Demographic profile of healthy children with nasopharyngeal colonisation of Streptococcus pneumoniae: A research paper.

Abstract:

BACKGROUND:Pneumonia is a preventable cause of mortality in children. Streptococcus pneumoniae colonising the nasopharynx of healthy children can cause invasive diseases and the serotype distribution of colonisation isolates should be an indicator of invasive disease, antibiotic resistance profiles, and potential vaccine coverage. Identifying factors influencing nasopharyngeal colonisation, the serotypes and antimicrobial resistance pattern can improve rational preventive strategies. OBJECTIVES:Identify risk factors associated with nasopharyngeal colonisation of S.pneumoniae in healthy children between 6 months to 5 years of age. Determine the serotype and antibiotic sensitivity of S. pneumoniae isolated from nasopharynx of healthy children. METHODS:This prospective observational included 500 healthy children, 6months to 5 years of age. Demographic features of the study population, the serotypes and antimicrobial sensitivity pattern of S.Pneumoniae isolated from cultures of nasopharyngeal swabs were subjected to statistical analysis. RESULTS:S. pneumoniae was isolated in 9% of 450 children. Increased nasopharyngeal carriage rate was associated with overcrowding 48.8% and poor ventilation 35.5%. 6B (n=16) was the most common serotype isolated. 69% were serogroups known to cause invasive disease All S. pneumoniae isolates were susceptible to vancomycin and linezolid. Antimicrobial susceptibility of PCV 7 serotypes were greater than non PCV 7 serotypes for almost all antimicrobials tested. Penicillin resistance was 11 % and MDR 51.

journal_name

Indian J Med Microbiol

authors

Raman R,Sankar J,Putlibai S,Raghavan V

doi

10.4103/ijmm.IJMM_15_347

subject

Has Abstract

pub_date

2017-10-01 00:00:00

pages

607-609

issue

4

eissn

0255-0857

issn

1998-3646

pii

IndianJMedMicrobiol_2017_35_4_607_224411

journal_volume

35

pub_type

杂志文章
  • Treatment of discarded blood units: disinfection with hypochlorite / formalin versus steam sterilization.

    abstract::Blood bank regulations and bio medical waste rules of India advocate disinfection of contaminated blood units. Incineration is not recommended due to poly-vinyl chloride (PVC) content of blood bags. This study was designed to evaluate the efficacy of chemical disinfection of blood units deliberately contaminated with ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Chitnis V,Chitnis S,Patil S,Chitnis D

    更新日期:2003-10-01 00:00:00

  • Asymptomatic bacteriuria in school going children.

    abstract:PURPOSE:The present study was undertaken to determine the prevalence of asymptomatic bacteriuria in school going children of different age groups and sex and to isolate the organisms responsible for asymptomatic bacteriuria and to know their antimicrobial susceptibility pattern. METHODS:A total of 1817 school children...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Kumar CS,Jairam A,Chetan S,Sudesh P,Kapur I,Srikaramallya.

    更新日期:2002-01-01 00:00:00

  • Vibrionaceae from cases of acute diarrhoea and their antimicrobial sensitivity pattern - a five year prospective study.

    abstract::Over a five year period, stool samples were screened for Vibrionaceae from cases of acute diarrhoea, to study their isolation rate and their antimicrobial sensitivity pattern. All the isolates were identified by standard laboratory techniques. A total of 323 species belonging to Vibrionaceae were isolated from 4492 st...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Mathur M,De A,Saraswathi K,Varaiya A,Athalye S

    更新日期:2003-07-01 00:00:00

  • Application of real-time quantitative polymerase chain reaction assay to detect Legionella pneumophila in patients of community-acquired pneumonia in a tertiary care hospital.

    abstract::Legionella pneumophila is one of the important pathogen responsible for community -acquired pneumonia attributing for 1-5% of cases. Since early and accurate therapy reduces mortality, rapid and reliable diagnostic methods are needed. A total of 134 samples of blood, urine and respiratory tract fluids were collected. ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.195353

    authors: Angrup A,Chaudhry R,Sharma S,Valavane A,Passi K,Padmaja K,Javed S,Dey AB,Dhawan B,Kabra SK

    更新日期:2016-10-01 00:00:00

  • Extended spectrum beta lactamase (ESBL) mediated resistance to third generation cephalosporins among Klebsiella pneumoniae in Chennai.

    abstract:PURPOSE:To examine the incidence of extended spectrum b lactamase (ESbL) producing strains and multidrug resistant strains of Klebsiella pneumoniae isolated from children between 0-5 years of age. METHODS:Multidrug resistance and ESbL production was studied in a total of 120 isolates of Klebsiella pneumoniae obtained ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Subha A,Ananthan S

