Abstract：
:The term superantigen was introduced in microbiology and immunology only a decade ago. The unique feature of superantigen is that it bypasses the antigen processing mechanism and specifically binds to TCR v segment and forms a trimolecular complex along with major histocompatibility complex class II. Since its discovery, several studies have been carried out to unravel the properties of superantigens. They are implicated in the pathogenesis of diseases of bacterial, viral and fungal origin. They are also known to play a role in autoimmune diseases. Therapy for these superantigens is being worked upon. Studies have shown that intravenous gamma globulin containing specific antibodies to these superantigens inhibits the activation of T-Cells and also the cytokine production by them resulting in dramatic recovery from superantigen mediated diseases. The use of superantigen in the therapy of cancer is being explored.
journal_name
Indian J Med Microbioljournal_title
Indian journal of medical microbiologyauthors
Hemalatha V,Srikanth P,Mallika Msubject
Has Abstractpub_date
2004-10-01 00:00:00pages
204-11issue
4eissn
0255-0857issn
1998-3646journal_volume
22pub_type
杂志文章abstract：:Humanity has been at the receiving end of many viral diseases since ages. Sudden emergence and re-emergence of new viral diseases in human beings has surprised the medical scientists from time to time. "Avian influenza" or "Bird flu" by H5N1 epidemics is one such surprise. Although many aspects about this disease are ...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：
更新日期：2004-07-01 00:00:00
abstract：:Therapeutic options for the treatment of melioidosis caused by Burkholderia pseudomallei are limited due to the inherent resistance conferred by this pathogen to various groups of antibiotics. Witnessing an increase in the number of microbiological culture-confirmed cases of melioidosis at our settings in the past few...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.188340
更新日期：2016-07-01 00:00:00
abstract：:Human subcutaneous dirofilariasis is a rare infection caused by filarial worms of the genus Dirofilaria. The parasites are transmitted to man by mosquitoes and the infection is manifested as subcutaneous nodules. Excision of the lesion is both diagnostic and therapeutic. Hereby we report three cases of human subcutane...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章,评审
doi：10.4103/0255-0857.71836
更新日期：2010-10-01 00:00:00
abstract：:An attempt was made to speciate 102 clinically significant isolates of coagulase negative staphylococci (CoNS) by a practical scheme adapted from various references. This scheme utilizes slide and tube coagulase test, urease test ornithine decarboxylase, novobiocin susceptibility and aerobic acid from mannose for assi...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：
更新日期：2006-07-01 00:00:00
abstract：:The detection of extended-spectrum beta-lactamases (ESBLs) in gram-negative bacteria that produce AmpC beta-lactamases is problematic. In the present study, the performance of modified double-disc synergy test (MDDST) that employs a combination of cefepime and piperacillin-tazobactam for the detection of Proteus mirab...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.38860
更新日期：2008-01-01 00:00:00
abstract：PURPOSE:The Western Blot test is considered a gold standard test for the confirmation of an ELISA and/or rapid assay screened reactive sample in the diagnosis of HIV infection, especially in the low risk population. In this study, an indigenously developed HIV W. Blot kit (J.Mitra & Co., New Delhi, India) was compared ...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：
更新日期：2002-10-01 00:00:00
abstract：:Injection abscess is an iatrogenic infection occurring as an isolated case or as cluster outbreak. These infections occur due to contaminated injectables or lapse in sterilisation protocol. While pathogens such as Pseudomonas, Klebsiella, E. coli, and S. aureus are the usual causative agents, unusual organisms such as...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：
更新日期：2003-04-01 00:00:00
abstract：:We report a rare case of basidiobolomycosis seen in an 11-year-old girl from North-Eastern part of India. She presented with complaints of bilateral nasal block and nasal discharge for seven-eight months. CT scan of sinuses revealed polypoidal mass in all the sinuses with extradural extension. The tissue biopsy examin...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：
更新日期：2008-07-01 00:00:00
