Impact of hepatitis B vaccination in a highly endemic area of south Italy and long-term duration of anti-HBs antibody in two cohorts of vaccinated individuals.

abstract：:The chloroplast genetic engineering offers a number of unique advantages including high level of transgene expression, multi-gene expression in single transformation event and transgene containment due to maternal inheritance. Hyper-expression of vaccine antigens or therapeutic proteins in transgenic chloroplasts (lea...

journal_title：Vaccine

authors： Daniell H,Chebolu S,Kumar S,Singleton M,Falconer R

更新日期：2005-03-07 00:00:00

abstract：:Ricin is a plant toxin that is a CDC level B biothreat. Our recombinant ricin A chain vaccine (RiVax), which contains mutations in both known toxic sites, has no residual toxicity at doses at least 800 times the immunogenic dose. RiVax without adjuvant given intramuscularly (i.m.) protected mice against intraperitonea...

journal_title：Vaccine

authors： Smallshaw JE,Richardson JA,Vitetta ES

更新日期：2007-10-16 00:00:00

abstract：:The world is facing the rising emergency of SARS-CoV-2. The outbreak of COVID-19 has caused a global public health and economic crisis.Recent epidemiological studies have shown that a possible association of BCG vaccination program with decreased COVID-19-related risks, suggesting that BCG may provide protection again...

journal_title：Vaccine

authors： Tomita Y,Sato R,Ikeda T,Sakagami T

更新日期：2020-09-22 00:00:00

abstract：:When the hypothesis of a link between vaccination and a possible adverse outcome arises, further investigation is required to confirm or refute the suspicion. Given the rarity of most serious adverse effects, a case-control approach will often be chosen. This paper discusses aspects of the design, analysis and interpr...

journal_title：Vaccine

authors： Smeeth L,Rodrigues LC,Hall AJ,Fombonne E,Smith PG

更新日期：2002-06-07 00:00:00

abstract：BACKGROUND:India has faced considerable challenges in eradicating polio. Uttar Pradesh (UP) and Bihar are the two states in India where transmission of polio has never been interrupted. Private pediatricians are important stakeholders for vaccine delivery and maintaining public confidence in vaccines. The purpose of th...

journal_title：Vaccine

authors： Choudhury P,Thacker N,Gargano LM,Weiss PS,Vashishtha VM,Amladi T,Pazol K,Orenstein WA,Omer SB,Hughes JM

更新日期：2011-10-26 00:00:00

abstract：BACKGROUND:The internet is a source of health information for many consumers. However, little is known about the availability of online resources about immunisation (for children and adults) directed at refugee and migrant populations. The aim of this study was to evaluate the health literacy demand (understandability,...

journal_title：Vaccine

authors： Abdi I,Murphy B,Seale H

更新日期：2020-09-22 00:00:00

abstract：:The adenylate cyclase (CyaA) produced by Bordetella pertussis is able to deliver CD8+ and CD4+ T-cell epitopes genetically grafted within the catalytic domain of the molecule into antigen presenting cells in vivo. We develop now a new approach in which peptides containing CD8+ epitopes are chemically linked to CyaA. W...

journal_title：Vaccine

authors： Fayolle C,Bauche C,Ladant D,Leclerc C

更新日期：2004-12-16 00:00:00

abstract：:We recently identified a population of 10% of infants who respond with sub-protective antibody levels to most routine primary pediatric vaccinations due to altered innate and adaptive immune responses. We term these infants as low vaccine responders (LVRs). Here we report new data showing that TLR7/8 agonist - R848 st...

journal_title：Vaccine

authors： Surendran N,Nicolosi T,Pichichero M

更新日期：2016-11-11 00:00:00

abstract：:Strains of Newcastle disease virus (NDV) can be separated into genotypes based on genome differences even though they are antigenically considered to be of a single serotype. It is widely recognized that an efficacious Newcastle disease (ND) vaccine made with any NDV does induce protection against morbidity and mortal...

journal_title：Vaccine

authors： Miller PJ,King DJ,Afonso CL,Suarez DL

更新日期：2007-10-10 00:00:00

abstract：:Successful vaccination of mice against an otherwise lethal challenge with the Peru strain of Trypanosoma cruzi necessitates the induction of a strong cell mediated immune response. Previously, immunization of mice with the paraflagellar rod proteins from Trypanosoma cruzi90% reduction in parasitemia in immunized mice ...

journal_title：Vaccine

authors： Wrightsman RA,Manning JE

更新日期：2000-01-31 00:00:00

abstract：:Chlamydia trachomatis causes respiratory and sexually transmitted infections. Here, we tested a vaccine formulated with the recombinant major outer membrane protein from C. trachomatis mouse pneumonitis (CT-MoPn) for its ability to protect mice against an intranasal (i.n.) challenge. The adjuvants CpG and Montanide we...

