Fish soluble Toll-like receptor (TLR)5 amplifies human TLR5 response via physical binding to flagellin.

abstract：:In case of a bite by a rabies infected animal, the World Health Organisation recommends a prophylactic treatment including the administration of Human Rabies Immunoglobulins (HRIGs) or highly purified F(ab')2 fragments produced from Equine Rabies Immunoglobulin (F(ab')2 - ERIGs). According to international regulation,...

journal_title：Vaccine

authors： Korimbocus J,Dehay N,Tordo N,Cano F,Morgeaux S

更新日期：2016-06-14 00:00:00

abstract：OBJECTIVE:Implementing national-level vaccination programs involves long-term investment, which can be a significant financial burden, particularly in resource-limited settings. Although many studies have assessed the economic impacts of providing vaccinations, evidence on the positive and negative implications of huma...

journal_title：Vaccine

authors： Chootipongchaivat S,Chantarastapornchit V,Kulpeng W,Ceria JA,Tolentino NI,Teerawattananon Y

更新日期：2016-09-14 00:00:00

abstract：:Our initial results with a bovine papilloma virus (BPV) vector expression system indicated that we could produce significant amounts of Epstein-Barr virus (EBV) gp340/220 in the supernatant of a mouse fibroblast cell line. We have now extended these findings to show that the truncated version of gp340/220, where the m...

journal_title：Vaccine

authors： Madej M,Conway MJ,Morgan AJ,Sweet J,Wallace L,Qualtiere LF,Arrand JR,Mackett M

更新日期：1992-01-01 00:00:00

abstract：:Prevention of lifestyle-related diseases and promotion of physical and mental well-being in adolescents require an understanding of how life situations place adolescents at risk. The most important risk factors for hepatitis B virus (HBV) infection are sexual activity with more than one partner and injecting drug use....

journal_title：Vaccine

authors： Meheus A

更新日期：2000-02-18 00:00:00

abstract：:We hypothesized that the ability of BCG vaccination to protect against Mycobacterium tuberculosis is less in hosts exposed to chronic helminthes infection compared to unexposed individuals. To test this hypothesis we evaluated the efficacy of BCG vaccination in protecting against M. tuberculosis challenge in Schistoso...

journal_title：Vaccine

authors： Elias D,Akuffo H,Pawlowski A,Haile M,Schön T,Britton S

更新日期：2005-02-03 00:00:00

abstract：BACKGROUND:By the time clinical symptoms of Alzheimer's disease (AD) manifest in patients there is already substantial tau pathology in the brain. Recent evidence also suggests that tau pathology can become self-propagating, further accelerating disease progression. Over the last decade several groups have tested the e...

journal_title：Vaccine

authors： Davtyan H,Chen WW,Zagorski K,Davis J,Petrushina I,Kazarian K,Cribbs DH,Agadjanyan MG,Blurton-Jones M,Ghochikyan A

更新日期：2017-04-11 00:00:00

abstract：:The immunological enhancement characteristics of the immunopotentiator CVC1302 were evaluated for foot-and-mouth disease virus (FMDV) inactivated vaccine in pigs. Eight-week-old piglets were vaccinated with the foot-and-mouth disease (FMD) vaccine alone (FMD-vaccine group) or with the addition of CVC1302 (FMD-CVC1302 ...

journal_title：Vaccine

authors： Chen J,Yu X,Zheng Q,Hou L,Du L,Zhang Y,Qiao X,Hou J,Huang K

更新日期：2018-12-18 00:00:00

abstract：:Protective mechanisms underlying the responses to mucosal vaccination are not yet clearly defined. Using the natural mouse pneumovirus pathogen, pneumonia virus of mice (PVM), we explore responses of wild type and interferon-gamma (IFNgamma) receptor gene-deleted mice to virulent challenge after mucosal vaccination wi...

journal_title：Vaccine

authors： Ellis JA,Martin BV,Waldner C,Dyer KD,Domachowske JB,Rosenberg HF

更新日期：2007-01-22 00:00:00

abstract：:The annual winter outbreak of influenza is one of the major cause of morbidity and mortality among frail elderly people. The aim of the present study was to identify prevalence and predictors of influenza vaccination in a large European population of frail and old people living in community. This was an observational ...

journal_title：Vaccine

authors： Landi F,Onder G,Carpenter I,Garms-Homolova V,Bernabei R

更新日期：2005-06-10 00:00:00

abstract：:Protein C deletion mutants of West Nile virus (WNV) were evaluated for their potential use as live virus vaccine candidates in vivo. Double and triple mutants carrying small deletions and second-site point mutations, as well as mutants with large deletions of 36 and 37 amino acid residues were tested in a stringent mo...

journal_title：Vaccine

authors： Schlick P,Kofler RM,Schittl B,Taucher C,Nagy E,Meinke A,Mandl CW

更新日期：2010-08-16 00:00:00

abstract：:It has been hypothesized that antibody induced by Plasmodium falciparum circumsporozoite protein vaccine would be effective against endemic human malaria. In a malaria endemic region of Kenya, 76 volunteers, in 38 pairs sleeping adjacently, were immunized with subunit circumsporozoite protein Asn-Ala-Asn-Pro tetrapept...

