Antigens of Pichinde virus I. Relationship of soluble antigens derived from infected BHK-21 cells to the structural components of the virion.

abstract：:Bovine spongiform encephalopathy (BSE) is a fatal, transmissible, neurodegenerative disease of cattle. BSE can be transmitted experimentally between cattle through the oral route, and in this study, brain tissue samples from animals at different time points postinoculation were analyzed for changes in gene expression....

journal_title：Journal of virology

authors： Tang Y,Xiang W,Hawkins SA,Kretzschmar HA,Windl O

更新日期：2009-09-01 00:00:00

abstract：:We established a novel experimental model for human T-cell leukemia virus type 1 (HTLV-1)-induced tumor using NOD-SCID/gammac(null) (NOG) mice. This model is very useful for investigating the mechanism of tumorigenesis and malignant cell growth of adult T-cell leukemia (ATL)/lymphoma, which still remains unclear. Nine...

journal_title：Journal of virology

authors： Dewan MZ,Terashima K,Taruishi M,Hasegawa H,Ito M,Tanaka Y,Mori N,Sata T,Koyanagi Y,Maeda M,Kubuki Y,Okayama A,Fujii M,Yamamoto N

更新日期：2003-05-01 00:00:00

abstract：:Infectious hematopoietic necrosis virus (IHNV) is a rhabdovirus that produces an acute, lethal infection in rainbow trout (Oncorhynchus mykiss). Fish that survive infection cease to produce detectable infectious virus at approximately 46 days after infection, yet there is evidence that survivor fish continue to harbor...

journal_title：Journal of virology

authors： Kim CH,Dummer DM,Chiou PP,Leong JA

更新日期：1999-01-01 00:00:00

abstract：:While the facile transmission of chronic wasting disease (CWD) remains incompletely elucidated, studies in rodents suggest that exposure of the respiratory mucosa may be an efficient pathway. The present study was designed to address this question in the native cervid host. Here, we demonstrate aerosol transmission of...

journal_title：Journal of virology

authors： Denkers ND,Hayes-Klug J,Anderson KR,Seelig DM,Haley NJ,Dahmes SJ,Osborn DA,Miller KV,Warren RJ,Mathiason CK,Hoover EA

更新日期：2013-02-01 00:00:00

abstract：:West Nile virus (WNV) is a neurotropic mosquito-borne flavivirus of global importance. Neuroinvasive WNV infection results in encephalitis and can lead to prolonged neurological impairment or death. Type I interferon (IFN-I) is crucial for promoting antiviral defenses through the induction of antiviral effectors, whic...

journal_title：Journal of virology

authors： O'Neal JT,Upadhyay AA,Wolabaugh A,Patel NB,Bosinger SE,Suthar MS

更新日期：2019-03-05 00:00:00

abstract：:cis-Acting elements in the viral genome RNA (vRNA) are essential for the translation, replication, and/or encapsidation of RNA viruses. In this study, a novel conserved cis-acting element was identified in the capsid-coding region of mosquito-borne flavivirus. The downstream of 5' cyclization sequence (5'CS) pseudokno...

journal_title：Journal of virology

authors： Liu ZY,Li XF,Jiang T,Deng YQ,Zhao H,Wang HJ,Ye Q,Zhu SY,Qiu Y,Zhou X,Qin ED,Qin CF

更新日期：2013-06-01 00:00:00

abstract：:Proliferative cell nuclear antigen (PCNA), a conserved plant protein as well as an important replication factor, is induced in response to geminivirus infection in the resting cells of the phloem tissues. The biochemical role of PCNA in rolling circle replication (RCR) of geminivirus DNA has not been explored in detai...

journal_title：Journal of virology

authors： Bagewadi B,Chen S,Lal SK,Choudhury NR,Mukherjee SK

更新日期：2004-11-01 00:00:00

abstract：:A strategy involving polymerase chain reaction amplification of cDNAs was designed to study the expression of the hamster polyomavirus (HaPV) early region in HaPV-transformed rat fibroblasts, productively HaPV-infected cells, and HaPV-induced lymphoma. We identified three mRNAs resulting from alternative splicing of o...

journal_title：Journal of virology

authors： Goutebroze L,Feunteun J

更新日期：1992-04-01 00:00:00

abstract：:YY1 is a zinc finger transcription factor which acts as either a repressor or an activator dependent on the promoter context. YY1 is a potent activator of the genuine human papillomavirus type 18 (HPV-18) upstream regulatory region (URR) in HeLa cells, which are known for high-level expression of the HPV-18 early gene...

journal_title：Journal of virology

authors： Bauknecht T,Jundt F,Herr I,Oehler T,Delius H,Shi Y,Angel P,Zur Hausen H

更新日期：1995-01-01 00:00:00

abstract：:Merkel cell carcinoma (MCC) is the most aggressive skin cancer. Recently, it was demonstrated that human Merkel cell polyomavirus (MCV) is clonally integrated in approximately 80% of MCC tumors. However, direct evidence for whether oncogenic viral proteins are needed for the maintenance of MCC cells is still missing. ...

