Immunization of human hepatitis E viruses conferred protection against challenge by a camel hepatitis E virus.

abstract：:Bacterially-displayed peptide libraries have been widely used as an alternative to phage-displayed peptide libraries in screening epitopes or mimotopes of antibodies. Using a protective monoclonal antibody (mAb) 3B9 against hepatitis B virus (HBV) preS protein as target, mimotopes were successfully screened from a Fli...

journal_title：Vaccine

authors： Xin ZT,Liu C,Gao YP,Mao CQ,Zhao A,Zhang J,Shao NS,Ling SG,Xue YN

更新日期：2003-10-01 00:00:00

abstract：:A vaccine based upon a recombinant plant virus (CPMV-PARVO1), displaying a peptide derived from the VP2 capsid protein of canine parvovirus (CPV), has previously been described. To date, studies with the vaccine have utilized viable plant chimaeric particles (CVPs). In this study, CPMV-PARVO1 was inactivated by UV tre...

journal_title：Vaccine

authors： Langeveld JP,Brennan FR,Martínez-Torrecuadrada JL,Jones TD,Boshuizen RS,Vela C,Casal JI,Kamstrup S,Dalsgaard K,Meloen RH,Bendig MM,Hamilton WD

更新日期：2001-06-14 00:00:00

abstract：:Fifty injecting drug users (IDUs) were recruited to evaluate the efficacy of an hepatitis B virus (HBV) vaccination campaign to be carried out in a Public centre for Drug Users (PCDU). The vaccination schedule was successfully performed in most patients, who showed a great interest in this problem. After three doses o...

journal_title：Vaccine

authors： Lugoboni F,Migliozzi S,Schiesari F,Pauletto N,Bovo GL,Ciaffoni S,Mezzelani P

更新日期：1997-06-01 00:00:00

abstract：:All patients with congenital clotting disorders attending our centre routinely receive hepatitis B vaccination. We have assessed retrospectively the vaccine responses in 167 such individuals, with a follow-up period of up to 7.5 years. The initial postvaccine anti-HBs response was lower in older patients (p = 0.001), ...

journal_title：Vaccine

authors： Pillay D,Pereira C,Sabin C,Powell L,Zuckerman AJ,Lee CA

更新日期：1994-08-01 00:00:00

abstract：:Influenza B virus infections are mainly restricted to humans, which is partially caused by the inability of influenza B virus NS1 protein to counteract the innate immune response of other species. However, for cell culture-based influenza vaccine production non-human cells, such as Madin-Darby canine kidney (MDCK) cel...

journal_title：Vaccine

authors： Frensing T,Seitz C,Heynisch B,Patzina C,Kochs G,Reichl U

更新日期：2011-09-22 00:00:00

abstract：:The liver fluke Fasciola hepatica contributes to great economic and health losses in the cattle industry in many countries, including Poland. Unfortunately, no vaccine against fasciolosis is commercially available. We have designed a DNA vaccine and tested it in rats. Groups of male or female rats received one intramu...

journal_title：Vaccine

authors： Kofta W,Mieszczanek J,Płucienniczak G,Wedrychowicz H

更新日期：2000-07-01 00:00:00

abstract：:The use of viral vectors in heterologous prime-boost regimens to induce potent T cell responses in addition to humoral immunity is a promising vaccination strategy in the fight against malaria. We conducted an open-label, first-in-human, controlled Phase I study evaluating the safety and immunogenicity of Matrix-M adj...

journal_title：Vaccine

authors： Venkatraman N,Anagnostou N,Bliss C,Bowyer G,Wright D,Lövgren-Bengtsson K,Roberts R,Poulton I,Lawrie A,Ewer K,V S Hill A

更新日期：2017-10-27 00:00:00

abstract：:Pasteurella multocida OmpA (PmOmpA) belongs to the major and multifunctional Escherichia coli OmpA family of proteins. We have previously reported that the protein is conserved, immunogenic and an adhesin that binds host cells and host cell extracellular matrix molecules [Dabo SM, Confer AW, Quijano-Blas RA. Molecular...

