Hepatitis B virus eradication strategy for Asia. The Asian Regional Study Group.

Abstract:

:The prevalence of hepatitis B virus (HBV) infection and its sequelae vary widely in the different populations living in the Asian-Pacific region. Horizontal transmission plays an important role in the spread of the disease; in East Asia, however, maternal transmission is particularly significant since a high portion of infected infants become chronic carriers and develop cirrhosis and hepatocellular carcinoma later in life. Cost-benefit studies performed in Taipei and Shanghai show that hepatitis B vaccination is cost-effective. The three main strategies for HBV eradication include universal immunization or active plus passive immunization in areas of high endemicity, and selective vaccination of high-risk groups where carriage of the surface antigen is low.

journal_name

Vaccine

journal_title

Vaccine

authors

Sung JL

doi

10.1016/0264-410x(90)90227-d

subject

Has Abstract

pub_date

1990-03-01 00:00:00

pages

S95-9

eissn

0264-410X

issn

1873-2518

pii

0264-410X(90)90227-D

journal_volume

8 Suppl

pub_type

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