Baboon virus isolate M-7 with properties similar to feline virus RD-114.

abstract：:Inhibition of hepatitis B virus (HBV) replication and viral clearance from an infected host requires both the innate and adaptive immune responses. Expression of interferon (IFN)-inducible proteasome catalytic and regulatory subunits correlates with the IFN-alpha/beta- and IFN-gamma-mediated noncytopathic inhibition o...

journal_title：Journal of virology

authors： Robek MD,Garcia ML,Boyd BS,Chisari FV

更新日期：2007-01-01 00:00:00

abstract：:RNA plant viruses use various translational regulatory mechanisms to control their gene expression. Translational enhancement of viral mRNAs that leads to higher levels of protein synthesis from specific genes may be essential for the virus to successfully compete for cellular translational machinery. The control elem...

journal_title：Journal of virology

authors： Koh DC,Liu DX,Wong SM

更新日期：2002-02-01 00:00:00

abstract：:Cytoplasmic virus-specific RNA and polyribosomes from a chronically infected feline thymus tumor cell line, F-422, were analyzed by using in vitro-synthesized feline leukemia virus (Rickard strain) (R-FeLV) complementary DNA (cDNA) probe. By hybridization kinetics analysis, cytoplasmic, polyribosomat, and nuclear RNAs...

journal_title：Journal of virology

authors： Conely AJ,Velicer LF

更新日期：1978-03-01 00:00:00

abstract：:Initiation of the Epstein-Barr virus (EBV) lytic cycle is dependent on expression of the viral transactivator Zta, which is encoded by the BZLF1 gene. Described here is an initial mapping of the regions of Zta involved in activating transcription. The data indicate that the amino-terminal 153 amino acids of Zta are im...

journal_title：Journal of virology

authors： Flemington EK,Borras AM,Lytle JP,Speck SH

更新日期：1992-02-01 00:00:00

abstract：:The host structural maintenance of chromosomes 5/6 complex (Smc5/6) suppresses hepatitis B virus (HBV) transcription. HBV counters this restriction by expressing the X protein (HBx), which redirects the cellular DNA damage-binding protein 1 (DDB1)-containing E3 ubiquitin ligase to target Smc5/6 for degradation. Howeve...

journal_title：Journal of virology

authors： Ramakrishnan D,Xing W,Beran RK,Chemuru S,Rohrs H,Niedziela-Majka A,Marchand B,Mehra U,Zábranský A,Doležal M,Hubálek M,Pichová I,Gross ML,Kwon HJ,Fletcher SP

更新日期：2019-07-30 00:00:00

abstract：:In order to elucidate the molecular mechanisms of action of the tat-responsive sequence, mutational analysis of the tat-responsive sequence was carried out. The most critical region comprised nucleotides +18 to +44 and included the 3-nucleotide bulge at positions +23 to +25, the loop sequence, and an intact stem. In a...

journal_title：Journal of virology

authors： Roy S,Parkin NT,Rosen C,Itovitch J,Sonenberg N

更新日期：1990-03-01 00:00:00

abstract：UNLABELLED:Hepadnaviruses (hepatitis B viruses [HBVs]) are the only animal viruses that replicate their DNA by reverse transcription of an RNA intermediate. Until recently, the known host range of hepadnaviruses was limited to mammals and birds. We obtained and analyzed the first amphibian HBV genome, as well as severa...

journal_title：Journal of virology

authors： Dill JA,Camus AC,Leary JH,Di Giallonardo F,Holmes EC,Ng TF

更新日期：2016-08-12 00:00:00

abstract：:The Nef proteins of human immunodeficiency virus and simian immunodeficiency virus (SIV) bind the AP-1 and AP-2 clathrin adaptors to downmodulate the expression of CD4 and CD28 by recruiting them to sites of AP-2 clathrin-dependent endocytosis. Additionally, SIV Nef directly binds the CD3-zeta subunit of the CD3 compl...

journal_title：Journal of virology

authors： Swigut T,Greenberg M,Skowronski J

更新日期：2003-07-01 00:00:00

abstract：:Bovine herpesvirus 1 (BHV-1) is an important pathogen of cattle, and infection is usually initiated via the ocular or nasal cavity. Following acute infection, the primary site for BHV-1 latency is the sensory neuron. Reactivation from latency occurs sporadically, resulting in virus shedding and transmission to uninfec...

journal_title：Journal of virology

authors： Inman M,Lovato L,Doster A,Jones C

更新日期：2002-07-01 00:00:00

abstract：:The efficient attachment of pseudorabies virus to cultured cells is dependent on an electrostatic interaction between negatively charged cell surface heparan sulfate and the viral envelope glycoprotein gC. Deletion of the first one-third of gC severely impairs virus attachment, but the mutant virions are still capable...

