Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses.

abstract：:Myxomatosis is a recurrent problem on rabbit farms throughout Europe despite the success of vaccines. To identify gene variations of field and vaccine strains that may be responsible for changes in virulence, immunomodulation, and immunoprotection, the genomes of 6 myxoma virus (MYXV) strains were sequenced: German fi...

journal_title：Journal of virology

authors： Braun C,Thürmer A,Daniel R,Schultz AK,Bulla I,Schirrmeier H,Mayer D,Neubert A,Czerny CP

更新日期：2017-01-31 00:00:00

abstract：:Shrimp subcuticular epithelial cells are the initial and major targets of white spot syndrome virus (WSSV) infection. Proteomic studies of WSSV-infected subcuticular epithelium of Penaeus monodon were performed through two approaches, namely, subcellular fractionation coupled with shotgun proteomics to identify viral ...

journal_title：Journal of virology

authors： Wu J,Lin Q,Lim TK,Liu T,Hew CL

更新日期：2007-11-01 00:00:00

abstract：:Adenovirus (Ad) entry into cells is initiated by the binding of the fiber knob to a cell surface receptor. The coxsackie- and adenovirus receptor (CAR) functions as the attachment receptor for many, but not all, Ad serotypes. Ad type 37 (Ad37), a subgroup D virus that causes keratoconjunctivitis in humans, does not in...

journal_title：Journal of virology

authors： Chiu CY,Wu E,Brown SL,Von Seggern DJ,Nemerow GR,Stewart PL

更新日期：2001-06-01 00:00:00

abstract：:Induction of the resident prophage did not permit restricted phage T1 to replicate freely in P1-lysogenic hosts. A few induced cells did become infectible. ...

journal_title：Journal of virology

authors： Christensen JR,Werner ER

更新日期：1969-04-01 00:00:00

abstract：:Bovine leukemia virus (BLV) from either persistently infected bat cells or fetal lamb kidney cells induced rapid syncytium formation in F81 indicator cells. Distinct syncytia were seen within 2 h after inoculation of cells with highly concentrated (500-fold) cell-free BLV preparations and within 4 to 8 h when unconcen...

journal_title：Journal of virology

authors： Graves DC,Jones LV

更新日期：1981-06-01 00:00:00

abstract：:Adaptation of field isolates of foot-and-mouth disease virus (FMDV) to grow in cells in culture can result in changes in viral properties that include acquisition of the ability to bind to cell surface heparan sulfate (HS). After 13 passages on BHK cells to produce a vaccine, a Cathay topotype isolate of FMDV serotype...

journal_title：Journal of virology

authors： Zhao Q,Pacheco JM,Mason PW

更新日期：2003-03-01 00:00:00

abstract：:Several point mutations in the simian virus 40 (SV40) small-t antigen have been analyzed for their effects on protein stability, transformation, transactivation, and binding of two cellular proteins. All mutations which affected cysteine residues in two cysteine clusters produced highly unstable small-t antigens. Four...

journal_title：Journal of virology

authors： Jog P,Joshi B,Dhamankar V,Imperiale MJ,Rutila J,Rundell K

更新日期：1990-06-01 00:00:00

abstract：:When human A431 cells, which carry high numbers of epidermal growth factor (EGF) receptors, are exposed to EGF, the total content of phosphotyrosine in cell protein is increased, the EGF receptor becomes phosphorylated at tyrosine, and new phosphotyrosine-containing 36,000- and 81,000-dalton proteins are detected. We ...

journal_title：Journal of virology

authors： Cooper JA,Scolnick EM,Ozanne B,Hunter T

更新日期：1983-12-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1)-infected macrophages damage mature neurons in the brain, although their effect on neuronal development has not been clarified. In this study, we show that HIV-1-infected macrophages produce factors that impair the development of neuronal precursor cells and that soluble vira...

journal_title：Journal of virology

authors： Kitayama H,Miura Y,Ando Y,Hoshino S,Ishizaka Y,Koyanagi Y

更新日期：2008-03-01 00:00:00

abstract：:All human influenza pandemics have originated from avian influenza viruses. Although multiple changes are needed for an avian virus to be able to transmit between humans, binding to human-type receptors is essential. Several research groups have reported mutations in H5N1 viruses that exhibit specificity for human-typ...

journal_title：Journal of virology

authors： Peng W,Bouwman KM,McBride R,Grant OC,Woods RJ,Verheije MH,Paulson JC,de Vries RP

更新日期：2018-04-27 00:00:00

abstract：:Human MxA protein accumulates in the cytoplasm of interferon-treated cells and inhibits the multiplication of several RNA viruses, including Thogoto virus (THOV), a tick-borne orthomyxovirus that transcribes and replicates its genome in the cell nucleus. The antiviral mechanism of MxA was investigated by using two alt...

