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Strengthening of causality assessment of adverse events following immunization in the WHO South East Asia and Western Pacific regions: Lessons from the 2014 SEAR inter-country workshop.

Abstract：

BACKGROUND:Poorly managed AEFI undermine immunization programs. Improved surveillance in SEAR countries means more AEFIs but management varies. SEAR brought countries together to share AEFI experiences, and learn more about causality assessment. METHODS:Three day 10 country workshop (9 SEAR; 1 WPR). Participants outlined county AEFI experiences, undertook causality assessment for 8 AEFIs using WHO methodology, critiqued the process by questionnaire and had a discussion. RESULTS:All 10 valued AEFI monitoring and causality assessment, and praised the opportunity to share experiences. Participants determined a range of AEFI and causality assessment needs in SEAR such as adapting WHO Algorithm, CIOMS/Brighton definitions, WHO verbal autopsy to fit context, requesting a practical guide--AEFI definition, time interval, rates of AEFI for different vaccines and evidence for vaccine related causes of death under 24h. CONCLUSIONS:LMIC need WHO AEFI tools adapted to better fit LMIC. Learning from each other builds capacity. Sharing AEFI experiences, case reviews help LMIC improve practices.

journal_name

Vaccine

journal_title

Vaccine

authors

MacDonald NE,Guichard S,Amarasinghe A,Balakrishnan MR,2014 Inter-country SEAR Workshop Participants.

doi

10.1016/j.vaccine.2015.01.033

subject

Has Abstract

pub_date

2015-11-27 00:00:00

pages

6902-7

issue

48

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(15)00052-3

journal_volume

33

pub_type

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