Detection of measles vaccine in the throat of a vaccinated child.

abstract：:Rift Valley fever virus (RVFV), a member of the family Bunyaviridae, causes severe to fatal disease in newborn ruminants, as well as abortions in pregnant animals; both preventable by vaccination. Availability of a challenge model is a pre-requisite for vaccine efficacy trials. Several modes of inoculation with RVFV Z...

journal_title：Vaccine

authors： Weingartl HM,Miller M,Nfon C,Wilson WC

更新日期：2014-04-25 00:00:00

abstract：:Current infant vaccination against pertussis in North America and Australia requires three doses of vaccines including diphtheria, tetanus and acellular pertussis antigens (DTaP) at 2, 4 and 6 months of age. Interest is growing in the possibility that vaccination at birth might provide earlier protection of infants, b...

journal_title：Vaccine

authors： White OJ,Rowe J,Richmond P,Marshall H,McIntyre P,Wood N,Holt PG

更新日期：2010-03-19 00:00:00

abstract：:In order to establish a firm preventive measure for tick-borne encephalitis (TBE) in Japan, we evaluated the immune response of European vaccine against Japanese TBE virus strain (Oshima 5-10) for man and mouse. Furthermore, the efficacy of pre- and post-exposure protection by a polyclonal rabbit anti-TBE virus serum ...

journal_title：Vaccine

authors： Chiba N,Osada M,Komoro K,Mizutani T,Kariwa H,Takashima I

更新日期：1999-03-17 00:00:00

abstract：:Streptococcus pneumoniae is the leading cause of bacterial pneumonia, meningitis and sepsis in children worldwide. Despite available evidence on pneumococcal conjugate vaccine (PCV) impact on pneumonia hospitalizations in children, studies demonstrating PCV impact in morbidity and mortality in middle-income countries ...

journal_title：Vaccine

authors： Suarez V,Michel F,Toscano CM,Bierrenbach AL,Gonzales M,Alencar AP,Ruiz Matus C,Andrus JK,de Oliveira LH

更新日期：2016-09-07 00:00:00

abstract：:The immunogenicity of two vector-based vaccines, either given alone or in a prime-boost regimen, was investigated. Cynomolgus macaques were immunised with modified vaccinia virus Ankara (MVA) expressing simian immunodeficiency virus (SIV)macJ5 env, gag-pol, nef, rev, and tat genes (MVA-SIVmac) or primed with a Semliki...

journal_title：Vaccine

authors： Nilsson C,Mäkitalo B,Berglund P,Bex F,Liljeström P,Sutter G,Erfle V,ten Haaft P,Heeney J,Biberfeld G,Thorstensson R

更新日期：2001-05-14 00:00:00

abstract：:Like any biotechnology innovation, the production of human vaccines in plants will succeed partly on its technical merits, and partly on the social acceptance of the new technology. The latter is harder to predict than the former, and may pose the most significant challenges to plant-derived vaccines' (PDVs) success. ...

journal_title：Vaccine

authors： Castle D,Dalgleish J

更新日期：2005-03-07 00:00:00

abstract：BACKGROUND:Germany introduced routine varicella (V) vaccination in 2004. Due to a slightly increased risk of febrile convulsions after first-dose application of combined measles-mumps-rubella-varicella (MMRV) vaccine separate first-dose vaccinations with MMR and monovalent V vaccine were recommended in September 2011. ...

journal_title：Vaccine

authors： Streng A,Liese JG

更新日期：2014-02-12 00:00:00

abstract：:To determine the potential for biodegradable alginate microspheres to be used as a delivery vehicle for DNA based vaccines, we constructed a plasmid, pMNe-gal-SV40, containing the bacterial beta-galactosidase (LacZ) gene under the control of the murine cytomegalovirus (MCMV) immediate-early promoter and the simian vir...

journal_title：Vaccine

authors： Mittal SK,Aggarwal N,Sailaja G,van Olphen A,HogenEsch H,North A,Hays J,Moffatt S

更新日期：2000-09-15 00:00:00

abstract：BACKGROUND:Tuberculosis is a major challenge for health care, as options for its treatment and prevention are limited. Therefore, novel approaches, such as DNA vaccination, to both prevent primary infections and the reactivation of latent infections need to be developed. A Mycobacterium marinum infection in adult zebra...

journal_title：Vaccine

authors： Niskanen M,Myllymäki H,Rämet M

更新日期：2020-07-31 00:00:00

abstract：:After massive epidemics of bluetongue disease in 2006 and 2007, Germany has started a compulsory vaccination program against bluetongue virus serotype 8 (BTV-8). Since the available vaccines had not yet been registered and only limited data were available on their performance, a safety study was conducted with three d...

journal_title：Vaccine

authors： Gethmann J,Hüttner K,Heyne H,Probst C,Ziller M,Beer M,Hoffmann B,Mettenleiter TC,Conraths FJ

