Abstract：
:A prototype H7 influenza vaccine constructed based on the H7N7 outbreak in 2003 was tested for the protective efficacy against the novel H7N9 virus in a lethal murine challenge model. Serum samples from vaccinated mice showed significant neutralizing activity against the H7N9 virus and the mice were completely protected with no significant weight loss. The results have direct implications on how to overcome potential vaccine shortage and identify donors for immune sera for passive immunization.
journal_name
Vaccinejournal_title
Vaccineauthors
Tang LH,Lim JH,Kuah LF,Lau YFdoi
10.1016/j.vaccine.2014.07.087subject
Has Abstractpub_date
2014-09-22 00:00:00pages
5375-8issue
42eissn
0264-410Xissn
1873-2518pii
S0264-410X(14)01069-Xjournal_volume
32pub_type
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