Schistosoma mansoni infection reduces the protective efficacy of BCG vaccination against virulent Mycobacterium tuberculosis.

abstract：:Although studies have described factors associated with pertussis hospitalization in children, data on adult hospitalization are sparse. We examined the association between patient characteristics and hospitalization among older adults with pertussis. We conducted a nested case-control study of participants in the 45 ...

journal_title：Vaccine

authors： Karki S,McIntyre P,Newall AT,MacIntyre CR,Banks E,Liu B

更新日期：2015-10-13 00:00:00

abstract：:The presence of resident Langerhans cells (LCs) in the epidermis makes the skin an attractive target for DNA vaccination. However, reliable animal models for cutaneous vaccination studies are limited. We demonstrate an ex vivo human skin model for cutaneous DNA vaccination which can potentially bridge the gap between ...

journal_title：Vaccine

authors： Ng KW,Pearton M,Coulman S,Anstey A,Gateley C,Morrissey A,Allender C,Birchall J

更新日期：2009-10-09 00:00:00

abstract：:Immunization with a combination of several virulence-associated proteins is one of the strategies of developing effective protein-based vaccines to enhance the protection against Streptococcus pneumoniae. In this study, we evaluated the protection effects against pneumococcal infection caused by S. pneumoniae TIGR4 in...

journal_title：Vaccine

authors： Cao J,Chen D,Xu W,Chen T,Xu S,Luo J,Zhao Q,Liu B,Wang D,Zhang X,Shan Y,Yin Y

更新日期：2007-06-28 00:00:00

abstract：:We investigated whether a combined DNA vaccine delivered together with the IL-15 gene (DNA-IL-15(+)) enhanced the immune response against Brucella abortus in mice. Mice vaccinated with DNA-IL-15(+) developed a robust humoral response; Brucella-specific antibodies exhibited a dominance of immunoglobulin G2a (IgG2a) ove...

journal_title：Vaccine

authors： Hu XD,Chen ST,Li JY,Yu DH,Yi-Zhang,Cai H

更新日期：2010-03-11 00:00:00

abstract：:A randomized, double-blind trial comparing a diphtheria-tetanus-acellular pertussis vaccine (DTaP) (pertussis toxoid and filamentous hemagglutinin) with a whole-cell vaccine (DTwP) was conducted. A case-contact study was nested in the trial to estimate absolute efficacy. From 1990 through 1994, 4181 children were rand...

journal_title：Vaccine

authors： Simondon F,Preziosi MP,Yam A,Kane CT,Chabirand L,Iteman I,Sanden G,Mboup S,Hoffenbach A,Knudsen K,Guiso N,Wassilak S,Cadoz M

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of the monovalent rotavirus vaccine (RV1) to prevent rotavirus diarrhea admissions to emergency departments (ED) in Colombia. METHODS:A multicenter case-control study was carried out in six Colombian cities from 2011 to January, 2013. Cases were laboratory confirmed rotavirus diar...

journal_title：Vaccine

authors： Cotes-Cantillo K,Paternina-Caicedo A,Coronell-Rodríguez W,Alvis-Guzmán N,Parashar UD,Patel M,De la Hoz-Restrepo F

更新日期：2014-05-23 00:00:00

abstract：:Our current knowledge allows the generation of transgenic plants that efficiently produce heterologous proteins from plant, bacterial, fungal or animal origin. Among all types of recombinant proteins, antibodies are particularly attractive because of their ability to specifically recognize and bind virtually any type ...

journal_title：Vaccine

authors： Peeters K,De Wilde C,De Jaeger G,Angenon G,Depicker A

更新日期：2001-03-21 00:00:00

abstract：:Malaria transmission-blocking vaccines (TBV) targeting sexual stages of the parasite represent an ideal intervention to reduce the burden of the disease and eventual elimination at the population level in endemic regions. Immune responses against sexual stage antigens impair the development of parasite inside the mosq...

journal_title：Vaccine

authors： Kumar R,Ray PC,Datta D,Bansal GP,Angov E,Kumar N

更新日期：2015-09-22 00:00:00

abstract：:Finding adjuvants in order to enhance immune responses against target immunogens has been a major and recurrent issue for the vaccine industry. It is yet to be solved, most particularly in the context of a growing interest in designing new types of vaccines capable of eliciting Th1 immune responses. A review of synthe...

journal_title：Vaccine

authors： Moingeon P,Haensler J,Lindberg A

更新日期：2001-08-14 00:00:00

abstract：BACKGROUND:Typhoid fever remains a major public health problem in low- and middle-income countries where children aged 2-14 years bear the greatest burden. Vi polysaccharide is poorly immunogenic in children <2 years of age, and protection in adults is modest. The limitations of Vi polysaccharide vaccines can be overco...