journal_title：Journal of virology

authors： Flynn SJ,Ryan P

更新日期：1995-02-01 00:00:00

abstract：:Worldwide amphibian population declines have been ascribed to global warming, increasing pollution levels, and other factors directly related to human activities. These factors may additionally be favoring the emergence of novel pathogens. In this report, we have determined the complete genome sequence of the emerging...

journal_title：Journal of virology

authors： Mavian C,López-Bueno A,Balseiro A,Casais R,Alcamí A,Alejo A

更新日期：2012-04-01 00:00:00

abstract：:The cytolytic T-lymphocyte (CTL) response to respiratory infection with equine herpesvirus 1 (EHV-1) in CBA (H-2(k)) mice was investigated. Intranasal (i.n.) inoculation of mice with the attenuated EHV-1 strain KyA resulted in the generation of a primary virus-specific CTL response in the draining mediastinal lymph no...

journal_title：Journal of virology

authors： Smith PM,Zhang Y,Jennings SR,O'Callaghan DJ

更新日期：1998-07-01 00:00:00

abstract：:The recently developed subgenomic hepatitis C virus (HCV) replicons were limited by the fact that the sequence encoding the structural proteins was missing. Therefore, important information about a possible influence of these proteins on replication and pathogenesis and about the mechanism of virus formation could not...

journal_title：Journal of virology

authors： Pietschmann T,Lohmann V,Kaul A,Krieger N,Rinck G,Rutter G,Strand D,Bartenschlager R

更新日期：2002-04-01 00:00:00

abstract：:Antigens detected by the complement-fixation (CF) test were prepared from BHK-21 cells infected with Pichinde virus. The preparations contained two antigens demonstrable by immunodiffusion. The antigen present in abundance was heat stable, Pronase resistant, and had a molecular weight of 20,000 to 30,000 as estimated ...

journal_title：Journal of virology

authors： Buchmeier MJ,Gee SR,Rawls WE

更新日期：1977-04-01 00:00:00

abstract：:N-terminal modifications of the chemokine RANTES bind to C-C chemokine receptor 5 (CCR5) and block human immunodeficiency virus type 1 (HIV-1) infection with greater efficacy than native RANTES. Modified RANTES compounds induce rapid CCR5 internalization and much slower receptor reexpression than native RANTES, sugges...

journal_title：Journal of virology

authors： Sabbe R,Picchio GR,Pastore C,Chaloin O,Hartley O,Offord R,Mosier DE

更新日期：2001-01-01 00:00:00

abstract：:The Arabidopsis flowering locus T (FT) gene encodes the mobile florigen essential for floral induction. While movement of the FT protein has been shown to occur within plants, systemic spread of FT mRNA remains to be unequivocally demonstrated. Utilizing novel RNA mobility assay vectors based on two distinct movement-...

journal_title：Journal of virology

authors： Li C,Zhang K,Zeng X,Jackson S,Zhou Y,Hong Y

更新日期：2009-04-01 00:00:00

abstract：:Transcription of herpesviral late genes is stimulated after the onset of viral DNA replication but otherwise restricted. Late gene expression in gammaherpesviruses requires the coordination of six early viral proteins, termed viral transactivation factors (vTFs). Here, we mapped the organization of this protein comple...

journal_title：Journal of virology

authors： Davis ZH,Hesser CR,Park J,Glaunsinger BA

更新日期：2015-10-14 00:00:00

abstract：:West Nile virus (WNV) is a neurotropic mosquito-borne flavivirus of global importance. Neuroinvasive WNV infection results in encephalitis and can lead to prolonged neurological impairment or death. Type I interferon (IFN-I) is crucial for promoting antiviral defenses through the induction of antiviral effectors, whic...

journal_title：Journal of virology

authors： O'Neal JT,Upadhyay AA,Wolabaugh A,Patel NB,Bosinger SE,Suthar MS

更新日期：2019-03-05 00:00:00

abstract：:Vaccine-induced memory T cells localized at mucosal sites can provide rapid protection from viral infection. All-trans-retinoic acid (ATRA) has been shown to act physiologically to induce the expression of gut-homing receptors on lymphocytes. We tested whether the administration of exogenous ATRA during a systemic vac...

journal_title：Journal of virology

authors： Tan X,Sande JL,Pufnock JS,Blattman JN,Greenberg PD

更新日期：2011-08-01 00:00:00

abstract：:We previously described that type B retrovirus-like particles released from the human mammary carcinoma cell line T47D are pseudotypes and package retroviral RNA of different origins (W. Seifarth, H. Skladny, F. Krieg-Schneider, A. Reichert, R. Hehlmann, and C. Leib-Mösch, J. Virol. 69:6408-6416, 1995). One preferenti...

journal_title：Journal of virology

authors： Seifarth W,Baust C,Murr A,Skladny H,Krieg-Schneider F,Blusch J,Werner T,Hehlmann R,Leib-Mösch C