journal_title：Journal of virology

authors： Weber F,Haller O,Kochs G

更新日期：2000-01-01 00:00:00

abstract：UNLABELLED:The genome of nonsegmented negative-strand RNA viruses is tightly embedded within a nucleocapsid made of a nucleoprotein (N) homopolymer. To ensure processive RNA synthesis, the viral polymerase L in complex with its cofactor phosphoprotein (P) binds the nucleocapsid that constitutes the functional template....

journal_title：Journal of virology

authors： Brunel J,Chopy D,Dosnon M,Bloyet LM,Devaux P,Urzua E,Cattaneo R,Longhi S,Gerlier D

更新日期：2014-09-01 00:00:00

abstract：:Highly pathogenic influenza A viruses (IAV) from avian hosts were first reported to directly infect humans 20 years ago. However, such infections are rare events, and our understanding of factors promoting or restricting zoonotic transmission is still limited. One accessory protein of IAV, PB1-F2, was associated with ...

journal_title：Journal of virology

authors： Mazel-Sanchez B,Boal-Carvalho I,Silva F,Dijkman R,Schmolke M

更新日期：2018-05-14 00:00:00

abstract：:The Coccolithoviridae are a group of viruses which infect the marine coccolithophorid microalga Emiliania huxleyi. The Emiliania huxleyi viruses (known as EhVs) described herein have 160- to 180-nm diameter icosahedral structures, have genomes of approximately 400 kbp, and consist of more than 450 predicted coding seq...

journal_title：Journal of virology

authors： Nissimov JI,Worthy CA,Rooks P,Napier JA,Kimmance SA,Henn MR,Ogata H,Allen MJ

更新日期：2012-03-01 00:00:00

abstract：:The DNA sequence of 3,240 nucleotides of the XbaI G fragment located in the unique long (UL) region of the equine herpesvirus 1 genome revealed two major open reading frames (ORFs) designated UL3 and UL4. The UL3 ORF of 470 amino acids (aa) maps at nucleotides (nt) 4450 to 3038 from the long terminus, and its predicte...

journal_title：Journal of virology

authors： Zhao Y,Holden VR,Harty RN,O'Callaghan DJ

更新日期：1992-09-01 00:00:00

abstract：:Herpes simplex virus (HSV) fusion with cells requires the gD, gB, and gH/gL glycoprotein quartet. gD serves as a receptor binding glycoprotein. gB and gH/gL execute fusion in an as-yet-unclear manner. To better understand the role of gH/gL in HSV entry, we produced a soluble version of gH/gL carrying a One-STrEP tag (...

journal_title：Journal of virology

authors： Gianni T,Cerretani A,Dubois R,Salvioli S,Blystone SS,Rey F,Campadelli-Fiume G

更新日期：2010-04-01 00:00:00

abstract：:Lassa fever (LF) is a zoonotic viral hemorrhagic fever caused by Lassa virus (LASV), which is endemic to West African countries. Previous studies have suggested an important role for T-cell-mediated immunopathology in LF pathogenesis, but the mechanisms by which T cells influence disease severity and outcome are not w...

journal_title：Journal of virology

authors： Port JR,Wozniak DM,Oestereich L,Pallasch E,Becker-Ziaja B,Müller J,Rottstegge M,Olal C,Gómez-Medina S,Oyakhliome J,Ighodalo Y,Omomoh E,Olokor T,Adomeh DI,Asogun D,Ogbani-Emovon E,Hartmann K,Krasemann S,Nelson EV,Esc

更新日期：2020-10-14 00:00:00

abstract：:Tetherin (CD317/BST-2), an interferon-induced membrane protein, restricts the release of nascent retroviral particles from infected cell surfaces. While human immunodeficiency virus type 1 (HIV-1) encodes the accessory gene vpu to overcome the action of tetherin, the lineage of primate lentiviruses that gave rise to H...

journal_title：Journal of virology

authors： Le Tortorec A,Neil SJ

更新日期：2009-11-01 00:00:00

abstract：:Endocytosis and endosomal trafficking regulate the proteins targeted to the plasma membrane and play essential roles in diverse cellular processes, including responses to pathogen attack. Here, we report the identification of Glycine max (soybean) endocytosis dynamin-like protein 5A (GmSDL5A) associated with purified ...

journal_title：Journal of virology

authors： Wu G,Cui X,Chen H,Renaud JB,Yu K,Chen X,Wang A

更新日期：2018-11-12 00:00:00

abstract：UNLABELLED:Next-generation sequence analysis of virus-like particles (VLPs) produced during agroinfiltration of cucumber necrosis virus (CNV) coat protein (CP) and of authentic CNV virions was conducted to assess if host RNAs can be encapsidated by CNV CP. VLPs containing host RNAs were found to be produced during agro...

journal_title：Journal of virology

authors： Ghoshal K,Theilmann J,Reade R,Maghodia A,Rochon D

更新日期：2015-11-01 00:00:00

abstract：:Molecular clones of the subgroup A feline leukemia virus FeLV-A/Glasgow-1 have been obtained. Nucleotide sequence analysis of the 3' end of the proviral genome and comparison with the published sequence of FeLV-B/Gardner-Arnstein showed that the most extensive differences are located within the 5' domain of the env ge...

