disease in long-term nonprogressors with human immunodeficiency virus type 1 (HIV-1) infection was strongly associated with very low copy numbers of HIV-1 DNA and RNA in peripheral blood mononuclear cells and plasma and the presence of high levels of anti-HIV-1 CD8+ memory cytotoxic T lymphocytes specific for ...

journal_title：Journal of virology

authors： Rinaldo C,Huang XL,Fan ZF,Ding M,Beltz L,Logar A,Panicali D,Mazzara G,Liebmann J,Cottrill M

更新日期：1995-09-01 00:00:00

abstract：:Mutations introduced into the capsid gene of duck hepatitis B virus (DHBV) were tested for their effects on viral DNA synthesis and assembly of enveloped viruses. Four classes of mutant phenotypes were observed among a series of deletions of covering the 3' end of the capsid open reading frame. Class I mutant capsids ...

journal_title：Journal of virology

authors： Yu M,Summers J

更新日期：1991-05-01 00:00:00

abstract：:Human papillomavirus (HPV) is a strongly conserved DNA virus, high-risk types of which can cause cervical cancer in persistent infections. The most common type found in HPV-attributable cancer is HPV16, which can be subdivided into four lineages (A to D) with different carcinogenic properties. Studies have shown HPV16...

journal_title：Journal of virology

authors： van der Weele P,Meijer CJLM,King AJ

更新日期：2017-09-12 00:00:00