更新日期：1998-10-01 00:00:00

abstract：UNLABELLED:Rotaviruses (RVs) are 11-segmented, double-stranded RNA viruses that cause severe gastroenteritis in children. In addition to an error-prone genome replication mechanism, RVs can increase their genetic diversity by reassorting genes during host coinfection. Such exchanges allow RVs to acquire advantageous ge...

journal_title：Journal of virology

authors： Zhang S,McDonald PW,Thompson TA,Dennis AF,Akopov A,Kirkness EF,Patton JT,McDonald SM

更新日期：2014-09-01 00:00:00

abstract：:The functions of delta antigens (HDAgs) in the morphogenesis of hepatitis delta virus (HDV) have been studied previously. The C terminus of large HDAg has been shown to complex with the small surface antigen (HBsAg) of helper hepatitis B virus, whereas the assembly of small HDAg requires interaction with the N terminu...

journal_title：Journal of virology

authors： Chang MF,Chen CH,Lin SL,Chen CJ,Chang SC

更新日期：1995-04-01 00:00:00

abstract：:Retroviral capsid assembly can occur by either of two distinct morphogenic processes: in type C viruses, the capsid assembles and buds at the plasma membrane, while in type B and D viruses, the capsid assembles within the cytoplasm and is then transported to the plasma membrane for budding. We have previously reported...

journal_title：Journal of virology

authors： Choi G,Park S,Choi B,Hong S,Lee J,Hunter E,Rhee SS

更新日期：1999-07-01 00:00:00

abstract：:Alphavirus expression systems based on suicidal virus particles carrying recombinant replicons have proven to be a very efficient way to deliver genes for heterologous protein expression. However, present strategies for production of such particles have biosafety limitations due to the generation, by RNA recombination...

journal_title：Journal of virology

authors： Smerdou C,Liljeström P

更新日期：1999-02-01 00:00:00

abstract：:The localization of the adenovirus type 5 34-kDa E4 and 55-kDa E1B proteins was determined in the absence of other adenovirus proteins. When expressed by transfection in human, monkey, hamster, rat, and mouse cell lines, the E1B protein was predominantly cytoplasmic and typically was excluded from the nucleus. When ex...

journal_title：Journal of virology

authors： Goodrum FD,Shenk T,Ornelles DA

更新日期：1996-09-01 00:00:00

abstract：:RNA-dependent protein kinase PKR is an important regulator of gene expression in interferon (IFN)-treated and virus-infected cells. The 50-kb gene encoding human PKR kinase (pkr) is inducible by IFN. Transfection analyses, using chloramphenicol acetyltransferase (CAT) as the reporter in constructs possessing various 5...

journal_title：Journal of virology

authors： Kuhen KL,Vessey JW,Samuel CE

更新日期：1998-12-01 00:00:00

abstract：UNLABELLED:Herpes simplex virus 1 (HSV-1) most commonly causes recrudescent labial ulcers; however, it is also the leading cause of infectious blindness in developed countries. Previous research in animal models has demonstrated that the severity of HSV-1 ocular disease is influenced by three main factors: host innate ...

journal_title：Journal of virology

authors： Lee K,Kolb AW,Larsen I,Craven M,Brandt CR

更新日期：2016-08-26 00:00:00

abstract：:We have demonstrated that intracellular forms of NOTCH1 transactivate two major Epstein-Barr virus (EBV) latent promoters, the LMP1 and Cp1 promoters in an EBV-negative B-cell line, BJAB. Truncated intracellular NOTCH1 associated with the nuclear membrane (DeltaE) transactivates the LMP1 promoter fivefold; however, th...

journal_title：Journal of virology

authors： Cotter M,Callahan J,Aster J,Robertson E

更新日期：2000-02-01 00:00:00

abstract：:Recombination studies have established that retroviral long terminal repeats (LTRs) are important genetic determinants of the viral capacity to induce hematopoietic tumors and to specify the type of cell making up the tumor. Plasmids containing LTRs of several murine leukemia viruses linked to the chloramphenicol acet...

journal_title：Journal of virology

authors： Short MK,Okenquist SA,Lenz J

更新日期：1987-04-01 00:00:00

abstract：:Broadly neutralizing antibodies (bNAbs) are being explored for HIV-1 prevention and cure strategies. However, administration of purified bNAbs poses challenges in resource-poor settings, where the HIV-1 disease burden is greatest. In vivo vector-based production of bNAbs represents an alternative strategy. We investig...

journal_title：Journal of virology

authors： Badamchi-Zadeh A,Tartaglia LJ,Abbink P,Bricault CA,Liu PT,Boyd M,Kirilova M,Mercado NB,Nanayakkara OS,Vrbanac VD,Tager AM,Larocca RA,Seaman MS,Barouch DH

更新日期：2018-03-14 00:00:00