journal_title：Vaccine

authors： Dabo SM,Confer A,Montelongo M,York P,Wyckoff JH 3rd

更新日期：2008-08-12 00:00:00

abstract：:In a phase III, double blind, randomized, noninferiority, multi-centre clinical trial, 817 infants were included and randomly assigned to vaccination with DTaP-IPV(Vero) (N=410) or DTaP-IPV(Mkc) (N=407) vaccines (Statens Serum Institut (SSI), Denmark) in the right thigh. All infants were vaccinated with Act-HIB (Sanof...

journal_title：Vaccine

authors： Pietrzyk JJ,Wysocki J,Pejcz J,Galaj A,Majda-Stanislawska E,Käyhty H,Thierry-Carstensen B,Jensen AM

更新日期：2008-09-26 00:00:00

abstract：PURPOSE:Human Papillomavirus (HPV) vaccine uptake remains low. Although publicly funded programs provide free or low cost vaccines to low-income children, barriers aside from cost may prevent disadvantaged girls from getting vaccinated. Prior studies have shown distance to health care as a potential barrier to utilizin...

journal_title：Vaccine

authors： Tsui J,Singhal R,Rodriguez HP,Gee GC,Glenn BA,Bastani R

更新日期：2013-04-12 00:00:00

abstract：:Mucin1 (MUC1) is expressed ubiquitously on breast cancer cells and is a potential target for the generation of cytotoxic T cells for vaccination against breast cancer. Thus far studies of the immunogenicity of MUC1 have used peptides from the variable number of tandem repeat (VNTR); mice so immunised can generate stro...

journal_title：Vaccine

authors： Pietersz GA,Li W,Osinski C,Apostolopoulos V,McKenzie IF

更新日期：2000-04-03 00:00:00

abstract：:A method was developed for cultivation of the strain Shigella flexneri 2a 77 with two attenuated markers. It ensures the preservation of the initial properties of the strain. The regimen for control of dissolved oxygen level was optimized. It was established that yeast extract is a necessary component of the nutritive...

journal_title：Vaccine

authors： Nenkov P,Bratoeva M,Vitanov T,Marinova S,Denchev V,Linde K

更新日期：1987-09-01 00:00:00

abstract：:Mycoplasma hyopneumoniae, the primary pathogen of enzootic pneumonia, occurs worldwide and causes major economic losses to the pig industry. M. hyopneumoniae infects pigs at mucosal surfaces of respiratory tract. The aim of the present study was to investigate if the protection rate against M. hyopneumoniae infection ...

journal_title：Vaccine

authors： Li Y,Li P,Wang X,Yu Q,Yang Q

更新日期：2012-03-09 00:00:00

abstract：OBJECTIVE:We related seroprevalence and outbreaks data in order to identify factors that could explain the occurrence of outbreaks despite high vaccination coverage in Medellín Colombia. METHODS:Samples from a population seroprevalence data obtained in 2009 in a random survey were analyzed. IgG levels were determined ...

journal_title：Vaccine

authors： Santacruz-Sanmartín E,Hincapié-Palacio D,Ospina MC,Perez-Toro O,Bernal-Restrepo LM,Buitrago-Giraldo S,Lenis-Ballesteros V,Díaz FJ

更新日期：2015-10-13 00:00:00

abstract：:Intranasal (i.n.) vaccination of mice with three doses of 40 microg of rRV stimulated low anti-ricin ELISA and neutralizing antibody responses, which were only marginally protective against aerosol-delivered 5-10 LD(50) of ricin toxin. To enhance the protection, and to reduce the lung injury of vaccinated mice that su...