    更新日期:2002-04-01 00:00:00

  • Recent advances in rhinosporidiosis and Rhinosporidium seeberi.

    abstract::Rhinosporidiosis and its causative pathogen Rhinosporidium seeberi have been known for over a hundred years. Yet unresolved enigmas in rhinosporidiosis include the mode of infection, mechanisms of spread, mechanisms of immunity, some aspects of histopathology e.g. the significance of transepidermal elimination of spor...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Arseculeratne SN

    更新日期:2002-07-01 00:00:00

  • Colistin susceptibility testing of gram-negative bacilli: Better performance of vitek2 system than E-test compared to broth microdilution method as the gold standard test.

    abstract:Introduction:Unavailability of optimal susceptibility testing (ST) challenges the clinical use of colistin. Broth microdilution (BMD), which is the reference for colistin ST, is inconvenient for diagnostics. Vitek2 and E-test although technically easier, are no longer recommended. Materials and Methods:For the evaluat...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_19_480

    authors: Das S,Roy S,Roy S,Goelv G,Sinha S,Mathur P,Walia K,Bhattacharya S

    更新日期:2020-01-01 00:00:00

  • One year trends in the gram-negative bacterial antibiotic susceptibility patterns in a medical intensive care unit in South India.

    abstract:PURPOSE:To describe the changes in antibiotic susceptibility patterns of common intensive care unit pathogens with time from the medical intensive care unit of a tertiary care hospital. METHODS:A prospective observational study was conducted in the medical intensive care unit (MICU) of a 2100 bed tertiary care hospita...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.34764

    authors: Kaul S,Brahmadathan KN,Jagannati M,Sudarsanam TD,Pitchamuthu K,Abraham OC,John G

    更新日期:2007-07-01 00:00:00

  • Evaluation of biphasic culture system for mycobacterial isolation from the sputum of patients with pulmonary tuberculosis.

    abstract::Mycobacterial diseases continue to cause high morbidity and mortality. Isolation, identification and sensitivity testing form the backbone of laboratory investigations. M. tuberculosis isolation needs 6-8 weeks on conventional egg containing media. For rapid isolation various methods have been evaluated. We evaluated ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.16050

    authors: Ghatole M,Sable C,Kamale P,Kandle S,Jahagirdar V,Yemul V

    更新日期:2005-04-01 00:00:00

  • Human leucocyte antigen Class I and II alleles associated with anti-hepatitis C virus-positive patients of North India.

    abstract:PURPOSE:Humans are the only known natural hosts of hepatitis C virus (HCV). This study was undertaken to examine the frequencies of human leucocyte antigens (HLAs) Class I and Class II genotype profiles in anti-HCV-infected patients of Northern India. MATERIALS AND METHODS:From a period of January 2013 to August 2014,...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.188317

    authors: Chowdhry M,Makroo RN,Singh M,Agrawal S,Kumar M,Thakur Y

    更新日期:2016-07-01 00:00:00

  • Erratum: Endemic Indian clones of Klebsiella pneumoniae harbouring New Delhi metallo beta lactamase 1 on a hybrid plasmid replicon type: A case of changing New Delhi metallo beta lactamase plasmid landscapes in India?

    abstract::[This corrects the article DOI: 10.4103/0255-0857.188314.]. ...

    journal_title:Indian journal of medical microbiology

    pub_type: 已发布勘误

    doi:10.4103/0255-0857.195384

    authors:

    更新日期:2016-10-01 00:00:00

  • An ocular cysticercosis case: Caused by Asian genotype of Taenia solium.

    abstract::An ocular cysticercosis case of a 42-year-old male, who presented with anterior uveitis is being reported. Microscopical examination of the cyst revealed presence of only one hooklet suggestive of T. solium cysticercus. Mitochondrial DNA analysis confirmed it to be T. solium cysticercus of Asian genotype. This is the ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.167319

    authors: Sharma M,Beke N,Khurana S,Bhatti HS,Sehgal R,Malla N

    更新日期:2015-10-01 00:00:00

  • Review of a 7-year record of the bacteriological profile of airway secretions of children with cystic fibrosis in North India.

    abstract:Background:Cystic fibrosis (CF) is now a recognised entity in India, with prevalence rates between 1/10,000 and 1/50,000. However, no data were available with regard to the profile of respiratory pathogens in the Indian setting. Materials and Methods:The records of respiratory secretion bacterial cultures of children ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_18_424

    authors: Gautam V,Kaza P,Mathew JL,Kaur V,Sharma M,Ray P

    更新日期:2019-04-01 00:00:00

  • Spoligotype patterns of Mycobacterium tuberculosis isolated from extra pulmonary tuberculosis patients in Puducherry, India.

