Safety evaluation of a recombinant myxoma-RHDV virus inducing horizontal transmissible protection against myxomatosis and rabbit haemorrhagic disease.

abstract：:In 2010, the Brazilian Ministry of Health organized a mass vaccination campaign of selected priority groups in response to the 2009 H1N1 influenza pandemic. The campaign was conducted in six phases from March to July, 2010. Priority groups included healthcare professionals, indigenous persons, pregnant women, young ch...

journal_title：Vaccine

authors： Domingues CM,de Oliveira WK,Brazilian Pandemic Influenza Vaccination Evaluation Team.

更新日期：2012-07-06 00:00:00

abstract：:Limited research has examined HPV vaccination in Appalachia, a region with cervical cancer disparities. We analyzed 2008-2010 National Immunization Survey-Teen data for adolescent females ages 13-17 from Appalachia (n=1951) to identify correlates of HPV vaccination and reasons why their parents do not intend to vaccin...

journal_title：Vaccine

authors： Reiter PL,Katz ML,Paskett ED

更新日期：2013-06-28 00:00:00

abstract：:Pneumococcal meningitis in the African meningitis belt is primarily caused by Streptococcus pneumoniae serotype 1, a serotype contained in the 13-valent pneumococcal conjugate vaccine (PCV13). In 2014, Niger introduced PCV13 with doses given at 6, 10, and 14 weeks of age. We leveraged existing meningitis surveillance ...

journal_title：Vaccine

authors： Ousmane S,Kobayashi M,Seidou I,Issaka B,Sharpley S,Farrar JL,Whitney CG,Ouattara M

更新日期：2020-05-13 00:00:00

abstract：:In a phase I clinical trial, one hundred healthy young adults were randomized to receive two doses 28 days apart of an inactivated, subvirion vaccine containing 15 or 45microg of influenza A/H5N1 hemagglutinin (HA) by the intramuscular (IM) route, or 3 or 9microg of H5 HA by the intradermal(ID) route. Seventy-seven su...

journal_title：Vaccine

authors： Patel SM,Atmar RL,El Sahly HM,Cate TR,Keitel WA

更新日期：2010-04-09 00:00:00

abstract：:It is generally accepted that the introduction of hepatitis B vaccine to national programmes of immunization in developing countries is desirable, but it has so far been constrained by the high cost of the vaccine. To determine the potential minimal costs of the vaccine, a study has been carried out of the production ...

journal_title：Vaccine

authors： Mahoney RT

更新日期：1990-08-01 00:00:00

abstract：:The aims of this project were: (1) to determine the extent to which infant hepatitis B immunisation is preventing chronic hepatitis B infection in children living in a sample of Pacific Island countries; and (2) to identify factors associated with the successful prevention of hepatitis B infection in these populations...

journal_title：Vaccine

authors： Wilson N,Ruff TA,Rana BJ,Leydon J,Locarnini S

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:In 2013, pertussis immunization (Tdap) for pregnant women was implemented in Colombia to protect newborns in response to increased pertussis incidence. OBJECTIVE:To assess the effect of Tdap maternal immunization on the concentration of mother/umbilical cord antibodies and the occurrence of pertussis in inf...

journal_title：Vaccine

authors： Hincapié-Palacio D,Hoyos MC,Ochoa J,Montoya N,García D,Osorio E,Pertussis Working Group.

更新日期：2018-06-22 00:00:00

abstract：:Cattle produce specific serum antibody mainly of the IgG1 isotype in response to infection with the liver fluke, Fasciola hepatica. In these animals a positive correlation between fluke-specific serum IgG1 levels and fluke-burden in non-immunized infected animals was observed. In contrast, immunization of cattle with ...

journal_title：Vaccine

authors： Mulcahy G,O'Connor F,McGonigle S,Dowd A,Clery DG,Andrews SJ,Dalton JP

更新日期：1998-05-01 00:00:00

abstract：:The most common preventative measure against mumps is vaccination with mumps vaccine. In most parts of the world, mumps vaccine is routinely delivered through live attenuated Measles-Mumps-Rubella (MMR) vaccine. In Japan, receiving mumps vaccine is voluntary and vaccine uptake rate is less than 30%. The introduction o...

journal_title：Vaccine

authors： Hoshi SL,Kondo M,Okubo I

更新日期：2014-07-16 00:00:00

abstract：:Live cold-adapted recombinant bivalent vaccine of influenza type A was studied in a controlled field trial in 1982-1983 among nearly 30,000 children 3-15 years old. The bivalent vaccine consisted of recombinants 47/25/1 (H1N1) and 47/7/2 (H3N2) of wild-type viruses A/Brazil/11/78 (H1N1) and A/Bangkok/1/79 (H3N2) with ...

