Booster response to recombinant yeast-derived hepatitis B vaccine in vaccinees whose anti-HBs responses were initially elicited by a plasma-derived vaccine.

abstract：:Generating broadly neutralizing antibodies with candidate vaccines has remained an elusive goal. Consequently, vaccine candidates developed have aimed at eliciting cell-mediated immune effector activities (CMI) that could delay disease progression, and maybe also limit secondary transmission, by controlling virus repl...

journal_title：Vaccine

authors： Gurunathan S,Habib RE,Baglyos L,Meric C,Plotkin S,Dodet B,Corey L,Tartaglia J

更新日期：2009-03-23 00:00:00

abstract：:Tuberculosis caused by Mycobacterium tuberculosis continues to be one of the major public health problems in the world. The eventual control of this disease will require the development of a safe and effective vaccine. One of the approaches receiving a great deal of attention recently is subunit vaccination. An effica...

journal_title：Vaccine

authors： Sable SB,Plikaytis BB,Shinnick TM

更新日期：2007-02-19 00:00:00

abstract：:Despite the extensive use of efficacious pertussis vaccines, Bordetella pertussis infections are still among the main causes for childhood morbidity and mortality. Severe pertussis occurs mostly in very young children, often too young to be sufficiently protected by current vaccines, which require several administrati...

journal_title：Vaccine

authors： Feunou PF,Ismaili J,Debrie AS,Huot L,Hot D,Raze D,Lemoine Y,Locht C

更新日期：2008-10-23 00:00:00

abstract：:We created and produced a novel self-assembling nanoparticle platform for delivery of peptide epitopes that induces CD8(+) and CD4(+)T cells that are protective against Toxoplasma gondii infection. These self-assembling polypeptide nanoparticles (SAPNs) are composed of linear peptide (LP) monomers which contain two co...

journal_title：Vaccine

authors： El Bissati K,Zhou Y,Dasgupta D,Cobb D,Dubey JP,Burkhard P,Lanar DE,McLeod R

更新日期：2014-05-30 00:00:00

abstract：:We have recently developed a transmissible vaccine to immunize rabbits against myxomatosis and rabbit haemorrhagic disease based on a recombinant myxoma virus (MV) expressing the rabbit haemorrhagic disease virus (RHDV) capsid protein [Bárcena et al. Horizontal transmissible protection against myxomatosis and rabbit h...

journal_title：Vaccine

authors： Torres JM,Ramírez MA,Morales M,Bárcena J,Vázquez B,Espuña E,Pagès-Manté A,Sánchez-Vizcaíno JM

更新日期：2000-09-15 00:00:00

abstract：:We have shown previously that expression library immunization is viable alternative approach to induce protective immunity against Neisseria meningitidis serogroup B. In this study we report that few rounds of library screening allow identification of protective pools of defined antigens. A previously reported protect...

journal_title：Vaccine

authors： Yero D,Pajón R,Pérez Y,Fariñas M,Cobas K,Diaz D,Solis RL,Acosta A,Brookes C,Taylor S,Gorringe A

更新日期：2007-07-09 00:00:00

abstract：:The effects of intranasal inoculation with live attenuated, CR influenza virus vaccines on pulmonary function in healthy and asthmatic adults were evaluated in placebo-controlled, double-blind studies. In 46 healthy adult volunteers, there were no statistically significant alterations in pulmonary function as measured...

journal_title：Vaccine

authors： Atmar RL,Bloom K,Keitel W,Couch RB,Greenberg SB

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:This study evaluated the immunogenicity and safety of quadrivalent meningococcal conjugate vaccine using tetanus (T) toxoid as carrier protein (MenACWY-TT) co-administered with combined diphtheria-tetanus-acellular pertussis vaccine (Tdap) versus their separate administration in adolescents and young adults....

journal_title：Vaccine

authors： Rivera L,Schwarz TF,Kim KH,Kim YK,Behre U,Cha SH,Jo DS,Lee J,Lee JS,Cheuvart B,Jastorff A,Van der Wielen M

更新日期：2018-07-25 00:00:00

abstract：BACKGROUND:By the time clinical symptoms of Alzheimer's disease (AD) manifest in patients there is already substantial tau pathology in the brain. Recent evidence also suggests that tau pathology can become self-propagating, further accelerating disease progression. Over the last decade several groups have tested the e...

journal_title：Vaccine

authors： Davtyan H,Chen WW,Zagorski K,Davis J,Petrushina I,Kazarian K,Cribbs DH,Agadjanyan MG,Blurton-Jones M,Ghochikyan A

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:The Advisory Committee on Immunization Practices (ACIP) routinely recommends three vaccines - influenza, hepatitis B, and pneumococcal vaccines - for End-Stage Renal Disease (ESRD) dialysis patients. METHODS:We sought to assess vaccination coverage among fee-for-service (FFS) Medicare beneficiaries with ESR...