journal_title：Vaccine

authors： Sherwood JA,Copeland RS,Taylor KA,Abok K,Oloo AJ,Were JB,Strickland GT,Gordon DM,Ballou WR,Bales JD Jr,Wirtz RA,Wittes J,Gross M,Que JU,Cryz SJ,Oster CN,Roberts CR,Sadoff JC

更新日期：1996-06-01 00:00:00

abstract：:Seneca Valley virus (SVV) infection in pigs is associated with porcine idiopathic vesicular disease (PIVD). Outbreaks of SVV infection in pig herds have been reported in several Asia and Americas countries. Recently, a series of outbreaks of SVV infection occurred in China, Canada, Thailand and the United States. Howe...

journal_title：Vaccine

authors： Yang F,Zhu Z,Cao W,Liu H,Zhang K,Tian H,Liu X,Zheng H

更新日期：2018-02-01 00:00:00

abstract：:Streptococcus pneumoniae is the leading cause of bacterial pneumonia, meningitis and sepsis in children worldwide. Despite available evidence on pneumococcal conjugate vaccine (PCV) impact on pneumonia hospitalizations in children, studies demonstrating PCV impact in morbidity and mortality in middle-income countries ...

journal_title：Vaccine

authors： Suarez V,Michel F,Toscano CM,Bierrenbach AL,Gonzales M,Alencar AP,Ruiz Matus C,Andrus JK,de Oliveira LH

更新日期：2016-09-07 00:00:00

abstract：:Numerous evidence demonstrate Type 1 diabetes (T1D) is due to a loss of immune tolerance to islet antigens, and CD8(+) T cells play an important role in the development of T1D in NOD mice. The novel coinhibitory receptor BTLA may have a regulatory role in maintaining peripheral tolerance, however, its role in autoimmu...

journal_title：Vaccine

authors： Li S,Zhang M,Xiang F,Zhao J,Jiang C,Zhu J

更新日期：2011-10-13 00:00:00

abstract：BACKGROUND:The combined hexavalent diphtheria-tetanus-pertussis-hepatitis B-inactivated poliomyelitis - Haemophilus influenzae type b conjugate vaccine (Infanrix hexa™; DTPa-HBV-IPV/Hib: GlaxoSmithKline Vaccines) induces robust responses to the HBV component when administered at 3, 5 and 11-12 months of age. We assesse...

journal_title：Vaccine

authors： Avdicova M,Crasta PD,Hardt K,Kovac M

更新日期：2015-05-28 00:00:00

abstract：:A systematic review was performed to assess the safety and immunogenicity of the prepandemic H5N1 influenza vaccines licensed so far. A bibliographic search according to the COSI protocol was carried out and 8 of 235 potentially relevant publications were selected. Quality assessment was defined with both CASP and Jad...

journal_title：Vaccine

authors： Prieto-Lara E,Llanos-Méndez A

更新日期：2010-06-11 00:00:00

abstract：:In this proof-of-concept study we report the use of <15 nm, water soluble, inorganic nanoparticles as a vaccine delivery system for a blood stage malaria vaccine. The recombinant malarial antigen, Merozoite Surface Protein 1 (rMSP1) of Plasmodium falciparum served as the model vaccine. The rMSP1 was covalently conjuga...

journal_title：Vaccine

authors： Pusic K,Xu H,Stridiron A,Aguilar Z,Wang A,Hui G

更新日期：2011-11-08 00:00:00

abstract：PURPOSE:Patients undergoing chemotherapy often fail to develop robust responses to influenza vaccination. Compared to standard-dose influenza vaccine (SD), high-dose influenza vaccine (HD) has shown improved immunogenicity and protection against influenza illness in adults 65 years and older. This study compared the im...

journal_title：Vaccine

authors： Jamshed S,Walsh EE,Dimitroff LJ,Santelli JS,Falsey AR

更新日期：2016-01-27 00:00:00

abstract：:An inactivated hepatitis A vaccine was given to 104 seronegative volunteers aged between 19 and 60 years according to two schedules: 0, 1 and 2 months or 0, 1 and 6 months. The vaccine was well tolerated and 97 and 100% of vaccinees developed a serum antibody response following a single and two doses of vaccine respec...

journal_title：Vaccine

authors： Tilzey AJ,Palmer SJ,Barrow S,Perry KR,Tyrell H,Safary A,Banatvala JE

更新日期：1992-01-01 00:00:00

abstract：:The full-length ecdysone receptor cDNA of Choristoneura fumiferana (CfEcR-B) was cloned into bacterial expression systems and the recombinant protein was expressed either with a His-tag (His-EcR-B) or glutathione-S-transferase (GST) fusion (GST-EcR-B). The His-EcR-B was expressed mostly as insoluble aggregates, while ...

