Drug resistance profile of human Mycobacterium avium complex strains from India.

Abstract:

PURPOSE:To determine minimum inhibitory concentration (MIC) of various anti-tuberculosis drugs for Mycobacterium avium complex (MAC) strains isolated from clinical samples. METHODS:Forty-nine human isolates of MAC were tested for susceptibility to nine chemotherapeutic agents. All isolates were from Indian patients suffering from chronic pulmonary mycobacteriosis. Drug susceptibility was performed both by agar dilution and MIC method. MIC values were analysed, both visually and by enzyme-linked immunosorbent assay reader. RESULTS:More than 40% of the MAC isolates were sensitive to ciprofloxacine (48.98%), amikacin (46.94%) and roxithromycin (42.86%) by the MIC method. In contrast, the isolates showed high degree of resistance to the first line antituberculosis drugs: only 28.6% were sensitive to rifampicine, 22.85% to isoniazid and ethambutol each and 36.7% were sensitive to streptomycin. In addition, 22.85% of the strains were sensitive to clofazimine and 34.7% to kanamycin. CONCLUSIONS:Results of the study confirm the suitability of the rapid broth micro dilution (MIC) method as a simple yet reliable method to assay for the drug susceptibility of nontuberculosis mycobacterium.

journal_name

Indian J Med Microbiol

authors

Venugopal D,Kumar S,Isa M,Bose M

doi

10.4103/0255-0857.32716

subject

Has Abstract

pub_date

2007-04-01 00:00:00

pages

115-20

issue

2

eissn

0255-0857

issn

1998-3646

journal_volume

25

pub_type

杂志文章
  • A rare case of tubercular cerebellar abscess.

    abstract::Tubercular brain abscess are uncommon and tubercular cerebellar abscess are rarely reported. Most of these cases occur in immunocompromised patients. We report a case of multiple cerebellar abscesses in a 55-year-old HIV seronegative non-diabetic female, who complained of headache, neck pain and unsteadiness of gait s...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.55464

    authors: Wanjari K,Baradkar VP,Nataraj G,Kumar S

    更新日期:2009-10-01 00:00:00

  • Lepromatous leprosy of histoid type.

    abstract::Histoid leprosy is a variant of lepromatous leprosy, which develops as a result of resistance to dapsone monotherapy. Here we report two cases of lepromatous leprosy of histoid type, one with typical and another with atypical presentations. ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.31069

    authors: Annigeri SR,Metgud SC,Patil JR

    更新日期:2007-01-01 00:00:00

  • Genotypes of hepatitis C virus in the Indian sub-continent: a decade-long experience from a tertiary care hospital in South India.

    abstract:BACKGROUND:Hepatitis C virus (HCV) is a leading cause of chronic liver disease (CLD) that can progress to cirrhosis and hepatocellular carcinoma. Genotypes of HCV can vary in pathogenicity and can impact on treatment outcome. OBJECTIVES:To study the different genotypes among patients with HCV related CLD attending a t...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.118875

    authors: Christdas J,Sivakumar J,David J,Daniel HD,Raghuraman S,Abraham P

    更新日期:2013-10-01 00:00:00

  • Prosthetic joint infection due to Lysobacter thermophilus diagnosed by 16S rRNA gene sequencing.

    abstract::We report the first case of prosthetic joint infection caused by Lysobacter thermophilus which was identified by 16S rRNA gene sequencing. Removal of prosthesis followed by antibiotic treatment resulted in good clinical outcome. This case illustrates the use of molecular diagnostics to detect uncommon organisms in sus...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.174124

    authors: Dhawan B,Sebastian S,Malhotra R,Kapil A,Gautam D

    更新日期:2016-01-01 00:00:00

  • Types of human papillomavirus observed in hospital-based population.

    abstract:Background and Objectives:Human papillomavirus (HPV) is the causative agent of cervical cancer, a major cause of cancer mortality in Indian women. The current study was undertaken to add information to the existing data on HPV type distribution in Indians, in an attempt to document HPV types for future vaccination prog...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_19_451

    authors: Wagh P,Kulkarni P,Kerkar S,Tongaonkar H,Deodhar K,Rekhi B,Salvi V,Chaudhari H,Warke H,Mania-Pramanik J