journal_title：Vaccine

authors： Shen AK,Kelman JA,Warnock R,Zhang W,Brereton S,McKean S,Wernecke M,Chu S,Gellin BG

更新日期：2017-12-19 00:00:00

abstract：:Estimation of the full disease burden caused by Streptococcus pneumoniae is challenging due to the difficulties in assigning the aetiology especially in lower and upper respiratory infections. We estimated the pneumococcal disease burden by using the vaccine-preventable disease incidence (VPDI) of PHiD-CV10 vaccine (G...

journal_title：Vaccine

authors： Palmu AA,Jokinen J,Nieminen H,Rinta-Kokko H,Ruokokoski E,Puumalainen T,Moreira M,Schuerman L,Borys D,Kilpi TM

更新日期：2018-03-27 00:00:00

abstract：:Insoluble, pure protein particles could be advantageous as single-entity vaccines or as carriers for small peptide epitopes. Dense gas anti-solvent precipitation was employed to produce pure protein particles which were found to be insoluble in water. As particulate and multimerized antigens are more immunogenic and h...

journal_title：Vaccine

authors： White PJ,Anastasopoulos F,Church JE,Kuo CY,Boyd BJ,Hickey PL,Tu LS,Burns P,Lew AM,Heath WR,Davey GM,Pouton CW

更新日期：2008-12-09 00:00:00

abstract：:Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is highly heterogenic. This heterogeneity has an effect on antigenic composition of PRRSV and might create differences in sensitivity to neutralization between isolates. The sensitivity to neutralization could be an important feature of PRRSV isolates because...

journal_title：Vaccine

authors： Martínez-Lobo FJ,Díez-Fuertes F,Simarro I,Castro JM,Prieto C

更新日期：2011-09-16 00:00:00

abstract：BACKGROUND:Current national immunisation schedules differ between countries in terms of vaccine formulation, timing of vaccinations and immunisation programme funding and co-ordination. As a result, some HIV infected paediatric population may be left susceptible to vaccine preventable infections. Vaccines used in healt...

journal_title：Vaccine

authors： Bamford A,Manno EC,Mellado MJ,Spoulou V,Marques L,Scherpbier HJ,Niehues T,Oldakowska A,Rossi P,Palma P,PENTA-vac Group.

更新日期：2016-11-04 00:00:00

abstract：:Malaria remains an important health threat to non-immune travelers with the explosive growth of global travel. Populations at high risk of acquiring malaria infections include once semi-immune travelers who visit friends and relatives, military forces, business travelers and international tourists with destinations to...

journal_title：Vaccine

authors： Teneza-Mora N,Lumsden J,Villasante E

更新日期：2015-12-22 00:00:00

abstract：:Vaccine exposure to temperatures below recommended ranges in the cold chain may decrease vaccine potency of freeze-sensitive vaccines leading to a loss of vaccine investments and potentially places children at risk of contracting vaccine preventable illnesses. This literature review is an update to one previously publ...

journal_title：Vaccine

authors： Hanson CM,George AM,Sawadogo A,Schreiber B

更新日期：2017-04-19 00:00:00

abstract：:The potency assay currently used to evaluate consistency of manufacture for the anthrax vaccine is contingent upon meeting specified parameters after statistical analysis of the percent survival and time to death of vaccinated guinea pigs after challenge with spores of a virulent strain of Bacillus anthracis. During t...

journal_title：Vaccine

authors： Little SF,Webster WM,Ivins BE,Fellows PF,Norris SL,Andrews GP

更新日期：2004-07-29 00:00:00

abstract：BACKGROUND:Poorly managed AEFI undermine immunization programs. Improved surveillance in SEAR countries means more AEFIs but management varies. SEAR brought countries together to share AEFI experiences, and learn more about causality assessment. METHODS:Three day 10 country workshop (9 SEAR; 1 WPR). Participants outli...

journal_title：Vaccine

authors： MacDonald NE,Guichard S,Amarasinghe A,Balakrishnan MR,2014 Inter-country SEAR Workshop Participants.

更新日期：2015-11-27 00:00:00

abstract：:Development of a safe and effective vaccine against human immunodeficiency virus (HIV) is urgent, but many concerns regarding the safety and efficacy of the currently developing vaccines remain. A major hindrance in HIV vaccine development is the genetic diversity, a hallmark of HIV biology, and a poor understanding o...

journal_title：Vaccine

authors： Mukai T,Kurosu T,Kinomoto M,Komoto S,Shiraga M,Auwanit W,Ikuta K

更新日期：2002-01-15 00:00:00

abstract：BACKGROUND:While childhood vaccines are safe and effective, some parents remain hesitant to vaccinate their children, which has led to outbreaks of vaccine preventable diseases. The goal of this systematic review was to identify and summarize the range of beliefs around childhood vaccines elicited using open-ended ques...