journal_title：Vaccine

authors： Alexandrova GI,Budilovsky GN,Koval TA,Polezhaev FI,Garmashova LM,Ghendon YuZ,Romanova YR,Smorodintsev AA

更新日期：1986-06-01 00:00:00

abstract：:We investigated whether a combined DNA vaccine delivered together with the IL-15 gene (DNA-IL-15(+)) enhanced the immune response against Brucella abortus in mice. Mice vaccinated with DNA-IL-15(+) developed a robust humoral response; Brucella-specific antibodies exhibited a dominance of immunoglobulin G2a (IgG2a) ove...

journal_title：Vaccine

authors： Hu XD,Chen ST,Li JY,Yu DH,Yi-Zhang,Cai H

更新日期：2010-03-11 00:00:00

abstract：:We describe here the preclinical development of a dengue vaccine composed of recombinant subunit carboxy-truncated envelope (E) proteins (DEN-80E) for each of the four dengue serotypes. Immunogenicity and protective efficacy studies in Rhesus monkeys were conducted to evaluate monovalent and tetravalent DEN-80E vaccin...

journal_title：Vaccine

authors： Govindarajan D,Meschino S,Guan L,Clements DE,ter Meulen JH,Casimiro DR,Coller BA,Bett AJ

更新日期：2015-08-07 00:00:00

abstract：OBJECTIVE:Evidence-based strategies to address vaccine hesitancy are lacking. Personal values are a measurable psychological construct that could be used to deliver personalized messages to influence vaccine hesitancy and behavior. Our objectives were to develop a valid, reliable self-report survey instrument to measur...

journal_title：Vaccine

authors： Cataldi JR,Sevick C,Pyrzanowski J,Wagner N,Brewer SE,Narwaney KJ,Shoup JA,Resnicow K,Glanz J,Dempsey A,Kwan BM

更新日期：2019-09-10 00:00:00

abstract：:Protection against Schistosoma mansoni infection in C57BL/6 female mice was evaluated by two DNA vaccination strategies. Mice were either vaccinated by intramuscular injection with pcDNAI/Amp constructs encoding either Cu/Zn cytosolic superoxide dismutase (CT-SOD), signal peptide-containing SOD (SP-SOD), glutathione p...

journal_title：Vaccine

authors： Shalaby KA,Yin L,Thakur A,Christen L,Niles EG,LoVerde PT

更新日期：2003-12-08 00:00:00

abstract：:Estimation of the full disease burden caused by Streptococcus pneumoniae is challenging due to the difficulties in assigning the aetiology especially in lower and upper respiratory infections. We estimated the pneumococcal disease burden by using the vaccine-preventable disease incidence (VPDI) of PHiD-CV10 vaccine (G...

journal_title：Vaccine

authors： Palmu AA,Jokinen J,Nieminen H,Rinta-Kokko H,Ruokokoski E,Puumalainen T,Moreira M,Schuerman L,Borys D,Kilpi TM

更新日期：2018-03-27 00:00:00

abstract：:Establishing successful vaccine programs for pregnant women would be the quintessence of preventive medicine when you realize the preventive potential for reproductive problems of many of the new and old vaccines. The development of vaccines to prevent maternal, fetal and newborn disease is actually in its infancy. Th...

journal_title：Vaccine

authors： Brent RL

更新日期：2003-07-28 00:00:00

abstract：BACKGROUND:Combination highly active antiretroviral therapy (HAART) has significantly decreased HIV-1 related morbidity and mortality globally transforming HIV into a controllable condition. HAART has a number of limitations though, including limited access in resource constrained countries, which have driven the searc...

journal_title：Vaccine

authors： Vardas E,Stanescu I,Leinonen M,Ellefsen K,Pantaleo G,Valtavaara M,Ustav M,Reijonen K

更新日期：2012-06-08 00:00:00

abstract：:In this proof-of-concept study we report the use of <15 nm, water soluble, inorganic nanoparticles as a vaccine delivery system for a blood stage malaria vaccine. The recombinant malarial antigen, Merozoite Surface Protein 1 (rMSP1) of Plasmodium falciparum served as the model vaccine. The rMSP1 was covalently conjuga...

journal_title：Vaccine

authors： Pusic K,Xu H,Stridiron A,Aguilar Z,Wang A,Hui G

更新日期：2011-11-08 00:00:00

abstract：:The United States Advisory Committee on Immunization Practices (ACIP) is a federal advisory committee that develops written recommendations for use of vaccines licensed by the Food and Drug Administration (FDA) for the U.S. civilian population. Vaccine development and disease outbreaks contributed to the need for a sy...

journal_title：Vaccine

authors： Walton LR,Orenstein WA,Pickering LK

更新日期：2015-01-09 00:00:00

abstract：BACKGROUND:Measles-containing vaccine (MCV) was introduced in 1965 in Beijing and given to the children aged 8m-14y. In population-based surveillance system, real-time polymerase chain reaction (RT-PCR) and immunoglobulin M(IgM) serology tests have been conducted for each suspected case since 2013. We used the surveill...

