Abstract:
PURPOSE:To determine the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) for the extracts of the leaves and seeds of the plant Azadirachta indica against various dermatophytes. METHODS:Clinical isolates of dermatophytes(Trichophyton rubrum, Trichophyton mentagrophytes and Microsporum nanum) were treated with extracts of leaves and seeds of the plant Azadirachta indica (neem) for antifungal activity by in vitro tube dilution technique. RESULTS:The MIC of neem seed extracts was 31 microg/mL for all the dermatophytes tested. The neem seed extract at 15 microg/mL concentration (below MIC) was observed to be sufficient for distorting the growth pattern of the organisms tested. CONCLUSIONS:The changes in growth curve of the treated dermatophytes were found to be statistically significant with reference to the untreated fungi.
journal_name
Indian J Med Microbioljournal_title
Indian journal of medical microbiologyauthors
Natarajan V,Venugopal PV,Menon Tsubject
Has Abstractpub_date
2003-04-01 00:00:00pages
98-101issue
2eissn
0255-0857issn
1998-3646journal_volume
21pub_type
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
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