journal_title：Vaccine

authors： Yang DH,Makhmoudova A,Arif BM,Feng Q,Retnakaran A,Palli SR,Krell PJ

更新日期：2006-04-12 00:00:00

abstract：:This work demonstrates the presence of immune regulatory cells in the cervical lymph nodes draining Bacillus Calmette-Guérin (BCG) vaccinated site on the dorsum of the ear in guinea pigs. It is shown that whole cervical lymph node cells did not proliferate in vitro in the presence of soluble mycobacterial antigens (PP...

journal_title：Vaccine

authors： Vergkizi S,Nikolakakis I

更新日期：2020-11-10 00:00:00

abstract：BACKGROUND:We aim to determine the vaccination coverage of social and healthcare workers in International sites of Samusocial, providing emergency care to homeless people, and to assess factors associated with having received necessary doses at adulthood. METHODS:Data on immunization coverage of social and healthcare ...

journal_title：Vaccine

authors： Marshall E,Salmon D,Bousfiha N,Togola Y,Ouedraogo F,Santantonio M,Dieng CK,Tartière S,Emmanuelli X

更新日期：2017-09-18 00:00:00

abstract：:DNA isolates from a number of established cell lines have been tested for their transforming capacity in the NIH3T3 transformation assay. It has been found that this assay can be used to quantify the amount of transforming DNA at a submicrogram to milligram level. This assay system has been applied to validate the red...

journal_title：Vaccine

authors： van Meel FC,Steenbakkers PG,Bos E

更新日期：1985-12-01 00:00:00

abstract：PURPOSE:We sought to understand the relative advantage of pharmacies compared to doctors' offices for delivering HPV vaccination to adolescents. METHODS:Participants were a national sample of 1500 U.S. parents of adolescents ages 11-17 recruited in 2014-15. In an online survey, items informed by Diffusion of Innovatio...

journal_title：Vaccine

authors： Shah PD,Marciniak MW,Golden SD,Trogdon JG,Golin CE,Brewer NT

更新日期：2018-06-07 00:00:00

abstract：BACKGROUND:This study examined the transmissibility between young children of an intranasally administered live attenuated human parainfluenza virus type 3 (HPIV3)-cp45 vaccine candidate. METHODS:Eighty subjects were enrolled in playgroups among whom there was at least one infected vaccinee in close contact with a ser...

journal_title：Vaccine

authors： Madhi SA,Cutland C,Zhu Y,Hackell JG,Newman F,Blackburn N,Murphy BR,Belshe RB,Karron RA,Deatly AM,Gruber WC,Bernstein DI,Wright PF

更新日期：2006-03-20 00:00:00

abstract：:A hospital-based case-control study was carried out at the Vilela Children's Hospital in Rosario, Argentina, to measure the protection conferred by BCG vaccination against tuberculosis (TB). The study included 148 newly diagnosed cases of TB (75 males and 73 females, mean age 3.34+/-2.97 years, S.D.), 134 of them with...

journal_title：Vaccine

authors： Bonifachich E,Chort M,Astigarraga A,Diaz N,Brunet B,Pezzotto SM,Bottasso O

更新日期：2006-04-05 00:00:00

abstract：BACKGROUND:British Columbia (BC) introduced a school-based HPV vaccine program in September 2008. As part of the HPV vaccine program evaluation, we determined the type-specific HPV prevalence in a population-based sample of women presenting for routine cervical cancer screening in the province. METHODS:From June 2010 ...

journal_title：Vaccine

authors： Ogilvie GS,Cook DA,Taylor DL,Rank C,Kan L,Yu A,Mei W,van Niekerk DJ,Coldman AJ,Krajden M

更新日期：2013-02-04 00:00:00

abstract：:The co-administration of the tetravalent meningococcal conjugate vaccine, MenACWY-TT, with a licensed hepatitis A and B vaccine, HepA/B (Twinrix(®)), was compared to their separate administration in this open, randomised, controlled study. Healthy subjects 11-17 years of age (n=611) were randomised (3:1:1) to receive ...

journal_title：Vaccine

authors： Østergaard L,Silfverdal SA,Berglund J,Flodmark CE,West C,Bianco V,Baine Y,Miller JM

更新日期：2012-01-17 00:00:00

abstract：:The ability of bioinformatics to characterize genomic sequences from pathogenic bacteria for prediction of genes that may encode vaccine candidates, e.g. surface localized proteins, has been evaluated. By applying appropriate tools for genomic mining to the published sequence of Haemophilus influenzae Rd genome, it wa...

journal_title：Vaccine

authors： Chakravarti DN,Fiske MJ,Fletcher LD,Zagursky RJ

更新日期：2000-11-08 00:00:00

abstract：:HIV vaccines of the first generation are, in contrast to most currently licensed vaccines, unlikely to provide sterilizing immunity against infection with HIV. However, they are expected to exert a beneficial effect on the maintenance of CD4 T-cell counts by reducing viral load. There is a recognized need for clarifyi...

journal_title：Vaccine

authors： Fruth U

更新日期：2009-03-23 00:00:00