journal_title：Vaccine

authors： Gidengil C,Chen C,Parker AM,Nowak S,Matthews L

更新日期：2019-10-23 00:00:00

abstract：PURPOSE:To characterize groups of primary healthcare physicians according to sociodemographic data, years of professional experience and knowledge of and attitudes to influenza, and to evaluate differences between groups with respect to influenza vaccination in the 2011-2012 season. METHODS:We carried out an anonymous...

journal_title：Vaccine

authors： Antón-Ladislao A,García-Gutiérrez S,Soldevila N,González-Candelas F,Godoy P,Castilla J,Mayoral JM,Astray J,Martín V,Tamames S,Toledo D,Aguirre U,Domínguez A,CIBERESP Working Group for the Survey on Influenza Vaccination in Prim

更新日期：2015-02-11 00:00:00

abstract：:In case of a bite by a rabies infected animal, the World Health Organisation recommends a prophylactic treatment including the administration of Human Rabies Immunoglobulins (HRIGs) or highly purified F(ab')2 fragments produced from Equine Rabies Immunoglobulin (F(ab')2 - ERIGs). According to international regulation,...

journal_title：Vaccine

authors： Korimbocus J,Dehay N,Tordo N,Cano F,Morgeaux S

更新日期：2016-06-14 00:00:00

abstract：:C57BL/6 (B6) mice were immunized with a highly antigenic 10-mer peptide (P12-10), which is encoded by the murine AIDS (MAIDS) defective virus gag p12 gene, emulsified in incomplete Freund's adjuvant (ICFA). One week later, the mice were inoculated with the MAIDS virus to see if the immunization affects progression of ...

journal_title：Vaccine

authors： Mizuochi T,Horino A,Uchida T

更新日期：1998-12-01 00:00:00

abstract：:Dromedary camel hepatitis E virus is a novel HEV that belongs to the family Hepeviridae, and is classified as genotype 7 HEV (HEV-7). Since HEV-7 is transmitted from camels to humans and causes acute hepatitis E, this virus is a non-negligible pathogen for zoonosis, and a vaccine against HEV-7 infection is urgently ne...

journal_title：Vaccine

authors： Guo Y,Yang F,Xu X,Feng M,Liao Y,He Z,Takeda N,Muramatsu M,Li Q,Li TC

更新日期：2020-10-27 00:00:00

abstract：:Since inactivated influenza vaccines mainly confer protective immunity by inducing strain-specific antibodies to the viral hemagglutinin, these vaccines only afford protection against infection with antigenically matching influenza virus strains. Due to the continuous emergence of antigenic drift variants of seasonal ...

journal_title：Vaccine

authors： Altenburg AF,Rimmelzwaan GF,de Vries RD

更新日期：2015-01-15 00:00:00

abstract：:Protection against diseases caused by the avian viruses, Marek's disease, Infectious laryngotracheitis, chicken anemia and turkey meningoencephalitis is achieved by live vaccines. The application quality is important to assure proper uptake in commercial flocks. We describe a novel evaluation method for the vaccinatio...

journal_title：Vaccine

authors： Davidson I,Natour-Altory A,Raibstein I,Kin E,Dahan Y,Krispin H,Elkin N

更新日期：2018-01-29 00:00:00

abstract：:The potency of genetic immunization observed in the mouse has demonstrated the utility of DNA vaccines to induce cell-mediated and humoral immune responses. However, it has been relatively difficult to generate comparable responses in non-rodent species. The use of molecular adjuvants may increase the magnitude of the...

journal_title：Vaccine

authors： Maue AC,Waters WR,Palmer MV,Nonnecke BJ,Minion FC,Brown WC,Norimine J,Foote MR,Scherer CF,Estes DM

更新日期：2007-06-11 00:00:00

abstract：:Plague, which is initiated by Yersinia pestis infection, is a fatal disease that progresses rapidly and leads to high mortality rates if not treated. Antibiotics are an effective plague therapy, but antibiotic-resistant Y. pestis strains have been reported and therefore alternative countermeasures are needed. In the p...

journal_title：Vaccine

authors： Levy Y,Flashner Y,Tidhar A,Zauberman A,Aftalion M,Lazar S,Gur D,Shafferman A,Mamroud E

更新日期：2011-09-16 00:00:00

abstract：BACKGROUND:In most low and middle-income countries (LMIC), vaccines are primarily distributed by routine immunization services (RI) at health facilities. Additional opportunities for vaccination are also provided through mass vaccination campaigns, conducted periodically as part of disease-specific initiatives. It is u...

journal_title：Vaccine

authors： Helleringer S,Asuming PO,Abdelwahab J

更新日期：2016-07-19 00:00:00

abstract：:Lassa fever remains the most imported viral haemorrhagic fever in Europe and is responsible for 5000 deaths per year throughout Western Africa. There is no vaccine and treatment is often ineffective. We have developed a vaccine based on modified Vaccinia Ankara expressing the nucleoprotein from Lassa virus (MVALassaNP...

journal_title：Vaccine

authors： Kennedy EM,Dowall SD,Salguero FJ,Yeates P,Aram M,Hewson R

更新日期：2019-08-23 00:00:00