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Safety, immunogenicity, and kinetics of the immune response to a single dose of virosome-formulated hepatitis A vaccine in Thais.

Abstract：

:The safety and immunogenicity of a single dose of virosome-formulated hepatitis A vaccine was evaluated in healthy seronegative Thai volunteers. Immunization elicited primarily mild transient reactions which did not interfere with normal activities. All subjects possessed > 20 mIU of anti-hepatitis A virus antibody per ml of serum one month after immunization. Such a prolonged rise in antibody titre is characteristic of virosome-formulated vaccines. Protective titres (> 20 mIU ml-1) were maintained by all subjects over the one-year observation period.

journal_name

Vaccine

journal_title

Vaccine

authors

Poovorawan Y,Theamboonlers A,Chumdermpadetsuk S,Glück R,Cryz SJ Jr

doi

10.1016/0264-410x(95)00007-n

subject

Has Abstract

pub_date

1995-07-01 00:00:00

pages

891-3

issue

10

eissn

0264-410X

issn

1873-2518

pii

0264410X9500007N

journal_volume

13

pub_type

杂志文章

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