更新日期：2009-06-24 00:00:00

abstract：:An Madin-Darby canine kidney (MDCK) cell line, 9B9-1E4, was cloned by limit dilution from a heterologous cell population and chosen as a potential production cell substrate for cell culture-based influenza vaccine manufacture. Since MDCK cells are transformed cells of canine origin, extensive characterization, includi...

journal_title：Vaccine

authors： Liu J,Mani S,Schwartz R,Richman L,Tabor DE

更新日期：2010-02-03 00:00:00

abstract：:In order to evaluate a combination of yellow fever and typhoid fever vaccine, we conducted a controlled trial comparing reactogenicity and immunogenicity of Vi polysaccharide (ViPS) vaccine and yellow fever 17D (YF) vaccine after single, simultaneous and combined administration. The combined YF/ViPS vaccine was prepar...

journal_title：Vaccine

authors： Ambrosch F,Fritzell B,Gregor J,Jonas S,Kollaritsch H,Teulieres L,Wiedermann G

更新日期：1994-05-01 00:00:00

abstract：:A randomized, double-blind trial comparing a diphtheria-tetanus-acellular pertussis vaccine (DTaP) (pertussis toxoid and filamentous hemagglutinin) with a whole-cell vaccine (DTwP) was conducted. A case-contact study was nested in the trial to estimate absolute efficacy. From 1990 through 1994, 4181 children were rand...

journal_title：Vaccine

authors： Simondon F,Preziosi MP,Yam A,Kane CT,Chabirand L,Iteman I,Sanden G,Mboup S,Hoffenbach A,Knudsen K,Guiso N,Wassilak S,Cadoz M

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Human papillomavirus (HPV) vaccination offers potential for primary prevention of HPV-related pre-cancers and cancers as demonstrated in clinical trials. Mathematical models have estimated the potential real-life impact of vaccination on the burden of cervical cancer (CC). However, these are restricted to ev...

journal_title：Vaccine

authors： Van Kriekinge G,Castellsagué X,Cibula D,Demarteau N

更新日期：2014-02-03 00:00:00

abstract：:The PEDVAC study is the first trial designed to analyze safety and immunogenicity of a therapeutic vaccination with a multiclade multigene HIV DNA vaccine (HIVIS) in infected children. Twenty HIV-1 vertically infected children (6-16 years of age), on stable antiretroviral treatment for at least 6 months with HIV-1 RNA...

journal_title：Vaccine

authors： Palma P,Romiti ML,Li Pira G,Montesano C,Mora N,Aquilani A,Santilli V,Tchidjou HK,Ivaldi F,Giovannelli L,Pontrelli G,Borra G,Blomberg P,Gudmundsdotter L,Bråve A,Montano M,Bernardi S,Manca F,Wahren B,Rossi P

更新日期：2011-09-09 00:00:00

abstract：:WHO is now celebrating more than 30 years of freedom from smallpox. What was originally seen as a victory over an ancient scourge can now be viewed as an epidemiologically driven programme to overcome governmental inertia and under-achievement in delivering an off-patent vaccine. Though efforts are accelerating global...

journal_title：Vaccine

authors： Music S

更新日期：2010-01-22 00:00:00

abstract：:The immunogenicity of 23-valent pneumococcal polysaccharide vaccine was assessed in 57 HIV-1 infected former intravenous drug users and in 20 HIV-1 negative controls. The effect of vaccination on HIV-1 infection was studied in a subgroup of 38 patients, 60% of whom under highly active antiretroviral therapy (HAART). A...

journal_title：Vaccine

authors： Amendola A,Tanzi E,Zappa A,Colzani D,Boschini A,Musher DM,Zanetti AR

更新日期：2002-11-01 00:00:00

abstract：:A soluble fraction obtained from Bordetella pertussis was evaluated as adjuvant for the pertussis component of the Diphtheria-Pertussis-Tetanus (DPT) vaccine. High levels of antibodies were induced, and a 78% protection rate of mice challenged with live B. pertussis was observed. Two proteins were identified as the 73...

journal_title：Vaccine

authors： Cainelli Gebara VC,Risoléo L,Lopes AP,Ferreira VR,Quintilio W,Lépine F,Silva WD,Raw I

更新日期：2007-01-08 00:00:00

abstract：:We have developed the Mycobacterium tuberculosis (Mtb) fusion protein (ID83), which contains the three Mtb proteins Rv1813, Rv3620 and Rv2608. We evaluated the immunogenicity and protective efficacy of ID83 in combination with several emulsion-formulated toll-like receptor agonists. The ID83 subunit vaccines containin...

journal_title：Vaccine

authors： Baldwin SL,Bertholet S,Kahn M,Zharkikh I,Ireton GC,Vedvick TS,Reed SG,Coler RN

更新日期：2009-05-18 00:00:00

abstract：:To evaluate the immunogenicity of 23-valent pneumococcal polysaccharide vaccine in 52 nursing homes residents aged > or = 60 years, IgG antibodies to serotypes 1, 5, 6B, and 8 were measured by ELISA and compared before, and 1 and 12 months following vaccination. A significant immunological response for all serotypes w...