    abstract:PURPOSE:Genotyping studies like spoligotyping are valuable tools in understanding the genetic diversity and epidemiology of Mycobacterium tuberculosis. Though there are reports of spoligotyping of M. tuberculosis isolates from pulmonary specimens from different parts of India, spoligotyping of extra pulmonary tuberculo...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.154871

    authors: Kandhakumari G,Stephen S,Sivakumar S,Narayanan S

    更新日期:2015-04-01 00:00:00

  • Dynamics of the occurrence of influenza in relation to seasonal variation in Chennai, Tamil Nadu: A 7 -year cumulative study.

    abstract:Background:Influenza viruses have emerged as virulent pathogens causing considerable burden across the world. A thorough understanding of the pattern in occurrence of influenza globally is the need of hour. The present study deals with analysis of the dynamics of Influenza virus, especially the influence of seasonal ch...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_19_226

    authors: Kiruba R,Suresh Babu BV,Sheriff AK,Gunasekaran P,Anupama CP,Saran N,Kumar VS,Padmapriya P,Chakravarthy NN,Kaveri K

    更新日期:2019-07-01 00:00:00

  • T-cell recognition of iron-regulated culture filtrate proteins of Mycobacterium tuberculosis in tuberculosis patients and endemic normal controls.

    abstract:BACKGROUND:Culture filtrate proteins (CFPs) of Mycobacterium tuberculosis are potential vaccine candidates. OBJECTIVE:The aim was to study the influence of iron levels on CFPs and assess the immuno-protective potential of defined antigenic fractions from high (8 μg Fe/mL) and low iron (0.02 μg Fe / mL) cultures of M. ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.99495

    authors: Duggirala S,Venu K,Subhakar K,Sritharan M

    更新日期:2012-07-01 00:00:00

  • Cutaneous cryptococcosis among HIV infected patients.

    abstract::Five patients with HIV associated cutaneous cryptococcal infection are reported. ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Vasanthi S,Padmavathy BK,Gopal R,Sundaram RS,Manoharan G

    更新日期:2002-07-01 00:00:00

  • The non-association of Panton-Valentine leukocidin and mecA genes in the genome of Staphylococcus aureus from hospitals in South Western Nigeria.

    abstract:PURPOSE:Virulence genes play important roles in pathogenesis of infections caused by S. aureus. The aim of this study was to determine the prevalence of PVL, eta and mecA genes in S. aureus isolated from patients in South-Western Nigeria. MATERIALS AND METHODS:In this study, a total of 116 S. aureus isolates from the ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.96675

    authors: Terry Alli OA,Ogbolu DO,Mustapha JO,Akinbami R,Ajayi AO

    更新日期:2012-04-01 00:00:00

  • The use of E-test for the drug susceptibility testing of Mycobacterium tuberculosis - a solution or an illusion?

    abstract:AIM:To evaluate E-test as a tool for rapid determination of drug susceptibility against the conventional LJ method focusing on reliability, expense, ease of standardization and performance of the technique in low resource settings. MATERIALS AND METHODS:A total of 74 clinical isolates (2004-2005) of Mycobacterium tube...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.58725

    authors: Verma JS,Rawat D,Hasan A,Capoor MR,Gupta K,Deb M,Aggarwal P,Nair D

    更新日期:2010-01-01 00:00:00

  • Catheter-related Brevibacterium casei bloodstream infection in a child with aplastic anaemia.

    abstract::Brevibacteria are a part of the normal skin flora and may be dismissed in blood cultures as contaminants. They have been reported as opportunistic pathogens in immunocompromised patients. We report a catheter-related bloodstream infection with Brevibacterium casei in a 6-year-old child with aplastic anaemia. Treatment...

    journal_title:Indian journal of medical microbiology

    pub_type:

    doi:10.4103/ijmm.IJMM_20_292

    authors: Joshi S,Misra R,Kirolikar S,Mushrif S

    更新日期:2020-04-01 00:00:00

  • Evaluation of a modified double-disc synergy test for detection of extended spectrum beta-lactamases in AMPC beta-lactamase-producing proteus mirabilis.

    abstract::The detection of extended-spectrum beta-lactamases (ESBLs) in gram-negative bacteria that produce AmpC beta-lactamases is problematic. In the present study, the performance of modified double-disc synergy test (MDDST) that employs a combination of cefepime and piperacillin-tazobactam for the detection of Proteus mirab...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.38860

    authors: Khan MK,Thukral SS,Gaind R

    更新日期:2008-01-01 00:00:00

  • Acute necrotizing pancreatitis with pancreatic abscess due to Prevotella species in a diabetic.

