当前位置： SCI文献检索 > VACCINE期刊下所有文献 > A method for evaluating and comparing immunisation schedules that cover multiple diseases: Illustrative application to the UK routine childhood vaccine schedule.

A method for evaluating and comparing immunisation schedules that cover multiple diseases: Illustrative application to the UK routine childhood vaccine schedule.

Abstract：

BACKGROUND:In the UK, the childhood immunisation programme is given in the first 5 years of life and protects against 12 vaccine-preventable diseases. Recently, this programme has undergone changes with addition of vaccination against Meningitis B from September 2015 and the removal of the primary dose of protection against Meningitis C from July 2016. These hanges have direct impact on the associated diseases but in addition may induce indirect effects on the vaccines that are given simultaneously or later in the programme. In this work, we developed a novel formal method to evaluate the impact of vaccination changes to one aspect of the programme across an entire vaccine programme. METHODS:Firstly, we combined transmission modelling (for four diseases) and historic data synthesis (for eight diseases) to project, for each disease, the disease burden at different levels of effective coverage against the associated disease. Secondly, we used a simulation model to determine the vector of effective coverage against each disease under three variations of the current childhood schedule. Combining these, we calculated the vector of disease burden across the programme under different scenarios, and assessed the direct and indirect effects of the schedule changes. RESULTS:Through illustrative application of our novel framework to three scenarios of the current childhood immunisation programme in the UK, we demonstrated the feasibility of this unifying approach. For each disease in the programme, we successfully quantified the residual disease burden due to the change. For some diseases, the change was indirectly beneficial and reduced the burden, whereas for others the effect was adverse and the change increased the disease burden. CONCLUSIONS:Our results demonstrate the potential benefit of considering the programme-wide impact of changes to an immunisation schedule, and our framework is an important step in the development of a means for systematically doing so.

journal_name

Vaccine

journal_title

Vaccine

authors

Panovska-Griffiths J,Crowe S,Pagel C,Shiri T,Grove P,Utley M

doi

10.1016/j.vaccine.2018.05.083

subject

Has Abstract

pub_date

2018-08-23 00:00:00

pages

5340-5347

issue

35

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(18)30749-7

journal_volume

36

pub_type

杂志文章

相关文献

VACCINE文献大全
  • Understanding vaccination resistance: vaccine search term selection bias and the valence of retrieved information.

    abstract：CONTEXT:Dubious vaccination-related information on the Internet leads some parents to opt out of vaccinating their children. OBJECTIVES:To determine if negative, neutral and positive search terms retrieve vaccination information that differs in valence and confirms searchers' assumptions about vaccination. METHODS:A ...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2014.08.042

    authors： Ruiz JB,Bell RA

    更新日期：2014-10-07 00:00:00

  • Low mortality after mild measles infection compared to uninfected children in rural West Africa.

    abstract：BACKGROUND:It has been assumed that measles infection may be associated with persistent immune suppression and long-term excess mortality. However, few community studies of mortality after measles infection have been carried out. We examined long-term mortality for measles cases, sub-clinical measles cases, and uninfec...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/s0264-410x(02)00430-9

    authors： Aaby P,Simondon F,Samb B,Cisse B,Jensen H,Lisse IM,Soumaré M,Whittle H

    更新日期：2002-11-22 00:00:00

  • Study of live recombinant cold-adapted influenza bivalent vaccine of type A for use in children: an epidemiological control trial.

    abstract：:Live cold-adapted recombinant bivalent vaccine of influenza type A was studied in a controlled field trial in 1982-1983 among nearly 30,000 children 3-15 years old. The bivalent vaccine consisted of recombinants 47/25/1 (H1N1) and 47/7/2 (H3N2) of wild-type viruses A/Brazil/11/78 (H1N1) and A/Bangkok/1/79 (H3N2) with ...

    journal_title：Vaccine

    pub_type： 临床试验,杂志文章

    doi：10.1016/0264-410x(86)90049-6

    authors： Alexandrova GI,Budilovsky GN,Koval TA,Polezhaev FI,Garmashova LM,Ghendon YuZ,Romanova YR,Smorodintsev AA

    更新日期：1986-06-01 00:00:00

  • Guidance on the evaluation of Plasmodium vivax vaccines in populations exposed to natural infection.

    abstract：:In this paper we give guidance for the design and conduct of vaccine trials against Plasmodium vivax malaria. The paper supplements earlier guidelines on the planning of vaccine trials against Plasmodium falciparum malaria [WHO. Guidelines for the evaluation of Plasmodium falciparum vaccines in populations exposed to ...

    journal_title：Vaccine

    pub_type： 杂志文章,实务指引,评审

    doi：10.1016/j.vaccine.2009.07.018

    authors： Mueller I,Moorthy VS,Brown GV,Smith PG,Alonso P,Genton B,WHO Malaria Vaccine Advisory Committee (MALVAC).

