Effect of low level immunity on response to live rubella virus vaccine.

abstract：:These studies were performed to determine the effects of GPI-0100, a semi synthetic Quillaja Saponin analog, formulated with herpes simplex virus type-1 (HSV-1) glycoprotein D (gD) on immunity to HSV. SKH-1 hairless mice, used as a model of herpes labialis, inoculated with HSV-1 results in facial lesions, virus replic...

journal_title：Vaccine

authors： Quenelle DC,Collins DJ,Marciani DJ,Kern ER

更新日期：2006-03-06 00:00:00

abstract：OBJECTIVE:To determine if the addition of a physician peer educator would lead to improved immunization quality when compared to the traditional education provided as part of a vaccines for children (VFC) site visit. METHODS:A randomized controlled trial was conducted. Study participants were private pediatric and fam...

journal_title：Vaccine

authors： Taylor JA,Rietberg K,Greenfield L,Bibus D,Yasuda K,Marcuse EK,Duchin JS

更新日期：2008-08-05 00:00:00

abstract：:Respiratory syncytial virus (RSV) is the most common cause of viral bronchiolitis and pneumonia in children. The present study compares the level of attenuation, genetic stability and efficacy of three conditional-lethal temperature-sensitive (ts) mutants of the RSV A2 wild-type virus, designated ts-1, ts-1-NG1, and t...

journal_title：Vaccine

authors： Crowe JE Jr,Collins PL,London WT,Chanock RM,Murphy BR

更新日期：1993-11-01 00:00:00

abstract：INTRODUCTION:The recent emergence of avian influenza strains has fuelled concern about pandemic preparedness since vaccines targeting these viruses are often poorly immunogenic. Weak antibody responses to vaccines have been seen across multiple platforms including plant-made VLPs. To better understand these differences...

journal_title：Vaccine

authors： Hendin HE,Pillet S,Lara AN,Wu CY,Charland N,Landry N,Ward BJ

更新日期：2017-05-02 00:00:00

abstract：:Since the introduction to the Swiss market in 1997, Crucell (former Berna Biotech Ltd.), has sold over 41 million doses worldwide of the virosomal adjuvanted influenza vaccine, Inflexal V. Since 1992, 29 company sponsored clinical studies investigating the efficacy and safety of Inflexal V have been completed in which...

journal_title：Vaccine

authors： Herzog C,Hartmann K,Künzi V,Kürsteiner O,Mischler R,Lazar H,Glück R

更新日期：2009-07-16 00:00:00

abstract：OBJECTIVE:Monitor the long-term immunogenicity of a single dose of acellular pertussis vaccine in health-care workers. DESIGN:German health-care workers and child-care workers received a single dose of a monovalent acellular pertussis vaccine (PAC-Mérieux) in an open-label study. Blood samples were taken before (n=261...

journal_title：Vaccine

authors： Littmann M,Hülsse C,Riffelmann M,Wirsing von König CH

更新日期：2008-05-02 00:00:00

abstract：:The purpose of this study was to investigate the utility of various in vitro and in vivo methods to assess the stability of experimental vaccines containing tetanus toxoid (TT) within PLGA microspheres. In vitro, the breakdown of the encapsulating polymers into their acid components led to changes in the structure of ...

journal_title：Vaccine

authors： Sasiak AB,Bolgiano B,Crane DT,Hockley DJ,Corbel MJ,Sesardic D

更新日期：2000-11-22 00:00:00

abstract：:A phase III, randomized, double-blind study evaluated the efficacy, reactogenicity, safety and immunogenicity of a human rotavirus vaccine, RIX4414 in Japanese infants aged 6-14 weeks when administered as two doses (0, 1-month schedule). Efficacy against any and severe rotavirus gastroenteritis leading to medical inte...

journal_title：Vaccine

authors： Kawamura N,Tokoeda Y,Oshima M,Okahata H,Tsutsumi H,Van Doorn LJ,Muto H,Smolenov I,Suryakiran PV,Han HH

更新日期：2011-08-26 00:00:00

abstract：:Oral polio vaccine (OPV) and diphtheria-tetanus-pertussis (DTP) vaccines are given simultaneously in routine immunisation programmes in developing countries. It is therefore difficult to determine the separate effects of these vaccines on survival. We used the shortage of DTP vaccine in Bissau to examine the impact of...

journal_title：Vaccine

authors： Aaby P,Rodrigues A,Biai S,Martins C,Veirum JE,Benn CS,Jensen H

更新日期：2004-08-13 00:00:00

abstract：:We previously demonstrated that recombinant raccoonpox (RCN) virus could serve as a vector for an influenza vaccine. RCN constructs expressing the hemagglutinin (HA) from H5N1 viruses were immunogenic in chickens. In the current study, we generated several recombinant RCN constructs expressing influenza (H5N1) antigen...