abstract：PURPOSE:To evaluate, the efficacy of BACTEC 460 TB system for the diagnosis of tuberculosis in a tertiary care hospital in Mumbai, India. METHODS:We compared 12,726 clinical specimens using BACTEC 460 TB system and conventional method for detection of Mycobacterium tuberculosis over a period of six years. RESULT:The ...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.31059
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:To examine the incidence of extended spectrum b lactamase (ESbL) producing strains and multidrug resistant strains of Klebsiella pneumoniae isolated from children between 0-5 years of age. METHODS:Multidrug resistance and ESbL production was studied in a total of 120 isolates of Klebsiella pneumoniae obtained ...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：
更新日期：2002-04-01 00:00:00
abstract：Purpose:The present study was undertaken to analyse the trend in prevalence of culture-positive typhoid fever during the last decade and to determine antimicrobial susceptibility profile of Salmonella Typhi and Salmonella Paratyphi A isolated from patients of enteric fever presenting to our hospital. Methods:All the c...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/ijmm.IJMM_17_412
更新日期：2018-01-01 00:00:00
abstract：PURPOSE:The present study was undertaken to detect metallo-beta-lactamase (MBL) in nosocomial isolates of Pseudomonas aeruginosa by four different phenotypic methods. METHODS:Ninety-one consecutive P. aeruginosa isolates were subjected to susceptibility testing by disc-diffusion assay and Vitek 2. Imipenem resistance ...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.39587
更新日期：2008-07-01 00:00:00
abstract：PURPOSE:Vancomycin-resistant enterococci (VRE) pose an emerging problem in hospitals worldwide. The present study was undertaken to determine the occurrence, species prevalence, antibacterial resistance, and phenotypic and genetic characteristics of VRE isolated in Riyadh hospitals, KSA. MATERIALS AND METHODS:Two hund...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.93032
更新日期：2012-01-01 00:00:00
abstract：:We report a case of a 30-year-old immunocompetent man with disseminated cryptococcosis who was initially treated with antitubercular therapy due to clinical and radiological diagnosis of vertebro-cerebral tuberculosis. The diagnosis of Cryptococcus infection was made due to incidental isolation of this fungus from blo...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.96715
更新日期：2012-04-01 00:00:00
abstract：INTRODUCTION:The chances of health care waste (Biomedical waste) coming in contact with the health care workers, patients, visitors, sanitary workers, waste handlers, public, rag pickers and animals during transportation are high. MATERIALS AND METHODS:The study was conducted over a period of seven months (April 2013-...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.158559
更新日期：2015-07-01 00:00:00
abstract：:Invasive candidiasis is a life-threatening complication of critically ill immunocompromised patients with high attributable mortality. Due to non-specific clinical presentation, early detection of candidemia and accurate identification of Candida species are essential pre-requisites for improved therapeutic outcome. S...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章,评审
doi：10.4103/0255-0857.99482
更新日期：2012-07-01 00:00:00
abstract：Introduction:The TORCH infections during pregnancy are associated with adverse congenital abnormalities, poor foetal outcome and subsequent reproductive failures. The absence of baseline data on status of TORCH infections and associated foetal outcomes prompted us to conduct the current study in Central India. Materia...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/ijmm.IJMM_20_136
更新日期：2020-07-01 00:00:00
abstract：:Extended spectrum -lactamases (ESBLs) are plasmid mediated, TEM and SHV derived enzymes, first isolated in Western Europe in mid 1980s, most commonly in Klebsiella spp., followed by Escherichia coli. These enzymes are capable of hydrolyzing broad spectrum cephalosporins and monobactams but inactive against cephamycins...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：
更新日期：2004-04-01 00:00:00
abstract：:The surveillance in Chennai identified 134 children and 443 adults clinically suspected for leptospirosis. Of these, 35 (26.1%) children and 118 (26.6%) adults had laboratory confirmed diagnosis for leptospirosis. The paediatric leptospirosis exhibited a higher frequency of classic features of Weil's disease. The prev...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.180353
更新日期：2016-04-01 00:00:00