    更新日期：2009-09-18 00:00:00

  • Semantic network analysis of vaccine sentiment in online social media.

    abstract：OBJECTIVE:To examine current vaccine sentiment on social media by constructing and analyzing semantic networks of vaccine information from highly shared websites of Twitter users in the United States; and to assist public health communication of vaccines. BACKGROUND:Vaccine hesitancy continues to contribute to subopti...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2017.05.052

    authors： Kang GJ,Ewing-Nelson SR,Mackey L,Schlitt JT,Marathe A,Abbas KM,Swarup S

    更新日期：2017-06-22 00:00:00

  • Packaging limits and stability of HIV-1 sequences in a coxsackievirus B vector.

    abstract：:Enteroviruses elicit protective mucosal immune responses that could be harnessed as part of a strategy to prevent sexual transmission of the human immunodeficiency virus-1 (HIV-1). We report the construction of replication-competent recombinant vectors of coxsackievirus B3 (CVB3) that express one or more portions of t...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2009.04.035

    authors： Miller JP,Geng Y,Ng HL,Yang OO,Krogstad P

    更新日期：2009-06-19 00:00:00

  • The site of administration influences both the type and the magnitude of the immune response induced by DNA vaccine electroporation.

    abstract：:We investigated the influence of the site of administration of DNA vaccine on the induced immune response. DNA vaccines were administered by electroporation at three different sites: tibial cranial muscle, abdominal skin and ear pinna. Aiming to draw general conclusions about DNA vaccine delivery, we successively used...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2015.05.005

    authors： Vandermeulen G,Vanvarenberg K,De Beuckelaer A,De Koker S,Lambricht L,Uyttenhove C,Reschner A,Vanderplasschen A,Grooten J,Préat V

    更新日期：2015-06-22 00:00:00

  • Safety, immunogenicity, and kinetics of the immune response to a single dose of virosome-formulated hepatitis A vaccine in Thais.

    abstract：:The safety and immunogenicity of a single dose of virosome-formulated hepatitis A vaccine was evaluated in healthy seronegative Thai volunteers. Immunization elicited primarily mild transient reactions which did not interfere with normal activities. All subjects possessed > 20 mIU of anti-hepatitis A virus antibody pe...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/0264-410x(95)00007-n

    authors： Poovorawan Y,Theamboonlers A,Chumdermpadetsuk S,Glück R,Cryz SJ Jr

    更新日期：1995-07-01 00:00:00

  • Combined vaccination against yellow fever and typhoid fever: a comparative trial.

    abstract：:In order to evaluate a combination of yellow fever and typhoid fever vaccine, we conducted a controlled trial comparing reactogenicity and immunogenicity of Vi polysaccharide (ViPS) vaccine and yellow fever 17D (YF) vaccine after single, simultaneous and combined administration. The combined YF/ViPS vaccine was prepar...

    journal_title：Vaccine

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0264-410x(94)90267-4

    authors： Ambrosch F,Fritzell B,Gregor J,Jonas S,Kollaritsch H,Teulieres L,Wiedermann G

    更新日期：1994-05-01 00:00:00

  • Safety of Russian-backbone seasonal trivalent, live-attenuated influenza vaccine in a phase II randomized placebo-controlled clinical trial among children in urban Bangladesh.

    abstract：INTRODUCTION:Live-attenuated influenza vaccines (LAIVs) have the potential to be affordable, effective, and logistically feasible for immunization of children in low-resource settings. MATERIAL AND METHODS:We conducted a phase II, randomized, double-blind, parallel group, placebo-controlled trial on the safety of the ...