journal_title：Vaccine

authors： Kingstad-Bakke B,Brewoo JN,Mai le Q,Kawaoka Y,Osorio JE

更新日期：2012-10-05 00:00:00

abstract：:Three recombinant strains of Mycobacterium bovis Bacille Calmette Guerin (rBCG) were prepared in which the immunogenic B subunit of human Escherichia coli heat labile enterotoxin (LT-Bh) was expressed either as a cytoplasm protein, a cell wall associated lipoprotein or a secreted protein. Intraperitoneal immunisation ...

journal_title：Vaccine

authors： Hayward CM,O'Gaora P,Young DB,Griffin GE,Thole J,Hirst TR,Castello-Branco LR,Lewis DJ

更新日期：1999-03-05 00:00:00

abstract：:Increasing mortality, morbidity and economic costs have been paid to pneumococcal diseases every year. Currently, vaccination is the most promising strategy to reduce the occurrence of pneumococcal infection. In this study, we investigated the protective efficacy of immunization with recombinant DnaJ (hsp40) protein a...

journal_title：Vaccine

authors： Cui Y,Zhang X,Gong Y,Niu S,Yin N,Yao R,Xu W,Li D,Wang H,He Y,Cao J,Yin Y

更新日期：2011-02-17 00:00:00

abstract：BACKGROUND:The combined hexavalent diphtheria-tetanus-pertussis-hepatitis B-inactivated poliomyelitis - Haemophilus influenzae type b conjugate vaccine (Infanrix hexa™; DTPa-HBV-IPV/Hib: GlaxoSmithKline Vaccines) induces robust responses to the HBV component when administered at 3, 5 and 11-12 months of age. We assesse...

journal_title：Vaccine

authors： Avdicova M,Crasta PD,Hardt K,Kovac M

更新日期：2015-05-28 00:00:00

abstract：:Rotavirus (RV) is the primary etiologic agent of severe gastroenteritis in human infants. Although two attenuated RV-based vaccines have been licensed to be applied worldwide, they are not so effective in low-income countries, and the induced protection mechanisms have not been clearly established. Thus, it is importa...

journal_title：Vaccine

authors： Badillo-Godinez O,Gutierrez-Xicotencatl L,Plett-Torres T,Pedroza-Saavedra A,Gonzalez-Jaimes A,Chihu-Amparan L,Maldonado-Gama M,Espino-Solis G,Bonifaz LC,Esquivel-Guadarrama F

更新日期：2015-08-20 00:00:00

abstract：:Therapeutic immunization of HIV-1-infected individuals with or without anti-retroviral therapy is a new promising disease prevention. To induce a new cytotoxic T(CD8) lymphocyte (CTL) immunity during chronic HIV-1 infection 15 infrequently targeted but conserved HLA-supertype binding CTL epitopes from Gag, Pol, Nef, E...

journal_title：Vaccine

authors： Fomsgaard A,Karlsson I,Gram G,Schou C,Tang S,Bang P,Kromann I,Andersen P,Andreasen LV

更新日期：2011-09-16 00:00:00

abstract：:Two cyclic peptide analogues corresponding to residues 139-146 (site A) of influenza A virus haemagglutinin (strain X31) were synthesized. The ability of these peptides to react with anti-influenza virus antibodies was found to depend on the conformation of the loop and on the orientation in which the peptide was pres...

journal_title：Vaccine

authors： Muller S,Plaué S,Samama JP,Valette M,Briand JP,Van Regenmortel MH

更新日期：1990-08-01 00:00:00

abstract：:Influenza virus causes acute upper and lower respiratory infections and is the most likely, among known pathogens, to cause a large epidemic in humans. Influenza virus mutates rapidly, enabling it to evade natural and vaccine-induced immunity. Furthermore, influenza viruses can cross from animals to humans, generating...

journal_title：Vaccine

authors： Berlanda Scorza F,Tsvetnitsky V,Donnelly JJ

更新日期：2016-06-03 00:00:00

abstract：:In the present study the efficacy of recombinant plasmids DNA vaccine encoding VP2 gene of very virulent strain of infectious bursal disease virus (vvIBDV) isolated from Pakistan was investigated with or without coadministration of cytocine-phosphate-guanine oligodeoxynucleotide (CpG ODN) to protect the chickens again...

journal_title：Vaccine

authors： Mahmood MS,Siddique M,Hussain I,Khan A,Mansoor MK

更新日期：2006-05-29 00:00:00

abstract：:The costs of developing and producing new-generation vaccines have increased compared to many of the older, "traditional" vaccines because of new technologies and regulatory requirements. While the public sector often supports basic research costs, private manufacturers are usually responsible for the investments in p...

journal_title：Vaccine

authors： Batson A,Meheus F,Brooke S

更新日期：2006-08-31 00:00:00

abstract：:Delayed-type hypersensitivity (DTH) response to arthropod vector salivary proteins is associated with protection against pathogen transmission. Massive cDNA sequencing, high-throughput DNA plasmid construction and DNA immunisation were used to identify twelve DTH inducing proteins isolated from a Phlebotomus ariasi sa...

