Abstract:
:The prevalence of hepatitis B virus (HBV) infection and its sequelae vary widely in the different populations living in the Asian-Pacific region. Horizontal transmission plays an important role in the spread of the disease; in East Asia, however, maternal transmission is particularly significant since a high portion of infected infants become chronic carriers and develop cirrhosis and hepatocellular carcinoma later in life. Cost-benefit studies performed in Taipei and Shanghai show that hepatitis B vaccination is cost-effective. The three main strategies for HBV eradication include universal immunization or active plus passive immunization in areas of high endemicity, and selective vaccination of high-risk groups where carriage of the surface antigen is low.
journal_name
Vaccinejournal_title
Vaccineauthors
Sung JLdoi
10.1016/0264-410x(90)90227-dsubject
Has Abstractpub_date
1990-03-01 00:00:00pages
S95-9eissn
0264-410Xissn
1873-2518pii
0264-410X(90)90227-Djournal_volume
8 Supplpub_type
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