    更新日期:2019-10-01 00:00:00

  • Seroprevalence, risk factors and genotype distribution for Hepatitis C infection: A study from rural hospital in Maharashtra.

    abstract:BACKGROUND AND OBJECTIVES:Hepatitis C is global health problem affecting a significant portion of the world's population. Available data in Western Maharashtra on seroprevalence, risk factors and genotype distribution are very limited. OBJECTIVES:The present study was carried out to estimate the seroprevalence, factor...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_16_96

    authors: Patil SR,Datkhile KD,Ghorpade MV,Patil SS,Kakade SV

    更新日期:2017-10-01 00:00:00

  • The seroepidemiology of Rubella in Amritsar (Punjab).

    abstract::Seroprevalence of Rubella was determined in 580 women including 80 women of medical community of district Amritsar, by ELISA test. The overall Rubella IgG seropositivity was 68.8% while in women of medical community it was 80%. Maximum number of women were seropositive (77.2%) in age group 26-35 years. Significantly h...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Singla N,Jindal N,Aggarwal A

    更新日期:2004-01-01 00:00:00

  • High prevalence of hepatitis A virus antibody among Bangladeshi children and young adults warrants pre-immunization screening of antibody in HAV vaccination strategy.

    abstract::Serum samples from 465 subjects aged between 1 and 25 years were tested for antibody against hepatitis A virus (HAV) [anti-HAV IgG and IgM] to determine the seroprevalence of HAV antibody and do a cost-benefit analysis for decision making about vaccination against HAV among the general population of Bangladesh. A high...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Ahmed M,Munshi SU,Nessa A,Ullah MS,Tabassum S,Islam MN

    更新日期:2009-01-01 00:00:00

  • Isolation and identification of Aeromonas from patients with acute diarrhoea in Kolkata, India.

    abstract::Isolation of diarrhoea causing Aeromonas was carried out in the division of Active Surveillance, National Institute of Cholera and Enteric Diseases (NICED), Kolkata for a period of 12 months from January 1999 to December 1999. Out of 602 stool samples collected from patients with acute diarrhoea admitted in Infectious...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Kannan S,Chattopadhyay UK,Pal D,Shimada T,Takeda Y,Bhattacharya SK,Ananthanarayanan PH

    更新日期:2001-10-01 00:00:00

  • Necrotizing (malignant) otitis externa: an unusual localization of mucormycosis.

    abstract::Malignant otitis externa (MOE) is a severe infection of external auditory canal and skull base. A 17-year-old diabetic girl was admitted with diabetic ketoacidosis. Cellulitis of her right ear occurred on the second day of hospitalization and a black necrotic scar in the same region appeared on the next day. The lesio...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.29390

    authors: Tuzcu A,Bahceci M,Celen MK,Kilinc N,Ozmen S

    更新日期:2006-10-01 00:00:00

  • Evaluation of a modified double-disc synergy test for detection of extended spectrum beta-lactamases in AMPC beta-lactamase-producing proteus mirabilis.

    abstract::The detection of extended-spectrum beta-lactamases (ESBLs) in gram-negative bacteria that produce AmpC beta-lactamases is problematic. In the present study, the performance of modified double-disc synergy test (MDDST) that employs a combination of cefepime and piperacillin-tazobactam for the detection of Proteus mirab...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.38860

    authors: Khan MK,Thukral SS,Gaind R

    更新日期:2008-01-01 00:00:00

  • Unimicrobial appendicitis due to non-vaccine serotype of streptococcus pneumoniae: Implications for and management and prevention.

    abstract::The aetiology of appendicitis is usually polymicrobial. We report a rare case of appendicitis caused by Streptococcus pneumoniae as the only causative organism. The case assumes significance because it occurs in the absence of any predisposing factor for invasive pneumococcal infection, it is unimicrobial, it may lead...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Bhattacharya S,Kanungo R,Natarajan MK,Mahalakshmi VN,Srinivasan K

    更新日期:2001-04-01 00:00:00

  • Cutaneous infection with Mycobacterium fortuitum: an unusual presentation.

    abstract::Cutaneous infection with rapidly growing mycobacteria is uncommon and its diagnosis can be missed unless there is strong clinical suspicion coupled with microbiological confirmation. We report a case of localized recurrent soft tissue swelling of the foot by Mycobacterium fortuitum in a healthy adult male. The case is...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.43571

    authors: Sarma S,Thakur R

    更新日期:2008-10-01 00:00:00

  • A case of tuberculous pericardial effusion.