journal_title：Vaccine

authors： Capeding MR,Teshome S,Saluja T,Syed KA,Kim DR,Park JY,Yang JS,Kim YH,Park J,Jo SK,Chon Y,Kothari S,Yang SY,Ham DS,Ryu JH,Hwang HS,Mun JH,Lynch JA,Kim JH,Kim H,Excler JL,Sahastrabuddhe S

更新日期：2018-06-18 00:00:00

abstract：:The continuous outbreaks of fatal Newcastle disease (ND) in commercial poultry flocks demonstrate that current vaccination strategies are not fully efficacious and should be improved by new generation of vaccines. In this context, maternally immune conventional layer chickens were vaccinated in ovo with a turkey herpe...

journal_title：Vaccine

authors： Rauw F,Gardin Y,Palya V,Anbari S,Lemaire S,Boschmans M,van den Berg T,Lambrecht B

更新日期：2010-01-08 00:00:00

abstract：:Human adenoviruses (AdVs) have been extensively studied as vectors for gene therapy and vaccination. However, little attention has been paid to AdV vaccine development and treatment. Currently, there is a lack of information concerning the immunogenicity of AdV major capsid proteins. Here, using AdV7 as a model, we co...

journal_title：Vaccine

authors： Hu K,Fu M,Guan X,Zhang D,Deng X,Xiao Y,Chen R,Liu H,Hu Q

更新日期：2018-07-05 00:00:00

abstract：:Metered-dose propellant-driven small particle aerosols of a killed whole bacterium, Streptococcus suis, were produced and characterized for their aerodynamic particle sizes and antigenicity as potential respiratory mucosal vaccines against S. suis infections in swine. To facilitate the efficient delivery of such vacci...

journal_title：Vaccine

authors： Brown AR,George DW,Matteson DK

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:4CMenB (Bexsero), a vaccine developed against invasive meningococcal disease caused by capsular group B strains (MenB), was recently licensed for use by the European Medicines Agency. Assessment of 4CMenB strain coverage in specific epidemiologic settings is of primary importance to predict vaccination impac...

journal_title：Vaccine

authors： Frosi G,Biolchi A,Lo Sapio M,Rigat F,Gilchrist S,Lucidarme J,Findlow J,Borrow R,Pizza M,Giuliani MM,Medini D

更新日期：2013-10-09 00:00:00

abstract：BACKGROUND:Each year a substantial number of Dutch elderly suffers from herpes zoster (HZ), caused by the reactivation of the varicella zoster virus (VZV). A potential complication of HZ is postherpetic neuralgia (PHN) which results in a prolonged loss of quality of life. A large randomized clinical trial, labelled the...

journal_title：Vaccine

authors： de Boer PT,Pouwels KB,Cox JM,Hak E,Wilschut JC,Postma MJ

更新日期：2013-02-18 00:00:00

abstract：BACKGROUND:Evidence that respiratory infections trigger stroke suggests that influenza or pneumococcal vaccination might prevent stroke. We aimed to investigate whether influenza or pneumococcal vaccination or both together were associated with reduced risk of stroke or transient ischaemic attack (TIA). METHODS:We use...

journal_title：Vaccine

authors： Siriwardena AN,Asghar Z,Coupland CC

更新日期：2014-03-10 00:00:00

abstract：:Although the USA is considered an area of 'low' endemicity for hepatitis B infection, the incidence of new cases, the prevalence of carriers, and the burden of acute and chronic disease place hepatitis B among the most important communicable diseases. It is estimated that 300,000 new cases of hepatitis B infection occ...

journal_title：Vaccine

authors： Kane M

更新日期：1995-01-01 00:00:00

abstract：:Most traditional vaccines are administered via the intramuscular route. Other routes of administration however, can induce equal or improved protective memory responses and might provide practical advantages such as needle-free immunization, dose sparing and induction of tissue-specific (mucosal) immunity. Here we exp...

journal_title：Vaccine

authors： van Aalst S,Jansen MAA,Ludwig IS,van der Zee R,van Eden W,Broere F

更新日期：2018-03-07 00:00:00

abstract：:The levels of antibody against measles, mumps, and rubella were determined at 5-6 years postimmunization in 468 children vaccinated with two different trivalent vaccines. The proportions of children without detectable antibody levels were 12 and 3.6% for measles (p < 0.001), 14.9 and 7% for mumps (p = 0.006), and 3.3 ...

journal_title：Vaccine

authors： Boulianne N,De Serres G,Ratnam S,Ward BJ,Joly JR,Duval B

更新日期：1995-11-01 00:00:00

abstract：:Rotavirus is acknowledged to be a major cause of acute gastroenteritis in infants and young children. As gastroenteritis due to rotavirus is a public health problem and two new vaccines are currently available, we investigated the rotavirus burden and developed a cost-effectiveness analysis, using data collected in th...

journal_title：Vaccine

authors： Panatto D,Amicizia D,Ansaldi F,Marocco A,Marchetti F,Bamfi F,Giacchino R,Tacchella A,Del Buono S,Gasparini R