journal_title：Vaccine

authors： Ralli-Jain P,Tifrea D,Cheng C,Pal S,de la Maza LM

更新日期：2010-11-10 00:00:00

abstract：:We reported previously on the development of a Bacillus anthracis vaccine strain expressing high levels of recombinant protective antigen (rPA) [Cohen et al., Infec Immun 2000;68(8):4549-58]. To further explore the potential of the B. anthracis platform, we generated several attenuated strains expressing lethal toxin ...

journal_title：Vaccine

authors： Mendelson I,Gat O,Aloni-Grinstein R,Altboum Z,Inbar I,Kronman C,Bar-Haim E,Cohen S,Velan B,Shafferman A

更新日期：2005-12-01 00:00:00

abstract：INTRODUCTION:Vaccination of pregnant women protects both women and their newborns against some infectious diseases. Thailand implemented tetanus toxoid (TT) vaccination of pregnant women in 1977, which was replaced by tetanus-diphtheria toxoid (dT) vaccination in 2005. The tetanus-diphtheria-acellular pertussis (Tdap) ...

journal_title：Vaccine

authors： Wanlapakorn N,Maertens K,Thongmee T,Srimuan D,Thatsanathorn T,Van Damme P,Leuridan E,Poovorawan Y

更新日期：2020-10-14 00:00:00

abstract：:The correlation between the antigen content of inactivated Newcastle disease (ND) oil emulsion-vaccines and the serological response after immunisation was studied. The haemagglutinin-neuraminidase (HN) and fusion (F) proteins of Newcastle disease virus (NDV) were quantified in 33 inactivated oil-adjuvanted ND vaccine...

journal_title：Vaccine

authors： Maas RA,Komen M,van Diepen M,Oei HL,Claassen IJ

更新日期：2003-07-04 00:00:00

abstract：:Two outbreaks of hepatitis A started almost simultaneously in a maternal school and in a day care centre located at opposite sides of Florence, Italy, at the end of 2002. Both of them originated from immigrant children, and in both cases, hepatitis A was initially not recognised due to aspecific symptoms. While vaccin...

journal_title：Vaccine

authors： Bonanni P,Franzin A,Staderini C,Pitta M,Garofalo G,Cecconi R,Santini MG,Lai P,Innocenti B

更新日期：2005-03-18 00:00:00

abstract：:Seven volunteers involved in flavivirus studies have been immunized with commercial Japanese encephalitis and yellow fever vaccines JE-VAX and YF-VAX. Strong homologous and cross-reactive with West Nile virus (WNV) antibody responses with titers 1:1600 to 1:51200 were found in all donors. All donors developed high lev...

journal_title：Vaccine

authors： Yamshchikov G,Borisevich V,Kwok CW,Nistler R,Kohlmeier J,Seregin A,Chaporgina E,Benedict S,Yamshchikov V

更新日期：2005-09-15 00:00:00

abstract：:Antibodies have the potential to be therapeutic reagents for malaria. Here we describe the production of a novel phage antibody display library against the C-terminal 19kDa region of the Plasmodium yoelii YM merozoite surface protein-1 (MSP1(19)). In vivo studies against homologous lethal malaria challenge show an ant...

journal_title：Vaccine

authors： Vukovic P,Chen K,Qin Liu X,Foley M,Boyd A,Kaslow D,Good MF

更新日期：2002-06-21 00:00:00

abstract：BACKGROUND:The challenge of keeping vaccines cold at health posts given the unreliability of power sources in many low- and middle-income countries and the expense and maintenance requirements of solar refrigerators has motivated the development of passive cold storage devices (PCDs), containers that keep vaccines cold...

journal_title：Vaccine

authors： Norman BA,Nourollahi S,Chen SI,Brown ST,Claypool EG,Connor DL,Schmitz MM,Rajgopal J,Wateska AR,Lee BY

更新日期：2013-10-25 00:00:00

abstract：:Alternative DNA vaccine constructs such as fully synthetic linear expressing cassettes (LECs) offer the advantage of accelerated manufacturing techniques as well as the lack of both antibiotic resistance genes and bacterial contaminants. The speed of manufacture makes LEC technology a possible future vaccination strat...

journal_title：Vaccine

authors： Shen X,Söderholm J,Lin F,Kobinger G,Bello A,Gregg DA,Broderick KE,Sardesai NY

更新日期：2012-11-06 00:00:00

abstract：:During the 2009/10 pandemic of influenza A (H1N1), the American Society of Transplantation and other health organizations recommended that immunocompromised patients should be vaccinated as the key preventive measure. Since there are no data available for the immunogenicity of the unadjuvanted pandemic influenza vacci...

journal_title：Vaccine

authors： Lagler H,Wenisch JM,Tobudic S,Gualdoni GA,Rödler S,Rasoul-Rockenschaub S,Jaksch P,Redlberger-Fritz M,Popow-Kraupp T,Burgmann H