    abstract::Tuberculosis accounts for up to 4% of acute pericarditis and 7% cases of cardiac tamponade. Prompt treatment can be life saving but requires accurate diagnosis. We report a case of 30-year-old male who presented with fever, chills, and dry nonproductive cough since one month. The case was diagnosed by radiological fin...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Wanjari K,Baradkar V,Mathur M,Kumar S

    更新日期:2009-01-01 00:00:00

  • Evaluation of biphasic culture system for mycobacterial isolation from the sputum of patients with pulmonary tuberculosis.

    abstract::Mycobacterial diseases continue to cause high morbidity and mortality. Isolation, identification and sensitivity testing form the backbone of laboratory investigations. M. tuberculosis isolation needs 6-8 weeks on conventional egg containing media. For rapid isolation various methods have been evaluated. We evaluated ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.16050

    authors: Ghatole M,Sable C,Kamale P,Kandle S,Jahagirdar V,Yemul V

    更新日期:2005-04-01 00:00:00

  • Ludwig's angina by Salmonella Typhi: a clinical dilemma.

    abstract::Salmonella Typhi has rarely been associated with focal abscesses; and in literature, there is no evidence of its association with abscesses in the neck spaces. Ability of Salmonella Typhi to invade and localise in the neck spaces not only poses a diagnostic challenge but also underscores the necessity to understand th...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.154889

    authors: Mahajan RK,Sharma S,Madan P,Sharma N

    更新日期:2015-04-01 00:00:00

  • Neonatal listeriosis followed by nosocomial infection.

    abstract::Neonatal listeriosis is widely reported, but this is the first case reported in Serbia. A newborn developed respiratory distress syndrome 2 hours after delivery and was admitted to the neonatal intensive care unit. Initial empirical therapy was inappropriate. Consequently, on the second day, the patient developed meni...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.115229

    authors: Dinic M,Stankovic S

    更新日期:2013-04-01 00:00:00

  • Epidemiology and risk factors associated with NTM pulmonary and extrapulmonary infections in a high tuberculosis endemic Region.

    abstract:Introduction:Non-tuberculous mycobacteria, although identified as pathogenic to humans long time ago, are emerging as the new threat in the past two decades. Even in tuberculosis endemic country such as India, they are being isolated from the clinical specimens more often than previously. This change in trend is of con...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_20_274

    authors: Wani SR,Wattal C,Raveendran R

    更新日期:2020-04-01 00:00:00

  • Superantigens - concepts, clinical disease and therapy.

    abstract::The term superantigen was introduced in microbiology and immunology only a decade ago. The unique feature of superantigen is that it bypasses the antigen processing mechanism and specifically binds to TCR v segment and forms a trimolecular complex along with major histocompatibility complex class II. Since its discove...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Hemalatha V,Srikanth P,Mallika M

    更新日期:2004-10-01 00:00:00

  • Simple and economical method for speciation and resistotyping of clinically significant coagulase negative staphylococci.

    abstract::An attempt was made to speciate 102 clinically significant isolates of coagulase negative staphylococci (CoNS) by a practical scheme adapted from various references. This scheme utilizes slide and tube coagulase test, urease test ornithine decarboxylase, novobiocin susceptibility and aerobic acid from mannose for assi...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Goyal R,Singh NP,Kumar A,Kaur I,Singh M,Sunita N,Mathur M

    更新日期:2006-07-01 00:00:00

  • The presence of dsRNA virus in Trichomonas vaginalis isolates from symptomatic and asymptomatic Indian women and its correlation with in vitro metronidazole sensitivity.

    abstract:PURPOSE:Trichomonas vaginalis, a protozoan parasite, is the causative agent of human trichomoniasis, the most common non-viral sexually transmitted disease. The infection encompasses from a complete asymptomatic presentation to severe sequelae; yet, the virulence markers have been poorly understood. It is suggested tha...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.81801

    authors: Malla N,Kaul P,Sehgal R,Gupta I

    更新日期:2011-04-01 00:00:00

  • Primary meningococcal arthritis of sacroiliac joint: a rare case report.