journal_title：Journal of virology

authors： Stewart MA,Warnock M,Wheeler A,Wilkie N,Mullins JI,Onions DE,Neil JC

更新日期：1986-06-01 00:00:00

abstract：:We characterized human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins (Env) isolated from two HIV-1-infected CCR5delta32 homozygotes. Envs from both subjects used CCR5 and CXCR4 for entry into transfected cells. Most R5X4 Envs were lymphocyte-tropic and used CXCR4 exclusively for entry into peripheral bl...

journal_title：Journal of virology

authors： Gray L,Churchill MJ,Keane N,Sterjovski J,Ellett AM,Purcell DF,Poumbourios P,Kol C,Wang B,Saksena NK,Wesselingh SL,Price P,French M,Gabuzda D,Gorry PR

更新日期：2006-04-01 00:00:00

abstract：:Broad, multispecific CD4(+) and CD8(+) T-cell responses to the hepatitis C virus (HCV), as well as virus-cross-neutralizing antibodies, are associated with recovery from acute infection and may also be associated in chronic HCV patients with a favorable response to antiviral treatment. In order to recapitulate all of ...

journal_title：Journal of virology

authors： Lin Y,Kwon T,Polo J,Zhu YF,Coates S,Crawford K,Dong C,Wininger M,Hall J,Selby M,Coit D,Medina-Selby A,McCoin C,Ng P,Drane D,Chien D,Han J,Vajdy M,Houghton M

更新日期：2008-08-01 00:00:00

abstract：:The hepatitis C virus (HCV) causes chronic hepatitis in most infected individuals by evading host immune defenses. In this investigation, we show that HCV-infected cells may go undetected in the immune system by suppressing major histocompatibility complex (MHC) class I antigen presentation to cytotoxic T lymphocytes....

journal_title：Journal of virology

authors： Tardif KD,Siddiqui A

更新日期：2003-11-01 00:00:00

abstract：:The VP6 protein of bluetongue virus possesses a number of activities, including nucleoside triphosphatase, RNA binding, and helicase activity (N. Stauber, J. Martinez-Costas, G. Sutton, K. Monastyrskaya, and P. Roy, J. Virol. 71:7220-7226, 1997). Although the enzymatic functions of the protein have been documented, a ...

journal_title：Journal of virology

authors： Kar AK,Roy P

更新日期：2003-11-01 00:00:00

abstract：:The chimpanzee is the only animal model for investigating the pathogenesis of viral hepatitis types A through E in humans. Studies of the host response, including microarray analyses, have relied on the close relationship between these two primate species: chimpanzee samples are commonly tested with human-based reagen...

journal_title：Journal of virology

authors： Yu C,Boon D,McDonald SL,Myers TG,Tomioka K,Nguyen H,Engle RE,Govindarajan S,Emerson SU,Purcell RH

更新日期：2010-11-01 00:00:00

abstract：:We have previously reported on the ubiquitylation and degradation of hepatitis C virus core protein. Here we demonstrate that proteasomal degradation of the core protein is mediated by two distinct mechanisms. One leads to polyubiquitylation, in which lysine residues in the N-terminal region are preferential ubiquityl...

journal_title：Journal of virology

authors： Suzuki R,Moriishi K,Fukuda K,Shirakura M,Ishii K,Shoji I,Wakita T,Miyamura T,Matsuura Y,Suzuki T

更新日期：2009-03-01 00:00:00

abstract：:The internal deletion mutant (DI-LT) derived from the heat-resistant strain of vesicular stomatitis virus synthesizes an aberrant polyadenylated mRNA (G*) containing a transcript of the partially deleted polymerase gene covalently linked to the 3' end of the glycoprotein message (R. C. Herman and R. A. Lazzarini, J. V...

journal_title：Journal of virology

authors： Herman RC

更新日期：1983-06-01 00:00:00

abstract：:A nucleotide phosphohydrolase is firmly associated with a purified polyhedral cytoplasmic deoxyvirus, frog virus 3. This adenosine triphosphatase is distinguishable from known mammalian cell adenosine triphosphatases and from adenosine triphosphatase of an unrelated cytoplasmic replicating virus grown in the same host...

journal_title：Journal of virology

authors： Vilagines R,McAuslan BR

更新日期：1971-05-01 00:00:00

abstract：:Enterovirus 71 (EV71) (genus Enterovirus, family Picornaviridae), a common cause of hand, foot, and mouth disease (HFMD), may also cause severe neurological diseases, such as encephalitis and poliomyelitis-like paralysis. To examine the genetic diversity and rate of evolution of EV71, we have determined and analyzed c...

journal_title：Journal of virology

authors： Brown BA,Oberste MS,Alexander JP Jr,Kennett ML,Pallansch MA

更新日期：1999-12-01 00:00:00