Abstract:
PURPOSE:The objective of this study is to determine the role of quantitative cultures of non-bronchoscopic samples such as blinded bronchial sampling (BBS) and endotracheal aspirates (ETA) in the management of ventilator associated pneumonia (VAP). The study also evaluates the clinical diagnosis of VAP based on the inclusion of Gram stain results of BBS/ETA samples into modified clinical pulmonary infection score (CPIS). METHODS:Fifteen out of the 120 patients admitted to respiratory intensive care unit under mechanical ventilation for more than 48 hours with a clinical suspicion of VAP, were included in this study. Quantitative cultures of BBS and ETA were performed from all the 15 patients. RESULTS:VAP was confirmed in 11 out of 15 cases by quantitative cultures of either the BBS or ETA samples. The condition of 8/11 VAP confirmed patients improved significantly with the change in antibiotic therapy. The overall mortality rate was found to be 18%. The agreement between BBS and ETA results was found to be 83.3%. Modified-clinical pulmonary infection score (CPIS) increased significantly when Gram stain results of BBS/ETA samples were included, thereby strengthening the clinical diagnosis of VAP. CONCLUSIONS:Quantitative culture of lower respiratory tract samples obtained by non-bronchoscopic methods may be a useful alternative to bronchoscopy, in the diagnosis of VAP. Inclusion of Gram stain results of BBS/ETA into modified-CPIS may augment the diagnostic evaluation of VAP.
journal_name
Indian J Med Microbioljournal_title
Indian journal of medical microbiologyauthors
Rajasekhar T,Anuradha K,Suhasini T,Lakshmi Vdoi
10.4103/0255-0857.25226subject
Has Abstractpub_date
2006-04-01 00:00:00pages
107-13issue
2eissn
0255-0857issn
1998-3646journal_volume
24pub_type
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journal_title:Indian journal of medical microbiology
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doi:10.4103/0255-0857.124308
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journal_title:Indian journal of medical microbiology
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doi:10.4103/0255-0857.99506
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journal_title:Indian journal of medical microbiology
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doi:10.4103/0255-0857.25209
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journal_title:Indian journal of medical microbiology
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doi:
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journal_title:Indian journal of medical microbiology
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doi:10.4103/0255-0857.90173
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journal_title:Indian journal of medical microbiology
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doi:10.4103/0255-0857.32716
更新日期:2007-04-01 00:00:00
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journal_title:Indian journal of medical microbiology
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journal_title:Indian journal of medical microbiology
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.148400
更新日期:2015-01-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:
更新日期:2002-10-01 00:00:00
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journal_title:Indian journal of medical microbiology
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doi:
更新日期:2006-07-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.81801
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.55464
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:
更新日期:2003-07-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.62501
更新日期:2010-04-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.154889
更新日期:2015-04-01 00:00:00
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journal_title:Indian journal of medical microbiology
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doi:10.4103/0255-0857.31059
更新日期:2007-01-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.13871
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.71817
更新日期:2010-10-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
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更新日期:2010-07-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.150895
更新日期:2015-02-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/0255-0857.180282
更新日期:2016-04-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/ijmm.IJMM_18_65
更新日期:2018-04-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章,评审
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更新日期:2010-10-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章,评审
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更新日期:2009-04-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:10.4103/ijmm.IJMM_17_201
更新日期:2017-10-01 00:00:00
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journal_title:Indian journal of medical microbiology
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00