journal_title：Vaccine

authors： Brandão AP,de Oliveira TC,de Cunto Brandileone MC,Gonçalves JE,Yara TI,Simonsen V

更新日期：2004-12-21 00:00:00

abstract：:Vaccine safety fears following media reports of adverse events led to low (50.3%) coverage in a supplementary measles-rubella immunization campaign in Georgia in 2008. Review of adverse events associated with the campaign identified 432 reports (<0.1% of ∼ 493,000 vaccinees) including 338 (78.2%) cases of syncope. The...

journal_title：Vaccine

authors： Khetsuriani N,Imnadze P,Baidoshvili L,Jabidze L,Tatishili N,Kurtsikashvili G,Lezhava T,Laurent E,Martin R

更新日期：2010-09-07 00:00:00

abstract：:We report the results of the handsearch of all the issues of Vaccine from 1983 to 1994 to identify randomized and controlled clinical trials (RCTs and CCTs) with the aim of setting up a Cochrane data base of vaccine trials. We read 1119 original papers and located 231 trials of which 117 (50.6%) were RCTs and 114 (49....

journal_title：Vaccine

authors： Jefferson T,Jefferson V

更新日期：1996-04-01 00:00:00

abstract：:Respiratory syncytial virus F-protein (RSV-F) is poorly expressed from DNA expression plasmids containing the wild type RSV-F open reading frame. By codon optimization, premature polyadenylation signals were deleted and a striking enhancement of RSV-F expression levels was achieved. Therefore, the immunogenicity and e...

journal_title：Vaccine

authors： Ternette N,Tippler B,Uberla K,Grunwald T

更新日期：2007-10-10 00:00:00

abstract：BACKGROUND:4CMenB (Bexsero), a vaccine developed against invasive meningococcal disease caused by capsular group B strains (MenB), was recently licensed for use by the European Medicines Agency. Assessment of 4CMenB strain coverage in specific epidemiologic settings is of primary importance to predict vaccination impac...

journal_title：Vaccine

authors： Frosi G,Biolchi A,Lo Sapio M,Rigat F,Gilchrist S,Lucidarme J,Findlow J,Borrow R,Pizza M,Giuliani MM,Medini D

更新日期：2013-10-09 00:00:00

abstract：:The potential outcomes of a Phase II schistosomiasis vaccine trial are explored using mathematical models which assume some natural immunity and a vaccine providing partial protection for a limited time. Analyses suggest that vaccination may have only a limited impact on life-long cumulative worm burdens and may lead ...

journal_title：Vaccine

authors： Woolhouse ME

更新日期：1995-08-01 00:00:00

abstract：:Immunologically based fertility control vaccines against zona pellucida (ZP) proteins are being developed in New Zealand for biocontrol of the brushtail possum (Trichosurus vulpecula), an introduced Australian marsupial pest. We have shown that immunization of female possums with recombinant possum ZP3 protein (rZP3) ...

journal_title：Vaccine

authors： Cui X,Duckworth JA,Molinia FC,Cowan PE

更新日期：2010-02-10 00:00:00

abstract：:Livestock production is a fundamental source of revenue and nutrition, wherein cattle-farming constitutes one of the major agricultural industries. Vectors and vector-borne diseases constitute one of the major factors that decrease the livelihood of all farming communities, more so in resource-poor communities and dev...

journal_title：Vaccine

authors： Robbertse L,Richards SA,Stutzer C,Olivier NA,Leisewitz AL,Crafford JE,Maritz-Olivier C

更新日期：2020-10-14 00:00:00

abstract：:Two double-blind randomised controlled studies (phase I and I/II) were performed to assess for the first time the safety and immunogenicity of a recombinant subunit gp350 Epstein-Barr virus (EBV) vaccine in 148 healthy adult volunteers. All candidate vaccine formulations had a good safety profile and were well tolerat...

journal_title：Vaccine

authors： Moutschen M,Léonard P,Sokal EM,Smets F,Haumont M,Mazzu P,Bollen A,Denamur F,Peeters P,Dubin G,Denis M

更新日期：2007-06-11 00:00:00

abstract：:The principle of deliberately infecting humans with infectious agents in a controlled setting, so-called controlled human infections (CHI), is not novel. Many CHI models have a long history and were established decades ago such as the intentional exposure to yellow fever and dengue performed in the 1900's (Reed, 1902)...

journal_title：Vaccine

authors： Roestenberg M,Mo A,Kremsner PG,Yazdanbakhsh M

更新日期：2017-12-18 00:00:00

abstract：:Porcine epidemic diarrhea (PED) is an important re-emergent infectious disease and inflicts huge economic losses to the swine industry worldwide. To meet the pressing need of developing a safe and cost-efficient PED maternal vaccine, we generated three PED subunit vaccine candidates, using recombined Salmonella flagel...

journal_title：Vaccine

authors： Li Q,Peng O,Wu T,Xu Z,Huang L,Zhang Y,Xue C,Wen Z,Zhou Q,Cao Y

更新日期：2018-03-07 00:00:00