    journal_title：Vaccine

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.vaccine.2015.04.048

    authors： Ortiz JR,Goswami D,Lewis KD,Sharmeen AT,Ahmed M,Rahman M,Rahman MZ,Feser J,Neuzil KM,Brooks WA

    更新日期：2015-06-26 00:00:00

  • Oral immunization with recombinant BCG induces cellular and humoral immune responses against the foreign antigen.

    abstract：:It has been shown recently that BCG can be used as a live recombinant vaccine to stimulate immune responses. Proliferative or cytotoxic T-cell responses against several viral proteins such as HIV Gag, Env or Nef were obtained after parenteral immunization with BCG expressing these proteins. Antibody responses were als...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/0264-410x(93)90096-g

    authors： Lagranderie M,Murray A,Gicquel B,Leclerc C,Gheorghiu M

    更新日期：1993-10-01 00:00:00

  • A short report on the highlights of world-wide development of RIX4414: a North American experience comparative evaluation of safety and immunogenicity of two dosages of an oral live attenuated human rotavirus vaccine (RIX4414) in infants in the United Sta

    abstract：:This randomized, double-blind trial conducted in the US and Canada was conducted to compare the safety and immunogenicity of two dosages of live attenuated oral monovalent G1 human rotavirus (HRV) vaccine administered orally at a 2-month interval concomitantly with routine childhood vaccines to healthy infants 5-15 we...

    journal_title：Vaccine

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.vaccine.2005.07.030

    authors： Dennehy PH,North American Human Rotavirus Vaccine Study Group.

    更新日期：2006-05-01 00:00:00

  • Effect of different adjuvant formulations on the immunogenicity and protective effect of a live Mycoplasma hyopneumoniae vaccine after intramuscular inoculation.

    abstract：:Mycoplasma hyopneumoniae (M. hyopneumoniae) vaccine strain 168 is an intrapulmonically injected attenuated live vaccine that is available in the Chinese market. The aim of this study was to develop suitable adjuvants for this live vaccine to provide effective protection after intramuscular inoculation. Several adjuvan...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2014.03.071

    authors： Xiong Q,Wei Y,Xie H,Feng Z,Gan Y,Wang C,Liu M,Bai F,Xie F,Shao G

    更新日期：2014-06-05 00:00:00

  • Vaccination with a preparation based on recombinant cysteine peptidases and canine IL-12 does not protect dogs from infection with Leishmania infantum.

    abstract：:Cysteine peptidases (CPs) have been implicated in various processes central to the pathogenicity of Leishmania parasites, and are thought to be key factors in the host-parasite interaction. In order to fully evaluate the potential of the CPs as vaccine candidates, studies in natural host species are required. In the s...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2005.12.039

    authors： Poot J,Spreeuwenberg K,Sanderson SJ,Schijns VE,Mottram JC,Coombs GH,Vermeulen AN

    更新日期：2006-03-24 00:00:00

  • Development and evaluation of live attenuated Salmonella vaccines in newly hatched duckings.

    abstract：:Domestic ducks remain a major source of zoonotic Salmonella enterica infections for man worldwide and approaches to protection should include vaccine-mediated immunity. With this in mind we developed several genetically defined mutants in a virulent duck Salmonella typhimurium isolate TT-1. From initial tests for viru...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2015.09.004

    authors： Tang T,Gao Q,Barrow P,Wang M,Cheng A,Jia R,Zhu D,Chen S,Liu M,Sun K,Yang Q,Chen X

    更新日期：2015-10-13 00:00:00

  • Prospects for oral replicating adenovirus-vectored vaccines.

    abstract：:Orally delivered replicating adenovirus (Ad) vaccines have been used for decades to prevent adenovirus serotype 4 and 7 respiratory illness in military recruits, demonstrating exemplary safety and high efficacy. That experience suggests that oral administration of live recombinant Ads (rAds) holds promise for immuniza...

    journal_title：Vaccine

    pub_type： 杂志文章,评审

    doi：10.1016/j.vaccine.2013.05.016

    authors： Deal C,Pekosz A,Ketner G

    更新日期：2013-07-11 00:00:00

  • One size does not fit all: The impact of primary vaccine container size on vaccine distribution and delivery.