更新日期：2009-05-26 00:00:00

abstract：INTRODUCTION:Endemic measles persists in China, despite >95% reported coverage of two measles-containing vaccine doses and nationwide campaign that vaccinated more than 100 million children in 2010. In 2011, almost half of the 9943 measles cases in China occurred in children eligible for measles vaccination. We conduct...

journal_title：Vaccine

authors： Hao L,Ma C,Wannemuehler KA,Su Q,An Z,Cairns L,Quick L,Rodewald L,Liu Y,He H,Xu Q,Ma Y,Yu W,Zhang N,Li L,Wang N,Luo H,Wang H,Gregory CJ

更新日期：2016-12-12 00:00:00

abstract：:Killed whole-cell preparations were used as bacterins against leptospirosis. As this type of protection is considered to be serogroup-specific, several serogroups were added to the usual vaccines, and the most pathogenic serovar was chosen for each group. Different leptospire extracts were evaluated for their protecti...

journal_title：Vaccine

authors： Sonrier C,Branger C,Michel V,Ruvoën-Clouet N,Ganière JP,André-Fontaine G

更新日期：2000-08-15 00:00:00

abstract：:This study examines the potential clinical and economic benefits for adults arising from paediatric pneumococcal vaccination in the UK. A UK birth cohort model with a 10-year horizon and using a primary 4-dose paediatric 7-valent pneumococcal conjugate vaccine (PCV) schedule was populated with 1999 morbidity and morta...

journal_title：Vaccine

authors： McIntosh ED,Conway P,Willingham J,Hollingsworth R,Lloyd A

更新日期：2005-02-25 00:00:00

abstract：:Nucleic acid vaccination has many potential advantages over traditional methods, but suffers from the fact that DNA vaccines tend to be relatively poorly immunogenic. Attempts to enhance DNA vaccine immunogenicity have included the addition of cytokine-encoding plasmids into the formulation, as well as the use of hete...

journal_title：Vaccine

authors： Nimal S,McCormick AL,Thomas MS,Heath AW

更新日期：2005-06-10 00:00:00

abstract：BACKGROUND:Rotavirus (RV) infection is the primary cause of severe gastroenteritis in children aged <5 years in Germany and worldwide. In 2013 the German Standing Committee on Vaccination (STIKO) developed a national recommendation for routine RV-immunization of infants. To support informed decision-making we predicted...

journal_title：Vaccine

authors： Weidemann F,Dehnert M,Koch J,Wichmann O,Höhle M

更新日期：2014-09-08 00:00:00

abstract：:The shelf life and thermal stability of an antifertility vaccine, in which gonadotropin subunits are linked to carriers such as tetanus toxoid and cholera toxin chain B and has successfully completed phase-I clinical trials at five centres in India, was studied. The vaccine adsorbed on alum was stored at three tempera...

journal_title：Vaccine

authors： Alam A,Singh O,Talwar GP

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:To evaluate the immunological impact of the 23-valent pneumococcal polysaccharide vaccine (23vPPS) at 12 months, for children who have received zero to three infant doses of seven-valent pneumococcal conjugate vaccine (PCV), on responses to a subsequent exposure to a small dose of 23vPPS (mPPS). METHODS:Fiv...

journal_title：Vaccine

authors： Russell FM,Carapetis JR,Balloch A,Licciardi PV,Jenney AW,Tikoduadua L,Waqatakirewa L,Pryor J,Nelson J,Byrnes GB,Cheung YB,Tang ML,Mulholland EK

更新日期：2010-04-26 00:00:00

abstract：:These studies were performed to determine the effects of GPI-0100, a semi synthetic Quillaja Saponin analog, formulated with herpes simplex virus type-1 (HSV-1) glycoprotein D (gD) on immunity to HSV. SKH-1 hairless mice, used as a model of herpes labialis, inoculated with HSV-1 results in facial lesions, virus replic...

journal_title：Vaccine

authors： Quenelle DC,Collins DJ,Marciani DJ,Kern ER

更新日期：2006-03-06 00:00:00

abstract：:Myostatin negatively regulates skeletal muscle growth. It was found that active immunization with myostatin-specific vaccine blocked myostatin function in vivo, which resulted in increase of body weight and muscle composition in mice. However, traditional vaccine and its administration method are expensive and laborio...

journal_title：Vaccine

authors： Zhang T,Yang H,Wang R,Xu K,Xin Y,Ren G,Zhou G,Zhang C,Wang L,Zhang Z

更新日期：2011-10-26 00:00:00

abstract：BACKGROUND:In England, coverage for childhood vaccines have decreased since 2012/13 in the context of an increasingly visible anti-vaccination discourse. We determined whether anti-vaccination sentiment is the likely cause of this decline in coverage. METHODS:Descriptive study triangulating a range of data sources (va...

journal_title：Vaccine

authors： Edelstein M,Müller M,Ladhani S,Yarwood J,Salathé M,Ramsay M

更新日期：2020-07-14 00:00:00