In vitro analysis of the minimal inhibitory concentration values of different generations of anti-methicillin-resistant Staphylococcus aureus antibiotics.

Abstract:

:Methicillin-resistant Staphylococcus aureus (MRSA) resistance to antimicrobials may result in the increased risk of treatment failure. The objective of the study was to analyse in vitro MRSA susceptibility to vancomycin, linezolid, daptomycin, tigecycline, ceftaroline, dalbavancin, clindamycin, ciprofloxacin and trimethoprim/sulfamethoxazole. All MRSA strains isolated from hospitalised patients were analysed according to the current microbiological recommendations. Finally, a total of 124 MRSA strains were analysed; all were susceptible to tested antibiotics. Dalbavancin had the lowest minimum inhibitory concentration (MIC), and vancomycin the highest MIC value. There were 28/124 strains of MRSA susceptible for clindamycin, 36/124 for ciprofloxacin and 121/124 for trimethoprim/sulfamethoxazole. Dalbavancin was the most effective antimicrobial in our study.

journal_name

Indian J Med Microbiol

authors

Guzek A,Rybicki Z,Tomaszewski D

doi

10.4103/ijmm.IJMM_17_136

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

119-120

issue

1

eissn

0255-0857

issn

1998-3646

pii

IndianJMedMicrobiol_2018_36_1_119_231659

journal_volume

36

pub_type

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