    abstract：BACKGROUND:While the size and type of a vaccine container (i.e., primary container) can have many implications on the safety and convenience of a vaccination session, another important but potentially overlooked consideration is how the design of the primary container may affect the distribution of the vaccine, its res...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2015.04.018

    authors： Haidari LA,Wahl B,Brown ST,Privor-Dumm L,Wallman-Stokes C,Gorham K,Connor DL,Wateska AR,Schreiber B,Dicko H,Jaillard P,Avella M,Lee BY

    更新日期：2015-06-22 00:00:00

  • Zika virus knowledge, attitudes, and vaccine interest among university students.

    abstract：BACKGROUND:Zika virus vaccine development is underway. We examined interest in receiving a Zika virus vaccine (after one becomes commercially available) among students at a large public university in Northern Virginia. METHODS:An online survey of Zika virus-related knowledge, attitudes, and interest in receiving a Zik...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2016.12.050

    authors： Painter JE,Plaster AN,Tjersland DH,Jacobsen KH

    更新日期：2017-02-07 00:00:00

  • Genetic fusion of proteins to the SIV Tat protein enhances their immunogenicity.

    abstract：:The potential of genetically fusing recombinant proteins to the simian immunodeficiency virus (SIV) Tat protein has been investigated. The recombinant SIV Tat protein was initially expressed in very low amounts in E. coli, but optimization of the coding sequence for translation in the bacterial host significantly impr...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2005.09.012

    authors： Chen YH,Diassiti A,Randall RE

    更新日期：2006-02-06 00:00:00

  • Fish soluble Toll-like receptor (TLR)5 amplifies human TLR5 response via physical binding to flagellin.

    abstract：:Fish has a soluble form of TLR5 ortholog (TLR5S), which does not exist in mammals. We identified TLR5S from rainbow trout and named rtTLR5S, which was about 38% homologous to the extracellular domains of human (hu) and mouse TLR5. Adjuvancy of rtTLR5S to flagellin response by human TLR5 (huTLR5) was tested in this stu...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2005.11.003

    authors： Tsujita T,Ishii A,Tsukada H,Matsumoto M,Che FS,Seya T

    更新日期：2006-03-15 00:00:00

  • Purification of O-specific polysaccharide from lipopolysaccharide produced by Salmonella enterica serovar Paratyphi A.

    abstract：:The O specific polysaccharide (OSP) of the lipopolysaccharide (LPS) of Salmonella enterica serovar Paratyphi A is a protective antigen and the target for vaccine development. LPS is the major constituent of the outer membrane of S. Paratyphi A with the OSP exposed on the surface, in addition to the cell associated LPS...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2014.02.090

    authors： Kothari S,Kim JA,Kothari N,Jones C,Choe WS,Carbis R

    更新日期：2014-05-01 00:00:00

  • Case-based surveillance enhanced with measles virus detection/genotyping is essential to maintain measles elimination in Aichi Prefecture, Japan.

    abstract：BACKGROUND:Japan was verified as having achieved measles elimination by the Measles Regional Verification Commission in the Western Pacific Region in March 2015. Verification of measles elimination implies the absence of continuous endemic transmission. After the last epidemic in 2007 with an estimated 18,000 cases, Ja...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2015.08.070

    authors： Minagawa H,Yasui Y,Adachi H,Ito M,Hirose E,Nakamura N,Hata M,Kobayashi S,Yamashita T

    更新日期：2015-11-09 00:00:00

  • Incidence of severe Plasmodium falciparum malaria as a primary endpoint for vaccine efficacy trials in Bandiagara, Mali.

    abstract：:Potential endpoints for blood stage malaria vaccine efficacy trials include uncomplicated malaria disease, which is hard to differentiate from other febrile illnesses, and mortality, which requires prohibitively large sample sizes. Strictly defined severe malaria predicts malaria-associated mortality where case fatali...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2004.01.054

    authors： Lyke KE,Dicko A,Kone A,Coulibaly D,Guindo A,Cissoko Y,Traoré K,Plowe CV,Doumbo OK

    更新日期：2004-08-13 00:00:00

  • Effectiveness of Jeryl Lynn-containing vaccine in Spanish children.