    abstract::Acute pancreatitis occasionally presents as pancreatic abscess with complications like pleural effusion and ascites. There are several pre-disposing factors, the most common being cholelithiaisis, alcohol abuse, infective causes, trauma, and metabolic causes such as diabetic ketoacidosis, while some cases are idiopath...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.58735

    authors: Sonavane A,Baradkar V,Salunkhe P,D'Souza D,Kumar S

    更新日期:2010-01-01 00:00:00

  • Lepromatous leprosy of histoid type.

    abstract::Histoid leprosy is a variant of lepromatous leprosy, which develops as a result of resistance to dapsone monotherapy. Here we report two cases of lepromatous leprosy of histoid type, one with typical and another with atypical presentations. ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.31069

    authors: Annigeri SR,Metgud SC,Patil JR

    更新日期:2007-01-01 00:00:00

  • Rising trend of antimicrobial resistance among Neisseria gonorrhoeae isolates and the emergence of N. gonorrhoeae isolate with decreased susceptibility to ceftriaxone.

    abstract:CONTEXT:Gonorrhoea is one of the most common sexually transmitted infections (STI) in developing countries and is a global health problem. AIMS:To analyze the trend of antimicrobial susceptibility of Neisseria gonorrhoeae isolates over the years, in a tertiary care hospital of North India. SETTINGS AND DESIGN:The stu...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.148374

    authors: Bharara T,Bhalla P,Rawat D,Garg VK,Sardana K,Chakravarti A

    更新日期:2015-01-01 00:00:00

  • Cutaneous leishmaniasis: an emerging infection in a non-endemic area and a brief update.

    abstract::We report here the emergence of a new focus of cutaneous leishmaniasis (CL) due to Leishmania tropica (L. tropica) in the Ajmer city of Rajasthan, India, a previously non-endemic area. Between January-February 2006, 13 new indigenously acquired cases of CL were diagnosed among the patients attending the Skin and STD d...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.34774

    authors: Rastogi V,Nirwan PS

    更新日期:2007-07-01 00:00:00

  • Antibiotic resistance in ocular bacterial pathogens.

    abstract::Bacterial infections of the eye are common and ophthalmologists are spoilt for choice with a variety of antibiotics available in the market. Antibiotics can be administered in the eye by a number of routes; topical, subconjunctival, subtenon and intraocular. Apart from a gamut of eye drops available, ophthalmologists ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章,评审

    doi:10.4103/0255-0857.83903

    authors: Sharma S

    更新日期:2011-07-01 00:00:00

  • Identification of Raoultella spp.: Comparison of three methods.

    abstract:Background:Raoultella is a Gram-negative bacteria, which commonly occur in the natural environment such as water, soil and on plants. In recent years, Raoultella spp. gained more interest. There is also an increasing number of publications describing mainly clinical cases involving these bacteria. Identification of Rao...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_17_99

    authors: Sekowska A,Mikucka A,Gospodarek-Komkowska E

    更新日期:2018-04-01 00:00:00

  • Comparison of various microbiological tests including polymerase chain reaction for the diagnosis of osteoarticular tuberculosis.

    abstract:PURPOSE:To evaluate the utility of the polymerase chain reaction (PCR) test for diagnosing osteoarticular tuberculosis (TB). METHODS:Clinical samples (synovial tissue and synovial fluid) obtained from 23 cases of suspected osteoarticular tuberculosis were subjected to Ziehl Neelsen (ZN) smear examination, radiometric ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Negi SS,Gupta S,Khare S,Lal S

    更新日期:2005-10-01 00:00:00

  • The seroepidemiology of Rubella in Amritsar (Punjab).

    abstract::Seroprevalence of Rubella was determined in 580 women including 80 women of medical community of district Amritsar, by ELISA test. The overall Rubella IgG seropositivity was 68.8% while in women of medical community it was 80%. Maximum number of women were seropositive (77.2%) in age group 26-35 years. Significantly h...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Singla N,Jindal N,Aggarwal A

    更新日期:2004-01-01 00:00:00

  • Detection of mutation in isoniazid-resistant Mycobacterium tuberculosis isolates from tuberculosis patients in Belarus.

    abstract::The aim of this study was to investigate the frequency, location and type of katG mutations in Mycobacterium tuberculosis strains isolated from patients in Belarus. Forty two isoniazid-resistant isolates were identified from sputum of 163 patients with active pulmonary tuberculosis. Drug susceptibility testing was det...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.40528

    authors: Bostanabad SZ,Titov LP,Bahrmand A,Nojoumi SA

    更新日期:2008-04-01 00:00:00