    abstract::Infection of the sacroiliac joint is a rare entity. Clinical signs and symptoms are usually nonspecific and result in delayed diagnosis. We report a rare case of primary meningococcal arthritis of right sacroiliac joint in an 11-year-old male child. Synovial fluid aspirated from the joint space showed Gram-negative di...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.108743

    authors: Sahu S,Mohanty I,Narasimham MV,Pasupalak S,Parida B

    更新日期:2013-01-01 00:00:00

  • 16S rRNA PCR for differentiation of pathogenic and non-pathogenic leptospira isolates.

    abstract:PURPOSE:To determine the risk factors, microbiological features, clinical features and other epidemiological characteristics of Nocardia keratitis seen at a tertiary eye care centre in south India. METHODS:We evaluated 31 patients with Nocardia keratitis seen over two years, from September 1999 to September 2001. Corn...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Shukla J

    更新日期:2003-01-01 00:00:00

  • Group A rotavirus and bacterial agents associated with diarrhoea-induced hospitalisations in children below 5 years of age in Jammu.

    abstract::Out of 210 faecal samples collected from children below 5 years attending different hospitals in Jammu and exhibiting clinical signs of diarrhoea, 41.9% samples were found positive for group A rotavirus by RNA-PAGE. Escherichia coli isolated in the study belonged to nine serogroups, out of which O69 was most frequent,...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.124308

    authors: Gazal S,Taku A,Bhat MA,Badroo G

    更新日期:2014-01-01 00:00:00

  • Pancreatic abscess caused by s. typhi.

    abstract::A case of pancreatic abscess due to Salmonella typhi in a 40-year-old male is presented. The patient was managed by percutaneous needle aspiration and antibiotic therapy. ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Arya M,Arya PK

    更新日期:2001-04-01 00:00:00

  • Basidiobolomycosis: a rare case report.

    abstract::We report a rare case of basidiobolomycosis seen in an 11-year-old girl from North-Eastern part of India. She presented with complaints of bilateral nasal block and nasal discharge for seven-eight months. CT scan of sinuses revealed polypoidal mass in all the sinuses with extradural extension. The tissue biopsy examin...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Singh R,Xess I,Ramavat AS,Arora R

    更新日期:2008-07-01 00:00:00

  • Prevention of perinatal group B streptococcal infections: a review with an Indian perspective.

    abstract::Group B Streptococcus (GBS) is an important cause of maternal and neonatal morbidity and mortality in many parts of the world. Asymptomatic colonisation of the vagina and rectum with Group B streptococci is common in pregnancy. Maternal colonisation of GBS can vary depending on ethnicity and geographical distribution....

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章,评审

    doi:10.4103/0255-0857.124286

    authors: Narava S,Rajaram G,Ramadevi A,Prakash GV,Mackenzie S

    更新日期:2014-01-01 00:00:00

  • Acute abdomen: an unusual presentation of disseminated Penicillium marneffei infection.

    abstract::Varied clinical presentations of Penicillium marneffei, an opportunistic pathogen in HIV disease has been rarely described in literature. We report a patient with advanced AIDS who presented to us with prolonged fever and had features of an acute abdomen. On radiologic imaging he had features of intestinal obstruction...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.40538

    authors: George IA,Sudarsanam TD,Pulimood AB,Mathews MS

    更新日期:2008-04-01 00:00:00

  • Eumycetoma pedis due to Exophiala jeanselmei.

    abstract::A case of eumycetoma of foot in an 8-year old male child was clinically diagnosed as chronic osteomyelitis and was microbiologically confirmed as eumycetoma. The case is being reported for its uncommon clinical presentation and etiological agent, Exophiala jeanselmei. The patient recovered completely after treatment w...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.32726

    authors: Capoor MR,Khanna G,Nair D,Hasan A,Rajni,Deb M,Aggarwal P

    更新日期:2007-04-01 00:00:00

  • Serological diagnosis of dengue in laboratory practice in Kolkata.

    abstract:PURPOSE:To find out the most suitable serological investigative procedures to diagnose dengue cases effectively in the laboratory practice identifying primary and secondary cases as well as period of suffering. MATERIALS AND METHODS:Dengue suspected cases sent to the laboratory in 2012 in central Kolkata by the local ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.136563

    authors: Bhattacharya N,Mukherjee H,Naskar R,Talukdar S,Das G,Pramanik N,Hati AK

    更新日期:2014-07-01 00:00:00