    abstract：:We evaluated the effectiveness of the Jeryl Lynn strain vaccine in a large outbreak of mumps in Navarre, Spain, 2006-2008. Each of the 241 cases of mumps occurring in children over 15 months of age born between 1998 and 2005 was compared with 5 controls individually matched by sex, birth date, district of residence an...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2009.02.001

    authors： Castilla J,García Cenoz M,Arriazu M,Fernández-Alonso M,Martínez-Artola V,Etxeberria J,Irisarri F,Barricarte A

    更新日期：2009-03-26 00:00:00

  • Comparison of adjuvants to optimize influenza neutralizing antibody responses.

    abstract：:Seasonal influenza vaccines represent a positive intervention to limit the spread of the virus and protect public health. Yet continual influenza evolution and its ability to evade immunity pose a constant threat. For these reasons, vaccines with improved potency and breadth of protection remain an important need. We ...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2019.08.030

    authors： Rudicell RS,Garinot M,Kanekiyo M,Kamp HD,Swanson K,Chou TH,Dai S,Bedel O,Simard D,Gillespie RA,Yang K,Reardon M,Avila LZ,Besev M,Dhal PK,Dharanipragada R,Zheng L,Duan X,Dinapoli J,Vogel TU,Kleanthous H,Mascola J

    更新日期：2019-09-30 00:00:00

  • Priority allocation of pandemic influenza vaccines in Australia - Recommendations of 3 community juries.

    abstract：BACKGROUND:Pandemic planning has historically been oriented to respond to an influenza virus, with vaccination strategy being a key focus. As the current COVID-19 pandemic plays out, the Australian government is closely monitoring progress towards development of SARS-CoV2 vaccines as a definitive intervention. However,...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2020.12.010

    authors： Degeling C,Williams J,Carter SM,Moss R,Massey P,Gilbert GL,Shih P,Braunack-Mayer A,Crooks K,Brown D,McVernon J

    更新日期：2021-01-08 00:00:00

  • Circulating cellular immune response to oral immunization of humans with cholera toxin B-subunit.

    abstract：:Peripheral blood mononuclear cells were taken from subjects before and after oral immunization with cholera toxin B-subunit. Cells obtained from naive volunteers before immunization did not proliferate in vitro to B-subunit. Oral immunization induced a proliferative response in all volunteers with a peak stimulation i...

    journal_title：Vaccine

    pub_type： 临床试验,杂志文章

    doi：10.1016/0264-410x(93)90005-i

    authors： Lewis DJ,Castello-Branco LR,Novotny P,Dougan G,Poulton TA,Griffin GE

    更新日期：1993-01-01 00:00:00

  • Complete protection against lethal challenge of novel H7N9 virus with heterologous inactivated H7 vaccine in mice.

    abstract：:A prototype H7 influenza vaccine constructed based on the H7N7 outbreak in 2003 was tested for the protective efficacy against the novel H7N9 virus in a lethal murine challenge model. Serum samples from vaccinated mice showed significant neutralizing activity against the H7N9 virus and the mice were completely protect...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2014.07.087

    authors： Tang LH,Lim JH,Kuah LF,Lau YF

    更新日期：2014-09-22 00:00:00

  • Intranasal c-di-GMP-adjuvanted plant-derived H5 influenza vaccine induces multifunctional Th1 CD4+ cells and strong mucosal and systemic antibody responses in mice.

    abstract：:Vaccination is the best available measure of limiting the impact of the next influenza pandemic. Ideally, a candidate pandemic influenza vaccine should be easy to administer and should elicit strong mucosal and systemic immune responses. Production of influenza subunit antigen in transient plant expression systems is ...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2011.04.094

    authors： Madhun AS,Haaheim LR,Nøstbakken JK,Ebensen T,Chichester J,Yusibov V,Guzman CA,Cox RJ

    更新日期：2011-07-12 00:00:00

  • Evaluation of 238 antigens of Leptospira borgpetersenii serovar Hardjo for protection against kidney colonisation.

    abstract：:Leptospirosis is a zoonotic disease affecting animals and humans worldwide. Leptospiral infection in cattle can cause reproductive failure and reduced weight gain, and importantly, infection represents a significant disease risk for farmers. Current bacterin vaccines offer protection that is short-lived and restricted...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2012.11.028

    authors： Murray GL,Lo M,Bulach DM,Srikram A,Seemann T,Quinsey NS,Sermswan RW,Allen A,Adler B

    更新日期：2013-01-07 00:00:00