journal_title：Journal of virology

authors： Houben R,Shuda M,Weinkam R,Schrama D,Feng H,Chang Y,Moore PS,Becker JC

更新日期：2010-07-01 00:00:00

abstract：UNLABELLED:Susceptibility or resistance to prion infection in humans and animals depends on single prion protein (PrP) amino acid substitutions in the host, but the agent's modulating role has not been well investigated. Compared to disease incubation times in wild-type homozygous ARQ/ARQ (where each triplet represents...

journal_title：Journal of virology

authors： Langeveld JP,Jacobs JG,Hunter N,van Keulen LJ,Lantier F,van Zijderveld FG,Bossers A

更新日期：2015-10-28 00:00:00

abstract：:Differentiating infected from vaccinated animals (DIVA) strategies have been central enabling techniques in several successful viral disease elimination programs. However, owing to their long and uncertain development process, no DIVA-compatible vaccines are available for many important diseases. We report herein a ne...

journal_title：Journal of virology

authors： Xue Q,Xu H,Liu H,Pan J,Yang J,Sun M,Chen Y,Xu W,Cai X,Ma H

更新日期：2020-02-28 00:00:00

abstract：:Retroviral capsid assembly can occur by either of two distinct morphogenic processes: in type C viruses, the capsid assembles and buds at the plasma membrane, while in type B and D viruses, the capsid assembles within the cytoplasm and is then transported to the plasma membrane for budding. We have previously reported...

journal_title：Journal of virology

authors： Choi G,Park S,Choi B,Hong S,Lee J,Hunter E,Rhee SS

更新日期：1999-07-01 00:00:00

abstract：:We have presented a new approach to studying bacteriophage T4 head maturation. Using a modified M-band technique, we have shown that progeny deoxyribonucleic acid (DNA) was synthesized on the host cell membrane throughout infection. This DNA was released from the membrane later in infection as the result of formation ...

journal_title：Journal of virology

authors： Siegel PJ,Schaechter M

更新日期：1973-03-01 00:00:00

abstract：:Several members of the APOBEC3 DNA cytosine deaminase family can potently inhibit Vif-deficient human immunodeficiency virus type 1 (HIV-1) by catalyzing cytosine deamination in viral cDNA and impeding reverse transcription. HIV-1 counteracts restriction with the virally encoded Vif protein, which targets relevant APO...

journal_title：Journal of virology

authors： Wang J,Shaban NM,Land AM,Brown WL,Harris RS

更新日期：2018-05-29 00:00:00

abstract：:Among the members of the paramyxovirus family, the transcription process and the components involved have been studied under in vitro conditions thus far. Here, we reexamined the function of the viral RNA-dependent RNA polymerase through infection studies with Sendai virus (SeV) N and P deletion (Delta) mutants. To el...

journal_title：Journal of virology

authors： Wiegand MA,Bossow S,Schlecht S,Neubert WJ

更新日期：2007-12-01 00:00:00

abstract：:Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia/lymphoma and is associated with a variety of immunoregulatory disorders. HTLV-1 has been shown to bind to and infect a variety of hematopoietic and nonhematopoietic cells. However, both in vivo and in vitro, the provirus is mos...

journal_title：Journal of virology

authors： Newbound GC,Andrews JM,O'Rourke JP,Brady JN,Lairmore MD

更新日期：1996-04-01 00:00:00

abstract：:Primary HIV-1 infection (PHI) is marked by a flu-like syndrome and high levels of viremia that decrease to a viral set point with the first emergence of virus-specific CD8+ T-cell responses. Here, we investigated in a large cohort of 527 subjects the immunodominance pattern of the first virus-specific cytotoxic T-lymp...

journal_title：Journal of virology

authors： Streeck H,Jolin JS,Qi Y,Yassine-Diab B,Johnson RC,Kwon DS,Addo MM,Brumme C,Routy JP,Little S,Jessen HK,Kelleher AD,Hecht FM,Sekaly RP,Rosenberg ES,Walker BD,Carrington M,Altfeld M

更新日期：2009-08-01 00:00:00

abstract：:Walleye dermal sarcoma virus (WDSV) is a complex retrovirus associated with dermal sarcomas in walleye fish. A WDSV accessory gene encodes a cyclin homolog or retroviral cyclin (rv-cyclin). WDSV rv-cyclin was found to be associated with transcription complexes and to affect transcription in a cell-type and promoter-de...

journal_title：Journal of virology

authors： Rovnak J,Quackenbush SL

更新日期：2006-12-01 00:00:00

abstract：:Cloned DNA from the P155 mutant of polyoma virus transforms cells in culture as efficiently as wild-type DNA, but has a much lower tumorigenic potential when injected into newborn rats. Like cells transformed by wild-type DNA, cells transformed by the mutant DNA grow in low serum concentrations, form colonies in agar ...