journal_title：Vaccine

authors： Kende M,Tan X,Wlazlowski C,Williams R,Lindsey C,Del Giudice G

更新日期：2007-04-20 00:00:00

abstract：INTRODUCTION:During the 2018-2019 influenza season, vaccination coverage among U.S. children was 62.6%. The purpose of this study was to estimate the prevalence of influenza vaccinations among pediatric patients seen in U.S. health centers, and to explore potential disparities in vaccination coverage among subpopulatio...

journal_title：Vaccine

authors： Lebrun-Harris LA,Mendel Van Alstyne JA,Sripipatana A

更新日期：2020-09-03 00:00:00

abstract：:The purpose of the present study was to compare serum and mucosal immune responses following either aerosol (Aer) or subcutaneous (SQ) measles immunization of Mexican school children. A cohort of 49 children from 6 to 7 years of age received either Aer ( n = 22) or SQ ( n = 27) Edmonston-Zagreb (EZ) measles vaccine. S...

journal_title：Vaccine

authors： Bellanti JA,Zeligs BJ,Mendez-Inocencio J,García-Garcia ML,Islas-Romero R,Omidvar B,Omidvar J,Kim G,Fernandez De Castro J,Sepulveda Amor J,Walls L,Bellini WJ,Valdespino-Gomez JL

更新日期：2004-03-12 00:00:00

abstract：:It is well documented that adjuvants improve the immune response generated by traditional viral vaccines, but less is known about the effects of adjuvants on the immune response elicited by DNA vaccines. In this study, we have investigated the use of RN-205 (immunomodulator containing a membrane rich in lipopolysaccha...

journal_title：Vaccine

authors： Zamorano P,Taboga O,Domínguez M,Romera A,Puntel M,Tami C,Mongini C,Waldner C,Palma E,Sadir A

更新日期：2002-06-21 00:00:00

abstract：BACKGROUND:Non-typhoid Salmonella (NTS) is a leading cause of food-borne illness with more than 90 million annual cases and an emerging antimicrobial resistance among the strains worldwide. Paradoxically, no vaccines are available against these pathogens. Numerous NTS strains share surface O-antigens with Salmonella en...

journal_title：Vaccine

authors： Kantele A,Pakkanen SH,Siitonen A,Karttunen R,Kantele JM

更新日期：2012-11-26 00:00:00

abstract：PURPOSE:Meningococcal C conjugate vaccine was included in December 2000 in the Spanish childhood vaccination at 2, 4 and 6 months of age. In 2006, routine vaccination was modified to two doses at 2 and 4-6 months and a booster dose during the second year of age. Additionally, successive catch-up campaigns were launched...

journal_title：Vaccine

authors： Garrido-Estepa M,León-Gómez I,Herruzo R,Cano R

更新日期：2014-05-07 00:00:00

abstract：:Vaccines reside in a complex multiscale system that includes biological, clinical, behavioral, social, operational, environmental, and economical relationships. Not accounting for these systems when making decisions about vaccines can result in changes that have little effect rather than solutions, lead to unsustainab...

journal_title：Vaccine

authors： Lee BY,Mueller LE,Tilchin CG

更新日期：2017-01-20 00:00:00

abstract：:Envelope glycoprotein E2 is the most immunogenic protein of classical swine fever virus (CSFV). In a proposed model of the antigenic structure of E2, the N-terminal half of E2 forms two independent structural antigenic units, A and BC. E2 without transmembrane region (E2-TMR) is expressed and secreted into the medium ...

journal_title：Vaccine

authors： van Rijn PA,van Gennip HG,Moormann RJ

更新日期：1999-02-05 00:00:00

abstract：:Varied doses of Taishan Pinus massoniana pollen polysaccharide (TPPPS) and Astragalus polysaccharide (APS) extracted by hot water extraction and ethanol precipitation method were added to the vaccine in order to prepare polysaccharide-rabbit haemorrhagic disease (RHD) tissue inactivated vaccine. The purpose was to stu...