更新日期：2011-09-16 00:00:00

abstract：:Intact (146S) foot-and-mouth disease virions (FMDVs) can dissociate into specific (12S) viral capsid degradation products. Using two single-domain antibody fragments that bind specifically to either 146S or 12S particles we developed two ELISAs for the quantification of these particles in FMDV antigen preparations use...

journal_title：Vaccine

authors： Harmsen MM,Fijten HP,Westra DF,Coco-Martin JM

更新日期：2011-03-24 00:00:00

abstract：:Porcine circovirus type 2 (PCV2) is an economically important swine pathogen and vaccination is the primary tool for the disease control. Previously, we developed a more cost-effective PCV2 virus-like particle (VLP) vaccine by using ELPylation technology. In the present study, we compared the ELPylated VLP (ELP-VLP) P...

journal_title：Vaccine

authors： Li Y,Lin Y,Xin G,Zhou X,Lu H,Zhang X,Xia X,Sun H

更新日期：2020-05-13 00:00:00

abstract：:Measles incidence has decreased dramatically in China due to the implement of measles-containing vaccine (MCV). However, a measles epidemic caused resurgence recently, even among vaccinated individuals. To evaluate the effectiveness of current immunization programs and discuss initiatives for the next step in measles ...

journal_title：Vaccine

authors： Cui A,Zhang Y,Zhu Z,Wang H,Mao N,Song J,Xu W

更新日期：2020-05-08 00:00:00

abstract：BACKGROUND:Germany introduced routine varicella (V) vaccination in 2004. Due to a slightly increased risk of febrile convulsions after first-dose application of combined measles-mumps-rubella-varicella (MMRV) vaccine separate first-dose vaccinations with MMR and monovalent V vaccine were recommended in September 2011. ...

journal_title：Vaccine

authors： Streng A,Liese JG

更新日期：2014-02-12 00:00:00

abstract：:A dengue virus vaccine candidate, rDEN4Delta30, has been previously reported to be safe and immunogenic in humans, but a subset of vaccinees developed asymptomatic rash, elevation of liver enzymes and/or mild neutropenia. In the current study, mutations that had previously been shown to reduce replication of DEN4 viru...

journal_title：Vaccine

authors： Hanley KA,Manlucu LR,Manipon GG,Hanson CT,Whitehead SS,Murphy BR,Blaney JE Jr

更新日期：2004-09-03 00:00:00

abstract：BACKGROUND:This study examined the transmissibility between young children of an intranasally administered live attenuated human parainfluenza virus type 3 (HPIV3)-cp45 vaccine candidate. METHODS:Eighty subjects were enrolled in playgroups among whom there was at least one infected vaccinee in close contact with a ser...

journal_title：Vaccine

authors： Madhi SA,Cutland C,Zhu Y,Hackell JG,Newman F,Blackburn N,Murphy BR,Belshe RB,Karron RA,Deatly AM,Gruber WC,Bernstein DI,Wright PF

更新日期：2006-03-20 00:00:00

abstract：:Genetic immunization holds promise as a vaccination method, but has so far proven ineffective in large primate and human trials. Herein, we examined the relative merits of genetic immunization and peptide immunization using bacteriophage λ. Bacteriophage λ has proven effective in immune challenge models using both imm...

journal_title：Vaccine

authors： Thomas BS,Nishikawa S,Ito K,Chopra P,Sharma N,Evans DH,Tyrrell DL,Bathe OF,Rancourt DE

更新日期：2012-02-01 00:00:00

abstract：:We have previously described the generation of HIV-1 V3-specific cytotoxic T-lymphocytes (CTL) responses in BALB/c (H-2d) mice following immunization with Ty-virus-like particles carrying the V3 loop of gp120 (V3-VLPs) without adjuvant. In this study the effects of various adjuvants on CTL induction by V3-VLPs was exa...

journal_title：Vaccine

authors： Harris SJ,Woodrow SA,Gearing AJ,Adams SE,Kingsman AJ,Layton GT

更新日期：1996-07-01 00:00:00

abstract：:Hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) in about 150,000 individuals in Eurasia, and several hundred cases of hantavirus pulmonary syndrome (HPS) on the American continent annually. There is consequently a need for rapid diagnostics and effective prevention of hantaviral infections. In this stu...

journal_title：Vaccine

authors： Lindkvist M,Lahti K,Lilliehöök B,Holmström A,Ahlm C,Bucht G

更新日期：2007-02-19 00:00:00

abstract：BACKGROUND:We have developed a new oral vaccine against enterotoxigenic Escherichia coli (ETEC), which is the most common cause of bacterial diarrhea in children in developing countries and in travelers. METHODS:The vaccine was tested for safety and immunogenicity alone and together with double-mutant heat-labile toxi...

journal_title：Vaccine

authors： Lundgren A,Bourgeois L,Carlin N,Clements J,Gustafsson B,Hartford M,Holmgren J,Petzold M,Walker R,Svennerholm AM

更新日期：2014-12-12 00:00:00