journal_title：Journal of virology

authors： Gelinas C,Chartrand P,Bastin M

更新日期：1982-09-01 00:00:00

abstract：:All positive-strand RNA viruses reorganize host intracellular membranes to assemble their replication complexes. Similarly, brome mosaic virus (BMV) induces two alternate forms of membrane-bound RNA replication complexes: vesicular spherules and stacks of appressed double-membrane layers. The mechanisms by which these...

journal_title：Journal of virology

authors： Zhang J,Diaz A,Mao L,Ahlquist P,Wang X

更新日期：2012-05-01 00:00:00

abstract：:Lipid biosynthesis was measured in cultured chicken embryo cells after infection with fowlpox virus. Between 24 and 72 h postinfection, fowlpox virus-infected cells incorporated less [14C]acetate and 3H2O into fatty acids and sterols than did mock-infected cells, demonstrating a virus-dependent inhibition of general l...

journal_title：Journal of virology

authors： Buttke TM,Gafford LG

更新日期：1982-08-01 00:00:00

abstract：:To investigate the relation between the polyoma tumor-specific transplantation antigen and the virus-coded proteins, mice were immunized by inoculation of a variety of viable polyoma virus mutants and then challenged with polyoma virus-induced tumors. Two classes of early region mutants were used. One class produces a...

journal_title：Journal of virology

authors： Dalianis T,Magnusson G,Ito Y,Klein G

更新日期：1982-09-01 00:00:00

abstract：:Hepatitis E virus (HEV) is a common cause of acute viral hepatitis worldwide. Most HEV infections are asymptomatic, but immunocompromised patients infected with HEV genotype 3 (HEV3), HEV4, or HEV7 may develop chronic infections. The HEV particles in stools are naked (nHEV), while those in the serum and culture supern...

journal_title：Journal of virology

authors： Capelli N,Marion O,Dubois M,Allart S,Bertrand-Michel J,Lhomme S,Abravanel F,Izopet J,Chapuy-Regaud S

更新日期：2019-02-05 00:00:00

abstract：:The major histocompatibility complex (MHC) class I region of humans, chimpanzees (Pan troglodytes), and bonobos (Pan paniscus) is highly similar, and orthologues of HLA-A, -B, and -C are present in both Pan species. Based on functional characteristics, the different HLA-A allotypes are classified into different supert...

journal_title：Journal of virology

authors： de Groot NG,Heijmans CMC,de Ru AH,Otting N,Koning F,van Veelen PA,Bontrop RE

更新日期：2020-04-16 00:00:00

abstract：:TNPO3 is a nuclear importer required for HIV-1 infection. Here, we show that depletion of TNPO3 leads to an HIV-1 block after nuclear import but prior to integration. To investigate the mechanistic requirement of TNPO3 in HIV-1 infection, we tested the binding of TNPO3 to the HIV-1 core and found that TNPO3 binds to t...

journal_title：Journal of virology

authors： Valle-Casuso JC,Di Nunzio F,Yang Y,Reszka N,Lienlaf M,Arhel N,Perez P,Brass AL,Diaz-Griffero F

更新日期：2012-05-01 00:00:00

abstract：:Transcription of herpesviral late genes is stimulated after the onset of viral DNA replication but otherwise restricted. Late gene expression in gammaherpesviruses requires the coordination of six early viral proteins, termed viral transactivation factors (vTFs). Here, we mapped the organization of this protein comple...

journal_title：Journal of virology

authors： Davis ZH,Hesser CR,Park J,Glaunsinger BA

更新日期：2015-10-14 00:00:00

abstract：:Replicase gene expression by the human coronavirus 229E involves the synthesis of two large polyproteins, pp1a and pp1ab. Experimental evidence suggests that these precursor molecules are subject to extensive proteolytic processing. In this study, we show that a chymotrypsin-like enzyme, the virus-encoded 3C-like prot...

journal_title：Journal of virology

authors： Ziebuhr J,Siddell SG

更新日期：1999-01-01 00:00:00

abstract：:Live attenuated human immunodeficiency virus type 1 (HIV-1) vaccines are considered unsafe because faster-replicating pathogenic virus variants may evolve after vaccination. We previously presented a conditional-live HIV-1 variant of which replication can be switched off as an alternative vaccination strategy. To impr...

journal_title：Journal of virology

authors： Das AT,Baldwin CE,Vink M,Berkhout B

更新日期：2005-03-01 00:00:00

abstract：:The cell surface receptor T cell immunoglobulin mucin domain 1 (TIM-1) dramatically enhances filovirus infection of epithelial cells. Here, we showed that key phosphatidylserine (PtdSer) binding residues of the TIM-1 IgV domain are critical for Ebola virus (EBOV) entry through direct interaction with PtdSer on the vir...

journal_title：Journal of virology

authors： Moller-Tank S,Kondratowicz AS,Davey RA,Rennert PD,Maury W

更新日期：2013-08-01 00:00:00