abstract：:Tubercular brain abscess are uncommon and tubercular cerebellar abscess are rarely reported. Most of these cases occur in immunocompromised patients. We report a case of multiple cerebellar abscesses in a 55-year-old HIV seronegative non-diabetic female, who complained of headache, neck pain and unsteadiness of gait s...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.55464
更新日期：2009-10-01 00:00:00
abstract：PURPOSE:To evaluate the utility of the polymerase chain reaction (PCR) test for diagnosing osteoarticular tuberculosis (TB). METHODS:Clinical samples (synovial tissue and synovial fluid) obtained from 23 cases of suspected osteoarticular tuberculosis were subjected to Ziehl Neelsen (ZN) smear examination, radiometric ...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：
更新日期：2005-10-01 00:00:00
abstract：:Microbiological contamination of blood and blood products is a well-recognised transfusion risk. This study was performed in the blood bank of our oncology centre, with an objective to detect bacterial contamination in our blood products using oxygen consumption as a surrogate marker [Pall Enhanced Bacterial Detection...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.96695
更新日期：2012-04-01 00:00:00
abstract：:Varied clinical presentations of Penicillium marneffei, an opportunistic pathogen in HIV disease has been rarely described in literature. We report a patient with advanced AIDS who presented to us with prolonged fever and had features of an acute abdomen. On radiologic imaging he had features of intestinal obstruction...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.40538
更新日期：2008-04-01 00:00:00
abstract：Objectives:Levonadifloxacin is a novel benzoquinolizine subclass of quinolone with broad-spectrum activities against problematic pathogens such as methicillin-resistant Staphylococcus aureus, quinolone-resistant S. aureus, vancomycin intermediate S. aureus, and vancomycin-resistant S. aureus. Levonadifloxacin and its o...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/ijmm.IJMM_20_307
更新日期：2020-07-01 00:00:00
abstract：:Aspergilloma is a fungal ball that usually forms in a preformed stationary cavity, mostly in lung and paranasal sinuses. We report a rare case of primary orbital Aspergilloma following exenteration for an invasive ocular surface squamous neoplasia, clinically mimicking a recurrence of the tumor. The fungal ball showed...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：
更新日期：2006-07-01 00:00:00
abstract：:Neonatal listeriosis is widely reported, but this is the first case reported in Serbia. A newborn developed respiratory distress syndrome 2 hours after delivery and was admitted to the neonatal intensive care unit. Initial empirical therapy was inappropriate. Consequently, on the second day, the patient developed meni...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.115229
更新日期：2013-04-01 00:00:00
abstract：PURPOSE:To describe the changes in antibiotic susceptibility patterns of common intensive care unit pathogens with time from the medical intensive care unit of a tertiary care hospital. METHODS:A prospective observational study was conducted in the medical intensive care unit (MICU) of a 2100 bed tertiary care hospita...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.34764
更新日期：2007-07-01 00:00:00
abstract：:We evaluated the incidence and risk factors of Staphylococcus aureus colonisation in 300 treatment-naïve HIV patients. Swabs from anterior nares and pharynx were cultured. Eighty-eight patients (29.3%) were colonised with S. aureus (47.7% nasal, 23.8% pharyngeal and 28.5% at both sites), which yielded 112 isolates. Me...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/ijmm.IJMM_20_5
更新日期：2020-07-01 00:00:00
abstract：:A 23-year-old male patient who was a follow-up case of neurosurgery presented to our emergency department with a history of high-grade fever and clinical features of meningitis for 1 week. The cerebrospinal fluid (CSF) was sent to our laboratory for culture. The culture demonstrated growth of 1-2 mm in diameter light ...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.115653
更新日期：2013-07-01 00:00:00
abstract：:We report the first case of prosthetic joint infection caused by Lysobacter thermophilus which was identified by 16S rRNA gene sequencing. Removal of prosthesis followed by antibiotic treatment resulted in good clinical outcome. This case illustrates the use of molecular diagnostics to detect uncommon organisms in sus...
journal_title：Indian journal of medical microbiology
pub_type： 杂志文章
doi：10.4103/0255-0857.174124
更新日期：2016-01-01 00:00:00