journal_title：Vaccine

authors： Ma R,Lu L,Suo L,Zhangzhu J,Chen M,Pang X

更新日期：2019-06-27 00:00:00

abstract：:The first 4 years of the 21st century have been an exciting time for tuberculosis (TB) research. After more than a half-century, the first new vaccines for TB are beginning to enter human clinical trials. Based on advances in proteomics and genomics, new vaccine candidates are filling the preclinical pipeline and our ...

journal_title：Vaccine

authors： Doherty TM

更新日期：2005-03-18 00:00:00

abstract：:The prevalence of hepatitis B virus (HBV) infection and its sequelae vary widely in the different populations living in the Asian-Pacific region. Horizontal transmission plays an important role in the spread of the disease; in East Asia, however, maternal transmission is particularly significant since a high portion o...

journal_title：Vaccine

authors： Sung JL

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Pseudotuberculosis is an infection caused by the bacterial enteropathogen Yersinia pseudotuberculosis and is considered to be a significant problem in veterinary medicine. We previously found that intranasal administration of a recombinant Lactococcus lactis strain that secretes the low-calcium response V (L...

journal_title：Vaccine

authors： Daniel C,Titecat M,Poiret S,Cayet D,Boutillier D,Simonet M,Sirard JC,Lemaître N,Sebbane F

更新日期：2016-11-11 00:00:00

abstract：:A flow cytometry-based assay was developed to assess the infective titer of two recombinant viruses: a recombinant herpes simplex type 2 (rHSV-2) and a recombinant canary pox (rALVAC.gfp). This method uses granularity of infected Vero and QT-35 cells, respectively, and correlates this to the infectious titer of virus ...

journal_title：Vaccine

authors： Logan M,Manalil J,Notte C,Kearse C,George S,Zeiser A,Farrell P,Aucoin MG

更新日期：2019-11-08 00:00:00

abstract：:Four different preparations of hepatitis B antigen (HBsAg) were tested in parallel with respect to their ability to elicit anti-HBs in guinea-pigs. We compared the effect of low doses (5 micrograms single dose and 30 micrograms total amount) of human plasma derived and recombinant HBsAg, in purified forms or prepared ...

journal_title：Vaccine

authors： Valinger Z,Tresćec A,Tomasić J

更新日期：1990-12-01 00:00:00

abstract：:Cellular as well as humoral immune reactivity were studied in healthy young (< 30 years; n = 12) and older (> 65 years; n = 12) individuals before as well as 1 month after immunization with a trivalent whole virus influenza vaccine. Before vaccination, peripheral blood mononuclear cell proliferation in response to in ...

journal_title：Vaccine

authors： Saurwein-Teissl M,Steger MM,Glück R,Cryz S,Grubeck-Loebenstein B

更新日期：1998-01-01 00:00:00

abstract：:Serum specimens of 1075 young adults representing nursing and medical staff were collected for determination of rubella immunity using the radial haemolysis (RH) technique, also know as the haemolysis in gel (HIG) test. Of the sera 84 (7.8%) were negative (RH titre less than 4 mm) and an additional 93 (8.7%) gave an R...

journal_title：Vaccine

authors： Väänänen P,Mäkelä P,Vaheri A

更新日期：1986-03-01 00:00:00

abstract：:In HIV vaccine trials, the collection and analysis of participant behavior data associated with risk of acquiring HIV-infection is important for a number of reasons. Although the rationale for behavioral risk assessment in HIV vaccine clinical trials is clear, consistent collection of behavioral data over time and acr...

journal_title：Vaccine

authors： Andrasik MP,Karuna ST,Nebergall M,Koblin BA,Kublin JG,NIAID HIV Vaccine Trials Network.

更新日期：2013-09-13 00:00:00

abstract：:Human intestinal infections with the nematode Strongyloides stercoralis remain a significant problem worldwide and a vaccine would be a useful addition to the tools available to prevent and control this infection. The goal of this study was to test single antigens for their efficacy in a vaccine against S. stercoralis...

journal_title：Vaccine

authors： Abraham D,Hess JA,Mejia R,Nolan TJ,Lok JB,Lustigman S,Nutman TB

更新日期：2011-10-19 00:00:00

abstract：:Strains of Newcastle disease virus (NDV) can be separated into genotypes based on genome differences even though they are antigenically considered to be of a single serotype. It is widely recognized that an efficacious Newcastle disease (ND) vaccine made with any NDV does induce protection against morbidity and mortal...

journal_title：Vaccine

authors： Miller PJ,King DJ,Afonso CL,Suarez DL

更新日期：2007-10-10 00:00:00