journal_title：Vaccine

authors： Oliveira F,Kamhawi S,Seitz AE,Pham VM,Guigal PM,Fischer L,Ward J,Valenzuela JG

更新日期：2006-01-16 00:00:00

abstract：:We report influenza vaccination coverage in target groups for the 2010-2011 influenza season, one year after the A(H1N1) pandemic. Data were collected through a one-stage cross-sectional national random telephone survey conducted in January 2011 among a sample of the population of mainland France connected to a land t...

journal_title：Vaccine

authors： Guthmann JP,Fonteneau L,Bonmarin I,Lévy-Bruhl D

更新日期：2012-02-01 00:00:00

abstract：:A small number of serotypes are responsible for most invasive pneumococcal disease in children worldwide. Serotypes 1 and 5 were among the first pneumococcal serotypes to be identified, reflecting their great prominence as causes of disease in the early part of the 20th century. In the antibiotic era, these serotypes ...

journal_title：Vaccine

authors： Hausdorff WP

更新日期：2007-03-22 00:00:00

abstract：:We exploited the powerful adjuvant properties of cholera holotoxin (CT) to create a mucosally administered subunit vaccine against respiratory syncytial virus (RSV). A genetically detoxified mutant CT with an E to H substitution at amino acid 29 of the CT-A1 subunit (CT-E29H) was compared to wild type CT for toxicity ...

journal_title：Vaccine

authors： Tebbey PW,Scheuer CA,Peek JA,Zhu D,LaPierre NA,Green BA,Phillips ED,Ibraghimov AR,Eldridge JH,Hancock GE

更新日期：2000-06-01 00:00:00

abstract：:Current infant vaccination against pertussis in North America and Australia requires three doses of vaccines including diphtheria, tetanus and acellular pertussis antigens (DTaP) at 2, 4 and 6 months of age. Interest is growing in the possibility that vaccination at birth might provide earlier protection of infants, b...

journal_title：Vaccine

authors： White OJ,Rowe J,Richmond P,Marshall H,McIntyre P,Wood N,Holt PG

更新日期：2010-03-19 00:00:00

abstract：QUESTION UNDER STUDY:To investigate the persistence of maternal IgG antibodies against Varicella-Zoster virus (VZV) in infants and young children. METHODS:Serum specimens of children aged 0-16 months who had been hospitalized in our institution between 1994 and 1999 were identified from our routine serum collection. E...

journal_title：Vaccine

authors： Heininger U,Desgrandchamps D,Schaad UB

更新日期：2006-04-12 00:00:00

abstract：:Mumps virus (MuV) causes acute infection in humans with characteristic swelling of the parotid gland. While vaccination has greatly reduced the incidence of MuV infection, there have been multiple large outbreaks of mumps virus (MuV) in highly vaccinated populations. The most common vaccine strain, Jeryl Lynn, belongs...

journal_title：Vaccine

authors： Zengel J,Phan SI,Pickar A,Xu P,He B

更新日期：2017-07-13 00:00:00

abstract：:A formulation of recombinant hepatitis B surface antigen (HBsAg) combined with a novel adjuvant system, SBAS4--a combination of aluminium salt and monophosphoryl lipid A (MPL), was assessed in 27 healthy adult volunteers with a commercial vaccine (Engerix-B) as control. After three doses (0, 1, 6 months schedule), rea...

journal_title：Vaccine

authors： Thoelen S,Van Damme P,Mathei C,Leroux-Roels G,Desombere I,Safary A,Vandepapeliere P,Slaoui M,Meheus A

更新日期：1998-04-01 00:00:00

abstract：:Seasonal influenza epidemics are associated with high morbidity and mortality particularly in high-risk patients. Conventionally administered influenza vaccines show reduced efficacy in populations with weakened immune systems such as solid-organ transplant patients. This study assesses the safety and immunogenicity o...

journal_title：Vaccine

authors： Morelon E,Pouteil Noble C,Daoud S,Cahen R,Goujon-Henry C,Weber F,Laurent PE,Kaiserlian D,Nicolas JF

更新日期：2010-10-04 00:00:00

abstract：BACKGROUND:US-bound refugees undergo required health assessments overseas to identify and treat communicable diseases of public health significance-such as pulmonary tuberculosis-before migration. Immunizations are not required, leaving refugees at risk for vaccine-preventable diseases. In response, the US Centers for ...

journal_title：Vaccine

authors： Mitchell T,Dalal W,Klosovsky A,Yen C,Phares C,Burkhardt M,Amin F,Froes I,Hamadeh A,Lynn SA,Quintanilla J,Doney AC,Cetron M,Weinberg M

更新日期：2021-01-03 00:00:00

abstract：:Information provided by most influenza vaccine manufacturers do not reflect the recommendations of WHO and/or national public health advisory groups with regard to the use of influenza vaccines in pregnant or lactating women. The majority of vaccines contain precautionary language which could discourage use in pregnan...

journal_title：Vaccine

authors： Proveaux T,Lambach P,Ortiz JR,Hombach J,Halsey NA

更新日期：2016-10-26 00:00:00