journal_title：Vaccine

authors： Wei K,Sun Z,Yan Z,Tan Y,Wang H,Zhu X,Wang X,Sheng P,Zhu R

更新日期：2011-03-21 00:00:00

abstract：OBJECTIVE:Evaluating HIV-1 specific T-cell response in African populations is sometimes compromised by extensive virus diversity and paucity of non-clade B reagents. We evaluated whether consensus group M (ConM) peptides could serve as comparable substitutes for detecting immune responses in clade A and clade D HIV-1 i...

journal_title：Vaccine

authors： Mugaba S,Nakiboneka R,Nanyonjo M,Bugembe-Lule D,Kaddu I,Nanteza B,Tweyongyere R,Kaleebu P,Serwanga J

更新日期：2014-06-24 00:00:00

abstract：:We have previously described the generation of HIV-1 V3-specific cytotoxic T-lymphocytes (CTL) responses in BALB/c (H-2d) mice following immunization with Ty-virus-like particles carrying the V3 loop of gp120 (V3-VLPs) without adjuvant. In this study the effects of various adjuvants on CTL induction by V3-VLPs was exa...

journal_title：Vaccine

authors： Harris SJ,Woodrow SA,Gearing AJ,Adams SE,Kingsman AJ,Layton GT

更新日期：1996-07-01 00:00:00

abstract：:The physico-chemical characterization of NadADelta(351-405), a recombinant protein discovered by reverse vaccinology, component of a candidate vaccine against Neisseria meningitidis serotype B is presented. Analytical methods like mass spectrometry, electrophoresis, optical spectroscopy and SEC-MALLS have been applied...

journal_title：Vaccine

authors： Magagnoli C,Bardotti A,De Conciliis G,Galasso R,Tomei M,Campa C,Pennatini C,Cerchioni M,Fabbri B,Giannini S,Mattioli GL,Biolchi A,D'Ascenzi S,Helling F

更新日期：2009-03-26 00:00:00

abstract：:After 16 years of no vaccination against pertussis in Sweden, mass vaccination of infants and catch-up vaccination of children up to 10 years with a monocomponent pertussis toxoid vaccine was performed in the Greater Gothenburg area of Sweden between 1995 and 1999. At the end of the project in February 1999, 56% of al...

journal_title：Vaccine

authors： Trollfors B,Dotevall L,Sundh V,Welinder-Olsson C

更新日期：2011-03-16 00:00:00

abstract：:Hepatitis B virus (HBV) infection and HBV-associated diseases are prevalent in many parts of the Middle East and North Africa. Postnatal horizontal childhood transmission appears to be the predominant method by which high hepatitis B carrier rates are maintained. To control hepatitis B in this region, mass immunizatio...

journal_title：Vaccine

authors： Toukan A

更新日期：1990-03-01 00:00:00

abstract：:Immunization with xenogeneic DNA is a promising cancer treatment to overcome tolerance to self-antigens. Heat shock protein 70 (HSP70) is over-expressed in various kinds of tumors and is believed to be involved in tumor progression. This study tested a xenogeneic chicken HSP70 (chHSP70) DNA vaccine in an experimental ...

journal_title：Vaccine

authors： Yu WY,Chuang TF,Guichard C,El-Garch H,Tierny D,Laio AT,Lin CS,Chiou KH,Tsai CL,Liu CH,Li WC,Fischer L,Chu RM

更新日期：2011-04-18 00:00:00

abstract：:Human papillomavirus (HPV) infection is highly prevalent and can lead to cancer; the development of safe and efficacious vaccines for HPV is a major public health concern. The two licensed HPV vaccines contain recombinant virus-like particles of HPV 16 and 18; one of such vaccines also protects against HPV types 6 and...

journal_title：Vaccine

authors： Giacomet V,Penagini F,Trabattoni D,Viganò A,Rainone V,Bernazzani G,Bonardi CM,Clerici M,Bedogni G,Zuccotti GV

更新日期：2014-09-29 00:00:00